메뉴 건너뛰기




Volumn 15, Issue 4, 2013, Pages 291-302

Newer treatments in the management of pediatric asthma

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BENRALIZUMAB; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CICLESONIDE; CLARITHROMYCIN; CORTICOSTEROID; DEXAMETHASONE; ETANERCEPT; FORMOTEROL; GOLIMUMAB; IMATINIB; IMMUNOGLOBULIN E; INFLIXIMAB; ITRACONAZOLE; MACROLIDE; MASITINIB; MEPOLIZUMAB; METHYLPREDNISOLONE; MOMETASONE FUROATE; MONTELUKAST; OMALIZUMAB; PITRAKINRA; PLACEBO; PREDNISOLONE; RESLIZUMAB; THEOPHYLLINE; TRALOKINUMAB; TROLEANDOMYCIN; UNINDEXED DRUG; VITAMIN D;

EID: 84880766820     PISSN: 11745878     EISSN: 11792019     Source Type: Journal    
DOI: 10.1007/s40272-013-0020-x     Document Type: Review
Times cited : (9)

References (136)
  • 1
    • 71749107897 scopus 로고    scopus 로고
    • Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in the Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
    • 895-902.e1-4
    • Haselkorn T, Fish JE, Zeiger RS, Szefler SJ, Miller DP, Chipps BE, et al. Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2009;124(5):895-902.e1-4.
    • (2009) J Allergy Clin Immunol. , vol.124 , Issue.5
    • Haselkorn, T.1    Fish, J.E.2    Zeiger, R.S.3    Szefler, S.J.4    Miller, D.P.5    Chipps, B.E.6
  • 2
    • 78650921930 scopus 로고    scopus 로고
    • Progressive airflow limitation is a feature of children with severe asthma
    • 21211661 10.1016/j.jaci.2010.10.036
    • Fitzpatrick AM, Teague WG. Progressive airflow limitation is a feature of children with severe asthma. J Allergy Clin Immunol. 2011;127(1):282-4.
    • (2011) J Allergy Clin Immunol , vol.127 , Issue.1 , pp. 282-284
    • Fitzpatrick, A.M.1    Teague, W.G.2
  • 5
    • 84863393694 scopus 로고    scopus 로고
    • Alveolarization continues during childhood and adolescence: New evidence from helium-3 magnetic resonance
    • 22071328 1:CAS:528:DC%2BC38XislWgtr4%3D 10.1164/rccm.201107-1348OC
    • Narayanan M, Owers-Bradley J, Beardsmore CS, Mada M, Ball I, Garipov R, et al. Alveolarization continues during childhood and adolescence: new evidence from helium-3 magnetic resonance. Am J Respir Crit Care Med. 2012;185(2):186-91.
    • (2012) Am J Respir Crit Care Med , vol.185 , Issue.2 , pp. 186-191
    • Narayanan, M.1    Owers-Bradley, J.2    Beardsmore, C.S.3    Mada, M.4    Ball, I.5    Garipov, R.6
  • 7
    • 77954033984 scopus 로고    scopus 로고
    • New therapies for asthma: Is there any progress?
    • 20554041 1:CAS:528:DC%2BC3cXotVChtbs%3D 10.1016/j.tips.2010.04.009
    • Barnes PJ. New therapies for asthma: is there any progress? Trends Pharmacol Sci. 2010;31(7):335-43.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.7 , pp. 335-343
    • Barnes, P.J.1
  • 8
    • 84455179025 scopus 로고    scopus 로고
    • Severe asthma: Advances in current management and future therapy
    • 22196524 1:CAS:528:DC%2BC3MXhs1yrsb7I 10.1016/j.jaci.2011.11.006
    • Barnes PJ. Severe asthma: advances in current management and future therapy. J Allergy Clin Immunol. 2012;129(1):48-59.
    • (2012) J Allergy Clin Immunol , vol.129 , Issue.1 , pp. 48-59
    • Barnes, P.J.1
  • 10
    • 84864582201 scopus 로고    scopus 로고
    • New and future developments of therapy for asthma in children
    • 10.1183/1025448x.10018310 1:CAS:528:DC%2BC38XhtVOmsLnI
    • Sly PD, Jones CM. New and future developments of therapy for asthma in children. Eur Respir Monogr. 2012;56:224-34.
    • (2012) Eur Respir Monogr , vol.56 , pp. 224-234
    • Sly, P.D.1    Jones, C.M.2
  • 11
    • 78650899318 scopus 로고    scopus 로고
    • Advances in pediatric asthma in 2010: Addressing the major issues
    • 21211645 10.1016/j.jaci.2010.11.018
    • Szefler SJ. Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 2011;127(1):102-15.
    • (2011) J Allergy Clin Immunol , vol.127 , Issue.1 , pp. 102-115
    • Szefler, S.J.1
  • 12
    • 84863836184 scopus 로고    scopus 로고
    • International consensus on (ICON) pediatric asthma
    • 22702533 1:CAS:528:DC%2BC38XhsVartb%2FO 10.1111/j.1398-9995.2012.02865.x
    • Papadopoulos NG, Arakawa H, Carlsen KH, Custovic A, Gern J, Lemanske R, et al. International consensus on (ICON) pediatric asthma. Allergy. 2012;67(8):976-97.
    • (2012) Allergy , vol.67 , Issue.8 , pp. 976-997
    • Papadopoulos, N.G.1    Arakawa, H.2    Carlsen, K.H.3    Custovic, A.4    Gern, J.5    Lemanske, R.6
  • 13
    • 0028870592 scopus 로고
    • Asthma and wheezing in the first six years of life. The Group Health Medical Associates
    • 7800004 1:STN:280:DyaK2M%2FpvVSrtQ%3D%3D 10.1056/NEJM199501193320301
    • Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med. 1995;332(3):133-8.
    • (1995) N Engl J Med , vol.332 , Issue.3 , pp. 133-138
    • Martinez, F.D.1    Wright, A.L.2    Taussig, L.M.3    Holberg, C.J.4    Halonen, M.5    Morgan, W.J.6
  • 16
    • 33646488054 scopus 로고    scopus 로고
    • Long-term inhaled corticosteroids in preschool children at high risk for asthma
    • 16687711 1:CAS:528:DC%2BD28XksFGhs70%3D 10.1056/NEJMoa051378
    • Guilbert TW, Morgan WJ, Zeiger RS, Mauger DT, Boehmer SJ, Szefler SJ, et al. Long-term inhaled corticosteroids in preschool children at high risk for asthma. N Engl J Med. 2006;354(19):1985-97.
    • (2006) N Engl J Med , vol.354 , Issue.19 , pp. 1985-1997
    • Guilbert, T.W.1    Morgan, W.J.2    Zeiger, R.S.3    Mauger, D.T.4    Boehmer, S.J.5    Szefler, S.J.6
  • 21
    • 33746563608 scopus 로고    scopus 로고
    • The functional benefit of anti-inflammatory aerosols in the lung periphery
    • DOI 10.1016/j.jaci.2006.04.056, PII S0091674906010578
    • Verbanck S, Schuermans D, Paiva M, Vincken W. The functional benefit of anti-inflammatory aerosols in the lung periphery. J Allergy Clin Immunol. 2006;118(2):340-6. (Pubitemid 44142721)
    • (2006) Journal of Allergy and Clinical Immunology , vol.118 , Issue.2 , pp. 340-346
    • Verbanck, S.1    Schuermans, D.2    Paiva, M.3    Vincken, W.4
  • 22
    • 58349084874 scopus 로고    scopus 로고
    • Ventilation heterogeneity in children with well controlled asthma with normal spirometry indicates residual airways disease
    • 18678703 1:STN:280:DC%2BD1M%2FgtV2nug%3D%3D 10.1136/thx.2007.095018
    • Macleod KA, Horsley AR, Bell NJ, Greening AP, Innes JA, Cunningham S. Ventilation heterogeneity in children with well controlled asthma with normal spirometry indicates residual airways disease. Thorax. 2009;64(1):33-7.
