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Volumn 20, Issue 22, 2013, Pages 2779-2797

Platelets and atherothrombosis: Causes, targets and treatments for thrombosis

Author keywords

ADP; Atherothrombosis; Collagen; Fibrinogen; Platelet receptor antagonists; Platelets; Thrombin; Thromboxane

Indexed keywords

3 [[4 [4 [AMINO(ETHOXYCARBONYLIMINO)METHYL]PHENYL] 2 THIAZOLYL](1 ETHOXYCARBONYLMETHYL 4 PIPERIDINYL)AMINO]PROPIONIC ACID ETHYL ESTER; ABCIXIMAB; ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; ARC 669931MX; CANGRELOR; CLOPIDOGREL; DAZOXIBEN; ELAROFIBAN; ELINOGREL; EPTIFIBATIDE; FRADAFIBAN; GANTOFIBAN; INDOBUFEN; LAMIFIBAN; LEFRADAFIBAN; LOTRAFIBAN; ORBOFIBAN; PRASUGREL; RIDOGREL; ROXIFIBAN; RWJ 3308; SB 214587; SIBRAFIBAN; SULFINPYRAZONE; SULOTROBAN; TERUTROBAN; THROMBOXANE A2; TICAGRELOR; TICLOPIDINE; TIROFIBAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; XEMILOFIBAN;

EID: 84880307477     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867311320220004     Document Type: Article
Times cited : (51)

References (197)
  • 2
    • 49949106788 scopus 로고    scopus 로고
    • Getting to the heart of the matter in India
    • Kohn, D. Getting to the heart of the matter in India. The Lancet, 2008, 372, 523-524
    • (2008) The Lancet , vol.372 , pp. 523-524
    • Kohn, D.1
  • 3
    • 85013973898 scopus 로고    scopus 로고
    • 2nd Edn. Elsevier/Academic Press, San Diego
    • Michelson, A D. Platelets 2nd edn. Elsevier/Academic Press, San Diego, 2007.
    • (2007) Platelets
    • Michelson A, D.1
  • 4
    • 75949128633 scopus 로고    scopus 로고
    • Antiplatelet therapies for the treatment of cardiovascular disease
    • Alan, D. M. Antiplatelet therapies for the treatment of cardiovascular disease. Nature Reviews: Drug Discovery, 2010, 9, 154-169.
    • (2010) Nature Reviews: Drug Discovery , vol.9 , pp. 154-169
    • Alan, D.M.1
  • 5
    • 0023712653 scopus 로고
    • Platelet and atherosclerosis
    • Hoak, J.C. Platelet and atherosclerosis. Thromb Hemost, 1988, 14, 202-205.
    • (1988) Thromb Hemost , vol.14 , pp. 202-205
    • Hoak, J.C.1
  • 6
    • 0027979451 scopus 로고
    • Recent observations on the role of hemostatic determinants in the development of the atherothrombotic plaque
    • Rabbani, L.E.; Loscalzo, J. Recent observations on the role of hemostatic determinants in the development of the atherothrombotic plaque. Atherosclerosis, 1994, 105, 1-7.
    • (1994) Atherosclerosis , vol.105 , pp. 1-7
    • Rabbani, L.E.1    Loscalzo, J.2
  • 7
    • 30144446003 scopus 로고    scopus 로고
    • Platelets in atherothrombosis
    • David, A. V.; Richard, B. Platelets in atherothrombosis. Mayo Clin Proc., 2006, 81(1), 59-68
    • (2006) Mayo Clin Proc. , vol.81 , Issue.1 , pp. 59-68
    • David, A.V.1    Richard, B.2
  • 8
    • 84884795579 scopus 로고    scopus 로고
    • 2nd edn, Elsevier/Academic Press, San Diego
    • Italiano, J. E.; Hartwig, J. H.; Platelets 2nd edn, Elsevier/Academic Press, San Diego, 2007, 23-44.
    • (2007) Platelets , pp. 23-44
    • Italiano, J.E.1    Hartwig, J.H.2
  • 9
    • 0014068204 scopus 로고
    • Blood coagulation and haemostasis: A review
    • Roderique, E. M.; Wynands, J. E.; Blood coagulation and haemostasis: A review. Can. Anaes. Soc. J., 1967, 14(2), 129-151.
    • (1967) Can. Anaes. Soc. J. , vol.14 , Issue.2 , pp. 129-151
    • Roderique, E.M.1    Wynands, J.E.2
  • 11
    • 0345732422 scopus 로고    scopus 로고
    • Diffuse alveolar hemorrhage after allogeneic hematopoietic stem-cell transplantation; Treatment with recombinant factor VIIa
    • Stephen, M. P.; Esperanza, P.; Louis, V.; Neil, A. H. Diffuse alveolar hemorrhage after allogeneic hematopoietic stem-cell transplantation; Treatment with recombinant factor VIIa. Chest, 2003,124, 2400-2403.
    • (2003) Chest , vol.124 , pp. 2400-2403
    • Stephen, M.P.1    Esperanza, P.2    Louis, V.3    Neil, A.H.4
  • 12
    • 34247190302 scopus 로고    scopus 로고
    • Platelet adhesion receptors and their ligands in mouse models of thrombosis
    • Denis, C. V.; Wagner, D. D. Platelet Adhesion Receptors and Their Ligands in Mouse Models of Thrombosis. Arterioscler. Thromb. Vasc. Biol., 2007, 27, 728-739.
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 728-739
    • Denis, C.V.1    Wagner, D.D.2
  • 13
    • 0036851876 scopus 로고    scopus 로고
    • Platelets in atherothrombosis
    • Zaverio, M. R. Platelets in atherothrombosis. Nature Medicine, 2002, 8(11), 1227-1234
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1227-1234
    • Zaverio, M.R.1
  • 16
    • 0037212317 scopus 로고    scopus 로고
    • Vascular collagens: Spotlight on the role of type VIII collagen in atherogenesis
    • Plenz, G.A.; Deng, M.C.; Robenek, H; Volker, W. Vascular collagens: Spotlight on the role of type VIII collagen in atherogenesis. Artherosclerosis, 2003, 166, 1-11.
