Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells

Cancer Biology and Therapy

Volumn 6, Issue 11, 2007, Pages 1794-1799

  Cai, Yujun ^a   Lu, Jinjian ^a   Miao, Zehong ^a   Lin, Liping ^a   Ding, Jian ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

DNA double strand breaks; Multidrug resistant; N acetyl cysteine; P glycoprotein; Reactive oxygen species; Salvicine; Vitamin C

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; ASCORBIC ACID; CATALASE; DOXORUBICIN; ETOPOSIDE; GLUTATHIONE; GLYCOPROTEIN P; HYDROGEN PEROXIDE; PROTEIN C JUN; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SALVICINE; SCAVENGER; STRESS ACTIVATED PROTEIN KINASE; THIOL GROUP;

APOPTOSIS; ARTICLE; CELL KILLING; CHEMOSENSITIVITY; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MULTIDRUG RESISTANCE; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION;

EID: 42549144022     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.6.11.4860     Document Type: Article

References (31)