Selective orexin receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 17, 2013, Pages 4761-4769

  Lebold, Terry P ^a   Bonaventure, Pascal ^a   Shireman, Brock T ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Hcrt 1; Hcrt 2; Hypocretin; Hypothalamus; Orexin

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; 1 (6,8 DIFLUORO 2 METHYL 4 QUINOLINYL) 3 (4 DIMETHYLAMINOPHENYL)UREA; ALMOREXANT; FILOREXANT; GSK 1059865; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; SB 410220; SB 649868; SB 674042; SUVOREXANT; UNCLASSIFIED DRUG;

ARTICLE; HUMAN; INSOMNIA; MAJOR DEPRESSION; MENTAL DISEASE; MIGRAINE; MUTAGENESIS; NONHUMAN; SLEEP; STRUCTURE ACTIVITY RELATION;

HCRT-1; HCRT-2; HYPOCRETIN; HYPOTHALAMUS; OREXIN;

ANIMALS; DRUG DISCOVERY; HUMANS; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEUROPEPTIDES; OREXIN RECEPTORS; SMALL MOLECULE LIBRARIES;

EID: 84881368759     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.06.057     Document Type: Review

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