Frequency of thiopurine S-methyltransferase mutant alleles in indigenous and admixed Guatemalan patients with acute lymphoblastic leukemia

Medical Oncology

Volumn 30, Issue 1, 2013, Pages

  Garrido, Claudia ^a   Santizo, Veronica Giron ^a   Müllers, Petra ^a   Soriano, Daphney Rigaud ^a   Avila, Giovana Bendfeldt ^a,b   Dean, Michael ^b   Jimenez Morales, Silvia ^b,c  

^a Unidad Nacional de Oncologia Pediatrica   (Guatemala)

^b NATIONAL CANCER INSTITUTE   (United States)

^c INSTITUTO NACIONAL DE MEDICINA GENÓMICA   (Mexico)

Author keywords

Childhood acute lymphoblastic leukemia; Ethnic groups; Guatemala; Thiopurine therapy; TPMT gene

Indexed keywords

MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE; METHYLTRANSFERASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; ETHNIC DIFFERENCE; FEMALE; FLUORESCENCE ANALYSIS; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC VARIABILITY; GENOTYPE; GUATEMALA; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TREATMENT RESPONSE; ALLELE; CHILD; GENETICS; MUTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; ALLELES; CHILD; FEMALE; GENOTYPE; GUATEMALA; HUMANS; MALE; METHYLTRANSFERASES; MUTATION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MLCS; MLOWN;

EID: 84880609981     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-013-0474-2     Document Type: Article

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