-
1
-
-
25444442089
-
Comparison of the accuracy of methods of computational haplotype inference using a large empirical dataset
-
Adkins RM (2004) Comparison of the accuracy of methods of computational haplotype inference using a large empirical dataset. BMC Genet 5:22.
-
(2004)
BMC Genet.
, vol.5
, pp. 22
-
-
Adkins, R.M.1
-
3
-
-
48949100515
-
Unraveling ambiguous NAT2 genotyping data
-
Agúndez JA, Golka K, Martínez C, et al. (2008) Unraveling ambiguous NAT2 genotyping data. Clin Chem 54:1390-1394.
-
(2008)
Clin. Chem.
, vol.54
, pp. 1390-1394
-
-
Agúndez, J.A.1
Golka, K.2
Martínez, C.3
-
4
-
-
0029163589
-
Arylamine N-acetyltransferase NAT2 mutations and their allelic linkage in unrelated Caucasian individuals: Correlation with phenotypic activity
-
Cascorbi I, Drakoulis N, Brockmöller J, et al. (1995) Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity. Am J Hum Genet 57:581-592.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 581-592
-
-
Cascorbi, I.1
Drakoulis, N.2
Brockmöller, J.3
-
5
-
-
70349103356
-
Methotrexateinduced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase
-
Celtikci B, Lawrance AK, Wu Q, et al. (2009) Methotrexateinced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase. Anticancer Drugs 20:787-793.
-
(2009)
Anticancer Drugs.
, vol.20
, pp. 787-793
-
-
Celtikci, B.1
Lawrance, A.K.2
Wu, Q.3
-
6
-
-
18344389032
-
Genetic admixture in three Mexican Mestizo populations based on D1S80 and HLA-DQA1 loci
-
DOI 10.1002/ajhb.10020
-
Cerda-Flores RM, Villalobos-Torres MC, Barrera-Saldaña HA, et al. (2002) Genetic admixture in three Mexican Mestizo populations based on D1S80 and HLA-DQA1 loci. Am J Hum Biol 14:257-263. (Pubitemid 34232679)
-
(2002)
American Journal of Human Biology
, vol.14
, Issue.2
, pp. 257-263
-
-
Cerda-Flores, R.M.1
Villalobos-Torres, M.C.2
Barrera-Saldana, H.A.3
Cortes-Prieto, L.M.4
Barajas, L.O.5
Rivas, F.6
Carracedo, A.7
Zhong, Y.8
Barton, S.A.9
Chakraborty, R.10
-
7
-
-
77949478928
-
Pharmacogenetics of phase I and phase II drug metabolism
-
Crettol S, Petrovic N, Murray M (2010) Pharmacogenetics of phase I and phase II drug metabolism. Curr Pharm Des 16:204-219.
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 204-219
-
-
Crettol, S.1
Petrovic, N.2
Murray, M.3
-
8
-
-
14344258388
-
Pharmacogenetics and geographical ancestry: Implications for drug development and global health
-
Daar AS, Singer PA (2005) Pharmacogenetics and geographical ancestry: implications for drug development and global health. Nat Rev Genet 6:241-216.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 241-216
-
-
Daar, A.S.1
Singer, P.A.2
-
9
-
-
65049089761
-
C677T and A1298C MTHFR polymorphisms a challenge for antifolate and fluoropyrimidinebased therapy personalisation
-
De Mattia E, Toffoli G (2009) C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidinebased therapy personalisation. Eur J Cancer 45:1333-1351.
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 1333-1351
-
-
De Mattia, E.1
Toffoli, G.2
-
11
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
Frosst P, Blom HJ, Milos R, et al. (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10:111-113.
-
(1995)
Nat. Genet.