    • (2009) Thorax , vol.64 , Issue.1 , pp. 33-37
    • Macleod, K.A.1    Horsley, A.R.2    Bell, N.J.3    Greening, A.P.4    Innes, J.A.5    Cunningham, S.6
  • 23
  • 27
    • 79955751312 scopus 로고    scopus 로고
    • Omalizumab in severe allergic asthma inadequately controlled with standard therapy: A randomized trial
    • 10.7326/0003-4819-154-9-201105030-00002
    • Hanania NA, Alpan O, Hamilos DL, Condemi JJ, Reyes-Rivera I, Zhu J, et al. Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial. Annals Intern Med. 2011;154(9):573-82.
    • (2011) Annals Intern Med , vol.154 , Issue.9 , pp. 573-582
    • Hanania, N.A.1    Alpan, O.2    Hamilos, D.L.3    Condemi, J.J.4    Reyes-Rivera, I.5    Zhu, J.6
  • 28
    • 78649673636 scopus 로고    scopus 로고
    • Efficacy and safety of subcutaneous omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: A systematic review
    • 20688929 1:CAS:528:DC%2BC3MXhvVGisbc%3D 10.1378/chest.10-1194
    • Rodrigo GJ, Neffen H, Castro-Rodriguez JA. Efficacy and safety of subcutaneous omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: a systematic review. Chest. 2011;139(1):28-35.
    • (2011) Chest , vol.139 , Issue.1 , pp. 28-35
    • Rodrigo, G.J.1    Neffen, H.2    Castro-Rodriguez, J.A.3
  • 29
    • 0035434688 scopus 로고    scopus 로고
    • Treatment of childhood asthma with anti-immunoglobulin e antibody (omalizumab)
    • 11483846 1:STN:280:DC%2BD3MvjvVWqsw%3D%3D 10.1542/peds.108.2.e36
    • Milgrom H, Berger W, Nayak A, Gupta N, Pollard S, McAlary M, et al. Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab). Pediatrics. 2001;108(2):E36.
    • (2001) Pediatrics , vol.108 , Issue.2 , pp. 36
    • Milgrom, H.1    Berger, W.2    Nayak, A.3    Gupta, N.4    Pollard, S.5    McAlary, M.6
  • 30
    • 79952795093 scopus 로고    scopus 로고
    • Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children
    • 21410369 1:CAS:528:DC%2BC3MXjtlSlsbs%3D 10.1056/NEJMoa1009705
    • Busse WW, Morgan WJ, Gergen PJ, Mitchell HE, Gern JE, Liu AH, et al. Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. New Engl J Med. 2011;364(11):1005-15.
    • (2011) New Engl J Med , vol.364 , Issue.11 , pp. 1005-1015
    • Busse, W.W.1    Morgan, W.J.2    Gergen, P.J.3    Mitchell, H.E.4    Gern, J.E.5    Liu, A.H.6
  • 32
    • 0036832242 scopus 로고    scopus 로고
    • Omalizumab improves asthma-related quality of life in children with allergic asthma
    • 12415061 10.1542/peds.110.5.e55
    • Lemanske RF Jr, Nayak A, McAlary M, Everhard F, Fowler-Taylor A, Gupta N. Omalizumab improves asthma-related quality of life in children with allergic asthma. Pediatrics. 2002;110(5):e55.
    • (2002) Pediatrics , vol.110 , Issue.5 , pp. 55
    • Lemanske, Jr.R.F.1    Nayak, A.2    McAlary, M.3    Everhard, F.4    Fowler-Taylor, A.5    Gupta, N.6
  • 33
    • 84863307371 scopus 로고    scopus 로고
    • The oral corticosteroid-sparing effect of omalizumab in children with severe asthma
    • 22685051 10.1136/archdischild-2011-301570
    • Brodlie M, McKean MC, Moss S, Spencer DA. The oral corticosteroid-sparing effect of omalizumab in children with severe asthma. Arch Dis Child. 2012;97(7):604-9.
    • (2012) Arch Dis Child , vol.97 , Issue.7 , pp. 604-609
    • Brodlie, M.1    McKean, M.C.2    Moss, S.3    Spencer, D.A.4
  • 34
    • 79959776423 scopus 로고    scopus 로고
    • Anti-IgE for asthma in inner-city children
    • (author reply 7-8)
    • Pavord ID, Bush A. Anti-IgE for asthma in inner-city children. New Engl J Med. 2011;364(26):2556-7 (author reply 7-8).
    • (2011) New Engl J Med. , vol.364 , Issue.26 , pp. 2556-2557
    • Pavord, I.D.1    Bush, A.2
  • 35
    • 0043240429 scopus 로고    scopus 로고
    • Evaluation of long-term safety of the anti-IgE antibody, omalizumab, in children with allergic asthma
    • Berger W, Gupta N, McAlary M, Fowler-Taylor A. Evaluation of long-term safety of the anti-IgE antibody, omalizumab, in children with allergic asthma. Ann Allergy Asthma Immunol. 2003;91(2):182-8. (Pubitemid 36999479)
    • (2003) Annals of Allergy, Asthma and Immunology , vol.91 , Issue.2 , pp. 182-188
    • Berger, W.E.1    Gupta, N.2    McAlary, M.3    Fowler-Taylor, A.4
  • 36
    • 36749043895 scopus 로고    scopus 로고
    • Delayed onset and protracted progression of anaphylaxis after omalizumab administration in patients with asthma
    • DOI 10.1016/j.jaci.2007.09.022, PII S0091674907017812
    • Limb SL, Starke PR, Lee CE, Chowdhury BA. Delayed onset and protracted progression of anaphylaxis after omalizumab administration in patients with asthma. J Allergy Clin Immunol. 2007;120(6):1378-81. (Pubitemid 350216608)
    • (2007) Journal of Allergy and Clinical Immunology , vol.120 , Issue.6 , pp. 1378-1381
    • Limb, S.L.1    Starke, P.R.2    Lee, C.E.3    Chowdhury, B.A.4
  • 38
    • 84867292926 scopus 로고    scopus 로고
    • Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years: A NICE single technology appraisal
    • Burch J, Griffin S, McKenna C, Walker S, Paton J, Wright K, et al. Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years: a NICE single technology appraisal. Pharmacoeconomics. 2012;30(11):991-1104.
    • (2012) Pharmacoeconomics , vol.30 , Issue.11 , pp. 991-1104
    • Burch, J.1    Griffin, S.2    McKenna, C.3    Walker, S.4    Paton, J.5    Wright, K.6
  • 39
    • 4344622274 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of omalizumab in adults and adolescents with moderate-to-severe allergic asthma
    • DOI 10.1016/j.jaci.2004.05.049, PII S0091674904015635
    • Oba Y, Salzman GA. Cost-effectiveness analysis of omalizumab in adults and adolescents with moderate-to-severe allergic asthma. J Allergy Clin Immunol. 2004;114(2):265-9. (Pubitemid 39119022)
    • (2004) Journal of Allergy and Clinical Immunology , vol.114 , Issue.2 , pp. 265-269
    • Oba, Y.1    Salzman, G.A.2
  • 40
    • 84871370456 scopus 로고    scopus 로고
    • Omalizumab: NICE to USE you, to LOSE you NICE
    • 10.1136/thoraxjnl-2012-202482
    • Bush A, Pavord I. Omalizumab: NICE to USE you, to LOSE you NICE. Thorax. 2013;68:5-6.
