메뉴 건너뛰기




Volumn 353, Issue 2, 2013, Pages 311-325

The potential of stem cell research for the treatment of neuronal damage in glaucoma

Author keywords

Degeneration; Neuroprotection; Regeneration; Retina; Stem cells

Indexed keywords

ADULT STEM CELL; CELL LOSS; CLOSED ANGLE GLAUCOMA; EMBRYONIC STEM CELL; GLAUCOMA; HUMAN; INTRAOCULAR PRESSURE; MUELLER CELL; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; OPEN ANGLE GLAUCOMA; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RETINA DEGENERATION; RETINA DEVELOPMENT; RETINA GANGLION CELL; REVIEW; STEM CELL RESEARCH; STEM CELL TRANSPLANTATION;

EID: 84880768643     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-013-1646-2     Document Type: Review
Times cited : (18)

References (143)
  • 1
    • 70350214500 scopus 로고    scopus 로고
    • From progenitors to differentiated cells in the vertebrate retina
    • 19575661 1:CAS:528:DC%2BD1MXhsVKisbrO 10.1146/annurev.cellbio.042308. 113259
    • Agathocleous M, Harris WA (2009) From progenitors to differentiated cells in the vertebrate retina. Annu Rev Cell Dev Biol 25:45-69
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 45-69
    • Agathocleous, M.1    Harris, W.A.2
  • 2
    • 84857108227 scopus 로고    scopus 로고
    • The molecular basis of retinal ganglion cell death in glaucoma
    • 22155051 1:CAS:528:DC%2BC38Xis1emu7w%3D 10.1016/j.preteyeres.2011.11.002
    • Almasieh M, Wilson AM, Morquette B, Cueva Vargas JL, Di Polo A (2012) The molecular basis of retinal ganglion cell death in glaucoma. Prog Retin Eye Res 31:152-181
    • (2012) Prog Retin Eye Res , vol.31 , pp. 152-181
    • Almasieh, M.1    Wilson, A.M.2    Morquette, B.3    Cueva Vargas, J.L.4    Di Polo, A.5
  • 4
    • 0034307763 scopus 로고    scopus 로고
    • Live or let die - Retinal ganglion cell death and survival during development and in the lesioned adult CNS
    • 11006465 1:CAS:528:DC%2BD3cXmslKltbs%3D 10.1016/S0166-2236(00)01637-4
    • Bahr M (2000) Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS. Trends Neurosci 23:483-490
    • (2000) Trends Neurosci , vol.23 , pp. 483-490
    • Bahr, M.1
  • 6
    • 41049110191 scopus 로고    scopus 로고
    • Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice
    • 18329018 1:CAS:528:DC%2BD1cXktFCrsLk%3D 10.1016/j.exer.2008.01.018
    • Bartsch U, Oriyakhel W, Kenna PF, Linke S, Richard G, Petrowitz B, Humphries P, Farrar GJ, Ader M (2008) Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice. Exp Eye Res 86:691-700
    • (2008) Exp Eye Res , vol.86 , pp. 691-700
    • Bartsch, U.1    Oriyakhel, W.2    Kenna, P.F.3    Linke, S.4    Richard, G.5    Petrowitz, B.6    Humphries, P.7    Farrar, G.J.8    Ader, M.9
  • 7
    • 84867839464 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: The new patient?
    • 23034453 10.1038/nrm3448 1:CAS:528:DC%2BC38XhsVGjsLzI
    • Bellin M, Marchetto MC, Gage FH, Mummery CL (2012) Induced pluripotent stem cells: the new patient? Nat Rev Mol Cell Biol 13:713-726
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 713-726
    • Bellin, M.1    Marchetto, M.C.2    Gage, F.H.3    Mummery, C.L.4
  • 8
    • 77954621518 scopus 로고    scopus 로고
    • The molecular basis of human retinal and vitreoretinal diseases
    • 20362068 1:CAS:528:DC%2BC3cXos1Cnt78%3D 10.1016/j.preteyeres.2010.03.004
    • Berger W, Kloeckener-Gruissem B, Neidhardt J (2010) The molecular basis of human retinal and vitreoretinal diseases. Prog Retin Eye Res 29:335-375
    • (2010) Prog Retin Eye Res , vol.29 , pp. 335-375
    • Berger, W.1    Kloeckener-Gruissem, B.2    Neidhardt, J.3
  • 9
    • 79961181178 scopus 로고    scopus 로고
    • Regulated reprogramming in the regeneration of sensory receptor cells
    • 21835338 1:CAS:528:DC%2BC3MXhtVajsbfN 10.1016/j.neuron.2011.07.015
    • Bermingham-McDonogh O, Reh TA (2011) Regulated reprogramming in the regeneration of sensory receptor cells. Neuron 71:389-405
    • (2011) Neuron , vol.71 , pp. 389-405
    • Bermingham-Mcdonogh, O.1    Reh, T.A.2
  • 10
    • 84855916176 scopus 로고    scopus 로고
    • Differences between the neurogenic and proliferative abilities of Muller glia with stem cell characteristics and the ciliary epithelium from the adult human eye
    • 21989110 1:CAS:528:DC%2BC3MXhsFegu7bN 10.1016/j.exer.2011.09.015
    • Bhatia B, Jayaram H, Singhal S, Jones MF, Limb GA (2011) Differences between the neurogenic and proliferative abilities of Muller glia with stem cell characteristics and the ciliary epithelium from the adult human eye. Exp Eye Res 93:852-861
    • (2011) Exp Eye Res , vol.93 , pp. 852-861
    • Bhatia, B.1    Jayaram, H.2    Singhal, S.3    Jones, M.F.4    Limb, G.A.5
  • 11
    • 84874322462 scopus 로고    scopus 로고
    • Brief report: Self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors
    • 23132794 1:CAS:528:DC%2BC3sXjvFOhsro%3D 10.1002/stem.1268
    • Boucherie C, Mukherjee S, Henckaerts E, Thrasher AJ, Sowden JC, Ali RR (2013) Brief report: self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors. Stem Cells 31:408-414
    • (2013) Stem Cells , vol.31 , pp. 408-414
    • Boucherie, C.1    Mukherjee, S.2    Henckaerts, E.3    Thrasher, A.J.4    Sowden, J.C.5    Ali, R.R.6
  • 13
    • 70350423565 scopus 로고    scopus 로고
    • Cellular signaling and factors involved in Muller cell gliosis: Neuroprotective and detrimental effects
    • 19660572 1:CAS:528:DC%2BD1MXhtlCmsL3I 10.1016/j.preteyeres.2009.07.001
    • Bringmann A, Iandiev I, Pannicke T, Wurm A, Hollborn M, Wiedemann P, Osborne NN, Reichenbach A (2009) Cellular signaling and factors involved in Muller cell gliosis: neuroprotective and detrimental effects. Prog Retin Eye Res 28:423-451
    • (2009) Prog Retin Eye Res , vol.28 , pp. 423-451
    • Bringmann, A.1    Iandiev, I.2    Pannicke, T.3    Wurm, A.4    Hollborn, M.5    Wiedemann, P.6    Osborne, N.N.7    Reichenbach, A.8
