HAMI 3379, a CysLT2 receptor antagonist, attenuates ischemia-like neuronal injury by inhibiting microglial activation

Journal of Pharmacology and Experimental Therapeutics

Volumn 346, Issue 2, 2013, Pages 328-341

  Zhang, Xia Yan ^a   Wang, Xiao Rong ^a   Xu, Dong Min ^a   Yu, Shu Ying ^a   Shi, Qiao Juan ^a   Zhang, Li Hui ^b   Chen, Lu ^b   Fang, San Hua ^a   Lu, Yun Bi ^a   Zhang, Wei Ping ^a   Wei, Er Qing ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 [[(3 CARBOXYCYCLOHEXYL)AMINO]CARBONUYL] 4 [3 [4 [4 (CYCLOHEXYLOXY)BUTOXY]PHENYL]PROPOXY]BENZOIC ACID; CYSTEINYL LEUKOTRIENE RECEPTOR 1; CYSTEINYL LEUKOTRIENE RECEPTOR 2; HAMI 3379; INTERLEUKIN 1BETA; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-(((3-CARBOXYCYCLOHEXYL)AMINO)CARBONYL)-4-(3-(4-(4-(CYCLOHEXYLOXY)BUTOXY)PHENYL)PROPOXY)BENZOIC ACID; ACETIC ACID DERIVATIVE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; CYTOKINE; GLUCOSE; OXYGEN; PHTHALIC ACID DERIVATIVE; QUINOLINE DERIVATIVE; 3 (((3 CARBOXYCYCLOHEXYL)AMINO)CARBONYL) 4 (3 (4 (4 (CYCLOHEXYLOXY)BUTOXY)PHENYL)PROPOXY)BENZOIC ACID;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL LOSS; COCULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; MICROGLIA; NERVE CELL CULTURE; NERVE CELL LESION; NEWBORN; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; AGONISTS; ANIMAL; ASTROCYTE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; DRUG EFFECTS; FEMALE; MALE; METABOLISM; NECROSIS; NERVE CELL; PATHOLOGY; PRIMARY CELL CULTURE; SPRAGUE DAWLEY RAT; DRUG EFFECT; DRUG POTENTIATION;

ACETATES; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BRAIN ISCHEMIA; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; CYCLOHEXANECARBOXYLIC ACIDS; CYTOKINES; FEMALE; GLUCOSE; LEUKOTRIENE ANTAGONISTS; MALE; MICROGLIA; NECROSIS; NEURONS; OXYGEN; PHAGOCYTOSIS; PHTHALIC ACIDS; PRIMARY CELL CULTURE; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LEUKOTRIENE;

EID: 84880407494     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.203604     Document Type: Article

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