    • (2003) Artherosclerosis , vol.166 , pp. 1-11
    • Plenz, G.A.1    Deng, M.C.2    Robenek, H.3    Volker, W.4
  • 17
    • 0027489871 scopus 로고
    • Platelet adhesion to cyanogen-bromide fragments of collagen alpha 1 (I) under flow conditions
    • Saelman, E.U.; Horton, L.F.; Barnes, M.J.; Gralnick, H.R.; Hese, K.M. Nieuwenhuis, H.K. Platelet adhesion to cyanogen-bromide fragments of collagen alpha 1(I) under flow conditions. Blood, 1993, 82, 3029-3033.
    • (1993) Blood , vol.82 , pp. 3029-3033
    • Saelman, E.U.1    Horton, L.F.2    Barnes, M.J.3    Gralnick, H.R.4    Hese, K.M.5    Nieuwenhuis, H.K.6
  • 18
    • 0022512575 scopus 로고
    • Collagen types in various layers of the human aorta and their changes with the atherosclerotic process
    • Murata, K.; Motayama, T.; Kotake, C. Collagen types in various layers of the human aorta and their changes with the atherosclerotic process. Atheroclerosis, 1986, 60, 251-262.
    • (1986) Atheroclerosis , vol.60 , pp. 251-262
    • Murata, K.1    Motayama, T.2    Kotake, C.3
  • 19
    • 0022353697 scopus 로고
    • Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia
    • Nieuwenhuis, H.K.; Akkerman, J.W.; Houdijk, W.P.; Sixma, J.J. Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia. Nature. 1985, 318, 470-472.
    • (1985) Nature. , vol.318 , pp. 470-472
    • Nieuwenhuis, H.K.1    Akkerman, J.W.2    Houdijk, W.P.3    Sixma, J.J.4
  • 20
    • 0022922723 scopus 로고
    • Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen
    • Santoro, S.A. Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen. Cell, 1986, 46, 913-920.
    • (1986) Cell , vol.46 , pp. 913-920
    • Santoro, S.A.1
  • 21
    • 0028979497 scopus 로고
    • The alpha 2 beta 1 inte integrin: A collagen receptor on platelets and other cells
    • Santoro, S.A.; Zutter, M.M. The alpha 2 beta 1 inte integrin: A collagen receptor on platelets and other cells. Thromb Haemost. 1995, 74, 813-821
    • (1995) Thromb Haemost. , vol.74 , pp. 813-821
    • Santoro, S.A.1    Zutter, M.M.2
  • 22
    • 0019973882 scopus 로고
    • Characterization of the platelet membrane glycoprotein abnormalities in Bernard-Soulier syndrome and comparison with normal by surface-labeling techniques and high-resolution two-dimensional gel electrophoresis
    • Clemetson, K.J.; McGregor, J.L.; James, E.; Dechavanne, M.; Luscher, E.F. Characterization of the platelet membrane glycoprotein abnormalities in Bernard-Soulier syndrome and comparison with normal by surface-labeling techniques and high-resolution two-dimensional gel electrophoresis. J. Clin. Invest., 1982, 70, 304-311.
    • (1982) J. Clin. Invest. , vol.70 , pp. 304-311
    • Clemetson, K.J.1    McGregor, J.L.2    James, E.3    Dechavanne, M.4    Luscher, E.F.5
  • 23
    • 0034284219 scopus 로고    scopus 로고
    • Cloning characterization and functional studies of human and mouse glycoprotein VI: A platelet-specific collagen receptor from the immunoglobulin superfamily
    • Jandrot-Perrus, M.; Busfield, S.; Lagrue, A.H. Cloning, characterization, and functional studies of human and mouse glycoprotein VI: A platelet-specific collagen receptor from the immunoglobulin superfamily. Blood, 2000, 96, 1798-1807.
    • (2000) Blood , vol.96 , pp. 1798-1807
    • Jandrot-Perrus, M.1    Busfield, S.2    Lagrue, A.H.3
  • 24
    • 0032828086 scopus 로고    scopus 로고
    • The platelet collagen receptor glycoprotein VI Is a member of the immunoglobulin superfamily closely related to FcαR and the natural killer receptors
    • Clemetson, J.M.; Polgar, J.; Magnenat, E.; Wells, T.N.; Clemetson, K.J. The Platelet Collagen Receptor Glycoprotein VI Is a Member of the Immunoglobulin Superfamily Closely Related to FcαR and the Natural Killer Receptors J. Biol. Chem., 1999, 274, 29019-29024.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29019-29024
    • Clemetson, J.M.1    Polgar, J.2    Magnenat, E.3    Wells, T.N.4    Clemetson, K.J.5
  • 25
    • 52049111404 scopus 로고    scopus 로고
    • Platelet collagen receptors, signaling and antagonism: Emerging approaches for the prevention of intravascular thrombosis
    • Surin, W.R.; Barthwal, M.K.; Dikshit, M. Platelet collagen receptors, signaling and antagonism: Emerging approaches for the prevention of intravascular thrombosis. Thromb Res., 2008, 122, 786-803.
    • (2008) Thromb Res. , vol.122 , pp. 786-803
    • Surin, W.R.1    Barthwal, M.K.2    Dikshit, M.3
  • 28
    • 0038494921 scopus 로고    scopus 로고
    • Platelet-collagen interaction: Is GPVI the central receptor?
    • Bernhard, N.; Steve, P. W. Platelet-collagen interaction: Is GPVI the central receptor? Blood, 2003, 102(2), 449-461
    • (2003) Blood , vol.102 , Issue.2 , pp. 449-461
    • Bernhard, N.1    Steve, P.W.2
  • 29
    • 84880301339 scopus 로고    scopus 로고
    • San Diego CA: Academic Press
    • Savage, B.; Ruggeri, Z. M. Platelets. San Diego, CA: Academic Press, 2002: 215-228.
    • (2002) Platelets , pp. 215-228
    • Savage, B.1    Ruggeri, Z.M.2
  • 30
    • 0242453920 scopus 로고    scopus 로고
    • San Diego CA: Academic Press
    • Lopez, J. A.; Berndt, M. C. Platelets. San Diego, CA: Academic Press, 2002: 85-97.
    • (2002) Platelets. , pp. 85-97
    • Lopez, J.A.1    Berndt, M.C.2
  • 31
    • 0038157329 scopus 로고    scopus 로고
    • Crystal structure of the gpibα-thrombin complex essential for platelet aggregation
    • John, J. D.; Kumar, R.; Seehra, J.; Somers, S. S.; Lidia, M. Crystal Structure of the GpIbα-Thrombin Complex Essential for Platelet Aggregation. Science, 2003, 301, 222-226
    • (2003) Science , vol.301 , pp. 222-226
    • John, J.D.1    Kumar, R.2    Seehra, J.3    Somers, S.S.4    Lidia, M.5
  • 32
    • 0030748125 scopus 로고    scopus 로고
    • Mechanisms initiating platelet thrombus formation
    • Ruggeri, Z. M. Mechanisms initiating platelet thrombus formation. Thromb. Haemost., 1997, 78, 611-616.