  • 14
    • 84880781756 scopus 로고    scopus 로고
    • Retinal histiogenesis
    • J.C. Besharse D. Bok (eds) Academic Press New York
    • Brzezinski IV JA, Reh TA (2011) Retinal histiogenesis. In: Besharse JC, Bok D (eds) The retina and its disorders. Academic Press, New York, pp 745-752
    • (2011) The Retina and Its Disorders , pp. 745-752
    • Brzezinski, I.V.J.A.1    Reh, T.A.2
  • 15
    • 84862524591 scopus 로고    scopus 로고
    • Genome-wide association studies in the hunt for genes causing primary open-angle glaucoma: A review
    • 22171998 10.1111/j.1442-9071.2011.02744.x
    • Burdon KP (2012) Genome-wide association studies in the hunt for genes causing primary open-angle glaucoma: a review. Clin Experiment Ophthalmol 40:358-363
    • (2012) Clin Experiment Ophthalmol , vol.40 , pp. 358-363
    • Burdon, K.P.1
  • 17
    • 0032965752 scopus 로고    scopus 로고
    • The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates
    • 10072376 1:CAS:528:DyaK1MXhvVWitbs%3D 10.1016/S0959-4388(99)80005-1
    • Cepko CL (1999) The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Curr Opin Neurobiol 9:37-46
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 37-46
    • Cepko, C.L.1
  • 19
    • 84858390754 scopus 로고    scopus 로고
    • Reprogramming cellular identity for regenerative medicine
    • 22424223 1:CAS:528:DC%2BC38Xkt1Gjtbw%3D 10.1016/j.cell.2012.02.031
    • Cherry AB, Daley GQ (2012) Reprogramming cellular identity for regenerative medicine. Cell 148:1110-1122
    • (2012) Cell , vol.148 , pp. 1110-1122
    • Cherry, A.B.1    Daley, G.Q.2
  • 21
    • 0038132019 scopus 로고    scopus 로고
    • Ophthalmic drug discovery
    • 12776220 1:CAS:528:DC%2BD3sXktFOhu78%3D 10.1038/nrd1106
    • Clark AF, Yorio T (2003) Ophthalmic drug discovery. Nat Rev Drug Discov 2:448-459
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 448-459
    • Clark, A.F.1    Yorio, T.2
  • 27
    • 84875963894 scopus 로고    scopus 로고
    • Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs
    • 23561441 1:CAS:528:DC%2BC3sXls1ektrk%3D 10.1016/j.stem.2013.03.006
    • Ding Q, Regan SN, Xia Y, Oostrom LA, Cowan CA, Musunuru K (2013b) Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. Cell Stem Cell 12:393-394
    • (2013) Cell Stem Cell , vol.12 , pp. 393-394
    • Ding, Q.1    Regan, S.N.2    Xia, Y.3    Oostrom, L.A.4    Cowan, C.A.5    Musunuru, K.6
  • 29
    • 80054042196 scopus 로고    scopus 로고
    • Increased integration of transplanted CD73-positive photoreceptor precursors into adult mouse retina
    • 21743009 1:CAS:528:DC%2BC3MXhtlWrsr7L 10.1167/iovs.11-7399
    • Eberle D, Schubert S, Postel K, Corbeil D, Ader M (2011) Increased integration of transplanted CD73-positive photoreceptor precursors into adult mouse retina. Invest Ophthalmol Vis Sci 52:6462-6471
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 6462-6471
    • Eberle, D.1    Schubert, S.2    Postel, K.3    Corbeil, D.4    Ader, M.5
  • 30
    • 84867028244 scopus 로고    scopus 로고
    • Outer segment formation of transplanted photoreceptor precursor cells
    • 23029471 1:CAS:528:DC%2BC38XhsFShsL%2FI 10.1371/journal.pone.0046305
    • Eberle D, Kurth T, Santos-Ferreira T, Wilson J, Corbeil D, Ader M (2012) Outer segment formation of transplanted photoreceptor precursor cells. PLoS One 7:e46305
    • (2012) PLoS One , vol.7 , pp. 46305
    • Eberle, D.1    Kurth, T.2    Santos-Ferreira, T.3    Wilson, J.4    Corbeil, D.5    Ader, M.6
  • 31
    • 84860233475 scopus 로고    scopus 로고
    • Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues
    • 1:CAS:528:DC%2BC3MXhs1eisbrI 10.1038/nprot.2011.429
    • Eiraku M, Sasai Y (2012) Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues. Nat Protoc 7:69-79
    • (2012) Nat Protoc , vol.7 , pp. 69-79
    • Eiraku, M.1    Sasai, Y.2
  • 33
    • 33644959278 scopus 로고    scopus 로고
    • Gene mapping for primary open angle glaucoma
    • 16332362 1:CAS:528:DC%2BD28Xis1Wju7g%3D 10.1016/j.clinbiochem.2005.11.001
    • Fan BJ, Wang DY, Lam DS, Pang CP (2006) Gene mapping for primary open angle glaucoma. Clin Biochem 39:249-258
    • (2006) Clin Biochem , vol.39 , pp. 249-258
    • Fan, B.J.1    Wang, D.Y.2    Lam, D.S.3    Pang, C.P.4
  • 34
    • 0035157638 scopus 로고    scopus 로고
    • Apoptosis, neuroprotection, and retinal ganglion cell death: An overview
    • 11198138 1:STN:280:DC%2BD3M7jvFGhsw%3D%3D 10.1097/00004397-200101000- 00011
    • Farkas RH, Grosskreutz CL (2001) Apoptosis, neuroprotection, and retinal ganglion cell death: an overview. Int Ophthalmol Clin 41:111-130
    • (2001) Int Ophthalmol Clin , vol.41 , pp. 111-130
    • Farkas, R.H.1    Grosskreutz, C.L.2
  • 35
    • 33847141503 scopus 로고    scopus 로고
    • Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish
    • 17301179 1:CAS:528:DC%2BD2sXitl2nsL8%3D 10.1523/JNEUROSCI.5317-06.2007
    • Fimbel SM, Montgomery JE, Burket CT, Hyde DR (2007) Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish. J Neurosci 27:1712-1724
    • (2007) J Neurosci , vol.27 , pp. 1712-1724
    • Fimbel, S.M.1    Montgomery, J.E.2    Burket, C.T.3    Hyde, D.R.4
  • 37
    • 84875966999 scopus 로고    scopus 로고
    • Cell-based therapeutics: The next pillar of medicine
    • 23552369 1:CAS:528:DC%2BC3sXmsFGht7c%3D 10.1126/scitranslmed.3005568
    • Fischbach MA, Bluestone JA, Lim WA (2013) Cell-based therapeutics: the next pillar of medicine. Sci Transl Med 5:179ps7
    • (2013) Sci Transl Med , vol.5
    • Fischbach, M.A.1    Bluestone, J.A.2    Lim, W.A.3
  • 38
    • 10944237890 scopus 로고    scopus 로고
    • Neural regeneration in the chick retina
    • 15610972 10.1016/j.preteyeres.2004.07.003
    • Fischer AJ (2005) Neural regeneration in the chick retina. Prog Retin Eye Res 24:161-182