    • (2013) Thorax , vol.68 , pp. 5-6
    • Bush, A.1    Pavord, I.2
  • 42
    • 78149450572 scopus 로고    scopus 로고
    • Adherence and asthma control with mometasone furoate versus fluticasone propionate in adolescents and young adults with mild asthma
    • 20831468 1:CAS:528:DC%2BC3cXhtl2rsLzK
    • Friedman HS, Navaratnam P, McLaughlin J. Adherence and asthma control with mometasone furoate versus fluticasone propionate in adolescents and young adults with mild asthma. J Asthma. 2010;47(9):994-1000.
    • (2010) J Asthma , vol.47 , Issue.9 , pp. 994-1000
    • Friedman, H.S.1    Navaratnam, P.2    McLaughlin, J.3
  • 43
    • 77954488656 scopus 로고    scopus 로고
    • Mometasone furoate in children with mild to moderate persistent asthma: A review of the evidence
    • 20593906 10.2165/11316220-000000000-00000
    • Milgrom H. Mometasone furoate in children with mild to moderate persistent asthma: a review of the evidence. Paediatr Drugs. 2010;12(4):213-21.
    • (2010) Paediatr Drugs , vol.12 , Issue.4 , pp. 213-221
    • Milgrom, H.1
  • 44
    • 80053220399 scopus 로고    scopus 로고
    • Effects of inhaled mometasone furoate on growth velocity and adrenal function: A placebo-controlled trial in children 4-9 years old with mild persistent asthma
    • 21854342 1:CAS:528:DC%2BC3MXht1ClurzF 10.3109/02770903.2011.604883
    • Skoner DP, Meltzer EO, Milgrom H, Stryszak P, Teper A, Staudinger H. Effects of inhaled mometasone furoate on growth velocity and adrenal function: a placebo-controlled trial in children 4-9 years old with mild persistent asthma. J Asthma. 2011;48(8):848-59.
    • (2011) J Asthma , vol.48 , Issue.8 , pp. 848-859
    • Skoner, D.P.1    Meltzer, E.O.2    Milgrom, H.3    Stryszak, P.4    Teper, A.5    Staudinger, H.6
  • 45
    • 33646176778 scopus 로고    scopus 로고
    • Once-daily ciclesonide in children: Efficacy and safety in asthma
    • 16615971 1:CAS:528:DC%2BD28Xjs1Kgurs%3D 10.1016/j.jpeds.2005.10.028
    • Gelfand EW, Georgitis JW, Noonan M, Ruff ME. Once-daily ciclesonide in children: efficacy and safety in asthma. J Pediatr. 2006;148(3):377-83.
    • (2006) J Pediatr , vol.148 , Issue.3 , pp. 377-383
    • Gelfand, E.W.1    Georgitis, J.W.2    Noonan, M.3    Ruff, M.E.4
  • 46
    • 33749565533 scopus 로고    scopus 로고
    • A comparative study of inhaled ciclesonide 160 μg/day and fluticasone propionate 176 μg/day in children with asthma
    • DOI 10.1002/ppul.20474
    • Pedersen S, Garcia Garcia ML, Manjra A, Theron I, Engelstatter R. A comparative study of inhaled ciclesonide 160 microg/day and fluticasone propionate 176 microg/day in children with asthma. Pediatr Pulmonol. 2006;41(10):954-61. (Pubitemid 44534813)
    • (2006) Pediatric Pulmonology , vol.41 , Issue.10 , pp. 954-961
    • Pedersen, S.1    Garcia, M.L.G.2    Manjra, A.3    Theron, I.4    Engelstatter, R.5
  • 47
    • 38049050194 scopus 로고    scopus 로고
    • Assessment of the long-term safety of inhaled ciclesonide on growth in children with asthma
    • 18070931 10.1542/peds.2006-2206
    • Skoner DP, Maspero J, Banerji D. Assessment of the long-term safety of inhaled ciclesonide on growth in children with asthma. Pediatrics. 2008;121(1):e1-14.
    • (2008) Pediatrics , vol.121 , Issue.1
    • Skoner, D.P.1    Maspero, J.2    Banerji, D.3
  • 48
    • 82955195398 scopus 로고    scopus 로고
    • Efficacy of a fixed combination of ciclesonide and formoterol: The EXCITED-study
    • 21890335 10.1016/j.rmed.2011.08.010
    • Korn S, Buhl R. Efficacy of a fixed combination of ciclesonide and formoterol: the EXCITED-study. Respir Med. 2012;106(1):57-67.
    • (2012) Respir Med , vol.106 , Issue.1 , pp. 57-67
    • Korn, S.1    Buhl, R.2
  • 49
    • 84930479279 scopus 로고    scopus 로고
    • Pharmacology and therapeutics of bronchodilators
    • 22611179 1:CAS:528:DC%2BC3sXhslaksQ%3D%3D 10.1124/pr.111.004580
    • Cazzola M, Page CP, Calzetta L, Matera MG. Pharmacology and therapeutics of bronchodilators. Pharmacol Rev. 2012;64(3):450-504.
    • (2012) Pharmacol Rev , vol.64 , Issue.3 , pp. 450-504
    • Cazzola, M.1    Page, C.P.2    Calzetta, L.3    Matera, M.G.4
  • 50
    • 79953726304 scopus 로고    scopus 로고
    • Glucocorticosteroids: Current and future directions
    • 21198556 1:CAS:528:DC%2BC3MXls1GjtL4%3D 10.1111/j.1476-5381.2010.01199.x
    • Barnes PJ. Glucocorticosteroids: current and future directions. Br J Pharmacol. 2011;163(1):29-43.
    • (2011) Br J Pharmacol , vol.163 , Issue.1 , pp. 29-43
    • Barnes, P.J.1
  • 54
    • 0033864739 scopus 로고    scopus 로고
    • Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism
    • 10770286 1:CAS:528:DC%2BD3cXkvVygtrs%3D
    • Yasui K, Agematsu K, Shinozaki K, Hokibara S, Nagumo H, Nakazawa T, et al. Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism. J Leukoc Biol. 2000;67(4):529-35.
    • (2000) J Leukoc Biol , vol.67 , Issue.4 , pp. 529-535
    • Yasui, K.1    Agematsu, K.2    Shinozaki, K.3    Hokibara, S.4    Nagumo, H.5    Nakazawa, T.6
  • 56
    • 0242667861 scopus 로고    scopus 로고
    • Low-dose theophylline in childhood asthma: A placebo-controlled, double-blind study
    • DOI 10.1034/j.1399-3038.2003.00069.x
    • Suessmuth S, Freihorst J, Gappa M. Low-dose theophylline in childhood asthma: a placebo-controlled, double-blind study. Pediatr Allergy Immunol. 2003;14(5):394-400. (Pubitemid 37376973)
    • (2003) Pediatric Allergy and Immunology , vol.14 , Issue.5 , pp. 394-400
    • Suessmuth, S.1    Freihorst, J.2    Gappa, M.3
  • 57
    • 33749026661 scopus 로고    scopus 로고
    • A randomized open-label comparative study of montelukast versus theophylline added to inhaled corticosteroid in asthmatic children
    • DOI 10.2332/allergolint.55.287
    • Kondo N, Katsunuma T, Odajima Y, Morikawa A. A randomized open-label comparative study of montelukast versus theophylline added to inhaled corticosteroid in asthmatic children. Allergol Int. 2006;55(3):287-93. (Pubitemid 44444425)
    • (2006) Allergology International , vol.55 , Issue.3 , pp. 287-293
    • Kondo, N.1    Katsunuma, T.2    Odajima, Y.3    Morikawa, A.4
  • 58
    • 44049090276 scopus 로고    scopus 로고
    • Doxofylline: The next generation methylxanthine
    • DOI 10.1007/s12098-008-0054-1
    • Sankar J, Lodha R, Kabra SK. Doxofylline: The next generation methylxanthine. Indian J Pediatr. 2008;75(3):251-4. (Pubitemid 351712990)
    • (2008) Indian Journal of Pediatrics , vol.75 , Issue.3 , pp. 251-254
    • Sankar, J.1    Lodha, R.2    Kabra, S.K.3
  • 59
    • 83155173916 scopus 로고    scopus 로고
    • Macrolides in the treatment of asthma
    • 22112996 1:CAS:528:DC%2BC3MXhsFOgt7fF 10.1097/MCP.0b013e32834daff8
    • Good JT Jr, Rollins DR, Martin RJ. Macrolides in the treatment of asthma. Curr Opin Pulm Med. 2012;18(1):76-84.
