The new P2Y-like receptor G protein-coupled receptor 17 mediates acute neuronal injury and late microgliosis after focal cerebral ischemia in rats

Neuroscience

Volumn 202, Issue , 2012, Pages 42-57

  Zhao, B ^a   Zhao, C Z ^a   Zhang, X Y ^a   Huang, X Q ^a   Shi, W Z ^a   Fang, S H ^a   Lu, Y B ^a   Zhang, W P ^a   Xia, Q ^a   Wei, E Q ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cerebral ischemia; GPR17; Microgliosis; Neuronal injury; RNA interference

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 17; MESSENGER RNA; PURINERGIC P2Y RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL ACTIVATION; CELLULAR DISTRIBUTION; CHRONIC DISEASE; CONTROLLED STUDY; DEPTH PERCEPTION; DISEASE SEVERITY; G PROTEIN COUPLED RECEPTOR 17 GENE; GENE EXPRESSION REGULATION; GENE SILENCING; GLIOSIS; MALE; MICROGLIA; NERVOUS SYSTEM INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RECEPTOR GENE; TIME PERCEPTION; UPREGULATION;

ANIMALS; BEHAVIOR, ANIMAL; BLOOD GLUCOSE; BLOOD PRESSURE; BLOTTING, WESTERN; BRAIN ISCHEMIA; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; INFARCTION, MIDDLE CEREBRAL ARTERY; INJECTIONS, INTRAVENTRICULAR; ISCHEMIC ATTACK, TRANSIENT; MALE; MICROGLIA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PURINERGIC P2Y; RNA, SMALL INTERFERING;

EID: 84856235011     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.11.066     Document Type: Article

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