    • (2005) Prog Retin Eye Res , vol.24 , pp. 161-182
    • Fischer, A.J.1
  • 39
    • 84863230548 scopus 로고    scopus 로고
    • Current concepts on primary open-angle glaucoma genetics: A contribution to disease pathophysiology and future treatment
    • 1:CAS:528:DC%2BC38Xjs1Cru7g%3D 10.1038/eye.2011.309
    • Gemenetzi M, Yang Y, Lotery AJ (2012) Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment. Eye (Lond) 26:355-369
    • (2012) Eye (Lond) , vol.26 , pp. 355-369
    • Gemenetzi, M.1    Yang, Y.2    Lotery, A.J.3
  • 40
    • 79952142756 scopus 로고    scopus 로고
    • Adult human Muller glia cells are a highly efficient source of rod photoreceptors
    • 21732491 1:CAS:528:DC%2BC3MXks1altL0%3D 10.1002/stem.579
    • Giannelli SG, Demontis GC, Pertile G, Rama P, Broccoli V (2011) Adult human Muller glia cells are a highly efficient source of rod photoreceptors. Stem Cells 29:344-356
    • (2011) Stem Cells , vol.29 , pp. 344-356
    • Giannelli, S.G.1    Demontis, G.C.2    Pertile, G.3    Rama, P.4    Broccoli, V.5
  • 41
    • 77955335646 scopus 로고    scopus 로고
    • Eye development
    • 20691855 10.1016/S0070-2153(10)90010-0
    • Graw J (2010) Eye development. Curr Top Dev Biol 90:343-386
    • (2010) Curr Top Dev Biol , vol.90 , pp. 343-386
    • Graw, J.1
  • 42
    • 33847034391 scopus 로고    scopus 로고
    • Glaucoma as a neurodegenerative disease
    • 17301611 10.1097/ICU.0b013e3280895aea
    • Gupta N, Yucel YH (2007) Glaucoma as a neurodegenerative disease. Curr Opin Ophthalmol 18:110-114
    • (2007) Curr Opin Ophthalmol , vol.18 , pp. 110-114
    • Gupta, N.1    Yucel, Y.H.2
  • 43
    • 79960877703 scopus 로고    scopus 로고
    • Adult donor rod photoreceptors integrate into the mature mouse retina
    • 21436277 10.1167/iovs.10-6329
    • Gust J, Reh TA (2011) Adult donor rod photoreceptors integrate into the mature mouse retina. Invest Ophthalmol Vis Sci 52:5266-5272
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 5266-5272
    • Gust, J.1    Reh, T.A.2
  • 44
    • 84880263513 scopus 로고    scopus 로고
    • Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration
    • 21304518 10.1038/ncomms1190 1:CAS:528:DC%2BC3MXltF2jsb8%3D
    • Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T (2011) Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration. Nat Commun 2:189
    • (2011) Nat Commun , vol.2 , pp. 189
    • Harada, C.1    Guo, X.2    Namekata, K.3    Kimura, A.4    Nakamura, K.5    Tanaka, K.6    Parada, L.F.7    Harada, T.8
  • 46
    • 79953012366 scopus 로고    scopus 로고
    • Retinal ganglion cell gene therapy and visual system repair
    • 21291357 1:CAS:528:DC%2BC3MXkslSgtLw%3D 10.2174/156652311794940746
    • Hellstrom M, Harvey AR (2011) Retinal ganglion cell gene therapy and visual system repair. Curr Gene Ther 11:116-131
    • (2011) Curr Gene Ther , vol.11 , pp. 116-131
    • Hellstrom, M.1    Harvey, A.R.2
  • 48
    • 80052415551 scopus 로고    scopus 로고
    • Gene targeting in human pluripotent cells
    • 21209393 1:CAS:528:DC%2BC38XnsVOjt7o%3D 10.1101/sqb.2010.75.021
    • Hockemeyer D, Jaenisch R (2010) Gene targeting in human pluripotent cells. Cold Spring Harb Symp Quant Biol 75:201-209
    • (2010) Cold Spring Harb Symp Quant Biol , vol.75 , pp. 201-209
    • Hockemeyer, D.1    Jaenisch, R.2
  • 52
    • 84866442827 scopus 로고    scopus 로고
    • Review: A meta-analysis of GWAS and age-associated diseases
    • 22888763 1:CAS:528:DC%2BC38XhsFCls7%2FI 10.1111/j.1474-9726.2012.00871.x
    • Jeck WR, Siebold AP, Sharpless NE (2012) Review: a meta-analysis of GWAS and age-associated diseases. Aging Cell 11:727-731
    • (2012) Aging Cell , vol.11 , pp. 727-731
    • Jeck, W.R.1    Siebold, A.P.2    Sharpless, N.E.3
  • 53
    • 79951849153 scopus 로고    scopus 로고
    • Modeling retinal degeneration using patient-specific induced pluripotent stem cells
    • 21347327 1:CAS:528:DC%2BC3MXisVeqsLk%3D 10.1371/journal.pone.0017084
    • Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M (2011) Modeling retinal degeneration using patient-specific induced pluripotent stem cells. PLoS One 6:e17084
    • (2011) PLoS One , vol.6 , pp. 17084
    • Jin, Z.B.1    Okamoto, S.2    Osakada, F.3    Homma, K.4    Assawachananont, J.5    Hirami, Y.6    Iwata, T.7    Takahashi, M.8
  • 54
    • 70350144849 scopus 로고    scopus 로고
    • Transplantation prospects for the inner retina
    • 1:STN:280:DC%2BD1MnovFyltQ%3D%3D 10.1038/eye.2008.376
    • Johnson TV, Bull ND, Martin KR (2009) Transplantation prospects for the inner retina. Eye (Lond) 23:1980-1984
    • (2009) Eye (Lond) , vol.23 , pp. 1980-1984
    • Johnson, T.V.1    Bull, N.D.2    Martin, K.R.3
  • 55
    • 84862822079 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells and neurodegenerative disease: Prospects for novel therapies
    • 22357218 1:CAS:528:DC%2BC38XjsVCrsLo%3D 10.1097/WCO.0b013e3283518226
    • Jung YW, Hysolli E, Kim KY, Tanaka Y, Park IH (2012) Human induced pluripotent stem cells and neurodegenerative disease: prospects for novel therapies. Curr Opin Neurol 25:125-130
    • (2012) Curr Opin Neurol , vol.25 , pp. 125-130
    • Jung, Y.W.1    Hysolli, E.2    Kim, K.Y.3    Tanaka, Y.4    Park, I.H.5
  • 56
    • 77950486864 scopus 로고    scopus 로고
    • Regenerative medicine for retinal diseases: Activating endogenous repair mechanisms
    • 20303826 1:CAS:528:DC%2BC3cXksFCiuro%3D 10.1016/j.molmed.2010.02.003
    • Karl MO, Reh TA (2010) Regenerative medicine for retinal diseases: activating endogenous repair mechanisms. Trends Mol Med 16:193-202
    • (2010) Trends Mol Med , vol.16 , pp. 193-202
    • Karl, M.O.1    Reh, T.A.2
  • 57
    • 84867589287 scopus 로고    scopus 로고
    • Studying the generation of regenerated retinal neuron from Muller glia in the mouse eye
