-
1
-
-
45749154576
-
Primary hyperparathyroidism and the skeleton
-
doi:10.1111/j.1365-2265.2007.03162.x
-
Mosekilde L. Primary hyperparathyroidism and the skeleton. Clinical Endocrinology 2008 69 1-19. (doi:10.1111/j.1365-2265.2007.03162.x)
-
(2008)
Clinical Endocrinology
, vol.69
, pp. 1-19
-
-
Mosekilde, L.1
-
2
-
-
1642444847
-
PTH Differentially Regulates Expression of RANKL and OPG
-
DOI 10.1359/JBMR.0301226
-
Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD & Nissenson RA. PTH differentially regulates expression of RANKL and OPG. Journal of Bone and Mineral Research 2004 19 235-244. (doi:10.1359/JBMR.0301226) (Pubitemid 38116737)
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, Issue.2
, pp. 235-244
-
-
Huang, J.C.1
Sakata, T.2
Pfleger, L.L.3
Bencsik, M.4
Halloran, B.P.5
Bikle, D.D.6
Nissenson, R.A.7
-
3
-
-
0033305046
-
Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation
-
doi:10.1210/en.140.8.3552
-
Lee SK & Lorenzo JA. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 1999 140 3552-3561. (doi:10.1210/en.140.8.3552)
-
(1999)
Endocrinology
, vol.140
, pp. 3552-3561
-
-
Lee, S.K.1
Lorenzo, J.A.2
-
4
-
-
0037405048
-
Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone
-
DOI 10.1002/jcb.10490
-
Locklin RM, Khosla S, Turner RT & Riggs BL. Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone. Journal of Cellular Biochemistry 2003 89 180-190. (doi:10.1002/jcb. 10490) (Pubitemid 36459108)
-
(2003)
Journal of Cellular Biochemistry
, vol.89
, Issue.1
, pp. 180-190
-
-
Locklin, R.M.1
Khosla, S.2
Turner, R.T.3
Riggs, B.L.4
-
5
-
-
0034878897
-
Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation
-
doi:10.1210/en.142.9.4047
-
Ma YL, Cain RL, Halladay DL, Yang X, Zeng Q, Miles RR, Chandrasekhar S, Martin TJ & Onyia JE. Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. Endocrinology 2001 142 4047-4054. (doi:10.1210/en.142.9.4047)
-
(2001)
Endocrinology
, vol.142
, pp. 4047-4054
-
-
Ma, Y.L.1
Cain, R.L.2
Halladay, D.L.3
Yang, X.4
Zeng, Q.5
Miles, R.R.6
Chandrasekhar, S.7
Martin, T.J.8
Onyia, J.E.9
-
6
-
-
26844521277
-
Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
-
doi:10.1210/en.2005-0239
-
Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, O'Brien CA, Manolagas SC & Jilka RL. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 2005 146 4577-4583. (doi:10.1210/en.2005- 0239)
-
(2005)
Endocrinology
, vol.146
, pp. 4577-4583
-
-
Bellido, T.1
Ali, A.A.2
Gubrij, I.3
Plotkin, L.I.4
Fu, Q.5
O'Brien, C.A.6
Manolagas, S.C.7
Jilka, R.L.8
-
7
-
-
21844467220
-
SOST is a target gene for PTH in bone
-
DOI 10.1016/j.bone.2005.03.018, PII S8756328205001171
-
Keller H & Kneissel M. SOST is a target gene for PTH in bone. Bone 2005 37 148-158. (doi:10.1016/j.bone.2005.03.018) (Pubitemid 40962421)
-
(2005)
Bone
, vol.37
, Issue.2
, pp. 148-158
-
-
Keller, H.1
Kneissel, M.2
-
8
-
-
51449111663
-
Control of bone mass and remodeling by PTH receptor signaling in osteocytes
-
doi:10.1371/journal.pone.0002942
-
O'Brien CA, Plotkin LI, Galli C, Goellner JJ, Gortazar AR, Allen MR, Robling AG, Bouxsein M, Schipani E, Turner CH, Jilka RL, Weinstein RS, Manolagas SC & Bellido T. Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS ONE 2008 3 e2942. (doi:10.1371/journal.pone. 0002942)