    • (1997) Thromb. Haemost. , vol.78 , pp. 611-616
    • Ruggeri, Z.M.1
  • 33
    • 13344295095 scopus 로고    scopus 로고
    • Initiation of platelet adhesion by attachment onto fibrinogen or translocation on von Willebrand factor
    • Savage, B.; Saldivar. E.; Ruggeri, Z. M. Initiation of platelet adhesion by attachment onto fibrinogen or translocation on von Willebrand factor. Cell, 1996, 84, 289-297
    • (1996) Cell , vol.84 , pp. 289-297
    • Savage, B.1    Saldivar, E.2    Ruggeri, Z.M.3
  • 34
    • 0024532116 scopus 로고
    • Molecular mechanisms of platelet activation
    • Siess, W. Molecular mechanisms of platelet activation. Physiol Rev., 1989, 69, 158-178.
    • (1989) Physiol Rev. , vol.69 , pp. 158-178
    • Siess, W.1
  • 36
    • 0030470605 scopus 로고    scopus 로고
    • ADP receptors on platelets
    • Mills, D.C.B. ADP receptors on platelets. Thromb Haemost., 1996, 76, 835-856.
    • (1996) Thromb Haemost. , vol.76 , pp. 835-856
    • Mills, D.C.B.1
  • 40
    • 23644443379 scopus 로고    scopus 로고
    • Adenosine diphosphate receptors on blood platelets: Potential new targets for antiplatelet therapy
    • Marcin, R.; Marek, N.; Cezary W. Adenosine diphosphate receptors on blood platelets: Potential new targets for antiplatelet therapy. Acta Biochimica Polonica, 2005, 52(2), 411-415.
    • (2005) Acta Biochimica Polonica , vol.52 , Issue.2 , pp. 411-415
    • Marcin, R.1    Marek, N.2    Cezary, W.3
  • 41
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic, V.; Burnstock, G.; Receptors for Purines and Pyrimidines. Pharmacol. Rev., 1998, 50, 413-492.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 42
    • 0034911702 scopus 로고    scopus 로고
    • ADP receptors of platelets and their inhibition
    • Gachet, C. ADP receptors of platelets and their inhibition.Thromb Haemost., 2001, 86, 222-232.
    • (2001) Thromb Haemost. , vol.86 , pp. 222-232
    • Gachet, C.1
  • 43
    • 0030059479 scopus 로고    scopus 로고
    • Activation of receptor-operated cation channels via purinoceptors in human platelets
    • MacKenzie, A.B.; Mahaut-Smith, M.P.; Sage, S.O. Activation of Receptor-operated Cation Channels via Purinoceptors in Human Platelets. J. Biol. Chem., 1996, 271, 2879-2881.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2879-2881
    • MacKenzie, A.B.1    Mahaut-Smith, M.P.2    Sage, S.O.3
  • 44
    • 0036095953 scopus 로고    scopus 로고
    • Adenosine diphosphate (ADP)-induced thromboxane A2 generation in human platelets requires coordinated signaling through integrin alphaIIbbeta3 and ADP receptors
    • Jin, J.; Quinton, T.M.; Zhang, J.; Rittenhouse, S.E.; Kunapuli, S.P. Adenosine diphosphate (ADP)-induced thromboxane A2 generation in human platelets requires coordinated signaling through integrin alphaIIbbeta3 and ADP receptors. Blood, 2002, 99, 193-198.
    • (2002) Blood , vol.99 , pp. 193-198
    • Jin, J.1    Quinton, T.M.2    Zhang, J.3    Rittenhouse, S.E.4    Kunapuli, S.P.5
  • 45
    • 0031956683 scopus 로고    scopus 로고
    • How Thrombin "talks" to cells: Molecular mechanisms and roles in vivo
    • Coughlin, S. R. How thrombin "talks" to cells: Molecular mechanisms and roles in vivo. Arterioscler. Thromb Vasc. Biol., 1998, 18, 514-518.
    • (1998) Arterioscler. Thromb Vasc. Biol. , vol.18 , pp. 514-518
    • Coughlin, S.R.1
  • 46
    • 0026782001 scopus 로고
    • The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinoside hydrolysis and inhibit adenylyl cyclase
    • Hung, D. T.; Wong, Y. H.; Vu, T. K.; Coughlin, S. R. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinoside hydrolysis and inhibit adenylyl cyclase. J. Biol. Chem., 1992, 267, 20831-20834
    • (1992) J. Biol. Chem. , vol.267 , pp. 20831-20834
    • Hung, D.T.1    Wong, Y.H.2    Vu, T.K.3    Coughlin, S.R.4
  • 47
    • 0034625055 scopus 로고    scopus 로고
    • Activation and inhibition of G protein-coupled receptors by cell-penetrating membranetethered peptides
    • Covic, L.; Gresser, A. L.; Kuliopulos, A. Activation and inhibition of G protein-coupled receptors by cell-penetrating membranetethered peptides. Biochemistry, 2000, 39, 5458-5467.
    • (2000) Biochemistry , vol.39 , pp. 5458-5467
    • Covic, L.1    Gresser, A.L.2    Kuliopulos, A.3
  • 48
    • 0026775223 scopus 로고
    • Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides
    • Vassallo, R. R.; Jr Kieber-Emmons, T.; Cichowski, K.; Brass, L. F. Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J. Biol. Chem., 1992, 267, 6081-6085.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6081-6085
    • Vassallo, R.R.1    Kieber-Emmons Jr., T.2    Cichowski, K.3    Brass, L.F.4
  • 50
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu, T. K.; Hung, D. T.; Wheaton, V. I.; Coughlin, S. R.; Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell, 1991, 64, 1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 51
    • 31044441154 scopus 로고    scopus 로고
    • Structure and function of the platelet integrin αIIbβ;3
    • Bennett, J.S. Structure and function of the platelet integrin αIIbβ;3. J. Clin. Invest., 2005, 115, 3363-3369.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3363-3369
    • Bennett, J.S.1
  • 52
    • 43749099194 scopus 로고    scopus 로고
    • IIb/IIIa antagonists in acute ischaemic stroke: Current sta-tus and future directions
    • Pitchaiah, M.; Perumal, T.; Thomas, A. K. IIb/IIIa antagonists in acute ischaemic stroke: Current sta-tus and future directions. Drugs, 2008, 68(8), 1019-1028.