    • 22688709 1:CAS:528:DC%2BC3sXkvVyhuw%3D%3D 10.1007/978-1-61779-848-1-15
    • Karl MO, Reh TA (2012) Studying the generation of regenerated retinal neuron from Muller glia in the mouse eye. Methods Mol Biol 884:213-227
    • (2012) Methods Mol Biol , vol.884 , pp. 213-227
    • Karl, M.O.1    Reh, T.A.2
  • 61
    • 84866251939 scopus 로고    scopus 로고
    • Distinct neurogenic potential in the retinal margin and the pars plana of mammalian eye
    • 22973003 1:CAS:528:DC%2BC38XhsVSlsbnP 10.1523/JNEUROSCI.0118-12.2012
    • Kiyama T, Li H, Gupta M, Lin YP, Chuang AZ, Otteson DC, Wang SW (2012) Distinct neurogenic potential in the retinal margin and the pars plana of mammalian eye. J Neurosci 32:12797-12807
    • (2012) J Neurosci , vol.32 , pp. 12797-12807
    • Kiyama, T.1    Li, H.2    Gupta, M.3    Lin, Y.P.4    Chuang, A.Z.5    Otteson, D.C.6    Wang, S.W.7
  • 63
    • 84867600805 scopus 로고    scopus 로고
    • Production and transplantation of retinal cells from human and mouse embryonic stem cells
    • 22688710 10.1007/978-1-61779-848-1-16 1:CAS:528:DC%2BC3sXkvVygsw%3D%3D
    • La Torre A, Lamba DA, Jayabalu A, Reh TA (2012) Production and transplantation of retinal cells from human and mouse embryonic stem cells. Methods Mol Biol 884:229-246
    • (2012) Methods Mol Biol , vol.884 , pp. 229-246
    • La Torre, A.1    Lamba, D.A.2    Jayabalu, A.3    Reh, T.A.4
  • 64
    • 33748086466 scopus 로고    scopus 로고
    • Efficient generation of retinal progenitor cells from human embryonic stem cells
    • 16908856 1:CAS:528:DC%2BD28XptVymsrw%3D 10.1073/pnas.0601990103
    • Lamba DA, Karl MO, Ware CB, Reh TA (2006) Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci USA 103:12769-12774
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12769-12774
    • Lamba, D.A.1    Karl, M.O.2    Ware, C.B.3    Reh, T.A.4
  • 65
    • 58049200677 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice
    • 19128794 1:CAS:528:DC%2BD1MXhtVSks7o%3D 10.1016/j.stem.2008.10.015
    • Lamba DA, Gust J, Reh TA (2009a) Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice. Cell Stem Cell 4:73-79
    • (2009) Cell Stem Cell , vol.4 , pp. 73-79
    • Lamba, D.A.1    Gust, J.2    Reh, T.A.3
  • 66
    • 67849085412 scopus 로고    scopus 로고
    • Strategies for retinal repair: Cell replacement and regeneration
    • 19660646 1:CAS:528:DC%2BD1MXhsVeht7rI 10.1016/S0079-6123(09)17502-7
    • Lamba DA, Karl MO, Reh TA (2009b) Strategies for retinal repair: cell replacement and regeneration. Prog Brain Res 175:23-31
    • (2009) Prog Brain Res , vol.175 , pp. 23-31
    • Lamba, D.A.1    Karl, M.O.2    Reh, T.A.3
  • 67
    • 77649329847 scopus 로고    scopus 로고
    • Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells
    • 20098701 10.1371/journal.pone.0008763 1:CAS:528:DC%2BC3cXht1entLc%3D
    • Lamba DA, McUsic A, Hirata RK, Wang PR, Russell D, Reh TA (2010) Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells. PLoS One 5:e8763
    • (2010) PLoS One , vol.5 , pp. 8763
    • Lamba, D.A.1    McUsic, A.2    Hirata, R.K.3    Wang, P.R.4    Russell, D.5    Reh, T.A.6
  • 68
    • 48549084132 scopus 로고    scopus 로고
    • Molecular and cell-based approaches for neuroprotection in glaucoma
    • 18521011 10.1097/OPX.0b013e31817841f7
    • Lebrun-Julien F, Di Polo A (2008) Molecular and cell-based approaches for neuroprotection in glaucoma. Optom Vis Sci 85:417-424
    • (2008) Optom Vis Sci , vol.85 , pp. 417-424
    • Lebrun-Julien, F.1    Di Polo, A.2
  • 69
    • 0034757115 scopus 로고    scopus 로고
    • Animal and culture models of glaucoma for studying neuroprotection
    • 11592527
    • Levin LA (2001) Animal and culture models of glaucoma for studying neuroprotection. Eur J Ophthalmol 11 (Suppl 2):S23-S29
    • (2001) Eur J Ophthalmol , vol.11 , Issue.SUPPL. 2
    • Levin, L.A.1
  • 70
    • 0035222937 scopus 로고    scopus 로고
    • Retinal ganglion cells, glaucoma and neuroprotection
    • 11420983 1:STN:280:DC%2BD3MzmtVOqsw%3D%3D
    • Lipton SA (2001) Retinal ganglion cells, glaucoma and neuroprotection. Prog Brain Res 131:712-718
    • (2001) Prog Brain Res , vol.131 , pp. 712-718
    • Lipton, S.A.1
  • 71
    • 70349873363 scopus 로고    scopus 로고
    • Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration
    • 19521979 1:CAS:528:DC%2BD1MXhtlGnsbzE 10.1002/stem.149
    • Lu B, Malcuit C, Wang S, Girman S, Francis P, Lemieux L, Lanza R, Lund R (2009) Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration. Stem Cells 27:2126-2135
    • (2009) Stem Cells , vol.27 , pp. 2126-2135
    • Lu, B.1    Malcuit, C.2    Wang, S.3    Girman, S.4    Francis, P.5    Lemieux, L.6    Lanza, R.7    Lund, R.8
  • 72
    • 84857136772 scopus 로고    scopus 로고
    • Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
    • 22308465 1:CAS:528:DC%2BC38XivVKntb0%3D 10.1073/pnas.1121003109
    • Lujan E, Chanda S, Ahlenius H, Sudhof TC, Wernig M (2012) Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci USA 109:2527-2532
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 2527-2532
    • Lujan, E.1    Chanda, S.2    Ahlenius, H.3    Sudhof, T.C.4    Wernig, M.5
  • 74
    • 67649586414 scopus 로고    scopus 로고
    • Reprogramming retinal pigment epithelium to differentiate toward retinal neurons with Sox2
    • 19489100 1:CAS:528:DC%2BD1MXovFarur0%3D 10.1002/stem.48
    • Ma W, Yan RT, Li X, Wang SZ (2009) Reprogramming retinal pigment epithelium to differentiate toward retinal neurons with Sox2. Stem Cells 27:1376-1387
    • (2009) Stem Cells , vol.27 , pp. 1376-1387
    • Ma, W.1    Yan, R.T.2    Li, X.3    Wang, S.Z.4
  • 75
    • 84876720929 scopus 로고    scopus 로고
    • Translating induced pluripotent stem cells from bench to bedside: Application to retinal diseases
    • 23320477 10.2174/1566523211313020008