-
(2008)
PLoS ONE
, vol.3
-
-
O'Brien, C.A.1
Plotkin, L.I.2
Galli, C.3
Goellner, J.J.4
Gortazar, A.R.5
Allen, M.R.6
Robling, A.G.7
Bouxsein, M.8
Schipani, E.9
Turner, C.H.10
Jilka, R.L.11
Weinstein, R.S.12
Manolagas, S.C.13
Bellido, T.14
-
9
-
-
34547109349
-
Effects of intermittent parathyroid hormone (PTH) administration on SOST mRNA and protein in rat bone
-
doi:10.1007/s10735-007-9096-3
-
Silvestrini G, Ballanti P, Leopizzi M, Sebastiani M, Berni S, Di Vito M & Bonucci E. Effects of intermittent parathyroid hormone (PTH) administration on SOST mRNA and protein in rat bone. Journal of Molecular Histology 2007 38 261-269. (doi:10.1007/s10735-007-9096-3)
-
(2007)
Journal of Molecular Histology
, vol.38
, pp. 261-269
-
-
Silvestrini, G.1
Ballanti, P.2
Leopizzi, M.3
Sebastiani, M.4
Berni, S.5
Di Vito, M.6
Bonucci, E.7
-
10
-
-
12144286871
-
Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist
-
doi:10.1084/jem.20031454
-
van Bezooijen RL, Roelen BA, Visser A, van der Wee-Pals L, de Wilt E, Karperien M, Hamersma H, Papapoulos SE, ten Dijke P & Löwik CW. Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist. Journal of Experimental Medicine 2004 199 805-814. (doi:10.1084/jem.20031454)
-
(2004)
Journal of Experimental Medicine
, vol.199
, pp. 805-814
-
-
Van Bezooijen, R.L.1
Roelen, B.A.2
Visser, A.3
Van Der Wee-Pals, L.4
De Wilt, E.5
Karperien, M.6
Hamersma, H.7
Papapoulos, S.E.8
Ten Dijke, P.9
Löwik, C.W.10
-
11
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
doi:10.1074/jbc.M413274200
-
Li X, Zhang Y, Kang H, Liu W, Liu P, Zhang J, Harris SE & Wu D. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. Journal of Biological Chemistry 2005 280 19883-19887. (doi:10.1074/jbc.M413274200)
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
Liu, W.4
Liu, P.5
Zhang, J.6
Harris, S.E.7
Wu, D.8
-
12
-
-
33846449190
-
Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
-
doi:10.1359/jbmr.060810
-
Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S & Krumlauf R. Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. Journal of Bone and Mineral Research 2006 21 1738-1749. (doi:10.1359/jbmr.060810)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, pp. 1738-1749
-
-
Ellies, D.L.1
Viviano, B.2
McCarthy, J.3
Rey, J.P.4
Itasaki, N.5
Saunders, S.6
Krumlauf, R.7
-
13
-
-
0035282968
-
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
-
doi:10.1093/hmg/10.5.537
-
Balemans W, Ebeling M, Patel N, Van Hul E, Olson P, Dioszegi M, Lacza C, Wuyts W, Van Den Ende J, Willems P, Paes-Alves AF, Hill S, Bueno M, Ramos FJ, Tacconi P, Dikkers FG, Stratakis C, Lindpaintner K, Vickery B, Foernzler D & Van Hul W. Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Human Molecular Genetics 2001 10 537-543. (doi:10.1093/hmg/10.5.537)
-
(2001)
Human Molecular Genetics
, vol.10
, pp. 537-543
-
-
Balemans, W.1
Ebeling, M.2
Patel, N.3
Van Hul, E.4
Olson, P.5
Dioszegi, M.6
Lacza, C.7
Wuyts, W.8
Van Den Ende, J.9
Willems, P.10
Paes-Alves, A.F.11
Hill, S.12
Bueno, M.13
Ramos, F.J.14
Tacconi, P.15
Dikkers, F.G.16
Stratakis, C.17
Lindpaintner, K.18
Vickery, B.19
Foernzler, D.20
Van Hul, W.21
more..