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
-
12
-
-
0033382567
-
Distribution and concordance of N-acetyltransferase genotype and phenotype in an American population
-
Gross M, Kruisselbrink T, Anderson K, et al. (1999) Distribution and concordance of N-acetyltransferase genotype and phenotype in an American population. Cancer Epidemiol Biomarkers Prev 8:683-692. (Pubitemid 30064536)
-
(1999)
Cancer Epidemiology Biomarkers and Prevention
, vol.8
, Issue.8
, pp. 683-692
-
-
Gross, M.1
Kruisselbrink, T.2
Anderson, K.3
Lang, N.4
McGovern, P.5
Delongchamp, R.6
Kadlubar, F.7
-
13
-
-
40549083731
-
Changes in consensus arylamine N-acetyltransferase gene nomenclature
-
DOI 10.1097/FPC.0b013e3282f60db0, PII 0121301120080400000010
-
Hein DW, Boukouvala S, Grant DM, et al. (2008) Changes in consensus arylamine N-acetyltransferase gene nomenclature. Pharmacogen Genomics 18:367-368. (Pubitemid 351367530)
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, Issue.4
, pp. 367-368
-
-
Hein, D.W.1
Boukouvala, S.2
Grant, D.M.3
Minchin, R.F.4
Sim, E.5
-
14
-
-
0036155404
-
Analysis of six SNPs of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype using caffeine
-
DOI 10.1097/00008571-200201000-00006
-
Jorge-Nebert LF, Eichelbaum M, Griese EU, et al. (2002) Analysis of six SNP of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype using caffeine. Pharmacogenetics 12:39-48. (Pubitemid 34112241)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.1
, pp. 39-48
-
-
Jorge-Nebert, L.F.1
Eichelbaum, M.2
Griese, E.-U.3
Inaba, T.4
Arias, T.D.5
-
15
-
-
77954804330
-
Analysis of polymorphisms in genes AGT MTHFR GPIIIa and GSTP1 associated with hypertension, thrombophilia and oxidative stress in Mestizo and Amerindian populations of México
-
Juárez-Velázquez R, Canto P, Canto-Cetina T, et al. (2010) Analysis of polymorphisms in genes (AGT, MTHFR, GPIIIa, and GSTP1) associated with hypertension, thrombophilia and oxidative stress in Mestizo and Amerindian populations of México. Dis Markers 28:323-331.
-
(2010)
Dis. Markers
, vol.28
, pp. 323-331
-
-
Juárez-Velázquez, R.1
Canto, P.2
Canto-Cetina, T.3
-
16
-
-
70649093029
-
Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis
-
Kim SH, Kim SH, Bahn JW, et al. (2009) Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis. Pharmacogenomics 10:1767-1779.
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1767-1779
-
-
Kim, S.H.1
Kim, S.H.2
Bahn, J.W.3
-
17
-
-
28044447631
-
5 10-Methylenetetrahydrofolate reductase polymorphisms and pharmacogenetics: A new role of single nucleotide polymorphisms in the folate metabolic pathway in human health and disease
-
Kim YI (2005) 5,10-Methylenetetrahydrofolate reductase polymorphisms and pharmacogenetics: a new role of single nucleotide polymorphisms in the folate metabolic pathway in human health and disease. Nutr Rev 63:398-407.
-
(2005)
Nutr. Rev.
, vol.63
, pp. 398-407
-
-
Kim, Y.I.1
-
18
-
-
67651229706
-
Role of the MTHFR polymorphisms in cancer risk modification and treatment
-
Kim YI (2009) Role of the MTHFR polymorphisms in cancer risk modification and treatment. Future Oncol 5:523-542.
-
(2009)
Future Oncol.
, vol.5
, pp. 523-542
-
-
Kim, Y.I.1
-
19
-
-
23844516328
-
Pharmacogenetics-based therapeutic recommendations - Ready for clinical practice?
-
DOI 10.1038/nrd1801
-
Kirchheiner J, Fuhr U, Brockmöller J (2005) Pharmacogeneticsbased therapeutic recommendations-ready for clinical practice? Nat Rev Drug Discov 4:639-647. (Pubitemid 41149757)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.8
, pp. 639-647
-
-
Kirchheiner, J.1
Fuhr, U.2
Brockmoller, J.3
-
20
-
-
0036226585
-
Complete sequencing of a genetic polymorphism in NAT2 in the Korean population
-
Lee SY, Lee KA, Ki CS, et al. (2002) Complete sequencing of a genetic polymorphism in NAT2 in the Korean population. Clin Chem 48:775-777.
-
(2002)
Clin. Chem.