    • (2012) Curr Opin Pulm Med , vol.18 , Issue.1 , pp. 76-84
    • Good, Jr.J.T.1    Rollins, D.R.2    Martin, R.J.3
  • 60
    • 0032015311 scopus 로고    scopus 로고
    • Erythromycin treatment in diffuse panbronchiolitis
    • Kudoh S. Erythromycin treatment in diffuse panbronchiolitis. Curr Opin Pulm Med. 1998;4(2):116-21. (Pubitemid 128354930)
    • (1998) Current Opinion in Pulmonary Medicine , vol.4 , Issue.2 , pp. 116-121
    • Kudoh, S.1
  • 61
    • 84865131777 scopus 로고    scopus 로고
    • Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis (EMBRACE): A randomised, double-blind, placebo-controlled trial
    • 22901887 1:CAS:528:DC%2BC38Xht1akt7vJ 10.1016/S0140-6736(12)60953-2
    • Wong C, Jayaram L, Karalus N, Eaton T, Tong C, Hockey H, et al. Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis (EMBRACE): a randomised, double-blind, placebo-controlled trial. Lancet. 2012;380(9842):660-7.
    • (2012) Lancet , vol.380 , Issue.9842 , pp. 660-667
    • Wong, C.1    Jayaram, L.2    Karalus, N.3    Eaton, T.4    Tong, C.5    Hockey, H.6
  • 63
    • 0037190575 scopus 로고    scopus 로고
    • Long term azithromycin in children with cystic fibrosis: A randomised, placebo-controlled crossover trial
    • DOI 10.1016/S0140-6736(02)11081-6
    • Equi A, Balfour-Lynn IM, Bush A, Rosenthal M. Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. Lancet. 2002;360(9338):978-84. (Pubitemid 35284109)
    • (2002) Lancet , vol.360 , Issue.9338 , pp. 978-984
    • Equi, A.1    Balfour-Lynn, I.M.2    Bush, A.3    Rosenthal, M.4
  • 64
    • 33749984264 scopus 로고    scopus 로고
    • Long term effects of azithromycin in patients with cystic fibrosis: A double blind, placebo controlled trial
    • DOI 10.1136/thx.2005.057950
    • Clement A, Tamalet A, Leroux E, Ravilly S, Fauroux B, Jais JP. Long term effects of azithromycin in patients with cystic fibrosis: a double blind, placebo controlled trial. Thorax. 2006;61(10):895-902. (Pubitemid 44570311)
    • (2006) Thorax , vol.61 , Issue.10 , pp. 895-902
    • Clement, A.1    Tamalet, A.2    Leroux, E.3    Ravilly, S.4    Fauroux, B.5    Jais, J.-P.6
  • 65
    • 84870767752 scopus 로고    scopus 로고
    • A retrospective analysis of the impact of azithromycin maintenance therapy on adults attending a UK cystic fibrosis clinic
    • Fleet JE, Guha K, Piper S, Banya W, Bilton D, Hodson ME. A retrospective analysis of the impact of azithromycin maintenance therapy on adults attending a UK cystic fibrosis clinic. J Cyst Fibrosis. 2013;12(1):49-53.
    • (2013) J Cyst Fibrosis , vol.12 , Issue.1 , pp. 49-53
    • Fleet, J.E.1    Guha, K.2    Piper, S.3    Banya, W.4    Bilton, D.5    Hodson, M.E.6
  • 67
    • 38348998987 scopus 로고    scopus 로고
    • Clarithromycin targets neutrophilic airway inflammation in refractory asthma
    • 17947611 1:CAS:528:DC%2BD1cXhvFGgt70%3D 10.1164/rccm.200707-1134OC
    • Simpson JL, Powell H, Boyle MJ, Scott RJ, Gibson PG. Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med. 2008;177(2):148-55.
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.2 , pp. 148-155
    • Simpson, J.L.1    Powell, H.2    Boyle, M.J.3    Scott, R.J.4    Gibson, P.G.5
  • 68
    • 34248399202 scopus 로고    scopus 로고
    • Azithromycin reduces bronchial hyperresponsiveness and neutrophilic airway inflammation in asthmatic children: A preliminary report
    • Piacentini GL, Peroni DG, Bodini A, Pigozzi R, Costella S, Loiacono A, et al. Azithromycin reduces bronchial hyperresponsiveness and neutrophilic airway inflammation in asthmatic children: a preliminary report. Allergy Asthma Proc. 2007;28(2):194-8.
    • (2007) Allergy Asthma Proc. , vol.28 , Issue.2 , pp. 194-198
    • Piacentini, G.L.1    Peroni, D.G.2    Bodini, A.3    Pigozzi, R.4    Costella, S.5    Loiacono, A.6
  • 69
    • 0025930313 scopus 로고
    • Benefits and complications of troleandomycin (TAO) in young children with steroid-dependent asthma
    • 1852515 1:STN:280:DyaK3MzgsV2lug%3D%3D 10.1002/ppul.1950100308
    • Flotte TR, Loughlin GM. Benefits and complications of troleandomycin (TAO) in young children with steroid-dependent asthma. Pediatr Pulmonol. 1991;10(3):178-82.
    • (1991) Pediatr Pulmonol , vol.10 , Issue.3 , pp. 178-182
    • Flotte, T.R.1    Loughlin, G.M.2
  • 70
    • 0025321036 scopus 로고
    • Effect of low-dose troleandomycin on glucocorticoid pharmacokinetics and airway hyperresponsiveness in severely asthmatic children
    • Ball BD, Hill MR, Brenner M, Sanks R, Szefler SJ. Effect of low-dose troleandomycin on glucocorticoid pharmacokinetics and airway hyperresponsiveness in severely asthmatic children. Ann Allergy. 1990;65(1):37-45. (Pubitemid 20233090)
    • (1990) Annals of Allergy , vol.65 , Issue.1 , pp. 37-45
    • Ball, B.D.1    Hill, M.R.2    Brennor, M.3    Sanks, R.4    Szefler, S.J.5
  • 72
    • 0032967254 scopus 로고    scopus 로고
    • Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers
    • Varis T, Kivisto KT, Backman JT, Neuvonen PJ. Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers. Pharmacol Toxicol. 1999;85(1):29-32. (Pubitemid 29291191)
    • (1999) Pharmacology and Toxicology , vol.85 , Issue.1 , pp. 29-32
    • Varis, T.1    Kivisto, K.T.2    Backman, J.T.3    Neuvonen, P.J.4
  • 73
    • 0036242542 scopus 로고    scopus 로고
    • Effect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthma
    • DOI 10.1081/JAS-120002199
    • Ekici A, Ekici M, Erdemoglu AK. Effect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthma. J Asthma. 2002;39(2):181-5. (Pubitemid 34464576)
    • (2002) Journal of Asthma , vol.39 , Issue.2 , pp. 181-185
    • Ekici, A.1    Ekici, M.2    Kemal Erdemoglu, A.3
  • 76
    • 0036279989 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: Effect of clarithromycin
    • DOI 10.1378/chest.121.6.1782
    • Kraft M, Cassell GH, Pak J, Martin RJ. Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin. Chest. 2002;121(6):1782-8. (Pubitemid 34634396)
    • (2002) Chest , vol.121 , Issue.6 , pp. 1782-1788
    • Kraft, M.1    Cassell, G.H.2    Pak, J.3    Martin, R.J.4
  • 77
    • 0034821548 scopus 로고    scopus 로고
    • Evaluation of blood vessels and edema in the airways of asthma patients: Regulation with clarithromycin treatment
    • DOI 10.1378/chest.120.2.416
    • Chu HW, Kraft M, Rex MD, Martin RJ. Evaluation of blood vessels and edema in the airways of asthma patients: regulation with clarithromycin treatment. Chest. 2001;120(2):416-22. (Pubitemid 32881256)
    • (2001) Chest , vol.120 , Issue.2 , pp. 416-422
    • Hong Wei Chu1    Kraft, M.2    Rex, M.D.3    Martin, R.J.4
  • 78
    • 79551495183 scopus 로고    scopus 로고
    • Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
    • 372-81.e1-3
    • Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol. 2011;127(2):372-81.e1-3.