    • (2008) Drugs , vol.68 , Issue.8 , pp. 1019-1028
    • Pitchaiah, M.1    Perumal, T.2    Thomas, A.K.3
  • 53
    • 0025253068 scopus 로고
    • Glanzmann's thrombasthenia: The spectrum of clinical disease
    • George, J.N.; Caen, J.P.; Nurden, A.T. Glanzmann's thrombasthenia: The spectrum of clinical disease. Blood, 1990, 75, 1383-1395.
    • (1990) Blood , vol.75 , pp. 1383-1395
    • George, J.N.1    Caen, J.P.2    Nurden, A.T.3
  • 54
    • 4444264392 scopus 로고    scopus 로고
    • Integrins: Dynamic scaffolds for adhesion and signaling in platelets
    • Shattil, S.J.; Newman, P.J. Integrins: Dynamic scaffolds for adhesion and signaling in platelets. Blood, 2004, 104, 1606-1615.
    • (2004) Blood , vol.104 , pp. 1606-1615
    • Shattil, S.J.1    Newman, P.J.2
  • 55
    • 0029062761 scopus 로고
    • Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine
    • Lefkovits, J.; Plow, E.F.; Topol, E. Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine. N. Engl. J. Med., 1995, 23, 1553-1559.
    • (1995) N. Engl. J. Med. , vol.23 , pp. 1553-1559
    • Lefkovits, J.1    Plow, E.F.2    Topol, E.3
  • 56
    • 0031459452 scopus 로고    scopus 로고
    • Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics
    • Coller, B.S. Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics. J Clin Invest., 1997, 100, S57-S60.
    • (1997) J Clin Invest. , vol.100
    • Coller, B.S.1
  • 57
    • 0029798675 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa receptor inhibitors: Putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective
    • Tscheng, J.E. Glycoprotein IIb/IIIa receptor inhibitors: Putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective. Am. J. Cardiol., 1996, 78, 35-40.
    • (1996) Am. J. Cardiol. , vol.78 , pp. 35-40
    • Tscheng, J.E.1
  • 58
    • 0030611288 scopus 로고    scopus 로고
    • GPIIb/IIIa antagonists: Pathophysiologic and therapeutic insights from studies of c7E3 Fab
    • Coller, B.S. GPIIb/IIIa antagonists: Pathophysiologic and therapeutic insights from studies of c7E3 Fab. Thromb Haemost., 1997, 78, 730-735.
    • (1997) Thromb Haemost. , vol.78 , pp. 730-735
    • Coller, B.S.1
  • 59
    • 0033573790 scopus 로고    scopus 로고
    • Platelet GPIIb-IIIa blockers
    • Topol, E.J.; Byzova, T.V.; Plow, E.F. Platelet GPIIb-IIIa blockers. Lancet, 1999, 353, 227-231.
    • (1999) Lancet , vol.353 , pp. 227-231
    • Topol, E.J.1    Byzova, T.V.2    Plow, E.F.3
  • 60
    • 0023164662 scopus 로고
    • Thromboxane A2 biosynthesis in human disease
    • FitzGerald, G.A.; Healy, C.D. Thromboxane A2 biosynthesis in human disease. J. Fed Proc., 1987, 46, 154-158.
    • (1987) J. Fed Proc. , vol.46 , pp. 154-158
    • FitzGerald, G.A.1    Healy, C.D.2
  • 61
    • 0034746834 scopus 로고    scopus 로고
    • Necessity of thromboxane A2 for initiation of platelet-mediated contact sensitivity: Dual activation of platelets and vascular endothelial cells
    • Motoki, M.; Tanaka, A.; Fujisawa, C.; Kawamoto, K.; Itakura, A.; Takaku, M.; Hironaka, T.; Sawada, S.; Matsuda, H. Necessity of Thromboxane A2 for Initiation of Platelet-Mediated Contact Sensitivity: Dual Activation of Platelets and Vascular Endothelial Cells. J. Immunol., 2001, 166, 617-623.
    • (2001) J. Immunol. , vol.166 , pp. 617-623
    • Motoki, M.1    Tanaka, A.2    Fujisawa, C.3    Kawamoto, K.4    Itakura, A.5    Takaku, M.6    Hironaka, T.7    Sawada, S.8    Matsuda, H.9
  • 62
    • 0025952271 scopus 로고
    • Pharmacological receptors on blood platelets
    • Hourani, S. M.; Cusack, N. J. Pharmacological receptors on blood platelets. Pharmacol. Rev., 1991, 43, 243-298
    • (1991) Pharmacol. Rev. , vol.43 , pp. 243-298
    • Hourani, S.M.1    Cusack, N.J.2
  • 63
    • 0031809716 scopus 로고    scopus 로고
    • Thromboxanes: Synthase and receptors
    • Shen, R. F.; Tai, H.H. Thromboxanes: Synthase and receptors J. Biomed. Sci., 1998, 5, 153-172.
    • (1998) J. Biomed. Sci. , vol.5 , pp. 153-172
    • Shen, R.F.1    Tai, H.H.2
  • 64
    • 0026052859 scopus 로고
    • Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists
    • FitzGerald, G. A. Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists. Am. J. Cardiol., 1991, 68, 11B-15B.
    • (1991) Am. J. Cardiol. , vol.68
    • FitzGerald, G.A.1
  • 65
    • 0032828089 scopus 로고    scopus 로고
    • Molecular mechanism of thromboxane A2-induced platelet aggregation essential role for P2TAC and α2A receptors
    • Benjamin, Z. S.; Paul, J. J.; Satya, P. K. Molecular mechanism of thromboxane A2-induced platelet aggregation essential role for P2TAC and α2A receptors. J. Biol. Chem., 1999, 274(41), 29108-29114.
    • (1999) J. Biol. Chem. , vol.274 , Issue.41 , pp. 29108-29114
    • Benjamin, Z.S.1    Paul, J.J.2    Satya, P.K.3
  • 68
    • 33847060979 scopus 로고    scopus 로고
    • The role of von Willebrand Factor in hemorrhagic and thrombotic disorders
    • Massimo, F.; Giuseppe, L. The role of von Willebrand Factor in hemorrhagic and thrombotic disorders. Crit. Rev. Clin. Lab. Sci., 2007, 44(2), 115-149.
