Frequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A, *3B and *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositus

British Journal of Clinical Pharmacology

Volumn 51, Issue 5, 2001, Pages 475-477

  Kubota, T ^a,b,c   Chiba, Kan ^b  

^a SRL INC   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO HOSPITAL   (Japan)

Author keywords

Genotype; Japanese; TPMT*3C

Indexed keywords

MERCAPTOPURINE; MUTANT PROTEIN; THIOPURINE METHYLTRANSFERASE;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HETEROZYGOTE DETECTION; HUMAN; INHERITANCE; JAPAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; PROTEIN VARIANT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHOOL CHILD;

ADULT; GENE FREQUENCY; GENOTYPE; HUMANS; JAPAN; METHYLTRANSFERASES; MIDDLE AGED; MUTATION;

EID: 0034850189     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2001.01371.x     Document Type: Article

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