-
14
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
DOI 10.1359/jbmr.080216
-
Li X, Ominsky MS, Niu QT, Sun N, Daugherty B, D 'Agostin D, Kurahara C, Gao Y, Cao J, Gong J, Asuncion F, Barrero M, Warmington K, Dwyer D, Stolina M, Morony S, Sarosi I, Kostenuik PJ, Lacey DL, Simonet WS, Ke HZ & Paszty C. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. Journal of Bone and Mineral Research 2008 23 860-869. (doi:10.1359/jbmr.080216) (Pubitemid 351768804)
-
(2008)
Journal of Bone and Mineral Research
, vol.23
, Issue.6
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.-T.3
Sun, N.4
Daugherty, B.5
D'Agostin, D.6
Kurahara, C.7
Gao, Y.8
Cao, J.9
Gong, J.10
Asuncion, F.11
Barrero, M.12
Warmington, K.13
Dwyer, D.14
Stolina, M.15
Morony, S.16
Sarosi, I.17
Kostenuik, P.J.18
Lacey, D.L.19
Simonet, W.S.20
Hua, Z.K.21
Paszty, C.22
more..
-
15
-
-
77953481395
-
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
-
doi:10.1002/jbmr.14
-
Ominsky MS, Vlasseros F, Jolette J, Smith SY, Stouch B, Doellgast G, Gong J, Gao Y, Cao J, Graham K, Tipton B, Cai J, Deshpande R, Zhou L, Hale MD, Lightwood DJ, Henry AJ, Popplewell AG, Moore AR, Robinson MK, Lacey DL, Simonet WS & Paszty C. Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. Journal of Bone and Mineral Research 2010 25 948-959. (doi:10.1002/jbmr.14)
-
(2010)
Journal of Bone and Mineral Research
, vol.25
, pp. 948-959
-
-
Ominsky, M.S.1
Vlasseros, F.2
Jolette, J.3
Smith, S.Y.4
Stouch, B.5
Doellgast, G.6
Gong, J.7
Gao, Y.8
Cao, J.9
Graham, K.10
Tipton, B.11
Cai, J.12
Deshpande, R.13
Zhou, L.14
Hale, M.D.15
Lightwood, D.J.16
Henry, A.J.17
Popplewell, A.G.18
Moore, A.R.19
Robinson, M.K.20
Lacey, D.L.21
Simonet, W.S.22
Paszty, C.23
more..
-
16
-
-
38849186793
-
Anti-sclerostin antibody increases markers of bone formation in healthy postmenopausal women
-
Padhi D, Stouch B, Jang G, Fang L, Darling M, Glise H, Robinson M, Harris S & Posvar E. Anti-sclerostin antibody increases markers of bone formation in healthy postmenopausal women. Journal of Bone and Mineral Research 2007 22 S37.
-
(2007)
Journal of Bone and Mineral Research
, vol.22
-
-
Padhi, D.1
Stouch, B.2
Jang, G.3
Fang, L.4
Darling, M.5
Glise, H.6
Robinson, M.7
Harris, S.8
Posvar, E.9
-
17
-
-
10744221383
-
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
-
DOI 10.1093/emboj/cdg599
-
Winkler DG, Sutherland MK, Geoghegan JC, Yu C, Hayes T, Skonier JE, Shpektor D, Jonas M, Kovacevich BR, Karen Staehling-Hampton KS, Appleby M, Brunkow ME & Latham JA. Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO Journal 2003 22 6267-6276. (doi:10.1093/emboj/ cdg599) (Pubitemid 37522584)
-
(2003)
EMBO Journal
, vol.22
, Issue.23
, pp. 6267-6276
-
-
Winkler, D.G.1
Sutherland, M.K.2
Geoghegan, J.C.3
Yu, C.4
Hayes, T.5
Skonier, J.E.6
Shpektor, D.7
Jonas, M.8
Kovacevich, B.R.9
Staehling-Hampton, K.10
Appleby, M.11
Brunkow, M.E.12
Latham, J.A.13
-
18
-
-
41949089764
-
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
-
doi:10.1074/jbc.M705092200
-
