Anticancer effects of flavonoid derivatives isolated from millettia reticulata benth in sk-hep-1 human hepatocellular carcinoma cells

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 2, 2010, Pages 814-820

  Fang, Song Chwan ^a   Hsu, Chin Lin ^b   Lin, Hsin Tang ^c   Yen, Gow Chin ^d  

^a CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c SHIH CHIEN UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Genistein; Millettia reticulata benth; Sk hep 1 cells

Indexed keywords

ANTINEOPLASTIC AGENT; FLAVONOID; PLANT EXTRACT;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMAN; ISOLATION AND PURIFICATION; MILLETTIA; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MILLETTIA; PLANT EXTRACTS;

MILLETTIA;

EID: 74849137845     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf903216r     Document Type: Article

References (33)

1. Johnstone, R. W.; Ruefli, A. A.; Lowe, S. W. Apoptosis: a link between cancer genetics and chemotherapy. Cell 2002, 108, 153-164.
2. Thornberry, N. A.; Rano, T. A.; Peterson, E. P.; Rasper, D. M.; Timkey, T.; Garcia-Calvo, M.; Houtzager, V. M.; Nordstrom, P. A.; Roy, S.; Vaillancourt, J. P.; Chapman, K. T.; Nicholson, D. W. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 1997, 272, 17907-17911.
3. Li, P.; Nijhawan, D.; Budihardjo, J.; Srinivasula, S. M.; Ahmad, M.; Alnewri, E. S.; Wang, X. Cytochrome c and ATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic proteasome cascade. Cell 1997, 91, 479-489.
4. Green, D. R.; Reed, J. C. Mitochondria and apoptosis. Science 1998, 281, 1309-1312.
5. Raghuvar Gopal, D. V.; Narkar, A. A.; Badrinath, Y.; Mishra, K. P.; Joshi, D. S. Protection of Ewing's sarcoma family tumor (ESFT) cell line SK-N-MC from betulinic acid induced apoptosis by R-DL-tocopherol. Toxicol Lett. 2004, 153, 201-212. (Pubitemid 39296976)
6. Zamzami, N.; Metivier, D.; Kroemer, G. Quantitation of mitochondrial transmembrane potential in cells and isolated mitochondria. Methods Enzymol. 2000, 322, 208-213. (Pubitemid 30482057)
7. Chen, Y. P.; Chen, C. C.; Hsu, H. Y. Pharmacological activities of the flavonoids of Bauhinia championii and Millettia reticulata. prog. Clin. Biol. Res. 1986, 213, 297-300.
8. Lee, M. H.; Lin, Y. P.; Hsu, F. L.; Zhan, G. R.; Yen, K. Y. Bioactive constituents of Spatholobus suberectus in regulating tyrosinaserelated proteins and m RNA in HEMn cells. Phytochemistry 2006, 67, 1262-1270.
9. Cheng, J.; Liang, H.; Wang, Y.; Zhao, Y. Y. Studies on the constituents from the stems of Spatholobus suberectus. Zhongguo Zhong Yao Za Zhi 2003, 28, 1153-1155.
10. Lee, J. Y.; Kang, W. H. Effect of cyclosporin A on melanogenesis in cultured human melanocytes. Pigment Cell Res. 2003, 16, 504-508. (Pubitemid 37093028)
11. Li, R. W.; David Lin, G.; Myers, S. P.; Leach, D. N. Antiinflammatory activity of Chinese medicinal vine plants. J. Ethnopharmacol. 2003, 55, 61-67. (Pubitemid 36170057)
12. Chen, D. H.; Luo, X.; Yu, M. Y.; Zhao, Y. Q.; Cheng, Y. F.; Yang, Z. R. Effect of Spatholobus suberectus on the bone marrow cells and related cytokines of mice. Zhongguo Zhong Yao Za Zhi 2004, 29, 352-355.
13. Hsu, C. C.; Hsu, C. L.; Tsai, S. E.; Fu, T. Y.; Yen, G. C. Protective effect of Millettia reticulata Benth against CCl(4)-induced hepatic damage and inflammatory action in rats. J. Med. Food 2009, 12, 821-828.
