-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61(2): 69-90, 2011.
-
(2011)
CA Cancer J Clin
, vol.61
, Issue.2
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
34047222991
-
Comparison of multidrug resistant efflux pumps of cancer and bacterial cells with respect to the same inhibitory agents
-
Amaral L, Engi H, Viveiros M and Molnar J: Comparison of multidrug-resistant efflux pumps of cancer and bacterial cells with respect to the same inhibitory agents. In Vivo 21: 237-244, 2007. (Pubitemid 46534275)
-
(2007)
In Vivo
, vol.21
, Issue.2
, pp. 237-244
-
-
Amaral, L.1
Engi, H.2
Viveiros, M.3
Molnar, J.4
-
3
-
-
78651376221
-
Evolution of ABC transporters by gene duplication and their role in human disease
-
Moitra K and Dean M: Evolution of ABC transporters by gene duplication and their role in human disease. Biol Chem 392: 29-37, 2011.
-
(2011)
Biol Chem
, vol.392
, pp. 29-37
-
-
Moitra, K.1
Dean, M.2
-
4
-
-
67650656774
-
Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: Evaluation of current strategies
-
Wu CP, Calcagno AM and Ambudkar SV: Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies. Curr Mol Pharmacol 1: 93-105, 2008
-
(2008)
Curr Mol Pharmacol
, vol.1
, pp. 93-105
-
-
Wu, C.P.1
Calcagno, A.M.2
Ambudkar, S.V.3
-
5
-
-
27844580268
-
Multiple drug resistance, antimutagenesis and anticarcinogenesis
-
DOI 10.1016/j.mrfmmm.2005.02.030, PII S0027510705003180, Mechanistic Approaches to Chemoprevention of Mutation and Cancer
-
Ferguson LR and De Flora S: Multiple drug resistance, antimutagenesis and anticarcinogenesis. Mutat Res 591: 24-33, 2005. (Pubitemid 41654837)
-
(2005)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.591
, Issue.1-2
, pp. 24-33
-
-
Ferguson, L.R.1
De Flora, S.2
-
6
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins CF: ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8: 67-113, 1992.
-
(1992)
Annu Rev Cell Biol
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
7
-
-
33749488939
-
Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
-
DOI 10.1152/physrev.00037.2005
-
Sarkadi B, Homolya L, Szakács G and Váradi A: Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 86: 1179-1236, 2006. (Pubitemid 44521651)
-
(2006)
Physiological Reviews
, vol.86
, Issue.4
, pp. 1179-1236
-
-
Sarkadi, B.1
Homolya, L.2
Szakacs, G.3
Varadi, A.4
-
8
-
-
5144226566
-
Predicting drug sensitivity and resistance: Profiling ABC transporter genes in cancer cells
-
DOI 10.1016/j.ccr.2004.06.026, PII S1535610804002065
-
Szakács G, Annereau JP, Lababidi S, Shankavaram U, Arciello A, Bussey KJ, Reinhold W, Guo Y, Kruh GD, Reimers M, Weinstein JN and Gottesman MM: Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells. Cancer Cell 6: 129-137, 2004. (Pubitemid 39485685)
-
(2004)
Cancer Cell
, vol.6
, Issue.2
, pp. 129-137
-
-
Szakacs, G.1
Annereau, J.-P.2
Lababidi, S.3
Shankavaram, U.4
Arciello, A.5
Bussey, K.J.6
Reinhold, W.7
Guo, Y.8
Kruh, G.D.9
Reimers, M.10
Weinstein, J.N.11
Gottesman, M.M.12
-
10
-
-
84903754700
-
Papers reprinted
-
Himmelweit F, Marquardt M and Dale HH (eds.), Chemotherapy: London: Pergamon
-
Ehrlich P: Papers reprinted. In: The Collected Papers of Paul Ehrlich. Himmelweit F, Marquardt M and Dale HH (eds.), Vol III. Chemotherapy: London: Pergamon pp. 505-518, 1913.