    • Maclaren R (2013) Translating induced pluripotent stem cells from bench to bedside: application to retinal diseases. Curr Gene Ther 13:139-151
    • (2013) Curr Gene Ther , vol.13 , pp. 139-151
    • Maclaren, R.1
  • 78
    • 84872127923 scopus 로고    scopus 로고
    • Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7
    • 23293286 1:CAS:528:DC%2BC3sXktF2ntL4%3D 10.1242/dev.085886
    • Mao CA, Cho JH, Wang J, Gao Z, Pan P, Tsai WW, Frishman LJ, Klein WH (2013) Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7. Development 140:541-551
    • (2013) Development , vol.140 , pp. 541-551
    • Mao, C.A.1    Cho, J.H.2    Wang, J.3    Gao, Z.4    Pan, P.5    Tsai, W.W.6    Frishman, L.J.7    Klein, W.H.8
  • 79
    • 80155144126 scopus 로고    scopus 로고
    • Induced pluripotent stem cells (iPSCs) and neurological disease modeling: Progress and promises
    • 21828073 1:CAS:528:DC%2BC3MXhtlyitLzK 10.1093/hmg/ddr336
    • Marchetto MC, Brennand KJ, Boyer LF, Gage FH (2011) Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises. Hum Mol Genet 20:R109-R115
    • (2011) Hum Mol Genet , vol.20
    • Marchetto, M.C.1    Brennand, K.J.2    Boyer, L.F.3    Gage, F.H.4
  • 80
    • 84859507797 scopus 로고    scopus 로고
    • Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells
    • 22267304 1:CAS:528:DC%2BC38XmsFOksL4%3D 10.1002/stem.1037
    • Mellough CB, Sernagor E, Moreno-Gimeno I, Steel DH, Lako M (2012) Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells. Stem Cells 30:673-686
    • (2012) Stem Cells , vol.30 , pp. 673-686
    • Mellough, C.B.1    Sernagor, E.2    Moreno-Gimeno, I.3    Steel, D.H.4    Lako, M.5
  • 86
    • 84859938636 scopus 로고    scopus 로고
    • Norrin: Molecular and functional properties of an angiogenic and neuroprotective growth factor
    • 22387751 1:CAS:528:DC%2BC38XlvFaktbg%3D 10.1016/j.preteyeres.2012.02.002
    • Ohlmann A, Tamm ER (2012) Norrin: molecular and functional properties of an angiogenic and neuroprotective growth factor. Prog Retin Eye Res 31:243-257
    • (2012) Prog Retin Eye Res , vol.31 , pp. 243-257
    • Ohlmann, A.1    Tamm, E.R.2
  • 87
    • 4544292252 scopus 로고    scopus 로고
    • Potential for neural regeneration after neurotoxic injury in the adult mammalian retina
    • 15353594 1:CAS:528:DC%2BD2cXnvFehs7Y%3D 10.1073/pnas.0402129101
    • Ooto S, Akagi T, Kageyama R, Akita J, Mandai M, Honda Y, Takahashi M (2004) Potential for neural regeneration after neurotoxic injury in the adult mammalian retina. Proc Natl Acad Sci USA 101:13654-13659
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13654-13659
    • Ooto, S.1    Akagi, T.2    Kageyama, R.3    Akita, J.4    Mandai, M.5    Honda, Y.6    Takahashi, M.7
  • 88
    • 34247140309 scopus 로고    scopus 로고
    • Wnt signaling promotes regeneration in the retina of adult mammals
    • 17428999 1:CAS:528:DC%2BD2sXks1OntLc%3D 10.1523/JNEUROSCI.4193-06.2007
    • Osakada F, Ooto S, Akagi T, Mandai M, Akaike A, Takahashi M (2007) Wnt signaling promotes regeneration in the retina of adult mammals. J Neurosci 27:4210-4219
    • (2007) J Neurosci , vol.27 , pp. 4210-4219
    • Osakada, F.1    Ooto, S.2    Akagi, T.3    Mandai, M.4    Akaike, A.5    Takahashi, M.6
  • 89
    • 66749139607 scopus 로고    scopus 로고
    • Stepwise differentiation of pluripotent stem cells into retinal cells
    • 19444239 1:CAS:528:DC%2BD1MXmsFWqtbs%3D 10.1038/nprot.2009.51
    • Osakada F, Ikeda H, Sasai Y, Takahashi M (2009a) Stepwise differentiation of pluripotent stem cells into retinal cells. Nat Protoc 4:811-824
    • (2009) Nat Protoc , vol.4 , pp. 811-824
    • Osakada, F.1    Ikeda, H.2    Sasai, Y.3    Takahashi, M.4
  • 90
    • 70349347145 scopus 로고    scopus 로고
    • In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction
    • 19671662 1:CAS:528:DC%2BD1MXht1WksbzK 10.1242/jcs.050393
    • Osakada F, Jin ZB, Hirami Y, Ikeda H, Danjyo T, Watanabe K, Sasai Y, Takahashi M (2009b) In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122:3169-3179
    • (2009) J Cell Sci , vol.122 , pp. 3169-3179
    • Osakada, F.1    Jin, Z.B.2    Hirami, Y.3    Ikeda, H.4    Danjyo, T.5    Watanabe, K.6    Sasai, Y.7    Takahashi, M.8
  • 91
    • 0032782221 scopus 로고    scopus 로고
    • The potential of neuroprotection in glaucoma treatment
    • 10537768 1:STN:280:DyaK1Mzgsl2htw%3D%3D 10.1097/00055735-199904000-00002
    • Osborne NN, Chidlow G, Nash MS, Wood JP (1999) The potential of neuroprotection in glaucoma treatment. Curr Opin Ophthalmol 10:82-92
    • (1999) Curr Opin Ophthalmol , vol.10 , pp. 82-92
    • Osborne, N.N.1    Chidlow, G.2    Nash, M.S.3    Wood, J.P.4
  • 94
    • 0032889607 scopus 로고    scopus 로고
    • Neuronal death in glaucoma
    • 9920498 1:STN:280:DyaK1M7hslahtA%3D%3D 10.1016/S1350-9462(98)00014-7
    • Quigley HA (1999) Neuronal death in glaucoma. Prog Retin Eye Res 18:39-57
    • (1999) Prog Retin Eye Res , vol.18 , pp. 39-57
    • Quigley, H.A.1
  • 95
    • 33644655886 scopus 로고    scopus 로고
    • The number of people with glaucoma worldwide in 2010 and 2020
    • 16488940 1:STN:280:DC%2BD28%2FpvFOjsA%3D%3D 10.1136/bjo.2005.081224
    • Quigley HA, Broman AT (2006) The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262-267
    • (2006) Br J Ophthalmol , vol.90 , pp. 262-267
    • Quigley, H.A.1    Broman, A.T.2
  • 96
    • 77953109819 scopus 로고    scopus 로고
    • Directing human embryonic stem cells to a retinal fate
    • 20336521 1:CAS:528:DC%2BC3cXovVKjt7Y%3D 10.1007/978-1-60761-691-7-9
    • Reh TA, Lamba D, Gust J (2010) Directing human embryonic stem cells to a retinal fate. Methods Mol Biol 636:139-153
    • (2010) Methods Mol Biol , vol.636 , pp. 139-153
    • Reh, T.A.1    Lamba, D.2    Gust, J.3
  • 97
    • 0034023609 scopus 로고    scopus 로고
    • Neuroprotection: Is it already applicable to glaucoma therapy?