    • (2011) J Allergy Clin Immunol. , vol.127 , Issue.2
    • Huang, Y.J.1    Nelson, C.E.2    Brodie, E.L.3    Desantis, T.Z.4    Baek, M.S.5    Liu, J.6
  • 79
    • 84865302911 scopus 로고    scopus 로고
    • Azithromycin and the risk of cardiovascular death
    • 2012 Aug 23;367(8):774-5; author reply 5
    • Pires dos Santos R, Kuchenbecker R. Azithromycin and the risk of cardiovascular death. N Engl J Med. 2012 Aug 23;367(8):774-5; author reply 5.
    • N Engl J Med.
    • Pires Dos Santos, R.1    Kuchenbecker, R.2
  • 80
    • 79953718767 scopus 로고    scopus 로고
    • Cytokine/anti-cytokine therapy - Novel treatments for asthma?
    • Hansbro PM, Kaiko GE, Foster PS. Cytokine/anti-cytokine therapy - novel treatments for asthma? Br J Pharmacol. 2011;163(1):81-95.
    • (2011) Br J Pharmacol , vol.163 , Issue.1 , pp. 81-95
    • Hansbro, P.M.1    Kaiko, G.E.2    Foster, P.S.3
  • 81
    • 77951885204 scopus 로고    scopus 로고
    • TH17 cells in asthma and COPD
    • 20148686 1:CAS:528:DC%2BC3cXktFKktLs%3D 10.1146/annurev-physiol-021909- 135926
    • Alcorn JF, Crowe CR, Kolls JK. TH17 cells in asthma and COPD. Annu Rev Physiol. 2010;72:495-516.
    • (2010) Annu Rev Physiol , vol.72 , pp. 495-516
    • Alcorn, J.F.1    Crowe, C.R.2    Kolls, J.K.3
  • 82
    • 58749091674 scopus 로고    scopus 로고
    • Untangling the complex web of IL-4- and IL-13-mediated signaling pathways
    • Wills-Karp M, Finkelman FD. Untangling the complex web of IL-4- and IL-13-mediated signaling pathways. Sci Signal. 2008;1(51):pe55.
    • (2008) Sci Signal. , vol.1 , Issue.51
    • Wills-Karp, M.1    Finkelman, F.D.2
  • 84
    • 80053085384 scopus 로고    scopus 로고
    • Asthma phenotypes and interleukin-13-moving closer to personalized medicine
    • 21879891 1:CAS:528:DC%2BC3MXht1WqtrfO 10.1056/NEJMe1108666
    • Kraft M. Asthma phenotypes and interleukin-13-moving closer to personalized medicine. N Engl J Med. 2011;365(12):1141-4.
    • (2011) N Engl J Med , vol.365 , Issue.12 , pp. 1141-1144
    • Kraft, M.1
  • 85
    • 77956289251 scopus 로고    scopus 로고
    • Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma
    • 1:CAS:528:DC%2BC3cXhtVCkt77L 10.1073/pnas.1009426107 20660732
    • Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff PG, Hou L, et al. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci USA. 2010;107(32):14170-5.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.32 , pp. 14170-14175
    • Sidhu, S.S.1    Yuan, S.2    Innes, A.L.3    Kerr, S.4    Woodruff, P.G.5    Hou, L.6
  • 86
    • 84855171665 scopus 로고    scopus 로고
    • Lebrikizumab treatment in adults with asthma
    • author reply 3-4
    • Zeskind B. Lebrikizumab treatment in adults with asthma. N Engl J Med. 2011;365(25):2432; author reply 3-4.
    • (2011) N Engl J Med. , vol.365 , Issue.25 , pp. 2432
    • Zeskind, B.1
  • 87
    • 35348909044 scopus 로고    scopus 로고
    • Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies
    • DOI 10.1016/S0140-6736(07)61600-6, PII S0140673607616006
    • Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet. 2007;370(9596):1422-31. (Pubitemid 47576168)
    • (2007) Lancet , vol.370 , Issue.9596 , pp. 1422-1431
    • Wenzel, S.1    Wilbraham, D.2    Fuller, R.3    Getz, E.B.4    Longphre, M.5
  • 88
    • 84864445917 scopus 로고    scopus 로고
    • IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor alpha antagonist
    • 516-22.e4
    • Slager RE, Otulana BA, Hawkins GA, Yen YP, Peters SP, Wenzel SE, et al. IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor alpha antagonist. J Allergy Clin Immunol. 2012;130(2):516-22.e4.
    • (2012) J Allergy Clin Immunol. , vol.130 , Issue.2
    • Slager, R.E.1    Otulana, B.A.2    Hawkins, G.A.3    Yen, Y.P.4    Peters, S.P.5    Wenzel, S.E.6
  • 89
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • 19264686 1:CAS:528:DC%2BD1MXislOlsLs%3D 10.1056/NEJMoa0808991
    • Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med. 2009;360(10):973-84.
    • (2009) N Engl J Med , vol.360 , Issue.10 , pp. 973-984
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3    Gupta, S.4    Monteiro, W.5    Sousa, A.6
  • 90
    • 61849155730 scopus 로고    scopus 로고
    • Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
    • 19264687 1:CAS:528:DC%2BD1MXislOlsLg%3D 10.1056/NEJMoa0805435
    • Nair P, Pizzichini MM, Kjarsgaard M, Inman MD, Efthimiadis A, Pizzichini E, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med. 2009;360(10):985-93.
    • (2009) N Engl J Med , vol.360 , Issue.10 , pp. 985-993
    • Nair, P.1    Pizzichini, M.M.2    Kjarsgaard, M.3    Inman, M.D.4    Efthimiadis, A.5    Pizzichini, E.6
  • 91
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
    • 22901886 1:CAS:528:DC%2BC38Xht1aksLfE 10.1016/S0140-6736(12)60988-X
    • Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet. 2012;380(9842):651-9.
    • (2012) Lancet , vol.380 , Issue.9842 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3    Bleecker, E.R.4    Buhl, R.5    Keene, O.N.6
  • 92
    • 84866357321 scopus 로고    scopus 로고
    • Effect of Vitamin D and inhaled corticosteroid treatment on lung function in children
    • 22798322 1:CAS:528:DC%2BC38Xhs1emur7M 10.1164/rccm.201202-0351OC
    • Wu AC, Tantisira K, Li L, Fuhlbrigge AL, Weiss ST, Litonjua A. Effect of Vitamin D and inhaled corticosteroid treatment on lung function in children. Am J Respir Crit Care Med. 2012;186(6):508-13.