    • (2007) Crit. Rev. Clin. Lab. Sci. , vol.44 , Issue.2 , pp. 115-149
    • Massimo, F.1    Giuseppe, L.2
  • 70
    • 0034066977 scopus 로고    scopus 로고
    • Old concepts and new developments in the study of platelet aggregation
    • Ruggeri, Z.M. Old concepts and new developments in the study of platelet aggregation. J. Clin. Invest., 2000, 105, 699-701.
    • (2000) J. Clin. Invest. , vol.105 , pp. 699-701
    • Ruggeri, Z.M.1
  • 72
    • 0021921386 scopus 로고
    • Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation
    • De Marco, L.; Girolami, A.; Russell, S, Ruggeri, Z. M. Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation J. Clin. Invest., 1985, 75, 1198-1203.
    • (1985) J. Clin. Invest. , vol.75 , pp. 1198-1203
    • De Marco, L.1    Girolami, A.2    Russell, S.3    Ruggeri, Z.M.4
  • 73
    • 13344295095 scopus 로고    scopus 로고
    • Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor
    • Savage, B.; Saldivar, E.; Ruggeri, Z.M. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell, 1996, 84, 289-297.
    • (1996) Cell , vol.84 , pp. 289-297
    • Savage, B.1    Saldivar, E.2    Ruggeri, Z.M.3
  • 74
    • 0036851876 scopus 로고    scopus 로고
    • Platelets in atherothrombosis
    • Zaverio, M.; Ruggeri, Z.M. Platelets in atherothrombosis Nat. Med., 2002, 8(11), 1227-1234.
    • (2002) Nat. Med. , vol.8 , Issue.11 , pp. 1227-1234
    • Zaverio, M.1    Ruggeri, Z.M.2
  • 76
    • 73349110089 scopus 로고    scopus 로고
    • Inhibitors of platelet adhesion
    • Todd, L. K.; Richard, C. B. Inhibitors of Platelet Adhesion, Circulation, 2009, 120, 2488-2495.
    • (2009) Circulation , vol.120 , pp. 2488-2495
    • Todd, L.K.1    Richard, C.B.2
  • 77
    • 0037296525 scopus 로고    scopus 로고
    • Role of activation-dependent platelet membrane glycoproteins in development of subacute occlusive coronary stent thrombosis
    • Samara, W.M.; Gurbel, P.A. Role of activation-dependent platelet membrane glycoproteins in development of subacute occlusive coronary stent thrombosis. Coron. Artery Dis., 2003, 14, 65-79.
    • (2003) Coron. Artery Dis. , vol.14 , pp. 65-79
    • Samara, W.M.1    Gurbel, P.A.2
  • 80
    • 30144446003 scopus 로고    scopus 로고
    • Platelets in atherothrombosis
    • David, A. V.; Richard, B. Platelets in atherothrombosis. Mayo Clin. Proc., 2006, 81(1), 59-68.
    • (2006) Mayo Clin. Proc. , vol.81 , Issue.1 , pp. 59-68
    • David, A.V.1    Richard, B.2
  • 81
    • 28344439657 scopus 로고    scopus 로고
    • Platelets in atherothrombosis: Lessons from mouse models
    • Nieswandt, B.; Aktas, B.; Moers, A.; Sachs, U. J. H. Platelets in atherothrombosis: Lessons from mouse models. J. Thromb Haemost., 2005, 3, 1725-1736.
    • (2005) J. Thromb Haemost. , vol.3 , pp. 1725-1736
    • Nieswandt, B.1    Aktas, B.2    Moers, A.3    Sachs, U.J.H.4
  • 84
    • 85013973898 scopus 로고    scopus 로고
    • 2nd Ed. Elsevier, Academic Press, San Diego
    • Cattaneo, M. Platelets 2nd ed. Elsevier, Academic Press, San Diego, 2007, 201-220.
    • (2007) Platelets , pp. 201-220
    • Cattaneo, M.1
  • 85
    • 0042703242 scopus 로고    scopus 로고
    • Scientific and therapeutic insights into the role of the platelet P2Y1 2 receptor in thrombosis
    • Conley, P.B.; Delaney, S.M. Scientific and therapeutic insights into the role of the platelet P2Y1 2 receptor in thrombosis Curr. Opin. Hematol., 2003, 10, 333-338.
    • (2003) Curr. Opin. Hematol. , vol.10 , pp. 333-338
    • Conley, P.B.1    Delaney, S.M.2
  • 86
    • 0037588974 scopus 로고    scopus 로고
    • Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues Cys17 And Cys270
    • Ding, Z.; Kim, S.; Dorsam, R.T.; Jin, J.; Kunapuli, S.P. Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270. Blood, 2003, 101, 3908-3914.
    • (2003) Blood , vol.101 , pp. 3908-3914
    • Ding, Z.1    Kim, S.2    Dorsam, R.T.3    Jin, J.4    Kunapuli, S.P.5
  • 89
    • 0034622539 scopus 로고    scopus 로고
    • Double-blind study of the safety of clopidogrel with without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting
    • Bertrand, M. E.; Rupprecht, H. J.; Urban, P.; Gershlic, A. H. Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting. Circulation, 2000, 102, 624-629
    • (2000) Circulation , vol.102 , pp. 624-629
    • Bertrand, M.E.1    Rupprecht, H.J.2    Urban, P.3    Gershlic, A.H.4
  • 91
    • 0033941958 scopus 로고    scopus 로고
    • Reduction in the need for hospitalization for recurrent ischemic events and bleeding with clopidogrel instead of aspirin
    • Bhatt, D.L.; Hirsch, A.T.; Ringleb, P.A.; Hacke, W.; Topol, E.J. Reduction in the need for hospitalization for recurrent ischemic events and bleeding with clopidogrel instead of aspirin. Am. Heart J., 2000, 140, 67-73.
    • (2000) Am. Heart J. , vol.140 , pp. 67-73
    • Bhatt, D.L.1    Hirsch, A.T.2    Ringleb, P.A.3    Hacke, W.4    Topol, E.J.5
  • 92
    • 0037106972 scopus 로고    scopus 로고
    • Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus
    • Bhatt, D. L.; Marso, S.P.; Hirsch, A.T.; Ringleb, P. A.; Hacke, W.; Topol, E. J. Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus. Am. J. Cardiol., 2002, 90, 625-628.