14. Zhou, S.; Hu, Y.; Zhang, B.; Teng, Z.; Gan, H.; Yang, Z.; Wang, Q.; Huan, M.; Mei, Q. Dose-dependent absorption, metabolism, and excretion of genistein in rats. J. Agric. Food Chem. 2008, 56, 8354-8359.
15. (15) Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63. (Pubitemid 14203433)
16. Nunes, D. S.; Haag, A.; Bestmann, H. J. Two proanthocyanidins from the bark of Dalbergia monetaria. Phytochemistry 1989, 28, 2183-2186.
17. Yoshinari, K.; Shimazaki, N.; Sashida, Y.; Mimaki, Y. Flavanone xyloside and lignans from Prunus jamasakura bark. Phytochemistry 1990, 29, 1675-1678.
18. Zheng, Z. P.; Cheng, K. W.; Chao, J.; Wu, J.; Wang, M. Tyrosinase inhibitors from paper mulberry (Broussonetia papyrifera). Food Chem. 2008, 106, 529-535.
19. Herath, H. M. T. B.; Dassanayake, R. S.; Priyadarshani, M. A.; Silva, S. D.; Wannigama, G. P. Isoflavonoids and a pterocarpan from Gliricidia sepium. Phytochemistry 1998, 47, 117-119.
20. Takasugi, M.; Niino, N.; Nagao, S.; Anetai, M.; Masamune, T.; Shirata, A.; Takahashi, K. Eight minor phytoalexins from diseased paper mulberry. Chem. Lett. 1984, 13, 689-692.
21. Khalid, S. A.; Gellert, M.; Szendrei, K.; Duddeck, H. Prunetin-5-Oβ-D-glucopyranoside, an isoflavone from the peduncle of Prunus avium and P. cerasus. Phytochemistry 1989, 28, 1560-1561.
22. Po, L. S.; Wang, T. T.; Chen, Z. Y.; Leung, L. K. Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects. Br. J. Nutr. 2002, 88, 463-469.
23. Kim, E. J.; Shin, H. K.; Park, J. H. Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of genistein. J. Med. Food 2005, 8, 431-438.
24. Chodon, D.; Ramanurty, N.; Sakthisekaran, D. Preliminary studies on induction of apoptosis by genistein on HepG2 cell line. Toxicol. In Vitro 2007, 21, 887-891. (Pubitemid 46603234)
25. Sánchez, Y.; Amrán, D.; Fernández, C.; de Blas, E.; Aller, P. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38MAPK, AMPK). Int. J. Cancer 2008, 123, 1205-1214.
26. Yeh, T. C.; Chiang, P. C.; Li, T. K.; Hsu, J. L.; Lin, C. J.; Wang, S. W.; Peng, C. Y.; Guh, J. H. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. Biochem. Pharmacol. 2007, 73, 782-792.
27. Vermeulen, K.; Van Bockstaele, D. R.; Berneman, Z. N. Apoptosis: mechanisms and relevance in cancer Ann. Hematol. 2005, 84, 627-639. (Pubitemid 41554237)
28. Hunt, A.; Evan, G. Apoptosis. Till death us do part. Science 2001, 293, 1784-1785.
29. Merry, D. E.; Korsmeyer, S. J. Bcl-2 gene family in the nervous system. Annu. Rev. Neurosci. 1997, 20, 245-267.
30. Salvesen, G. S.; Dixit, V. M. Caspases: intracellular signaling by proteolysis. Cell 1997, 91, 443-446.
31. Debatin, K. M.; Krammer, P. H. Death receptors in chemotherapy and cancer. Oncogene 2004, 23, 2950-2966.
32. Oh, J. I.; Chun, K. H.; Joo, S. H.; Oh, Y. T.; Lee, S. K. Caspase-3dependent protein kinase C delta activity is required for the progression of ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells. Cancer Lett. 2005, 230, 228-238.
33. Jung, M. Y.; Kwon, S. K.; Moon, A. Chemopreventive allylthiopyridazine derivatives induce apoptosis in SK-Hep-1 hepatocarcinoma cells through a caspase-3-dependent mechanism. Eur. J. Cancer 2001, 37, 2104-2110. (Pubitemid 32938116)