-
(1913)
The Collected Papers of Paul Ehrlich
, vol.3
, pp. 505-518
-
-
Ehrlich, P.1
-
12
-
-
0030801767
-
The potential management of resistant infections with non-antibiotics
-
DOI 10.1093/jac/40.3.319
-
Kristiansen JE and Amaral L: The potential management of resistant infections with non-antibiotics. J Antimicrob Chemother 40: 319-327, 1997. (Pubitemid 27437949)
-
(1997)
Journal of Antimicrobial Chemotherapy
, vol.40
, Issue.3
, pp. 319-327
-
-
Kristiansen, J.E.1
Amaral, L.2
-
13
-
-
0034072946
-
Phenothiazines: An alternative to conventional therapy for the initial management of suspected multidrug resistant tuberculosis. A call for studies
-
DOI 10.1016/S0924-8579(99)00153-3, PII S0924857999001533
-
Amaral L and Kristiansen JE: Phenothiazines: an alternative to conventional therapy for the initial management of suspected multidrug resistant tuberculosis. A call for studies. Int J Antimicrob Agents 14: 173-176, 2000. (Pubitemid 30201540)
-
(2000)
International Journal of Antimicrobial Agents
, vol.14
, Issue.3
, pp. 173-176
-
-
Amaral, L.1
Kristiansen, J.E.2
-
14
-
-
0035010729
-
Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: A review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy
-
Amaral L, Kristiansen JE, Viveiros M and Atouguia J: Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy. J Antimicrob Chemother 47: 505-511, 2001.
-
(2001)
J Antimicrob Chemother
, vol.47
, pp. 505-511
-
-
Amaral, L.1
Kristiansen, J.E.2
Viveiros, M.3
Atouguia, J.4
-
15
-
-
0035172946
-
Phenothiazines: Potential management of Creutzfeldt-Jacob disease and its variants
-
Amaral A, Kristiansen JE: Phenothiazines: potential management of Creutzfeldt-Jacob disease and its variants. Int J Antimicrob Agents 18: 411-417, 2001.
-
(2001)
Int J Antimicrob Agents
, vol.18
, pp. 411-417
-
-
Amaral, A.1
Kristiansen, J.E.2
-
16
-
-
0035657318
-
Phenothiazines: Potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries
-
DOI 10.1046/j.1365-3156.2001.00804.x
-
Amaral L, Viveiros M and Kristiansen JE: Phenothiazines: potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries. Trap Med Int Health 6: 1016-1022, 2001. (Pubitemid 34008769)
-
(2001)
Tropical Medicine and International Health
, vol.6
, Issue.12
, pp. 1016-1022
-
-
Amaral, L.1
Viveiros, M.2
Kristiansen, J.E.3
-
18
-
-
0022615254
-
Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine
-
Akiyama S, Shiraishi N, Kuratomi Y, Nakagawa M and Kuwano M: Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine. J Natl Cancer Inst 76: 839-844, 1986. (Pubitemid 16121940)
-
(1986)
Journal of the National Cancer Institute
, vol.76
, Issue.5
, pp. 839-844
-
-
Akiyama, S.-I.1
Shiraishi, N.2
Kuratomi, Y.3
-
19
-
-
0026593795
-
Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells: Relationship to free radicals and lipid peroxidation and its modulation by calmodulin antagonists
-
Sagar PS, Das UN, Koratkar R, Ramesh G, Padma M and Kumar GS: Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells: relationship to free radicals and lipid peroxidation and its modulation by calmodulin antagonists. Cancer Lett 63: 189-198, 1992.
-
(1992)
Cancer Lett
, vol.63
, pp. 189-198
-
-
Sagar, P.S.1
Das, U.N.2
Koratkar, R.3
Ramesh, G.4
Padma, M.5
Kumar, G.S.6
-
20
-
-
0028243997
-
Chlorpromazine in combination with nitrosourea inhibits experimental glioma growth
-
Aas AT, Brun A, Pero RW and Salford LG: Chlorpromazine in combination with nitrosourea inhibits experimental glioma growth. Br J Neurosurg 8: 187-192, 1994. (Pubitemid 24160003)
-
(1994)
British Journal of Neurosurgery
, vol.8
, Issue.2
, pp. 187-192
-
-
Aas, A.T.1
Brun, A.2
Pero, R.W.3
Salford, L.G.4
-
21
-
-
0028556658
-
Effect of anti-calmodulin drugs on the growth and sensitivity of C6 rat glioma cells to bleomycin
-
Hait WN, Gesmonde JF and Lazo JS: Effect of anti-calmodulin drugs on the growth and sensitivity of C6 rat glioma cells to bleomycin. Anticancer Res 14: 1711-1721, 1994.
