N-Acyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline: The first orexin-2 receptor selective non-peptidic antagonist

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 24, 2003, Pages 4497-4499

  Hirose, Masaaki ^a   Egashira, Shin Ichiro ^a   Goto, Yasuhiro ^a   Hashihayata, Takashi ^a   Ohtake, Norikazu ^a   Iwaasa, Hisashi ^a   Hata, Mikiko ^a   Fukami, Takehiro ^a   Kanatani, Akio ^a   Yamada, Koji ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE; N ACYL 6,7 DIMETHOXY 1,2,3,4 TETRAHYDROISOQUINOLONE; OREXIN; OREXIN 2 RECEPTOR; RECEPTOR SUBTYPE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CHEMICAL MODIFICATION; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SOLUBILITY; PROTEIN ANALYSIS; SCREENING; SUBSTITUTION REACTION;

EID: 0344927037     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.08.038     Document Type: Article

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