, vol.48
, pp. 775-777
-
-
Lee, S.Y.1
Lee, K.A.2
Ki, C.S.3
-
21
-
-
0347361674
-
Modeling Linkage Disequilibrium and Identifying Recombination Hotspots Using Single-Nucleotide Polymorphism Data
-
Li N, Stephens M (2003) Modelling linkage disequilibrium, and identifying recombination hotspots using SNP data. Genetics 165:2213-2233. (Pubitemid 38040302)
-
(2003)
Genetics
, vol.165
, Issue.4
, pp. 2213-2233
-
-
Li, N.1
Stephens, M.2
-
22
-
-
0030903835
-
Genotyping of N-acetylation polymorphism and correlation with procainamide metabolism
-
DOI 10.1016/S0009-9236(97)90131-4
-
Okumura K, Kita T, Chikazawa S, et al. (1997) Genotyping of Nacetylation polymorphism and correlation with procainamide metabolism. Clin Pharmacol Ther 61:509-517. (Pubitemid 27261755)
-
(1997)
Clinical Pharmacology and Therapeutics
, vol.61
, Issue.5
, pp. 509-517
-
-
Okumura, K.1
Kita, T.2
Chikazawa, S.3
Komada, F.4
Iwakawa, S.5
Tanigawara, Y.6
-
23
-
-
70349137184
-
TPMT gene polymorphisms: On the doorstep of personalized medicine
-
Pavlovic S (2009) TPMT gene polymorphisms: on the doorstep of personalized medicine. Indian J Med Res 129:478-480.
-
(2009)
Indian J. Med. Res.
, vol.129
, pp. 478-480
-
-
Pavlovic, S.1
-
24
-
-
0036043220
-
The genetic basis of variability in drug responses
-
Roden DM, George AL Jr. (2002) The genetic basis of variability in drug responses. Nat Rev Drug Discov 1:37-44. (Pubitemid 37361402)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.1
, pp. 37-44
-
-
Roden, D.M.1
George Jr., A.L.2
-
26
-
-
42449142373
-
Pharmacogenomics of anti-TB drugs-related hepatotoxicity
-
DOI 10.2217/14622416.9.3.311
-
Roy PD, Majumder M, Roy B (2008) Pharmacogenomics of anti- TB drugs-related hepatotoxicity. Pharmacogenomics 9:311-321. (Pubitemid 351803934)
-
(2008)
Pharmacogenomics
, vol.9
, Issue.3
, pp. 311-321
-
-
Roy, P.D.1
Majumder, M.2
Roy, B.3
-
28
-
-
0034987699
-
Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1, and L1CAM in the Japanese population
-
DOI 10.1007/s100380170065
-
Sekine A, Saito S, Iida A, et al. (2001) Identification of singlenucleotide polymorphisms (SNP) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population. J Hum Genet 46:314-319. (Pubitemid 32524628)
-
(2001)
Journal of Human Genetics
, vol.46
, Issue.6
, pp. 314-319
-
-
Sekine, A.1
Saito, S.2
Iida, A.3
Mitsunobu, Y.4
Higuchi, S.5
Harigae, S.6
Nakamura, Y.7
-
29
-
-
47649088476
-
Arylamine N-acetyltransferases: From structure to function
-
DOI 10.1080/03602530802186603, PII 795101507
-
Sim E, Walters K, Boukouvala S (2008) Arylamine N-acetyltransferases: from structure to function. Drug Metab Rev 40:479-510. (Pubitemid 352019961)
-
(2008)
Drug Metabolism Reviews
, vol.40
, Issue.3
, pp. 479-510
-
-
Sim, E.1
Walters, K.2
Boukouvala, S.3
-
30
-
-
42949155888
-
Thiopurine S-methyltransferase gene TPMT polymorphisms in a Mexican population of healthy individuals and leukemic patients
-
Taja-Chayeb L, Vidal-Millán S, Gutiérrez O, et al. (2008) Thiopurine S-methyltransferase gene (TPMT) polymorphisms in a Mexican population of healthy individuals and leukemic patients. Med Oncol 25:56-62.
-
(2008)
Med. Oncol.
