Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions

Carcinogenesis

Volumn 25, Issue 5, 2004, Pages 703-712

  Wenzel, Uwe ^a   Nickel, Alexander ^a   Kuntz, Sabine ^a   Daniel, Hannelore ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; ASCORBIC ACID; CAMPTOTHECIN; CASPASE 3; FLAVONE; FLAVONOID; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CANCER CELL; CANCER CHEMOTHERAPY; CELL MEMBRANE; CELL NUCLEUS; CELL STRAIN HT29; CHROMATIN CONDENSATION; COLON CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENCY; DRUG SENSITIVITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; MITOCHONDRION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCAVENGING SYSTEM; WESTERN BLOTTING;

ANTIOXIDANTS; APOPTOSIS; ASCORBIC ACID; BCL-X PROTEIN; CAMPTOTHECIN; CASPASE 3; CASPASES; COLONIC NEOPLASMS; DOWN-REGULATION; FLAVONOIDS; FREE RADICAL SCAVENGERS; HT29 CELLS; HUMANS; HYDROXYL RADICAL; IMMUNOBLOTTING; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDES;

EID: 2442501565     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh079     Document Type: Article

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