Trinucleotide repeat variants in the promoter of the thiopurine S-methyltransferase gene of patients exhibiting ultra-high enzyme activity

Pharmacogenetics and Genomics

Volumn 18, Issue 5, 2008, Pages 434-438

  Roberts, Rebecca L ^a   Gearry, Richard B ^a,b   Bland, Michael V ^a   Sies, Christiaan W ^c   George, Peter M ^c   Burt, Michael ^b   Marinaki, Anthony M ^d   Arenas, Monica ^d   Barclay, Murray L ^a,b   Kennedy, Martin A ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b CHRISTCHURCH HOSPITAL   (New Zealand)

^c CANTERBURY HEALTH LABORATORIES   (New Zealand)

^d GUY S HOSPITAL   (United Kingdom)

Author keywords

Pharmacogenetics; Red blood cell thiopurine S methyl transferase activity; Thiopurine; Thiopurine S methyl transferase mutation

Indexed keywords

LUCIFERASE; THIOPURINE METHYLTRANSFERASE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENTERITIS; ENZYME ACTIVITY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRINUCLEOTIDE REPEAT;

ANIMALS; BASE SEQUENCE; CASE-CONTROL STUDIES; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; GENETIC SCREENING; HUMANS; MALE; METHYLTRANSFERASES; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION; TRINUCLEOTIDE REPEATS;

EID: 42149148677     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3282f85e47     Document Type: Article

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