    • (2002) Am. J. Cardiol. , vol.90 , pp. 625-628
    • Bhatt, D.L.1    Marso, S.P.2    Hirsch, A.T.3    Ringleb, P.A.4    Hacke, W.5    Topol, E.J.6
  • 93
    • 0035936484 scopus 로고    scopus 로고
    • Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery
    • Bhatt, D. L.; Chew, D. P.; Hirsch, A. T.; Ringleb, P. A.; Hacke, W.; Topol, E. J. Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery. Circulation. 2001, 103, 363-368.
    • (2001) Circulation. , vol.103 , pp. 363-368
    • Bhatt, D.L.1    Chew, D.P.2    Hirsch, A.T.3    Ringleb, P.A.4    Hacke, W.5    Topol, E.J.6
  • 94
    • 0842310777 scopus 로고    scopus 로고
    • Benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic events
    • Ringleb, P.A.; Bhatt, D.L.; Hirsch, A.T.; Topol, E. J.; Hacke, W. benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic events. Stroke, 2004, 35, 528-532.
    • (2004) Stroke , vol.35 , pp. 528-532
    • Ringleb, P.A.1    Bhatt, D.L.2    Hirsch, A.T.3    Topol, E.J.4    Hacke, W.5
  • 95
    • 36849074168 scopus 로고    scopus 로고
    • Prasugrel: A novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile
    • Jakubowski, J. A.; Winters, K. J.; Naganuma, H.; Wallentin, L. Prasugrel: A novel thienopyridine antiplatelet agent. A review of preclinical and clinical studies and the mechanistic basis for its distinct antiplatelet profile. Cardiovasc. Drug Rev., 2007, 25, 357-374.
    • (2007) Cardiovasc. Drug Rev. , vol.25 , pp. 357-374
    • Jakubowski, J.A.1    Winters, K.J.2    Naganuma, H.3    Wallentin, L.4
  • 96
    • 37849002889 scopus 로고    scopus 로고
    • Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
    • Wallentin, L.; Varenhorst, C.; James, S. Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur. Heart J., 2008, 29, 21-30.
    • (2008) Eur. Heart J. , vol.29 , pp. 21-30
    • Wallentin, L.1    Varenhorst, C.2    James, S.3
  • 97
    • 36348977461 scopus 로고    scopus 로고
    • Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel
    • Payne, C. D.; Li, Y. G.; Small, D. S. Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel. J. Cardiovasc. Pharmacol., 2007, 50, 555-562.
    • (2007) J. Cardiovasc. Pharmacol. , vol.50 , pp. 555-562
    • Payne, C.D.1    Li, Y.G.2    Small, D.S.3
  • 98
    • 34249053105 scopus 로고    scopus 로고
    • The disposition of prasugrel, a novel thienopyridine, in humans
    • Farid, N. A.; Smith, R. L.; Gillespie, T. A. The disposition of prasugrel, a novel thienopyridine, in humans. Drug Metab. Dispos., 2007, 35, 1096-1104.
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1096-1104
    • Farid, N.A.1    Smith, R.L.2    Gillespie, T.A.3
  • 99
    • 34250714831 scopus 로고    scopus 로고
    • The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite
    • Sugidachi, A. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J. Thromb Haemost., 2007, 5, 1545-1551.
    • (2007) J. Thromb Haemost. , vol.5 , pp. 1545-1551
    • Sugidachi, A.1
  • 100
    • 33845451677 scopus 로고    scopus 로고
    • A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation
    • 66
    • Brandt, J. T. A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation. Am. Heart J., 2007, 153(1), 66, e9-16.
    • (2007) Am. Heart J. , vol.153 , Issue.1
    • Brandt, J.T.1
  • 101
    • 33646732608 scopus 로고    scopus 로고
    • Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease Eur
    • Jernberg, T. Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease Eur. Heart J., 2006, 27, 1166-1173.
    • (2006) Heart J. , vol.27 , pp. 1166-1173
    • Jernberg, T.1
  • 102
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versul clopidogrel in patient with acute coronary syndromes
    • Wiviott, S. D.; Braunwald, E.; Angiodillo, D. J. Prasugrel versul clopidogrel in patient with acute coronary syndromes. N. Eng. J. Med., 2007, 357, 2001-2015.
    • (2007) N. Eng. J. Med. , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    Angiodillo, D.J.3
  • 103
    • 37349111065 scopus 로고    scopus 로고
    • Prasugrel compared with high loading-and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention
    • Wiviott, S. D. Prasugrel compared with high loading-and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention. Circulation, 2007, 116, 2923-2932.
    • (2007) Circulation , vol.116 , pp. 2923-2932
    • Wiviott, S.D.1
  • 104
    • 67651173161 scopus 로고    scopus 로고
    • Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial
    • Michelson, A. D. Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial. Eur. Heart J., 2009, 30, 1753-1763.
    • (2009) Eur. Heart J. , vol.30 , pp. 1753-1763
    • Michelson, A.D.1
  • 105
    • 0001281595 scopus 로고    scopus 로고
    • Investigation of the novel P2T receptor antagonist AR C69931MX on ex vivo adenosine diphosphate induced platelet aggregation and bleeding time in healthy volunteers
    • SA, p: 255A
    • Nassim, M. A.; Sanderson, J. B.; Clarke, C. Investigation of the novel P2T receptor antagonist AR C69931MX on ex vivo adenosine diphosphate induced platelet aggregation and bleeding time in healthy volunteers. J. Am. Coll. Cardiol., 1999, 33(2), SA, p: 255A.
    • (1999) J. Am. Coll. Cardiol. , vol.33 , Issue.2
    • Nassim, M.A.1    Sanderson, J.B.2    Clarke, C.3
  • 106
    • 0032589747 scopus 로고    scopus 로고
    • Antagonists of the platelet P2T receptor: A novel approach to antithrombotic therapy
    • Ingall, A.H.; Dixon, J.; Bailey, A. Antagonists of the platelet P2T receptor: A novel approach to antithrombotic therapy. J. Med. Chem., 1999, 42, 213-220.
