Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population

European Journal of Clinical Pharmacology

Volumn 66, Issue 10, 2010, Pages 999-1003

  Hakooz, Nancy ^c   Arafat, Tawfiq ^a   Payne, Debbie ^b   Ollier, William ^b   Pushpakom, Sudeep ^b   Andrews, Julie ^b   Newman, William ^b  

^a Jordan Center for Pharmaceutical Research Amman   (Jordan)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c NONE

Author keywords

Genotyping; Jordanian population; TPMT

Indexed keywords

THIOPURINE METHYLTRANSFERASE;

ADULT; ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; ENZYME ACTIVITY; EUROPE; GENE FREQUENCY; GENE IDENTIFICATION; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; JORDAN; MALE; NORMAL HUMAN; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ARABS; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; HUMANS; JORDAN; MALE; METHYLTRANSFERASES; POLYMORPHISM, SINGLE NUCLEOTIDE; REFERENCE VALUES;

EID: 77957652268     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0826-1     Document Type: Article

References (32)

1. S Sahasranaman D Howard S Roy 2008 Clinical pharmacology and pharmacogenetics of thiopurines Eur J Clin Pharmacol 64 753 767 1:CAS:528:DC%2BD1cXnsVSls74%3D 10.1007/s00228-008-0478-6 18506437
2. S Zhou 2006 Clinical pharmacogenomics of thiopurine S-methyltransferase Curr Clin Pharmacol 1 119 128 1:CAS:528:DC%2BD28XitFOnsro%3D 18666383
3. K Rutherford V Daggett 2008 Four human thiopurine smethyltransferase alleles severely affect protein structure and dynamics J Mol Biol 379 803 814 1:CAS:528:DC%2BD1cXmsFKqsL8%3D 10.1016/j.jmb.2008.04.032 18482735
4. EA Fargher K Tricker W Newman R Elliott SR Roberts HL Shaffer I Bruce K Payne 2007 Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription J Clin Pharm Ther 32 187 195 1:CAS:528:DC%2BD2sXltFKlur0%3D 10.1111/j.1365-2710.2007. 00805.x 17381669
5. HL McLeod JS Lin EP Scott CH Pui WE Evans 1194 Thiopurine methyltransferase activity in American white subjects and black subjects Clin Pharmacol Ther 55 15 20 10.1038/clpt.1994.4
6. SK Kham CK Soh DC Aw AE Yeoh 2009 TPMT*26 (208F->L), a novel mutation detected in a Chinese Br J Clin Pharmacol 68 1 120 123 1:CAS:528:DC%2BD1MXhtVGjtr3N 10.1111/j.1365-2125.2009.03405.x 19660010
7. CR Yates EY Krynetski T Loennechen 1997 Molecular diagnosis of thiopurine S-methyl transferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance Ann Intern Med 126 608 616 1:CAS:528: DyaK2sXivFehur8%3D 9103127
8. E Schaeffeler C Fischer D Brockmeier D Wernet K Moerike M Eichelbaum UM Zanger M Schwab 2004 Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants Pharmacogenetics 14 407 417 1:CAS:528:DC%2BD2cXlt1Cktrs%3D 10.1097/01.fpc.0000114745.08559.db 15226673
9. HL Tai EY Krynetski CR Yates T Loennechen MY Fessing NF Krynetskaia WE Evans 1996 Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians Am J Hum Genet 58 694 702 1:CAS:528:DyaK28Xitlart7Y%3D 8644731
10. YY Hon MY Fessing CH Pui MV Relling EY Krynetski WE Evans 1999 Polymorphism of the thiopurine S-methyltransferase gene in African-Americans Human Mol Gen 8 371 376 1:CAS:528:DyaK1MXht12ktro%3D 10.1093/hmg/8.2.371
11. LE Larovere RD de Kremer LH Lambooy RA De Abreu 2003 Genetic polymorphism of thiopurine S-methyltransferase in Argentina Ann Clin Biochem 40 388 393 1:CAS:528:DC%2BD3sXmsVSmsb0%3D 10.1258/000456303766477039 12880540
12. WL Boson MA Romano-Silva H Correa RP Falcão PV Teixeira-Vidigal L De Marco 2003 Thiopurine methyltransferase polymorphisms in a Brazilian population Pharmacogenomics J 3 178 182 1:CAS:528:DC%2BD3sXks1Cnu7s%3D 10.1038/sj.tpj.6500175 12815366
13. MM Ameyaw ES Collie-Duguid RH Powrie D Ofori-Adjei HL McLeod 1999 Thiopurine methyltransferase alleles in British and Ghanaian populations Human Mol Gen 8 367 370 1:CAS:528:DyaK1MXht12ksbo%3D 10.1093/hmg/8.2.367
14. JP Zhang YY Guan AL Xu SF Zhou JH Wu H Wei M Huang 2004 Gene mutation of thiopurine S-methyltransferase in Uygur Chinese Eur J Clin Pharm 60 1 3 10.1007/s00228-004-0730-7
15. C Isaza J Henao AM Lopez R Cacabelos 2003 Allelic variants of the thiopurine methyltransferase (TPMT) gene in the Colombian population Meth Find Exp Clin Pharmacol 25 423 429 1:CAS:528:DC%2BD3sXos1Wru70%3D 10.1358/mf.2003.25.6.769646
