Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 12, 1997, Pages 6444-6449

  Tai, Hung Liang ^a   Krynetski, Eugene Y ^a   Schuetz, Erin G ^a   Yanishevski, Yuri ^a   Evans, William E ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THIOPURINE METHYLTRANSFERASE;

ALLELE; ARTICLE; CELL LYSATE; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC POLYMORPHISM; HUMAN; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; RISK ASSESSMENT; YEAST;

ALLELES; ANIMALS; CLONING, MOLECULAR; COS CELLS; ENDOPEPTIDASES; ERYTHROCYTES; HUMANS; KINETICS; METHYLTRANSFERASES; POLYMORPHISM, GENETIC; PROTEIN BIOSYNTHESIS; RABBITS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TRANSFECTION;

ORYCTOLAGUS CUNICULUS; STAPHYLOCOCCUS PHAGE 3A;

EID: 0030986251     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.12.6444     Document Type: Article

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