Prevention by theophylline of beta-2-receptor down regulation in healthy subjects

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 25, Issue 3-4, 2000, Pages 179-188

  Derks, Michiel G M ^a   Koopmans, Richard P ^a   Oosterhoff, Els ^a   Van Boxtel, Chris J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Beta 2 agonist; Healthy volunteer; In vivo; PK PD modelling; Receptor down regulation; Theophylline

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; PHOSPHODIESTERASE INHIBITOR; PLACEBO; TERBUTALINE; THEOPHYLLINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; EOSINOPHIL; HUMAN; HYPOKALEMIA; LEUKOPENIA; MALE; PHARMACODYNAMICS; RANDOMIZED CONTROLLED TRIAL; RECEPTOR DOWN REGULATION; SLOW RELEASE FORMULATION;

CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DOWN-REGULATION; EOSINOPHILS; HUMANS; POTASSIUM; RECEPTORS, ADRENERGIC, BETA-2; TERBUTALINE; THEOPHYLLINE;

EID: 0034438859     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03192311     Document Type: Article

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