    • (1999) J. Med. Chem. , vol.42 , pp. 213-220
    • Ingall, A.H.1    Dixon, J.2    Bailey, A.3
  • 107
    • 0033781969 scopus 로고    scopus 로고
    • Prevention of arterial thrombosis by intravenously administered platelet P2T receptor antagonist AR-C69931MX in a canine model
    • Huang, J.; Driscoll, E. M.; Gonzales, M. L. Prevention of Arterial Thrombosis by Intravenously Administered Platelet P2T Receptor Antagonist AR-C69931MX in a Canine Model J. Pharmacol. Exp. Ther., 2000, 295, 492-499.
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 492-499
    • Huang, J.1    Driscoll, E.M.2    Gonzales, M.L.3
  • 108
    • 18044388905 scopus 로고    scopus 로고
    • Preclinical and clinical studies with selective reversible direct P2Y12 antagonist
    • van Giezen, J. J.; Humphries, R. G. Preclinical and clinical studies with selective reversible direct P2Y12 antagonist. Thromb Hemost., 2005, 31, 195-204.
    • (2005) Thromb Hemost. , vol.31 , pp. 195-204
    • Van Giezen, J.J.1    Humphries, R.G.2
  • 109
    • 33846817108 scopus 로고    scopus 로고
    • AZD6140. Expert Opin. Investig
    • Tantry, U. S.; Bliden, K. P.; Gurbel, P. A. AZD6140. Expert Opin. Investig. Drugs, 2007, 16, 225-229.
    • (2007) Drugs , vol.16 , pp. 225-229
    • Tantry, U.S.1    Bliden, K.P.2    Gurbel, P.A.3
  • 110
    • 33646261670 scopus 로고    scopus 로고
    • Pharmacodynamics pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin
    • Husted, S. Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin Eur. Heart J., 2006, 27, 1038-1047.
    • (2006) Eur. Heart J. , vol.27 , pp. 1038-1047
    • Husted, S.1
  • 111
    • 35548995394 scopus 로고    scopus 로고
    • Safety tolerability and initial efficacy of AZD6140 the first reversible oral adenosine diphosphate receptor antagonist compared with clopidogrel in patients with non-ST-Segment elevation acute coronary syndrome
    • Cannon, C. P. Safety, Tolerability, and Initial Efficacy of AZD6140, the First Reversible Oral Adenosine Diphosphate Receptor Antagonist, Compared With Clopidogrel, in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. J. Am. Coll. Cardiol., 2007, 50, 1844-1851.
    • (2007) J. Am. Coll. Cardiol. , vol.50 , pp. 1844-1851
    • Cannon, C.P.1
  • 112
    • 35548933800 scopus 로고    scopus 로고
    • Inhibition of platelet aggregation by AZD6140 a reversible oral P2Y12 receptor antagonist compared with clopidogrel in patients with acute coronary syndromes
    • Storey, R. F. Inhibition of Platelet Aggregation by AZD6140, A Reversible Oral P2Y12 Receptor Antagonist, Compared With Clopidogrel in Patients With Acute Coronary Syndromes. J. Am. Coll. Cardiol., 2007, 50, 1852-1856.
    • (2007) J. Am. Coll. Cardiol. , vol.50 , pp. 1852-1856
    • Storey, R.F.1
  • 113
  • 114
  • 116
    • 0030999134 scopus 로고    scopus 로고
    • Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics
    • Coller, B. S. Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics. J. Clin. Invest., 1997, 99, 1467-1471.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1467-1471
    • Coller, B.S.1
  • 117
    • 0031041549 scopus 로고    scopus 로고
    • In vitro effects of the platelet glycoprotein iib/iiia receptor antagonist c7e3 fab on the activated clotting time
    • Ammar, T.; Scudder, L. E.; Coller, B. S. In vitro effects of the platelet glycoprotein iib/iiia receptor antagonist c7e3 fab on the activated clotting time. Circulation, 1997, 95, 614-617.
    • (1997) Circulation , vol.95 , pp. 614-617
    • Ammar, T.1    Scudder, L.E.2    Coller, B.S.3
  • 118
    • 0029914728 scopus 로고    scopus 로고
    • Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis"
    • Reverter, J. C. Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis". J. Clin. Invest., 1996, 98, 863-874.
    • (1996) J. Clin. Invest. , vol.98 , pp. 863-874
    • Reverter, J.C.1
  • 119
    • 0033828457 scopus 로고    scopus 로고
    • GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood
    • Furman, M. I. GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood. Thromb. Haemost., 2000, 84, 492-498.
    • (2000) Thromb. Haemost. , vol.84 , pp. 492-498
    • Furman, M.I.1
  • 120
    • 0030870212 scopus 로고    scopus 로고
    • Networking in the Hemostatic System. Intergrin aIIbb3 binds prothrombin and influences its activation
    • Byzova, T. V.; Plow, E. F. Networking in the Hemostatic System. Intergrin aIIbb3 binds prothrombin and influences its activation J. Biol. Chem., 1997, 272, 27183-27188.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27183-27188
    • Byzova, T.V.1    Plow, E.F.2
  • 121
    • 33646568098 scopus 로고    scopus 로고
    • Antiplatelet therapy: Current strategies and future trends
    • Udaya, S. T.; Amena, E.; Kevin, P. B.; Paul, A. G. Antiplatelet therapy: Current strategies and future trends. Future Cardiol., 2006, 2(3), 343-366.
    • (2006) Future Cardiol. , vol.2 , Issue.3 , pp. 343-366
    • Udaya, S.T.1    Amena, E.2    Kevin, P.B.3    Paul, A.G.4
  • 122
    • 0032586318 scopus 로고    scopus 로고
    • New thrombolytics anticoagulants and platelet antagonists: The future of clinical practice
    • Richard, C. B. New Thrombolytics, Anticoagulants, and Platelet Antagonists: The Future of Clinical Practice. J. Thromb Thrombolysis., 1999, 7, 195-220.
    • (1999) J. Thromb Thrombolysis. , vol.7 , pp. 195-220
    • Richard, C.B.1
  • 123
    • 43149088638 scopus 로고    scopus 로고
    • 2nd Edn. Elsevier/Academic Press, San Diego
    • Agah, R.; Plow, E. F.; Topol, E. J. Platelets, 2nd edn. Elsevier/Academic Press, San Diego, 2007, 1145-1163.