, vol.25
, pp. 56-62
-
-
Taja-Chayeb, L.1
Vidal-Millán, S.2
Gutiérrez, O.3
-
31
-
-
55449126945
-
Pharmacogenetic relevance of MTHFR polymorphisms
-
Toffoli G, De Mattia E (2008) Pharmacogenetic relevance of MTHFR polymorphisms. Pharmacogenomics 9:1195-1206.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1195-1206
-
-
Toffoli, G.1
De Mattia, E.2
-
32
-
-
0036263469
-
Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
-
DOI 10.1097/00008571-200204000-00002
-
Urano W, Taniguchi A, Yamanaka H, et al. (2002) Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses. Pharmacogenetics 12:183-190. (Pubitemid 34596782)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.3
, pp. 183-190
-
-
Urano, W.1
Taniguchi, A.2
Yamanaka, H.3
Tanaka, E.4
Nakajima, H.5
Matsuda, Y.6
Akama, H.7
Kitamura, Y.8
Kamatani, N.9
-
33
-
-
0031971515
-
A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
-
DOI 10.1086/301825
-
van der Put NM, Gabreëls F, Stevens EM, et al. (1998) A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 62:1044-1051. (Pubitemid 28199004)
-
(1998)
American Journal of Human Genetics
, vol.62
, Issue.5
, pp. 1044-1051
-
-
Van Der Put, N.M.J.1
Gabreels, F.2
Stevens, E.M.B.3
Smeitink, J.A.M.4
Trijbels, F.J.M.5
Eskes, T.K.A.B.6
Van Den Heuvel, L.P.7
Blom, H.J.8
-
34
-
-
75749116389
-
Genetic polymorphism in N-acetyltransferase NAT: Population distribution of NAT1 and NAT2 activity
-
Walker K, Ginsberg G, Hattis D, et al. (2009) Genetic polymorphism in N-acetyltransferase (NAT): population distribution of NAT1 and NAT2 activity. J Toxicol Environ Health B Crit Rev 12:440-472.
-
(2009)
J. Toxicol. Environ. Health B Crit. Rev.
, vol.12
, pp. 440-472
-
-
Walker, K.1
Ginsberg, G.2
Hattis, D.3
-
35
-
-
33645119580
-
Thiopurine S-methyltransferase pharmacogenetics: Insights challenges and future directions
-
Wang L, Weinshilboum R (2006) Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions. Oncogene 25:1629-1638.
-
(2006)
Oncogene
, vol.25
, pp. 1629-1638
-
-
Wang, L.1
Weinshilboum, R.2
-
36
-
-
0033451187
-
Populations and genetic polymorphisms
-
DOI 10.1016/S1084-8592(99)80006-X
-
Weber WW(1999) Populations and genetic polymorphisms. Mol Diagn 4:299-307. (Pubitemid 30036369)
-
(1999)
Molecular Diagnosis
, vol.4
, Issue.4
, pp. 299-307
-
-
Weber, W.W.1
-
37
-
-
4544253691
-
Pharmacogenomics: Bench to bedside
-
DOI 10.1038/nrd1497
-
Weinshilboum R, Wang L (2004) Pharmacogenomics: bench to bedside. Nat Rev Drug Discov 3:739-748. (Pubitemid 39242826)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.9
, pp. 739-748
-
-
Weinshilboum, R.1
Wang, L.2
-
38
-
-
0030934850
-
Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
-
Yates CR, Krynetski EY, Loennechen T, et al. (1997) Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 126:608-614. (Pubitemid 27172187)
-
(1997)
Annals of Internal Medicine
, vol.126
, Issue.8
, pp. 608-614
-
-
Yates, C.R.1
Krynetski, E.Y.2
Loennechen, T.3
Fessing, M.Y.4
Tai, H.-L.5
Pui, C.-H.6
Relling, M.V.7
Evans, W.E.8
-
39
-
-
34250304874
-
Clinical pharmacogenomics of thiopurine S-methyltransferase
-
Zhou S (2006) Clinical pharmacogenomics of thiopurine S-methyltransferase. Curr Clin Pharmacol 1:119-128.
-
(2006)
Curr. Clin. Pharmacol.
, vol.1
, pp. 119-128
-
-
Zhou, S.1
-
40
-
-
70149110672
-
Polymorphism of human cytochrome P450 enzymes and its clinical impact
-
Zhou SF, Liu JP, Chowbay B (2009) Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev 41:89-295.
-
(2009)
Drug. Metab. Rev.
, vol.41
, pp. 89-295
-
-
Zhou, S.F.1
Liu, J.P.2
Chowbay, B.3
|