    • 10848224 1:STN:280:DC%2BD3M%2FgtlymtQ%3D%3D 10.1097/00055735-200004000- 00002
    • Ritch R (2000) Neuroprotection: is it already applicable to glaucoma therapy? Curr Opin Ophthalmol 11:78-84
    • (2000) Curr Opin Ophthalmol , vol.11 , pp. 78-84
    • Ritch, R.1
  • 98
    • 78751677843 scopus 로고    scopus 로고
    • The stem cell potential of glia: Lessons from reactive gliosis
    • 21248788 1:CAS:528:DC%2BC3MXnvVKnsw%3D%3D 10.1038/nrn2978
    • Robel S, Berninger B, Gotz M (2011) The stem cell potential of glia: lessons from reactive gliosis. Nat Rev Neurosci 12:88-104
    • (2011) Nat Rev Neurosci , vol.12 , pp. 88-104
    • Robel, S.1    Berninger, B.2    Gotz, M.3
  • 100
    • 84873410997 scopus 로고    scopus 로고
    • Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo
    • 23334497 1:CAS:528:DC%2BC3sXhtFSnt7s%3D 10.1038/ncb2660
    • Rouaux C, Arlotta P (2013) Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nat Cell Biol 15:214-221
    • (2013) Nat Cell Biol , vol.15 , pp. 214-221
    • Rouaux, C.1    Arlotta, P.2
  • 101
    • 82155163896 scopus 로고    scopus 로고
    • Pluripotent human stem cells for the treatment of retinal disease
    • 21520078 1:CAS:528:DC%2BC3MXhsFartLvP 10.1002/jcp.22814
    • Rowland TJ, Buchholz DE, Clegg DO (2012) Pluripotent human stem cells for the treatment of retinal disease. J Cell Physiol 227:457-466
    • (2012) J Cell Physiol , vol.227 , pp. 457-466
    • Rowland, T.J.1    Buchholz, D.E.2    Clegg, D.O.3
  • 102
    • 70450285340 scopus 로고    scopus 로고
    • Technical challenges in using human induced pluripotent stem cells to model disease
    • 19951687 1:CAS:528:DC%2BC3cXht1eqtbs%3D 10.1016/j.stem.2009.11.009
    • Saha K, Jaenisch R (2009) Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell 5:584-595
    • (2009) Cell Stem Cell , vol.5 , pp. 584-595
    • Saha, K.1    Jaenisch, R.2
  • 103
    • 84867865709 scopus 로고    scopus 로고
    • In vitro organogenesis in three dimensions: Self-organising stem cells
    • 23093423 1:CAS:528:DC%2BC38XhvVKltrnI 10.1242/dev.079590
    • Sasai Y, Eiraku M, Suga H (2012) In vitro organogenesis in three dimensions: self-organising stem cells. Development 139:4111-4121
    • (2012) Development , vol.139 , pp. 4111-4121
    • Sasai, Y.1    Eiraku, M.2    Suga, H.3
  • 104
    • 84862766344 scopus 로고    scopus 로고
    • Cell-replacement therapy and neural repair in the retina
    • 22354517 1:CAS:528:DC%2BC38XovVWls7c%3D 10.1007/s00441-012-1335-6
    • Schmeer CW, Wohl SG, Isenmann S (2012) Cell-replacement therapy and neural repair in the retina. Cell Tissue Res 349:363-374
    • (2012) Cell Tissue Res , vol.349 , pp. 363-374
    • Schmeer, C.W.1    Wohl, S.G.2    Isenmann, S.3
  • 106
    • 84866171956 scopus 로고    scopus 로고
    • Derivation of human differential photoreceptor-like cells from the iris by defined combinations of CRX, RX and NEUROD
    • 22558175 1:CAS:528:DC%2BC38Xnt1Ohs78%3D 10.1371/journal.pone.0035611
    • Seko Y, Azuma N, Kaneda M, Nakatani K, Miyagawa Y, Noshiro Y, Kurokawa R, Okano H, Umezawa A (2012) Derivation of human differential photoreceptor-like cells from the iris by defined combinations of CRX, RX and NEUROD. PLoS One 7:e35611
    • (2012) PLoS One , vol.7 , pp. 35611
    • Seko, Y.1    Azuma, N.2    Kaneda, M.3    Nakatani, K.4    Miyagawa, Y.5    Noshiro, Y.6    Kurokawa, R.7    Okano, H.8    Umezawa, A.9
  • 110
    • 84866088266 scopus 로고    scopus 로고
    • Human Muller glia with stem cell characteristics differentiate into retinal ganglion cell (RGC) precursors in vitro and partially restore RGC function in vivo following transplantation
    • 23197778 1:CAS:528:DC%2BC38Xns12lt70%3D 10.5966/sctm.2011-0005
    • Singhal S, Bhatia B, Jayaram H, Becker S, Jones MF, Cottrill PB, Khaw PT, Salt TE, Limb GA (2012) Human Muller glia with stem cell characteristics differentiate into retinal ganglion cell (RGC) precursors in vitro and partially restore RGC function in vivo following transplantation. Stem Cells Transl Med 1:188-199
    • (2012) Stem Cells Transl Med , vol.1 , pp. 188-199
    • Singhal, S.1    Bhatia, B.2    Jayaram, H.3    Becker, S.4    Jones, M.F.5    Cottrill, P.B.6    Khaw, P.T.7    Salt, T.E.8    Limb, G.A.9
  • 111
    • 84870156157 scopus 로고    scopus 로고
    • Medicine. iPSC disease modeling
    • 23197518 10.1126/science.1227682
    • Soldner F, Jaenisch R (2012) Medicine. iPSC disease modeling. Science 338:1155-1156
    • (2012) Science , vol.338 , pp. 1155-1156
    • Soldner, F.1    Jaenisch, R.2
  • 112
    • 73049105546 scopus 로고    scopus 로고
    • Modeling disease in human ESCs using an efficient BAC-based homologous recombination system
    • 20074536 1:CAS:528:DC%2BC3cXkvVWhsrg%3D 10.1016/j.stem.2009.11.016
    • Song H, Chung SK, Xu Y (2010) Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. Cell Stem Cell 6:80-89
    • (2010) Cell Stem Cell , vol.6 , pp. 80-89
    • Song, H.1    Chung, S.K.2    Xu, Y.3
  • 113
    • 84862826853 scopus 로고    scopus 로고
    • Establishment of retinal progenitor cell clones by transfection with Pax6 gene of mouse induced pluripotent stem (iPS) cells
    • 22230895 1:CAS:528:DC%2BC38XhvVGgtrg%3D 10.1016/j.neulet.2011.12.055