-
(1994)
Anticancer Res
, vol.14
, pp. 1711-1721
-
-
Hait, W.N.1
Gesmonde, J.F.2
Lazo, J.S.3
-
22
-
-
0030023901
-
Successful cancer therapy with promethazine: The rationale
-
Jones GR: Successful cancer therapy with promethazine: the rationale. Med Hypotheses 46: 25-29, 1996.
-
(1996)
Med Hypotheses
, vol.46
, pp. 25-29
-
-
Jones, G.R.1
-
23
-
-
78649905860
-
A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3′kinase (PI3K)/AKT pathway in ovarian cancer cells
-
Rho SB, Kim BR and Kang S: A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3′kinase (PI3K)/AKT pathway in ovarian cancer cells. Gynecol Oncol 120: 121-127, 2011.
-
(2011)
Gynecol Oncol
, vol.120
, pp. 121-127
-
-
Rho, S.B.1
Kim, B.R.2
Kang, S.3
-
24
-
-
33644874300
-
Phenothiazines induce apoptosis in a B16 mouse melanoma cell line and attenuate in vivo melanoma tumor growth
-
Gil-Ad I, Shtaif B, Levkovitz Y, Nordenberg J, Taler M, Korov I and Weizman A: Phenothiazines induce apoptosis in a B16 mouse melanoma cell line and attenuate in vivo melanoma tumor growth. Oncol Rep 15: 107-112, 2006.
-
(2006)
Oncol Rep
, vol.15
, pp. 107-112
-
-
Gil-Ad, I.1
Shtaif, B.2
Levkovitz, Y.3
Nordenberg, J.4
Taler, M.5
Korov, I.6
Weizman, A.7
-
25
-
-
0026775668
-
Tamoxifen-resistant human breast cancer cell growth: Inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13
-
Strobl JS and Peterson VA: Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. J Pharmacol Exp Ther 263: 186-193, 1992.
-
(1992)
J Pharmacol Exp Ther
, vol.263
, pp. 186-193
-
-
Strobl, J.S.1
Peterson, V.A.2
-
26
-
-
65649121136
-
Design of new drug molecules to be used in reversing multidrug resistance in cancer cells
-
Mayur YC, Peters GJ, Prasad VV, Lemo C and Sathish NK: Design of new drug molecules to be used in reversing multidrug resistance in cancer cells. Curr Cancer Drug Targets 9: 298-306, 2009.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 298-306
-
-
Mayur, Y.C.1
Peters, G.J.2
Prasad, V.V.3
Lemo, C.4
Sathish, N.K.5
-
27
-
-
38849207033
-
2+/CaM-dependent protein kinase cascade in health and disease
-
2+/CaM- dependent protein kinase cascade in health and disease. Subcell Biochem 45: 169-214, 2007.
-
(2007)
Subcell Biochem
, vol.45
, pp. 169-214
-
-
Colomer, J.1
Means, A.R.2
-
28
-
-
33845386823
-
Targeting calmodulin in reversing multi drug resistance in cancer cells
-
DOI 10.2174/138955706778993021
-
Mayur YC, Jagadeesh S and Thimmaiah KN: Targeting calmodulin in reversing multi-drug resistance in cancer cells. Mini Rev Med Chem 6: 1383-1389, 2006. (Pubitemid 44890545)
-
(2006)
Mini-Reviews in Medicinal Chemistry
, vol.6
, Issue.12
, pp. 1383-1389
-
-
Mayur, Y.C.1
Jagadeesh, S.2
Thimmaiah, K.N.3
-
29
-
-
23644455002
-
Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy
-
DOI 10.1517/14728222.9.4.791
-
Rodriguez-Mora O, LaHair MM, Howe CJ, McCubrey JA and Franklin RA: Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy. Expert Opin Ther Targets 9: 791-808, 2005. (Pubitemid 41131679)
-
(2005)
Expert Opinion on Therapeutic Targets
, vol.9
, Issue.4
, pp. 791-808
-
-
Rodriguez-Mora, O.1
LaHair, M.M.2
Howe, C.J.3
McCubrey, J.A.4
Franklin, R.A.5
-
30
-
-
0030462751
-
Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: Potential use for initial therapy of freshly diagnosed tuberculosis
-
DOI 10.1093/jac/38.6.1049
-
Amaral L, Kristiansen JE, Abebe LS and Millett W: Inhibition of the respiration of multidrug-resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed tuberculosis. J Antimicrob Chemother 38: 1049-1053, 1996. (Pubitemid 27073284)
-
(1996)
Journal of Antimicrobial Chemotherapy
, vol.38
, Issue.6
, pp. 1049-1053
-
-
Amaral, L.1
Kristiansen, J.E.2
Abebe, L.S.3
Millett, W.4
-
31
-
-
78751480306
-
Biological activity of hydantoin derivatives on P-glycoprotein (ABCB1) of mouse lymphoma cells
-
Spengler G, Evaristo M, Handzlik J, Serly J, Molnár J, Viveiros M, Kiéc-Kononowicz K and Amaral L: Biological activity of hydantoin derivatives on P-glycoprotein (ABCB1) of mouse lymphoma cells. Anticancer Res 30: 4867-4871, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 4867-4871
-
-
Spengler, G.1
Evaristo, M.2
Handzlik, J.3
Serly, J.4
Molnár, J.5
Viveiros, M.6
Kiéc-Kononowicz, K.7
Amaral, L.8
-
32
-
-
71949083688
-
Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry
-
Spengler G, Ramalhete C, Martins M, Martins A, Serly J, Viveiros M, Molnár J, Duarte N, Mulhovo S, Ferreira MJ and Amaral L: Evaluation of cucurbitane-type triterpenoids from Momordica balsamina on P-glycoprotein (ABCB1) by flow cytometry and real-time fluorometry. Anticancer Res 29: 3989-3993, 2009.