    • (2012) Am J Respir Crit Care Med , vol.186 , Issue.6 , pp. 508-513
    • Wu, A.C.1    Tantisira, K.2    Li, L.3    Fuhlbrigge, A.L.4    Weiss, S.T.5    Litonjua, A.6
  • 93
    • 84866403448 scopus 로고    scopus 로고
    • Is the best offense a good D-fense?: Should we use Vitamin D as adjunctive therapy for asthma?
    • 22984020 1:CAS:528:DC%2BC38Xhs1emtbfE 10.1164/rccm.201207-1295ED
    • Kreindler JL. Is the best offense a good D-fense?: Should we use Vitamin D as adjunctive therapy for asthma? Am J Respir Crit Care Med. 2012;186(6):470-2.
    • (2012) Am J Respir Crit Care Med , vol.186 , Issue.6 , pp. 470-472
    • Kreindler, J.L.1
  • 94
    • 84455204862 scopus 로고    scopus 로고
    • Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma
    • 21908411 1:CAS:528:DC%2BC38XhtV2gtr4%3D 10.1164/rccm.201107-1239OC
    • Gupta A, Sjoukes A, Richards D, Banya W, Hawrylowicz C, Bush A, et al. Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med. 2011;184(12):1342-9.
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.12 , pp. 1342-1349
    • Gupta, A.1    Sjoukes, A.2    Richards, D.3    Banya, W.4    Hawrylowicz, C.5    Bush, A.6
  • 95
    • 76249105902 scopus 로고    scopus 로고
    • Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state
    • 20008294 1:CAS:528:DC%2BC3cXhslCkuw%3D%3D 10.4049/jimmunol.0902840
    • Hansdottir S, Monick MM, Lovan N, Powers L, Gerke A, Hunninghake GW. Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. J Immunol. 2010;184(2):965-74.
    • (2010) J Immunol , vol.184 , Issue.2 , pp. 965-974
    • Hansdottir, S.1    Monick, M.M.2    Lovan, N.3    Powers, L.4    Gerke, A.5    Hunninghake, G.W.6
  • 96
    • 50249173892 scopus 로고    scopus 로고
    • Vitamin D and glucocorticoids differentially modulate chemokine expression in human airway smooth muscle cells
    • 18552877 1:CAS:528:DC%2BD1cXhtVagsLfN 10.1038/bjp.2008.232
    • Banerjee A, Damera G, Bhandare R, Gu S, Lopez-Boado Y, Panettieri R Jr, et al. Vitamin D and glucocorticoids differentially modulate chemokine expression in human airway smooth muscle cells. Br J Pharmacol. 2008;155(1):84-92.
    • (2008) Br J Pharmacol , vol.155 , Issue.1 , pp. 84-92
    • Banerjee, A.1    Damera, G.2    Bhandare, R.3    Gu, S.4    Lopez-Boado, Y.5    Panettieri, Jr.R.6
  • 98
    • 84866490369 scopus 로고    scopus 로고
    • The rising cost of vitamin D testing in Australia: Time to establish guidelines for testing
    • 22794049 10.5694/mja12.10561
    • Bilinski KL, Boyages SC. The rising cost of vitamin D testing in Australia: time to establish guidelines for testing. Med J Aust. 2012;197(2):90.
    • (2012) Med J Aust , vol.197 , Issue.2 , pp. 90
    • Bilinski, K.L.1    Boyages, S.C.2
  • 99
    • 84879418170 scopus 로고    scopus 로고
    • Hypovitaminosis D a consequence rather than cause of disease?
    • [Epub ahead of print]
    • Shee C. Is hypovitaminosis D a consequence rather than cause of disease? Thorax. 2013 [Epub ahead of print].
    • (2013) Thorax
    • Shee, C.1
  • 102
    • 70350458755 scopus 로고    scopus 로고
    • The prevalence of nonadherence in difficult asthma
    • 19644048 10.1164/rccm.200902-0166OC
    • Gamble J, Stevenson M, McClean E, Heaney LG. The prevalence of nonadherence in difficult asthma. Am J Respir Crit Care Med. 2009;180(9):817-22.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.9 , pp. 817-822
    • Gamble, J.1    Stevenson, M.2    McClean, E.3    Heaney, L.G.4
  • 104
    • 0036637274 scopus 로고    scopus 로고
    • Relationship of adherence to pediatric asthma morbidity among inner-city children
    • 12093987 10.1542/peds.110.1.e6
    • Bauman LJ, Wright E, Leickly FE, Crain E, Kruszon-Moran D, Wade SL, et al. Relationship of adherence to pediatric asthma morbidity among inner-city children. Pediatrics. 2002;110(1 Pt 1):e6.
    • (2002) Pediatrics , vol.110 , Issue.1 PART 1 , pp. 6
    • Bauman, L.J.1    Wright, E.2    Leickly, F.E.3    Crain, E.4    Kruszon-Moran, D.5    Wade, S.L.6
  • 105
    • 0036286739 scopus 로고    scopus 로고
    • Overcoming barriers to nonadherence in asthma treatment
    • 12063512 10.1067/mai.2002.124570
    • Bender BG. Overcoming barriers to nonadherence in asthma treatment. J Allergy Clin Immunol. 2002;109(6 Suppl):S554-9.
    • (2002) J Allergy Clin Immunol , vol.109 , Issue.6 SUPPL.
    • Bender, B.G.1
  • 106
    • 38049074372 scopus 로고    scopus 로고
    • Dry powder inhalers: Which factors determine the frequency of handling errors?
    • 17911976 10.1159/000109374
    • Wieshammer S, Dreyhaupt J. Dry powder inhalers: which factors determine the frequency of handling errors? Respiration. 2008;75(1):18-25.
    • (2008) Respiration , vol.75 , Issue.1 , pp. 18-25
    • Wieshammer, S.1    Dreyhaupt, J.2
  • 107
    • 82255176840 scopus 로고    scopus 로고
    • Medication use in children with asthma: Not a child size problem
    • 22013989 10.3109/02770903.2011.624234
    • Grover C, Armour C, Van Asperen PP, Moles R, Saini B. Medication use in children with asthma: not a child size problem. J Asthma. 2011;48(10):1085-103.
    • (2011) J Asthma , vol.48 , Issue.10 , pp. 1085-1103
    • Grover, C.1    Armour, C.2    Van Asperen, P.P.3    Moles, R.4    Saini, B.5
  • 108
    • 77952695527 scopus 로고    scopus 로고
    • The role of viruses in acute exacerbations of asthma
    • quiz 88-9
    • Jackson DJ, Johnston SL. The role of viruses in acute exacerbations of asthma. J Allergy Clin Immunol. 2010;125(6):1178-87; quiz 88-9.
    • (2010) J Allergy Clin Immunol. , vol.125 , Issue.6 , pp. 1178-1187
    • Jackson, D.J.1    Johnston, S.L.2
  • 109
    • 77952744331 scopus 로고    scopus 로고
    • Do early-life viral infections cause asthma?
