Thiopurine S-methyltransferase pharmacogenetics in a large-scale healthy Italian-Caucasian population: Differences in enzyme activity

Pharmacogenomics

Volumn 10, Issue 11, 2009, Pages 1753-1765

  Serpe, Loredana ^a   Calvo, Pier Luigi ^b   Muntoni, Elisabetta ^a   D'Antico, Sergio ^c   Giaccone, Mario ^b   Avagnina, Alessandra ^b   Baldi, Maurizio ^b   Barbera, Cristiana ^b   Curti, Franco ^c   Pera, Angelo ^d   Eandi, Mario ^a   Zara, Gian Paolo ^a   Canaparo, Roberto ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b REGINA MARGHERITA CHILDREN S HOSPITAL   (Italy)

^c MOLINETTE HOSPITAL   (Italy)

^d Fondazione IBD Onlus   (Italy)

Author keywords

Age; Gender; Genotype; Phenotype; TPMT

Indexed keywords

THIOPURINE METHYLTRANSFERASE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; BLOOD SAMPLING; CAUCASIAN; CHILD; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; GENE FREQUENCY; GENETIC CORRELATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN EXPERIMENT; INFANT; ITALY; MALE; NEWBORN; NORMAL HUMAN; PHARMACOGENETICS; PHENOTYPE; POPULATION GENETICS; PRESCHOOL CHILD; SCHOOL CHILD; SEX DIFFERENCE; WILD TYPE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CHILD; CHILD, PRESCHOOL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; ITALY; MALE; METHYLTRANSFERASES; MIDDLE AGED; PHARMACOGENETICS; PHENOTYPE; SEX CHARACTERISTICS;

EID: 70649108811     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.09.103     Document Type: Article

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