-
1
-
-
34247186263
-
Molecular scanning of interleukin-21 gene and genetic susceptibility to type 1 diabetes
-
Asano K., Ikegami H., Fujisawa T., Nishino M., Nojima K., Kawabata Y., Noso S., Hiromine Y., Fukai A., Ogihara T. Molecular scanning of interleukin-21 gene and genetic susceptibility to type 1 diabetes. Hum. Immunol. 2007, 68:384-391.
-
(2007)
Hum. Immunol.
, vol.68
, pp. 384-391
-
-
Asano, K.1
Ikegami, H.2
Fujisawa, T.3
Nishino, M.4
Nojima, K.5
Kawabata, Y.6
Noso, S.7
Hiromine, Y.8
Fukai, A.9
Ogihara, T.10
-
2
-
-
29144434113
-
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
-
Bafica A., Scanga C.A., Feng C.G., Leifer C., Cheever A., Sher A. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J. Exp. Med. 2005, 202:1715-1724.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1715-1724
-
-
Bafica, A.1
Scanga, C.A.2
Feng, C.G.3
Leifer, C.4
Cheever, A.5
Sher, A.6
-
3
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
Betts M.R., Brenchley J.M., Price D.A., De Rosa S.C., Douek D.C., Roederer M., Koup R.A. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J. Immunol. Methods 2003, 281:65-78.
-
(2003)
J. Immunol. Methods
, vol.281
, pp. 65-78
-
-
Betts, M.R.1
Brenchley, J.M.2
Price, D.A.3
De Rosa, S.C.4
Douek, D.C.5
Roederer, M.6
Koup, R.A.7
-
4
-
-
33750833099
-
Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells
-
Brode S., Raine T., Zaccone P., Cooke A. Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells. J. Immunol. 2006, 177:6603-6612.
-
(2006)
J. Immunol.
, vol.177
, pp. 6603-6612
-
-
Brode, S.1
Raine, T.2
Zaccone, P.3
Cooke, A.4
-
5
-
-
27144557584
-
A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles
-
Chattopadhyay P.K., Yu J., Roederer M. A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles. Nat. Med. 2005, 11:1113-1117.
-
(2005)
Nat. Med.
, vol.11
, pp. 1113-1117
-
-
Chattopadhyay, P.K.1
Yu, J.2
Roederer, M.3
-
6
-
-
0346366978
-
Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease
-
Christen U., McGavern D.B., Luster A.D., von Herrath M.G., Oldstone M.B. Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease. J. Immunol. 2003, 171:6838-6845.
-
(2003)
J. Immunol.
, vol.171
, pp. 6838-6845
-
-
Christen, U.1
McGavern, D.B.2
Luster, A.D.3
von Herrath, M.G.4
Oldstone, M.B.5
-
7
-
-
45949090105
-
Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21
-
Clough L.E., Wang C.J., Schmidt E.M., Booth G., Hou T.Z., Ryan G.A., Walker L.S. Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21. J. Immunol. 2008, 180:5393-5401.
-
(2008)
J. Immunol.
, vol.180
, pp. 5393-5401
-
-
Clough, L.E.1
Wang, C.J.2
Schmidt, E.M.3
Booth, G.4
Hou, T.Z.5
Ryan, G.A.6
Walker, L.S.7
-
8
-
-
52349088182
-
IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms
-
Datta S., Sarvetnick N.E. IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms. PLoS ONE 2008, 3:e3118.
-
(2008)
PLoS ONE
, vol.3
-
-
Datta, S.1
Sarvetnick, N.E.2
-
9
-
-
15144356187
-
Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene
-
Denny P., Lord C.J., Hill N.J., Goy J.V., Levy E.R., Podolin P.L., Peterson L.B., Wicker L.S., Todd J.A., Lyons P.A. Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene. Diabetes 1997, 46:695-700.