    • 20304476 1:CAS:528:DC%2BC3cXhtVaitL3O 10.1016/j.jaci.2010.01.024
    • Sly PD, Kusel M, Holt PG. Do early-life viral infections cause asthma? J Allergy Clin Immunol. 2010;125(6):1202-5.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.6 , pp. 1202-1205
    • Sly, P.D.1    Kusel, M.2    Holt, P.G.3
  • 110
    • 0141953261 scopus 로고    scopus 로고
    • Association between antenatal cytokine production and the development of atopy and asthma at age 6 years
    • DOI 10.1016/S0140-6736(03)14542-4
    • Macaubas C, de Klerk NH, Holt BJ, Wee C, Kendall G, Firth M, et al. Association between antenatal cytokine production and the development of atopy and asthma at age 6 years. Lancet. 2003;362(9391):1192-7. (Pubitemid 37255345)
    • (2003) Lancet , vol.362 , Issue.9391 , pp. 1192-1197
    • Macaubas, C.1    De Klerk, N.H.2    Holt, B.J.3    Wee, C.4    Kendall, G.5    Firth, M.6    Sly, P.D.7    Holt, P.G.8
  • 111
    • 34247500952 scopus 로고    scopus 로고
    • Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma
    • DOI 10.1016/j.jaci.2006.12.669, PII S0091674907002382
    • Kusel MM, de Klerk NH, Kebadze T, Vohma V, Holt PG, Johnston SL, et al. Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma. J Allergy Clin Immunol. 2007;119(5):1105-10. (Pubitemid 46654175)
    • (2007) Journal of Allergy and Clinical Immunology , vol.119 , Issue.5 , pp. 1105-1110
    • Kusel, M.M.H.1    De Klerk, N.H.2    Kebadze, T.3    Vohma, V.4    Holt, P.G.5    Johnston, S.L.6    Sly, P.D.7
  • 112
    • 0029658108 scopus 로고    scopus 로고
    • 4 receptor antagonist, LY293111, on allergen induced responses in asthma
    • Evans DJ, Barnes PJ, Spaethe SM, van Alstyne EL, Mitchell MI, O'Connor BJ. Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma. Thorax. 1996;51(12):1178-84. (Pubitemid 26413134)
    • (1996) Thorax , vol.51 , Issue.12 , pp. 1178-1184
    • Evans, D.J.1    Barnes, P.J.2    Spaethe, S.M.3    Van Alstyne, E.L.4    Mitchell, M.I.5    O'Connor, B.J.6
  • 113
    • 77952313992 scopus 로고    scopus 로고
    • Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness
    • 20110560 1:CAS:528:DC%2BC3cXhtFahsb%2FN 10.1164/rccm.200807-1158OC
    • Rao NL, Riley JP, Banie H, Xue X, Sun B, Crawford S, et al. Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness. Am J Respir Crit Care Med. 2010;181(9):899-907.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.9 , pp. 899-907
    • Rao, N.L.1    Riley, J.P.2    Banie, H.3    Xue, X.4    Sun, B.5    Crawford, S.6
  • 114
    • 73649118166 scopus 로고    scopus 로고
    • Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases
    • 20021282 1:CAS:528:DC%2BD1MXhs1SmsbvN 10.1517/13543770903463905
    • Magrioti V, Kokotos G. Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases. Expert Opin Ther Pat. 2010;20(1):1-18.
    • (2010) Expert Opin Ther Pat , vol.20 , Issue.1 , pp. 1-18
    • Magrioti, V.1    Kokotos, G.2
  • 115
    • 69549130721 scopus 로고    scopus 로고
    • 5-Oxo-ETE and the OXE receptor
    • 19450703 1:CAS:528:DC%2BD1MXhtV2lu7nE 10.1016/j.prostaglandins.2009.05. 002
    • Grant GE, Rokach J, Powell WS. 5-Oxo-ETE and the OXE receptor. Prostaglandins Other Lipid Mediat. 2009;89(3-4):98-104.
    • (2009) Prostaglandins Other Lipid Mediat , vol.89 , Issue.3-4 , pp. 98-104
    • Grant, G.E.1    Rokach, J.2    Powell, W.S.3
  • 116
    • 79551511756 scopus 로고    scopus 로고
    • Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program
    • Balzar S, Fajt ML, Comhair SA, Erzurum SC, Bleecker E, Busse WW, et al. Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. Am J Respir Crit Care Med. 2011;183(3):299-309.
    • (2011) Am J Respir Crit Care Med. , vol.183 , Issue.3 , pp. 299-309
    • Balzar, S.1    Fajt, M.L.2    Comhair, S.A.3    Erzurum, S.C.4    Bleecker, E.5    Busse, W.W.6
  • 117
    • 84655167630 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma
    • 21762224 1:CAS:528:DC%2BC38XisVKisrY%3D 10.1111/j.1365-2222.2011.03813.x
    • Barnes N, Pavord I, Chuchalin A, Bell J, Hunter M, Lewis T, et al. A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma. Clin Exp Allergy. 2012;42(1):38-48.
    • (2012) Clin Exp Allergy , vol.42 , Issue.1 , pp. 38-48
    • Barnes, N.1    Pavord, I.2    Chuchalin, A.3    Bell, J.4    Hunter, M.5    Lewis, T.6
  • 118
    • 71749095907 scopus 로고    scopus 로고
    • Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis
    • 942-8.e1-9
    • Philip G, van Adelsberg J, Loeys T, Liu N, Wong P, Lai E, et al. Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis. J Allergy Clin Immunol. 2009;124(5):942-8.e1-9.
    • (2009) J Allergy Clin Immunol. , vol.124 , Issue.5
    • Philip, G.1    Van Adelsberg, J.2    Loeys, T.3    Liu, N.4    Wong, P.5    Lai, E.6
  • 119
    • 79959335782 scopus 로고    scopus 로고
    • Long-term monotherapy with suplatast tosilate in patients with mild atopic asthma: A pilot comparison with low-dose inhaled fluticasone
    • 21980828 1:CAS:528:DC%2BC3MXhsFGjsrvJ
    • Shiga M, Horiguchi T, Kondo R, Miyazaki J, Hirose M, Otake Y, et al. Long-term monotherapy with suplatast tosilate in patients with mild atopic asthma: a pilot comparison with low-dose inhaled fluticasone. Asian Pac J Allergy Immunol. 2011;29(2):134-42.
    • (2011) Asian Pac J Allergy Immunol , vol.29 , Issue.2 , pp. 134-142
    • Shiga, M.1    Horiguchi, T.2    Kondo, R.3    Miyazaki, J.4    Hirose, M.5    Otake, Y.6
  • 120
    • 70450162956 scopus 로고    scopus 로고
    • Effect of suplatast tosilate on antileukotriene non-responders with mild-to-moderate persistent asthma
    • 19542765 1:CAS:528:DC%2BD1MXhtlWhsL7L 10.2332/allergolint.08-OA-0068
    • Wada M, Nagata S, Kudo T, Shimizu T, Yamashiro Y. Effect of suplatast tosilate on antileukotriene non-responders with mild-to-moderate persistent asthma. Allergol Int. 2009;58(3):389-93.
    • (2009) Allergol Int , vol.58 , Issue.3 , pp. 389-393
    • Wada, M.1    Nagata, S.2    Kudo, T.3    Shimizu, T.4    Yamashiro, Y.5
  • 121
    • 78049258314 scopus 로고    scopus 로고
    • Relationship between the benefits of suplatast tosilate, a Th2 cytokine inhibitor, and gene polymorphisms in children with bronchial asthma
    • 22993628 1:CAS:528:DC%2BC3cXhsVejtLzL
    • Matsui E, Shinoda S, Fukutomi O, Kaneko H, Fukao T, Kondo N. Relationship between the benefits of suplatast tosilate, a Th2 cytokine inhibitor, and gene polymorphisms in children with bronchial asthma. Exp Ther Med. 2010;1(6):977-82.
