Do early-life viral infections cause asthma?

Journal of Allergy and Clinical Immunology

Volumn 125, Issue 6, 2010, Pages 1202-1205

  Sly, Peter D ^a   Kusel, Merci ^a   Holt, Patrick G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Allergic sensitization; human rhinovirus; IgE; respiratory syncytial virus; T cells; wheeze

Indexed keywords

PALIVIZUMAB; PREDNISOLONE; RESPIRATORY SYNCYTIAL VIRUS VACCINE;

ARTICLE; ASTHMA; ATOPY; BRONCHIOLITIS; CHILDHOOD; CLINICAL TRIAL; DISEASE ASSOCIATION; DISEASE EXACERBATION; EPIGENETICS; HOST SUSCEPTIBILITY; HUMAN; IMMUNE RESPONSE; LOWER RESPIRATORY TRACT INFECTION; MUCOSAL IMMUNITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RHINOVIRUS INFECTION; RISK FACTOR; SENSITIZATION; VIRAL RESPIRATORY TRACT INFECTION; WHEEZING;

AGE FACTORS; AGE OF ONSET; ASTHMA; CHILD; HUMANS; PICORNAVIRIDAE INFECTIONS; RESPIRATORY MUCOSA; RESPIRATORY SOUNDS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RHINOVIRUS; RISK FACTORS;

EID: 77952744331     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.01.024     Document Type: Article

References (20)

1. Sigurs N., Bjarnason R., Sigurbergsson F., and Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med 161 (2000) 1501-1507
2. Stern D.A., Morgan W.J., Halonen M., Wright A.L., and Martinez F.D. Wheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort study. Lancet 372 (2008) 1058-1064
3. Papadopoulos N.G., and Kalobatsou A. Respiratory viruses in childhood asthma. Curr Opin Allergy Clin Immunol 7 (2007) 91-95
4. Sly P.D., Boner A.L., Bjorksten B., Bush A., Custovic A., Eigenmann P.A., et al. Early identification of atopy in the prediction of persistent asthma in children. Lancet 372 (2008) 1100-1106
5. Gern J.E. Rhinovirus and the initiation of asthma. Curr Opin Allergy Clin Immunol 9 (2009) 73-78
6. Jackson D.J., Gangnon R.E., Evans M.D., Roberg K.A., Anderson E.L., Pappas T.E., et al. Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am J Respir Crit Care Med 178 (2008) 667-672
7. Kusel M.M.H., de Klerk N.H., Kebadze T., Vohma V., Holt P.G., Johnston S.L., et al. Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma. J Allergy Clin Immunol 119 (2007) 1105-1110
8. Holt P.G., Upham J.W., and Sly P.D. Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies. J Allergy Clin Immunol 116 (2005) 16-24
9. Zhang G., Rowe J., Kusel M., Bosco A., McKenna K., de Klerk N., et al. IL-10:IL-5 responses at birth predict risk for respiratory infections in atopic family history positive children. Am J Respir Crit Care Med 179 (2009) 205-211
10. Bartlett N.W., McLean G.R., Chang Y.S., and Johnston S.L. Genetics and epidemiology: asthma and infection. Curr Opin Allergy Clin Immunol 9 (2009) 395-400
11. Frolich A., Kisielow J., Schmitz I., Freigang S., Shamshiev A., Weber J., et al. IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 324 (2009) 1576-1580
12. Adcock I.M., Tsaprouni L., Bhavsar P., and Ito K. Epigenetic regulation of airway inflammation. Curr Opin Immunol 19 (2007) 694-700
13. White G.P., Watt P., Holt B., and Holt P. Differential patterns of methylation of the IFNg promoter at CpG and non-CpG sites underlie the differences in the IFNg gene expression between human neonatal and adult CD45RO- T-cells. J Immunol 168 (2002) 2820-2827
14. White G.P., Hollams E.M., Yerkovich S.T., Bosco A., Holt B.J., Bassami M.R., et al. CpG methylation patterns in the IFN γ promoter in naive T cells: variations during Th1 and Th2 differentiation and between atopics and non-atopics. Pediatr Allergy Immunol 17 (2006) 557-564
15. Thomsen S.F., van der Sluis S., Stensballe L.G., Posthuma D., Skytthe A., Kyvik K.O., et al. Exploring the association between severe respiratory syncytial virus infection and asthma: a registry-based twin study. Am J Respir Crit Care Med 179 (2009) 1091-1097
16. Khaitov M.R., Laza-Stanca V., Edwards M.R., Walton R.P., Rohde G., Contoli M., et al. Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells. Allergy 64 (2009) 375-386
17. Wark P.A., Johnston S.L., Bucchieri F., Powell R., Puddicombe S., Laza-Stanca V., et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 201 (2005) 937-947
18. Contoli M., Message S.D., Laza-Stanca V., Edwards M.R., Wark P.A., Bartlett N.W., et al. Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 12 (2006) 1023-1026
19. Martinez F.D. The connection between early life wheezing and subsequent asthma: the viral march. Allergol Immunopathol (Madr) 37 (2009) 249-251
20. Subrata L.S., Bizzintino J., Mamessier E., Bosco A., McKenna K.L., Wikstrom M.E., et al. Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children. J Immunol 183 (2009) 2793-2800