    • Suzuki N, Shimizu J, Takai K, Arimitsu N, Ueda Y, Takada E, Hirotsu C, Suzuki T, Fujiwara N, Tadokoro M (2012) Establishment of retinal progenitor cell clones by transfection with Pax6 gene of mouse induced pluripotent stem (iPS) cells. Neurosci Lett 509:116-120
    • (2012) Neurosci Lett , vol.509 , pp. 116-120
    • Suzuki, N.1    Shimizu, J.2    Takai, K.3    Arimitsu, N.4    Ueda, Y.5    Takada, E.6    Hirotsu, C.7    Suzuki, T.8    Fujiwara, N.9    Tadokoro, M.10
  • 115
    • 70349269509 scopus 로고    scopus 로고
    • Considering the evolution of regeneration in the central nervous system
    • 19763104 1:CAS:528:DC%2BD1MXhtFCns77M 10.1038/nrn2707
    • Tanaka EM, Ferretti P (2009) Considering the evolution of regeneration in the central nervous system. Nat Rev Neurosci 10:713-723
    • (2009) Nat Rev Neurosci , vol.10 , pp. 713-723
    • Tanaka, E.M.1    Ferretti, P.2
  • 117
    • 84856112882 scopus 로고    scopus 로고
    • Diseases in a dish: Modeling human genetic disorders using induced pluripotent cells
    • 22146428 1:CAS:528:DC%2BC3MXhsFOitLvM 10.1038/nm.2504
    • Tiscornia G, Vivas EL, Izpisua Belmonte JC (2011) Diseases in a dish: modeling human genetic disorders using induced pluripotent cells. Nat Med 17:1570-1576
    • (2011) Nat Med , vol.17 , pp. 1570-1576
    • Tiscornia, G.1    Vivas, E.L.2    Izpisua Belmonte, J.C.3
  • 118
    • 79955711373 scopus 로고    scopus 로고
    • Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice
    • 21559507 1:CAS:528:DC%2BC3MXls1Kktrw%3D 10.1371/journal.pone.0018992
    • Tucker BA, Park IH, Qi SD, Klassen HJ, Jiang C, Yao J, Redenti S, Daley GQ, Young MJ (2011) Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. PLoS One 6:e18992
    • (2011) PLoS One , vol.6 , pp. 18992
    • Tucker, B.A.1    Park, I.H.2    Qi, S.D.3    Klassen, H.J.4    Jiang, C.5    Yao, J.6    Redenti, S.7    Daley, G.Q.8    Young, M.J.9
  • 119
    • 84865326893 scopus 로고    scopus 로고
    • P53 is required for the developmental restriction in Muller glial proliferation in mouse retina
    • 22777914 10.1002/glia.22377
    • Ueki Y, Karl MO, Sudar S, Pollak J, Taylor RJ, Loeffler K, Wilken MS, Reardon S, Reh TA (2012) P53 is required for the developmental restriction in Muller glial proliferation in mouse retina. Glia 60:1579-1589
    • (2012) Glia , vol.60 , pp. 1579-1589
    • Ueki, Y.1    Karl, M.O.2    Sudar, S.3    Pollak, J.4    Taylor, R.J.5    Loeffler, K.6    Wilken, M.S.7    Reardon, S.8    Reh, T.A.9
  • 120
    • 80054726357 scopus 로고    scopus 로고
    • Direct lineage conversions: Unnatural but useful?
    • 21997635 1:CAS:528:DC%2BC3MXhtlWltb%2FF 10.1038/nbt.1946
    • Vierbuchen T, Wernig M (2011) Direct lineage conversions: unnatural but useful? Nat Biotechnol 29:892-907
    • (2011) Nat Biotechnol , vol.29 , pp. 892-907
    • Vierbuchen, T.1    Wernig, M.2
  • 121
    • 84866780162 scopus 로고    scopus 로고
    • Molecular roadblocks for cellular reprogramming
    • 23020854 1:CAS:528:DC%2BC38XhsVaqt7vF 10.1016/j.molcel.2012.09.008
    • Vierbuchen T, Wernig M (2012) Molecular roadblocks for cellular reprogramming. Mol Cell 47:827-838
    • (2012) Mol Cell , vol.47 , pp. 827-838
    • Vierbuchen, T.1    Wernig, M.2
  • 123
    • 84872106229 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis model derived from human embryonic stem cells overexpressing mutant superoxide dismutase 1
    • 23197818 1:CAS:528:DC%2BC38XhtVOmtrvP 10.5966/sctm.2011-0061
    • Wada T, Goparaju SK, Tooi N, Inoue H, Takahashi R, Nakatsuji N, Aiba K (2012) Amyotrophic lateral sclerosis model derived from human embryonic stem cells overexpressing mutant superoxide dismutase 1. Stem Cells Transl Med 1:396-402
    • (2012) Stem Cells Transl Med , vol.1 , pp. 396-402
    • Wada, T.1    Goparaju, S.K.2    Tooi, N.3    Inoue, H.4    Takahashi, R.5    Nakatsuji, N.6    Aiba, K.7
  • 124
    • 34748822325 scopus 로고    scopus 로고
    • Sonic hedgehog promotes stem-cell potential of Muller glia in the mammalian retina
    • 17880919 1:CAS:528:DC%2BD2sXhtFWgs77P 10.1016/j.bbrc.2007.08.178
    • Wan J, Zheng H, Xiao HL, She ZJ, Zhou GM (2007) Sonic hedgehog promotes stem-cell potential of Muller glia in the mammalian retina. Biochem Biophys Res Commun 363:347-354
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 347-354
    • Wan, J.1    Zheng, H.2    Xiao, H.L.3    She, Z.J.4    Zhou, G.M.5
  • 125
    • 38549117781 scopus 로고    scopus 로고
    • Preferential regeneration of photoreceptor from Muller glia after retinal degeneration in adult rat
    • 18155124 1:CAS:528:DC%2BD1cXhtlOmtLY%3D 10.1016/j.visres.2007.11.002
    • Wan J, Zheng H, Chen ZL, Xiao HL, Shen ZJ, Zhou GM (2008) Preferential regeneration of photoreceptor from Muller glia after retinal degeneration in adult rat. Vision Res 48:223-234
    • (2008) Vision Res , vol.48 , pp. 223-234
    • Wan, J.1    Zheng, H.2    Chen, Z.L.3    Xiao, H.L.4    Shen, Z.J.5    Zhou, G.M.6
  • 126
    • 84857004538 scopus 로고    scopus 로고
    • HB-EGF is necessary and sufficient for Muller glia dedifferentiation and retina regeneration
    • 22340497 1:CAS:528:DC%2BC38Xit12gtLc%3D 10.1016/j.devcel.2011.11.020
    • Wan J, Ramachandran R, Goldman D (2012) HB-EGF is necessary and sufficient for Muller glia dedifferentiation and retina regeneration. Dev Cell 22:334-347
