Leukotriene A4 hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness

American Journal of Respiratory and Critical Care Medicine

Volumn 181, Issue 9, 2010, Pages 899-907

  Rao, Navin L ^a   Riley, Jason P ^a   Banie, Homayon ^a   Xue, Xiaohua ^a   Sun, Binggang ^a   Crawford, Shelby ^a   Lundeen, Katherine A ^a   Yu, Fuqu ^a   Karlsson, Lars ^a   Fourie, Anne M ^a   Dunford, Paul J ^a  

^a PharMingen   (United States)

Author keywords

Dendritic cells; Leukotriene A4 hydrolase; Leukotriene B4; Lung function; T cells

Indexed keywords

CYTOKINE; ENZYME INHIBITOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; JNJ 26993135; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE A4 HYDROLASE INHIBITOR; LEUKOTRIENE B4; LIPOXIN A; MUCIN; UNCLASSIFIED DRUG; EPOXIDE HYDROLASE; OVALBUMIN;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; MAST CELL; MOUSE; NONHUMAN; OSCILLATION; PNEUMONIA; PRIORITY JOURNAL; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; BLOOD; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; IMMUNOLOGY; LUNG LAVAGE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CYTOKINES; EPOXIDE HYDROLASES; IMMUNOGLOBULIN E; LEUKOTRIENE B4; MAST CELLS; MICE; MICE, INBRED BALB C; MUCINS; OVALBUMIN;

EID: 77952313992     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200807-1158OC     Document Type: Article

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