-
(2009)
Anticancer Res
, vol.29
, pp. 3989-3993
-
-
Spengler, G.1
Ramalhete, C.2
Martins, M.3
Martins, A.4
Serly, J.5
Viveiros, M.6
Molnár, J.7
Duarte, N.8
Mulhovo, S.9
Ferreira, M.J.10
Amaral, L.11
-
33
-
-
67650895867
-
Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method
-
Spengler G, Viveiros M, Martins M, Rodrigues L, Martins A, Molnar J, Couto I and Amaral L: Demonstration of the activity of P-glycoprotein by a semi-automated fluorometric method. Anticancer Res 29: 2173-2177, 2009.
-
(2009)
Anticancer Res
, vol.29
, pp. 2173-2177
-
-
Spengler, G.1
Viveiros, M.2
Martins, M.3
Rodrigues, L.4
Martins, A.5
Molnar, J.6
Couto, I.7
Amaral, L.8
-
34
-
-
0013508682
-
A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
-
Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutherford AV and Willingham MC: A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc Natl Acad Sci USA 85: 4486-4490, 1988.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4486-4490
-
-
Pastan, I.1
Gottesman, M.M.2
Ueda, K.3
Lovelace, E.4
Rutherford, A.V.5
Willingham, M.C.6
-
35
-
-
0025861828
-
Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection
-
Choi K, Frommel TO, Stern RK, Perez CF, Kriegler M, Tsuruo T and Roninson IB: Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection. Proc Natl Acad Sci USA 88: 7386-7390, 1991. (Pubitemid 21915156)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.16
, pp. 7386-7390
-
-
Choi, K.1
Frommel, T.O.2
Stern, R.K.3
Perez, C.F.4
Kriegler, M.5
Tsuruo, T.6
Roninson, I.B.7
-
36
-
-
0037512451
-
Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S. aureus and Promotes immune modulation
-
DOI 10.1002/ptr.1314
-
Ordway D, Hohmann J, Viveiros M, Viveiros A, Molnar J, Leandro C, Arroz MJ, Gracio MA and Amaral L: Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S. aureus and promotes immune modulation. Phytother Res 17: 512-519, 2003. (Pubitemid 36605904)
-
(2003)
Phytotherapy Research
, vol.17
, Issue.5
, pp. 512-519
-
-
Ordway, D.1
Hohmann, J.2
Viveiros, M.3
Viveiros, A.4
Molnar, J.5
Leandro, C.6
Arroz, M.J.7
Amelia, M.8
Amaral, G.L.9
-
37
-
-
0036765396
-
Interaction between various resistance modifiers and apoptosis inducer 12H-benzo[a]phenothiazine
-
Mucsi I, Varga A, Kawase M, Motohashi N and Molnar J: Interaction between various resistance modifiers and apoptosis inducer 12H-benzo[alpha] phenothiazine. Anticancer Res 22(5): 2833-2836, 2002. (Pubitemid 36069321)
-
(2002)
Anticancer Research
, vol.22
, Issue.5
, pp. 2833-2836
-
-
Mucsi, I.1
Varga, A.2
Kawase, M.3
Motohashi, N.4
Molnar, J.5
|