    • (2012) Dev Cell , vol.22 , pp. 334-347
    • Wan, J.1    Ramachandran, R.2    Goldman, D.3
  • 128
    • 77954682596 scopus 로고    scopus 로고
    • Generating retinal neurons by reprogramming retinal pigment epithelial cells
    • 20528097 1:CAS:528:DC%2BC3cXoslaisLk%3D 10.1517/14712598.2010.495218
    • Wang SZ, Ma W, Yan RT, Mao W (2010b) Generating retinal neurons by reprogramming retinal pigment epithelial cells. Expert Opin Biol Ther 10:1227-1239
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 1227-1239
    • Wang, S.Z.1    Ma, W.2    Yan, R.T.3    Mao, W.4
  • 129
    • 84555189036 scopus 로고    scopus 로고
    • Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration
    • 21896868 1:CAS:528:DC%2BC38XmsVOl 10.1167/iovs.11-7849
    • Wang W, Fernandez de Castro J, Vukmanic E, Zhou L, Emery D, Demarco PJ, Kaplan HJ, Dean DC (2011) Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration. Invest Ophthalmol Vis Sci 52:7917-7923
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 7917-7923
    • Wang, W.1    Fernandez De Castro, J.2    Vukmanic, E.3    Zhou, L.4    Emery, D.5    Demarco, P.J.6    Kaplan, H.J.7    Dean, D.C.8
  • 130
    • 0036700129 scopus 로고    scopus 로고
    • Neurobiology of glaucomatous optic neuropathy: Diverse cellular events in neurodegeneration and neuroprotection
    • 12392055 1:CAS:528:DC%2BD38XnvFKitr0%3D 10.1385/MN:26:1:045
    • Wax MB, Tezel G (2002) Neurobiology of glaucomatous optic neuropathy: diverse cellular events in neurodegeneration and neuroprotection. Mol Neurobiol 26:45-55
    • (2002) Mol Neurobiol , vol.26 , pp. 45-55
    • Wax, M.B.1    Tezel, G.2
  • 131
    • 0036201295 scopus 로고    scopus 로고
    • Current understanding of neuroprotection in glaucoma
    • 11880717 10.1097/00055735-200204000-00002
    • Wein FB, Levin LA (2002) Current understanding of neuroprotection in glaucoma. Curr Opin Ophthalmol 13:61-67
    • (2002) Curr Opin Ophthalmol , vol.13 , pp. 61-67
    • Wein, F.B.1    Levin, L.A.2
  • 132
    • 84862534518 scopus 로고    scopus 로고
    • Stem cell therapies could change medicine. if they get the chance
    • 22704505 1:CAS:528:DC%2BC38XosFCiuro%3D 10.1016/j.stem.2012.05.014
    • Weissman I (2012) Stem cell therapies could change medicine. if they get the chance. Cell Stem Cell 10:663-665
    • (2012) Cell Stem Cell , vol.10 , pp. 663-665
    • Weissman, I.1
  • 133
    • 84863115284 scopus 로고    scopus 로고
    • CNTF and retina
    • 22182585 1:CAS:528:DC%2BC38Xis1emu74%3D 10.1016/j.preteyeres.2011.11.005
    • Wen R, Tao W, Li Y, Sieving PA (2012) CNTF and retina. Prog Retin Eye Res 31:136-151
    • (2012) Prog Retin Eye Res , vol.31 , pp. 136-151
    • Wen, R.1    Tao, W.2    Li, Y.3    Sieving, P.A.4
  • 134
    • 67849106910 scopus 로고    scopus 로고
    • Cell transplantation strategies for retinal repair
    • 19660645 1:CAS:528:DC%2BD1MXhsVeht7rP 10.1016/S0079-6123(09)17501-5
    • West EL, Pearson RA, MacLaren RE, Sowden JC, Ali RR (2009) Cell transplantation strategies for retinal repair. Prog Brain Res 175:3-21
    • (2009) Prog Brain Res , vol.175 , pp. 3-21
    • West, E.L.1    Pearson, R.A.2    Maclaren, R.E.3    Sowden, J.C.4    Ali, R.R.5
  • 138
    • 84856963831 scopus 로고    scopus 로고
    • Gene therapy for retinal ganglion cell neuroprotection in glaucoma
    • 21975466 1:CAS:528:DC%2BC3MXht1yjsr3M 10.1038/gt.2011.142
    • Wilson AM, Di Polo A (2012) Gene therapy for retinal ganglion cell neuroprotection in glaucoma. Gene Ther 19:127-136
    • (2012) Gene Ther , vol.19 , pp. 127-136
    • Wilson, A.M.1    Di Polo, A.2
  • 139
    • 80052785190 scopus 로고    scopus 로고
    • What has gene expression profiling taught us about glaucoma?
    • 20946895 1:CAS:528:DC%2BC3MXhtF2rtL7E 10.1016/j.exer.2010.10.001
    • Yang Z, Zack DJ (2011) What has gene expression profiling taught us about glaucoma? Exp Eye Res 93:191-195
    • (2011) Exp Eye Res , vol.93 , pp. 191-195
    • Yang, Z.1    Zack, D.J.2
  • 140
    • 84863225073 scopus 로고    scopus 로고
    • Ophthalmic drug discovery: Novel targets and mechanisms for retinal diseases and glaucoma
    • 22699774 1:CAS:528:DC%2BC38Xos1egtbw%3D 10.1038/nrd3745
    • Zhang K, Zhang L, Weinreb RN (2012) Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma. Nat Rev Drug Discov 11:541-559
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 541-559
    • Zhang, K.1    Zhang, L.2    Weinreb, R.N.3
  • 141
    • 84872869816 scopus 로고    scopus 로고
    • Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium
    • 23358448 1:CAS:528:DC%2BC3sXit1Chsb0%3D 10.1371/journal.pone.0054552
    • Zhu Y, Carido M, Meinhardt A, Kurth T, Karl MO, Ader M, Tanaka EM (2013) Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium. PLoS One 8:e54552
    • (2013) PLoS One , vol.8 , pp. 54552
    • Zhu, Y.1    Carido, M.2    Meinhardt, A.3    Kurth, T.4    Karl, M.O.5    Ader, M.6    Tanaka, E.M.7
  • 143
    • 77957906144 scopus 로고    scopus 로고
    • Eye field specification in Xenopus laevis
    • 20959162 10.1016/B978-0-12-385044-7.00002-3
    • Zuber ME (2010) Eye field specification in Xenopus laevis. Curr Top Dev Biol 93:29-60
    • (2010) Curr Top Dev Biol , vol.93 , pp. 29-60
    • Zuber, M.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.