Robling AG, Niziolek PJ, Baldridge LA, Condon KW, Allen MR, Alam I, Mantila SM, Gluhak-Heinrich J, Bellido TM, Harris SE & Turner CH. Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. Journal of Biological Chemistry 2008 283 5866-5875. (doi:10.1074/jbc.M705092200)
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 5866-5875
-
-
Robling, A.G.1
Niziolek, P.J.2
Baldridge, L.A.3
Condon, K.W.4
Allen, M.R.5
Alam, I.6
Mantila, S.M.7
Gluhak-Heinrich, J.8
Bellido, T.M.9
Harris, S.E.10
Turner, C.H.11
-
19
-
-
77952992328
-
Parathyroid hormone (PTH) induced bone gain is blunted in SOST overexpressing and deficient mice
-
doi:10.1359/jbmr.090730
-
Kramer I, Loots GG, Studer A, Keller H & Kneissel M. Parathyroid hormone (PTH) induced bone gain is blunted in SOST overexpressing and deficient mice. Journal of Bone and Mineral Research 2010 25 178-189. (doi:10.1359/jbmr. 090730)
-
(2010)
Journal of Bone and Mineral Research
, vol.25
, pp. 178-189
-
-
Kramer, I.1
Loots, G.G.2
Studer, A.3
Keller, H.4
Kneissel, M.5
-
20
-
-
77951644377
-
Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women
-
doi:10.1210/jc.2009-2283
-
Mirza FS, Padhi ID, Raisz LG & Lorenzo JA. Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women. Journal of Clinical Endocrinology and Metabolism 2010 95 1991-1997. (doi:10.1210/jc.2009-2283)
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, pp. 1991-1997
-
-
Mirza, F.S.1
Padhi, I.D.2
Raisz, L.G.3
Lorenzo, J.A.4
-
21
-
-
77957853500
-
Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
-
doi:10.1210/jc.2010-0720
-
Drake MT, Srinivasan B, Modder UI, Peterson JM, McCready LK, Riggs BL, Dwyer D, Stolina M, Kostenuik P & Khosla S. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. Journal of Clinical Endocrinology and Metabolism, 2010. (doi:10.1210/jc.2010-0720)
-
(2010)
Journal of Clinical Endocrinology and Metabolism
-
-
Drake, M.T.1
Srinivasan, B.2
Modder, U.I.3
Peterson, J.M.4
McCready, L.K.5
Riggs, B.L.6
Dwyer, D.7
Stolina, M.8
Kostenuik, P.9
Khosla, S.10
-
22
-
-
77957846460
-
Relation of age, gender, and bone mass to circulating sclerostin levels in women and men
-
doi:10.1002/jbmr.217
-
Mödder UI, Hoey KA, Amin S, McCready LK, Achenbach SJ, Lawrence RB, Joseph ML & Khosla S. Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. Journal of Bone and Mineral Research, 2010. (doi:10.1002/jbmr.217)
-
(2010)
Journal of Bone and Mineral Research
-
-
Mödder, U.I.1
Hoey, K.A.2
Amin, S.3
McCready, L.K.4
Achenbach, S.J.5
Lawrence, R.B.6
Joseph, M.L.7
Khosla, S.8
-
23
-
-
67349147522
-
PTH and PTHrP signaling in osteoblasts
-
doi:10.1016/j.cellsig.2009.02.012
-
Datta NS & Abou-Samra AB. PTH and PTHrP signaling in osteoblasts. Cellular Signalling 2009 21 1245-1254. (doi:10.1016/j.cellsig.2009.02.012)
-
(2009)
Cellular Signalling
, vol.21
, pp. 1245-1254
-
-
Datta, N.S.1
Abou-Samra, A.B.2
-
24
-
-
34248577022
-
Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
-
doi:10.1016/j.bone.2007.03.017
-
Jilka RL. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 2007 40 1434-1446. (doi:10.1016/j.bone.2007.03.017)
-
(2007)
Bone
, vol.40
, pp. 1434-1446
-
-
Jilka, R.L.1
|