-
(1997)
Diabetes
, vol.46
, pp. 695-700
-
-
Denny, P.1
Lord, C.J.2
Hill, N.J.3
Goy, J.V.4
Levy, E.R.5
Podolin, P.L.6
Peterson, L.B.7
Wicker, L.S.8
Todd, J.A.9
Lyons, P.A.10
-
10
-
-
33947394423
-
Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells
-
Dooms H., Wolslegel K., Lin P., Abbas A.K. Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells. J. Exp. Med. 2007, 204:547-557.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 547-557
-
-
Dooms, H.1
Wolslegel, K.2
Lin, P.3
Abbas, A.K.4
-
11
-
-
67649217469
-
IL-21 is required to control chronic viral infection
-
Elsaesser H., Sauer K., Brooks D.G. IL-21 is required to control chronic viral infection. Science 2009, 324:1569-1572.
-
(2009)
Science
, vol.324
, pp. 1569-1572
-
-
Elsaesser, H.1
Sauer, K.2
Brooks, D.G.3
-
12
-
-
0037343158
-
A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse
-
Eshima K., Mora C., Wong F.S., Green E.A., Grewal I.S., Flavell R.A. A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse. Int. Immunol. 2003, 15:351-357.
-
(2003)
Int. Immunol.
, vol.15
, pp. 351-357
-
-
Eshima, K.1
Mora, C.2
Wong, F.S.3
Green, E.A.4
Grewal, I.S.5
Flavell, R.A.6
-
13
-
-
67649234772
-
IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
-
Fröhlich A., Kisielow J., Schmitz I., Freigang S., Shamshiev A.T., Weber J., Marsland B.J., Oxenius A., Kopf M. IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 2009, 324:1576-1580.
-
(2009)
Science
, vol.324
, pp. 1576-1580
-
-
Fröhlich, A.1
Kisielow, J.2
Schmitz, I.3
Freigang, S.4
Shamshiev, A.T.5
Weber, J.6
Marsland, B.J.7
Oxenius, A.8
Kopf, M.9
-
14
-
-
0036201121
-
CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells
-
Homann D., Jahreis A., Wolfe T., Hughes A., Coon B., van Stipdonk M.J., Prilliman K.R., Schoenberger S.P., von Herrath M.G. CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells. Immunity 2002, 16:403-415.
-
(2002)
Immunity
, vol.16
, pp. 403-415
-
-
Homann, D.1
Jahreis, A.2
Wolfe, T.3
Hughes, A.4
Coon, B.5
van Stipdonk, M.J.6
Prilliman, K.R.7
Schoenberger, S.P.8
von Herrath, M.G.9
-
15
-
-
0037456367
-
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
-
Janssen E.M., Lemmens E.E., Wolfe T., Christen U., von Herrath M.G., Schoenberger S.P. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature 2003, 421:852-856.
-
(2003)
Nature
, vol.421
, pp. 852-856
-
-
Janssen, E.M.1
Lemmens, E.E.2
Wolfe, T.3
Christen, U.4
von Herrath, M.G.5
Schoenberger, S.P.6
-
16
-
-
61749085092
-
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice
-
Jin H., Oyoshi M.K., Le Y., Bianchi T., Koduru S., Mathias C.B., Kumar L., Le Bras S., Young D., Collins M., et al. IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. J. Clin. Invest. 2009, 119:47-60.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 47-60
-
-
Jin, H.1
Oyoshi, M.K.2
Le, Y.3
Bianchi, T.4
Koduru, S.5
Mathias, C.B.6
Kumar, L.7
Le Bras, S.8
Young, D.9
Collins, M.10
-
17
-
-
0025987029
-
Low dose streptozotocin causes stimulation of the immune system and of anti-islet cytotoxicity in mice
-
Kantwerk-Funke G., Burkart V., Kolb H. Low dose streptozotocin causes stimulation of the immune system and of anti-islet cytotoxicity in mice. Clin. Exp. Immunol. 1991, 86:266-270.
-
(1991)
Clin. Exp. Immunol.
, vol.86
, pp. 266-270
-
-
Kantwerk-Funke, G.1
Burkart, V.2
Kolb, H.3
-
18
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King C., Ilic A., Koelsch K., Sarvetnick N. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 2004, 117:265-277.