16. E Efrati L Adler N Krivoy E Sprecher 2009 Distribution of TPMT risk alleles for thioupurine toxicity in the Israeli population Eur J Clin Pharmacol 65 257 262 1:CAS:528:DC%2BD1MXitVyiu7o%3D 10.1007/s00228-008-0590-7 19048244
17. SI Hamdy M Hiratsuka K Narahara N Endo M El-Enany N Moursi MS Ahmed M Mizugaki 2003 Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population Br J Clin Pharm 55 560 569 1:CAS:528: DC%2BD3sXlvFait7k%3D 10.1046/j.1365-2125.2003.01786.x
18. C Ganiere-Monteil Y Medard C Lejus B Bruneau A Pineau O Fenneteau M Bourin E Jacqz-Aigrain 2004 Phenotype and genotype for thiopurine methyltransferase activity in the French Caucasian population: impact of age Eur J Clin Pharmacol 60 89 96 1:CAS:528:DC%2BD2cXjtFyit7s%3D 10.1007/s00228-004- 0732-5 15022030
19. AM Rossi M Bianchi C Guarnieri R Barale GM Pacifici 2001 Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects Eur J Clin Pharm 57 51 54 1:CAS:528:DC%2BD3MXivVylsro%3D 10.1007/s002280000246
20. M Hiratsuka T Inoue F Omori Y Agatsuma M Mizugaki 2000 Genetic analysis of thiopurine methyltransferase in a Japanese population Mutat Res 448 91 95 1:CAS:528:DC%2BD3cXit1aqsr8%3D 10751626
21. H Wei S Zhou C Li J Zhang J Wu M Huang 2005 Phenotyping and genotyping studies of thiopurine S-methyltransferase in Kazaks Pharm Res 22 1762 1766 1:CAS:528:DC%2BD2MXhtVent7nL 10.1007/s11095-005-7095-1 16180135
22. S Alves J Rocha A Amorim MJ Prata 2004 Tracing the origin of the most common thiopurine methyltransferase (TPMT) variants: preliminary data from the patterns of haplotypic association with two CA repeats Ann Hum Genet 68 313 323 1:CAS:528:DC%2BD2cXmvVWqsLs%3D 10.1046/j.1529-8817.2004.00104.x 15225157
23. M Kurzawski B Gawronska-Szklarz M Drozdzik 2004 Frequency distribution of thiopurine S-methyltransferase alleles in a Polish population Ther Drug Monit 26 541 545 1:CAS:528:DC%2BD2cXnslelsbs%3D 10.1097/00007691-200410000-00013 15385838
24. EV Samochatova NV Chupova A Rudneva O Makarova TN Nasedkina OE Fedorova, et al. 2008 TPMT genetic variations in populations of the Russian Federation Pediatr Blood Cancer 52 203 208 10.1002/pbc.21837
25. M Milek J Murn Z Jaksic J Lukac Bajalo J Jazbec I Mlinaric Rascan 2006 Thiopurine S-methyltransferase pharmacogenetics: genotype to phenotype correlation in the Slovenian population Pharmacology 77 105 114 1:CAS:528:DC%2BD28XntFyksb4%3D 10.1159/000093278 16691038
26. S Haglund M Lindqvist S Almer C Peterson J Taipalensuu 2004 Pyrosequencing of TPMT alleles in a general Swedish population and in patients with inflammatory bowel disease Clin Chem 50 288 295 1:CAS:528: DC%2BD2cXhtFKkt7Y%3D 10.1373/clinchem.2003.023846 14656901
27. JG Chang LS Lee CM Chen MC Shih MC Wu FJ Tsai DC Liang 2002 Molecular analysis of thiopurine S-methyltransferase alleles in South-east Asian populations Pharmacogenetics 12 191 195 1:CAS:528:DC%2BD38XnsFKqsLw%3D 10.1097/00008571-200204000-00003 11927834
28. TB Tumer G Ulusoy O Adali G Sahin S Gozdasoglu E Arinc 2007 The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia Am J Hematol 82 906 910 1:CAS:528:DC%2BD2sXht1ahtbrP 10.1002/ajh.20947 17617792
29. ES Collie-Duguid SC Pritchard RH Powrie J Sludden DA Collier T Li HL McLeod 1999 The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations Pharmacogenetics 9 37 42 1:CAS:528:DyaK1MXjtlyqsLw%3D 10.1097/00008571-199902000-00006 10208641
30. P Sánchez-Velasco NS Karadsheh A García-Martín CR de Alegría F Leyva-Cobián 2001 Molecular analysis of HLA allelic frequencies and haplotypes in Jordanians and comparison with other related populations Hum Immunol 62 901 909 10.1016/S0198-8859(01)00289-0 11543892
31. E Oliveira S Quental S Alves A Amorim MJ Prata 2007 Do the distribution patterns of polymorphisms at the thiopurine S-methyltransferase locus in sub-Saharan populations need revision? Hints from Cabinda and Mozambique Eur J Clin Pharmacol 63 703 706 1:CAS:528:DC%2BD2sXmtlGktrY%3D 10.1007/s00228-007- 0310-8 17473918
32. B Banerjee N Saha ZF Daoud FH Khalaf H Qudah 1981 A genetic study of the Jordanians Hum Hered 31 65 69 1:STN:280:DyaL3M7ptVClsg%3D%3D 10.1159/000153179 6939658