    • (2010) Exp Ther Med , vol.1 , Issue.6 , pp. 977-982
    • Matsui, E.1    Shinoda, S.2    Fukutomi, O.3    Kaneko, H.4    Fukao, T.5    Kondo, N.6
  • 122
    • 81455155725 scopus 로고    scopus 로고
    • Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
    • 21852542 1:CAS:528:DC%2BC3MXhs1ejsLnL 10.1164/rccm.201103-0396OC
    • Castro M, Mathur S, Hargreave F, Boulet LP, Xie F, Young J, et al. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med. 2011;184(10):1125-32.
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.10 , pp. 1125-1132
    • Castro, M.1    Mathur, S.2    Hargreave, F.3    Boulet, L.P.4    Xie, F.5    Young, J.6
  • 123
    • 77952683218 scopus 로고    scopus 로고
    • Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase i study of subjects with mild asthma
    • 1237-44.e2
    • Busse WW, Katial R, Gossage D, Sari S, Wang B, Kolbeck R, et al. Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma. J Allergy Clin Immunol. 2010;125(6):1237-44.e2.
    • (2010) J Allergy Clin Immunol. , vol.125 , Issue.6
    • Busse, W.W.1    Katial, R.2    Gossage, D.3    Sari, S.4    Wang, B.5    Kolbeck, R.6
  • 124
    • 84873389433 scopus 로고    scopus 로고
    • A phase 2 placebo-controlled study of tralokinumab in moderate-to-severe asthma
    • Piper E, Brightling C, Niven R, Oh C, Faggioni R, Poon K, et al. A phase 2 placebo-controlled study of tralokinumab in moderate-to-severe asthma. Eur Respir J. 2013;41(2):330-8.
    • (2013) Eur Respir J. , vol.41 , Issue.2 , pp. 330-338
    • Piper, E.1    Brightling, C.2    Niven, R.3    Oh, C.4    Faggioni, R.5    Poon, K.6
  • 125
    • 77953039047 scopus 로고    scopus 로고
    • A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
    • 20056900 1:CAS:528:DC%2BC3cXhtFahsb7O 10.1164/rccm.200909-1448OC
    • Corren J, Busse W, Meltzer EO, Mansfield L, Bensch G, Fahrenholz J, et al. A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med. 2010;181(8):788-96.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.8 , pp. 788-796
    • Corren, J.1    Busse, W.2    Meltzer, E.O.3    Mansfield, L.4    Bensch, G.5    Fahrenholz, J.6
  • 128
    • 62549084077 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma
    • 19136369 1:CAS:528:DC%2BD1MXkslWnsLo%3D 10.1164/rccm.200809-1512OC
    • Wenzel SE, Barnes PJ, Bleecker ER, Bousquet J, Busse W, Dahlen SE, et al. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med. 2009;179(7):549-58.
    • (2009) Am J Respir Crit Care Med , vol.179 , Issue.7 , pp. 549-558
    • Wenzel, S.E.1    Barnes, P.J.2    Bleecker, E.R.3    Bousquet, J.4    Busse, W.5    Dahlen, S.E.6
  • 129
    • 70349658639 scopus 로고    scopus 로고
    • Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT
    • 19789626 10.1371/journal.pone.0007258 1:CAS:528:DC%2BD1MXht1altLjO
    • Dubreuil P, Letard S, Ciufolini M, Gros L, Humbert M, Casteran N, et al. Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. PLoS ONE. 2009;4(9):e7258.
    • (2009) PLoS ONE , vol.4 , Issue.9 , pp. 7258
    • Dubreuil, P.1    Letard, S.2    Ciufolini, M.3    Gros, L.4    Humbert, M.5    Casteran, N.6
  • 130
    • 67650314629 scopus 로고    scopus 로고
    • Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics
    • 19614621 1:CAS:528:DC%2BD1MXhtVWjtL3P 10.1111/j.1398-9995.2009.02122.x
    • Humbert M, de Blay F, Garcia G, Prud'homme A, Leroyer C, Magnan A, et al. Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics. Allergy. 2009;64(8):1194-201.
    • (2009) Allergy , vol.64 , Issue.8 , pp. 1194-1201
    • Humbert, M.1    De Blay, F.2    Garcia, G.3    Prud'Homme, A.4    Leroyer, C.5    Magnan, A.6
  • 131
    • 77957768543 scopus 로고    scopus 로고
    • Tiotropium bromide step-up therapy for adults with uncontrolled asthma
    • 20979471 1:CAS:528:DC%2BC3cXhtlGrt73P 10.1056/NEJMoa1008770
    • Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010;363(18):1715-26.
    • (2010) N Engl J Med , vol.363 , Issue.18 , pp. 1715-1726
    • Peters, S.P.1    Kunselman, S.J.2    Icitovic, N.3    Moore, W.C.4    Pascual, R.5    Ameredes, B.T.6
  • 132
    • 79960973276 scopus 로고    scopus 로고
    • Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma
    • 21807250 1:CAS:528:DC%2BC3MXpsFKmsrg%3D 10.1016/j.jaci.2011.06.004
    • Bateman ED, Kornmann O, Schmidt P, Pivovarova A, Engel M, Fabbri LM. Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma. J Allergy Clin Immunol. 2011;128(2):315-22.
    • (2011) J Allergy Clin Immunol , vol.128 , Issue.2 , pp. 315-322
    • Bateman, E.D.1    Kornmann, O.2    Schmidt, P.3    Pivovarova, A.4    Engel, M.5    Fabbri, L.M.6
  • 133
    • 81355154616 scopus 로고    scopus 로고
    • Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects
    • 22029856 1:CAS:528:DC%2BC3MXhs1ensLjJ 10.1186/1465-9921-12-140
    • Gauvreau GM, Boulet LP, Schmid-Wirlitsch C, Cote J, Duong M, Killian KJ, et al. Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects. Respir Res. 2011;12:140.
    • (2011) Respir Res , vol.12 , pp. 140
    • Gauvreau, G.M.1    Boulet, L.P.2    Schmid-Wirlitsch, C.3    Cote, J.4    Duong, M.5    Killian, K.J.6
  • 134
    • 84862290893 scopus 로고    scopus 로고
    • Selective PDE inhibitors as novel treatments for respiratory diseases
    • 22497841 1:CAS:528:DC%2BC38Xltl2kurg%3D 10.1016/j.coph.2012.02.016
    • Page CP, Spina D. Selective PDE inhibitors as novel treatments for respiratory diseases. Curr Opin Pharmacol. 2012;12(3):275-86.
    • (2012) Curr Opin Pharmacol , vol.12 , Issue.3 , pp. 275-286
    • Page, C.P.1    Spina, D.2
  • 135
    • 77957788255 scopus 로고    scopus 로고
    • Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase
    • 754-62.e1
    • Maneechotesuwan K, Ekjiratrakul W, Kasetsinsombat K, Wongkajornsilp A, Barnes PJ. Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase. J Allergy Clin Immunol. 2010;126(4):754-62.e1.
    • (2010) J Allergy Clin Immunol. , vol.126 , Issue.4
    • Maneechotesuwan, K.1    Ekjiratrakul, W.2    Kasetsinsombat, K.3    Wongkajornsilp, A.4    Barnes, P.J.5
  • 136
    • 84869789379 scopus 로고    scopus 로고
    • Evaluation of atorvastatin for the treatment of patients with asthma: A double-blind randomized clinical trial
    • 22950035 1:CAS:528:DC%2BC38XhsVCrtbfJ 10.4168/aair.2012.4.5.290
    • Moini A, Azimi G, Farivar A. Evaluation of atorvastatin for the treatment of patients with asthma: a double-blind randomized clinical trial. Allergy Asthma Immunol Res. 2012;4(5):290-4.
    • (2012) Allergy Asthma Immunol Res , vol.4 , Issue.5 , pp. 290-294
    • Moini, A.1    Azimi, G.2    Farivar, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.