-
(2004)
Cell
, vol.117
, pp. 265-277
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
19
-
-
0029812040
-
Constitutive class I-restricted exogenous presentation of self antigens in vivo
-
Kurts C., Heath W.R., Carbone F.R., Allison J., Miller J.F., Kosaka H. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J. Exp. Med. 1996, 184:923-930.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 923-930
-
-
Kurts, C.1
Heath, W.R.2
Carbone, F.R.3
Allison, J.4
Miller, J.F.5
Kosaka, H.6
-
20
-
-
34047178898
-
Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice
-
Martinic M.M., Juedes A.E., Bresson D., Homann D., Skak K., Huber C., Ling E., Ejrnaes M., Wolfe T., Togher L., et al. Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice. Diabetes 2007, 56:1059-1068.
-
(2007)
Diabetes
, vol.56
, pp. 1059-1068
-
-
Martinic, M.M.1
Juedes, A.E.2
Bresson, D.3
Homann, D.4
Skak, K.5
Huber, C.6
Ling, E.7
Ejrnaes, M.8
Wolfe, T.9
Togher, L.10
-
21
-
-
0023905731
-
Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice
-
Miller B.J., Appel M.C., O'Neil J.J., Wicker L.S. Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice. J. Immunol. 1988, 140:52-58.
-
(1988)
J. Immunol.
, vol.140
, pp. 52-58
-
-
Miller, B.J.1
Appel, M.C.2
O'Neil, J.J.3
Wicker, L.S.4
-
22
-
-
4143096772
-
CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions
-
Ohl L., Mohaupt M., Czeloth N., Hintzen G., Kiafard Z., Zwirner J., Blankenstein T., Henning G., Förster R. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 2004, 21:279-288.
-
(2004)
Immunity
, vol.21
, pp. 279-288
-
-
Ohl, L.1
Mohaupt, M.2
Czeloth, N.3
Hintzen, G.4
Kiafard, Z.5
Zwirner, J.6
Blankenstein, T.7
Henning, G.8
Förster, R.9
-
23
-
-
2542476167
-
CD40/CD154 interactions at the interface of tolerance and immunity
-
Quezada S.A., Jarvinen L.Z., Lind E.F., Noelle R.J. CD40/CD154 interactions at the interface of tolerance and immunity. Annu. Rev. Immunol. 2004, 22:307-328.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 307-328
-
-
Quezada, S.A.1
Jarvinen, L.Z.2
Lind, E.F.3
Noelle, R.J.4
-
24
-
-
67649876115
-
New insights into the regulation of T cells by gamma(c) family cytokines
-
Rochman Y., Spolski R., Leonard W.J. New insights into the regulation of T cells by gamma(c) family cytokines. Nat. Rev. Immunol. 2009, 9:480-490.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 480-490
-
-
Rochman, Y.1
Spolski, R.2
Leonard, W.J.3
-
25
-
-
38449111402
-
The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
-
Saxena V., Ondr J.K., Magnusen A.F., Munn D.H., Katz J.D. The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J. Immunol. 2007, 179:5041-5053.
-
(2007)
J. Immunol.
, vol.179
, pp. 5041-5053
-
-
Saxena, V.1
Ondr, J.K.2
Magnusen, A.F.3
Munn, D.H.4
Katz, J.D.5
-
26
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
Schoenberger S.P., Toes R.E., van der Voort E.I., Offringa R., Melief C.J. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998, 393:480-483.
-
(1998)
Nature
, vol.393
, pp. 480-483
-
-
Schoenberger, S.P.1
Toes, R.E.2
van der Voort, E.I.3
Offringa, R.4
Melief, C.J.5
-
27
-
-
42649134105
-
Interleukin-21: basic biology and implications for cancer and autoimmunity
-
Spolski R., Leonard W.J. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 2008, 26:57-79.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 57-79
-
-
Spolski, R.1
Leonard, W.J.2
-
28
-
-
52949091915
-
IL-21 signaling is critical for the development of type I diabetes in the NOD mouse
-
Spolski R., Kashyap M., Robinson C., Yu Z., Leonard W.J. IL-21 signaling is critical for the development of type I diabetes in the NOD mouse. Proc. Natl. Acad. Sci. USA 2008, 105:14028-14033.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14028-14033
-
-
Spolski, R.1
Kashyap, M.2
Robinson, C.3
Yu, Z.4
Leonard, W.J.5
-
29
-
-
65549165290
-
Interleukin-21 is required for the development of type 1 diabetes in NOD mice
-
Sutherland A.P.R., Van Belle T., Wurster A.L., Suto A., Michaud M., Zhang D., Grusby M.J., von Herrath M. Interleukin-21 is required for the development of type 1 diabetes in NOD mice. Diabetes 2009, 58:1144-1155.
