Inhibit multidrug resistance and induce apoptosis by using glycocholic acid and epirubicin

European Journal of Pharmaceutical Sciences

Volumn 35, Issue 1-2, 2008, Pages 52-67

  Lo, Y L ^a   Ho, C T ^b   Tsai, F L ^c  

^a NATIONAL UNIVERSITY OF TAINAN   (Taiwan)

^b SHIH CHIEN UNIVERSITY   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Apoptosis; Epirubicin; Glycocholic acid; Multidrug resistance

Indexed keywords

BILE ACID; CASPASE 3; CASPASE 9; DAUNORUBICIN; EPIRUBICIN; GLYCOCHOLIC ACID; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; RIFAMPICIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CELL GROWTH; CELL LINE; CHEMOSENSITIVITY; CHEMOTHERAPY; COLON ADENOCARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG EFFICACY; DRUG FORMULATION; DRUG INHIBITION; DRUG MECHANISM; ENZYME INHIBITION; GENE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MDR1 GENE; MITOCHONDRION; MULTIDRUG RESISTANCE; NONHUMAN; NONPUMP RESISTANCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PUMP RESISTANCE; RAT; SMALL INTESTINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CACO-2 CELLS; CELL PROLIFERATION; CHROMATIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA, NEOPLASM; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EPIRUBICIN; FLOW CYTOMETRY; GLYCOCHOLIC ACID; HUMANS; INTESTINES; LUCIFERASES; MALE; MICROSCOPY, FLUORESCENCE; P-GLYCOPROTEINS; PLASMIDS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 48849098124     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.06.003     Document Type: Article

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