-
(2009)
Diabetes
, vol.58
, pp. 1144-1155
-
-
Sutherland, A.P.R.1
Van Belle, T.2
Wurster, A.L.3
Suto, A.4
Michaud, M.5
Zhang, D.6
Grusby, M.J.7
von Herrath, M.8
-
30
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
Genetics of Type 1 Diabetes in Finland, Wellcome Trust Case Control ConsortiumWellcome Trust Case Control Consortium
-
Todd J.A., Walker N.M., Cooper J.D., Smyth D.J., Downes K., Plagnol V., Bailey R., Nejentsev S., Field S.F., Payne F., et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat. Genet. 2007, 39:857-864. Genetics of Type 1 Diabetes in Finland, Wellcome Trust Case Control ConsortiumWellcome Trust Case Control Consortium.
-
(2007)
Nat. Genet.
, vol.39
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
Plagnol, V.6
Bailey, R.7
Nejentsev, S.8
Field, S.F.9
Payne, F.10
-
31
-
-
0345448056
-
Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model
-
Turley S., Poirot L., Hattori M., Benoist C., Mathis D. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J. Exp. Med. 2003, 198:1527-1537.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1527-1537
-
-
Turley, S.1
Poirot, L.2
Hattori, M.3
Benoist, C.4
Mathis, D.5
-
32
-
-
77952242738
-
Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment
-
Van Belle T.L., Juntti T., Liao J., von Herrath M.G. Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment. J. Autoimmun. 2010, 34:445-452.
-
(2010)
J. Autoimmun.
, vol.34
, pp. 445-452
-
-
Van Belle, T.L.1
Juntti, T.2
Liao, J.3
von Herrath, M.G.4
-
33
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies
-
Van Belle T.L., Coppieters K.T., von Herrath M.G. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol. Rev. 2011, 91:79-118.
-
(2011)
Physiol. Rev.
, vol.91
, pp. 79-118
-
-
Van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
34
-
-
0031569514
-
Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor
-
Van Parijs L., Biuckians A., Ibragimov A., Alt F.W., Willerford D.M., Abbas A.K. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. J. Immunol. 1997, 158:3738-3745.
-
(1997)
J. Immunol.
, vol.158
, pp. 3738-3745
-
-
Van Parijs, L.1
Biuckians, A.2
Ibragimov, A.3
Alt, F.W.4
Willerford, D.M.5
Abbas, A.K.6
-
35
-
-
0035177431
-
Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
-
Vermaelen K.Y., Carro-Muino I., Lambrecht B.N., Pauwels R.A. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J. Exp. Med. 2001, 193:51-60.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 51-60
-
-
Vermaelen, K.Y.1
Carro-Muino, I.2
Lambrecht, B.N.3
Pauwels, R.A.4
-
36
-
-
0028446546
-
How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model
-
von Herrath M.G., Dockter J., Oldstone M.B. How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity 1994, 1:231-242.
-
(1994)
Immunity
, vol.1
, pp. 231-242
-
-
von Herrath, M.G.1
Dockter, J.2
Oldstone, M.B.3
-
37
-
-
67649203681
-
A vital role for interleukin-21 in the control of a chronic viral infection
-
Yi J.S., Du M., Zajac A.J. A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009, 324:1572-1576.
-
(2009)
Science
, vol.324
, pp. 1572-1576
-
-
Yi, J.S.1
Du, M.2
Zajac, A.J.3
|