    • (2007) Platelets , pp. 1145-1163
    • Agah, R.1    Plow, E.F.2    Topol, E.J.3
  • 124
    • 0032420213 scopus 로고    scopus 로고
    • Combining thrombolysis with the platelet glycoprotein IIb/IIIa inhibitor lamifiban: Results of the Platelet Aggregation Receptor Antagonist Dose Investigation and reperfusion Gain in Myocardial infarction (PARADIGM) trial
    • PARADIGM Investigators.
    • PARADIGM Investigators. Combining thrombolysis with the platelet glycoprotein IIb/IIIa inhibitor lamifiban: Results of the Platelet Aggregation Receptor Antagonist Dose Investigation and reperfusion Gain in Myocardial infarction (PARADIGM) trial. J. Am. Coll. Cardiol., 1998, 32, 2003-2010.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 2003-2010
  • 125
    • 0342872079 scopus 로고    scopus 로고
    • Profound and sustained inhibition of platelet aggregation by fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, lefradafiban, in men
    • Muller, T. H.; Weisenberger, H.; Brickl, R.; Narjes, H.; Himmelsbach, F.; Krause, J.; Profound and sustained inhibition of platelet aggregation by fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, lefradafiban, in men. Circulation, 1997, 96, 1130-1138.
    • (1997) Circulation , vol.96 , pp. 1130-1138
    • Muller, T.H.1    Weisenberger, H.2    Brickl, R.3    Narjes, H.4    Himmelsbach, F.5    Krause, J.6
  • 126
    • 9044234402 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIbIIIa blockade in high risk patients undergoing coronary angioplasty
    • Kereiakes, D. J.; Kleiman, N. S.; Ambrose, J.; Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIb/IIIa blockade in high risk patients undergoing coronary angioplasty J. Am. Coll. Cardiol., 1996, 27, 536-542.
    • (1996) J. Am. Coll. Cardiol. , vol.27 , pp. 536-542
    • Kereiakes, D.J.1    Kleiman, N.S.2    Ambrose, J.3
  • 127
    • 0030863733 scopus 로고    scopus 로고
    • Clinical pharmacology of eptifibatide
    • Phillips, D. R.; Scarborough, R. M. Clinical pharmacology of eptifibatide. Am. J. Cardiol., 1997, 80(4A), 11B-20B.
    • (1997) Am. J. Cardiol. , vol.80 , Issue.4 A
    • Phillips, D.R.1    Scarborough, R.M.2
  • 131
    • 0033669093 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmaco dynamics of sibrafiban, an orally administered GP IIb/IIIa antagonist, following coadministration of aspirin and heparin
    • Reimann, J. D.; Modi, N. B.; Novotny, W. Pharmacokinetics and pharmaco dynamics of sibrafiban, an orally administered GP IIb/IIIa antagonist, following coadministration of aspirin and heparin. J. Clin. Pharmacol., 2000, 40(5), 488-495.
    • (2000) J. Clin. Pharmacol. , vol.40 , Issue.5 , pp. 488-495
    • Reimann, J.D.1    Modi, N.B.2    Novotny, W.3
  • 134
    • 84894015267 scopus 로고    scopus 로고
    • Lotrafiban-SmithKline Beecham: An oral platelet glycoprotein IIb/IIIa blocker and related issues
    • Fengqi, L.; Robert, M. C.; Steve, A. M.; Roger, C. C. Lotrafiban-SmithKline Beecham: An oral platelet glycoprotein IIb/IIIa blocker and related issues. Expert Opin. Investig. Drugs., 2000, 9(11), 2673-2687.
    • (2000) Expert Opin. Investig. Drugs. , vol.9 , Issue.11 , pp. 2673-2687
    • Fengqi, L.1    Robert, M.C.2    Steve, A.M.3    Roger, C.C.4
  • 135
    • 0035035790 scopus 로고    scopus 로고
    • A population pharmacokinetic-pharmacodynamic and logistic regression analysis of lotrafiban in patients
    • Mould, D.; Chapelsky, M.; Aluri, J.; Swagzdis, J.; Samuels, R.; Granett, J. A population pharmacokinetic-pharmacodynamic and logistic regression analysis of lotrafiban in patients. Clin. Pharmacol. Ther., 2001, 69(4), 210-222.
    • (2001) Clin. Pharmacol. Ther. , vol.69 , Issue.4 , pp. 210-222
    • Mould, D.1    Chapelsky, M.2    Aluri, J.3    Swagzdis, J.4    Samuels, R.5    Granett, J.6
  • 139
    • 0032957249 scopus 로고    scopus 로고
    • The antithrombotic efficacy of the GP IIb/IIIa antagonist SR121787 is potentiated by antithrombin-dependent factor Xa inhibition without an increase in the bleeding risk in the rabbit
    • Bernat, A.; Savi, P.; Lale, A.; Hoffmann, P.; Herbert, J. M. The antithrombotic efficacy of the GP IIb/IIIa antagonist SR121787 is potentiated by antithrombin-dependent factor Xa inhibition without an increase in the bleeding risk in the rabbit. J. Cardiovasc. Pharmacol., 1999, 33(4), 573-579.
    • (1999) J. Cardiovasc. Pharmacol. , vol.33 , Issue.4 , pp. 573-579
    • Bernat, A.1    Savi, P.2    Lale, A.3    Hoffmann, P.4    Herbert, J.M.5
  • 141
    • 0035140978 scopus 로고    scopus 로고
    • The effect of a novel glycoprotein IIb/IIIa antagonist, SR 121566A, on platelet aggregation and activation in rhesus monkeys
    • Mark, K. O. S.; Justin, H.; Debra, A. H.; Walter, J.; Jean, M. H.; Jawed, F. The effect of a novel glycoprotein IIb/IIIa antagonist, SR 121566A, on platelet aggregation and activation in rhesus monkeys. Clin. Appl. Thromb Hemost., 2001, 7(1), 10-15.
    • (2001) Clin. Appl. Thromb Hemost. , vol.7 , Issue.1 , pp. 10-15
    • Mark, K.O.S.1    Justin, H.2    Debra, A.H.3    Walter, J.4    Jean, M.H.5    Jawed, F.6
  • 142
    • 0034745015 scopus 로고    scopus 로고
    • Synergistic induction of tissue-type plasminogen activator (tPA) by vascular endothelial growth factor and basic fibroblast growth factor and localization of tPA to Weibel-Palade bodies in bovine micr ovascular endothelial cells
    • Savi, P.; Zamboni, G.; Rescanières, O.; Herbert, J. M. Synergistic induction of tissue-type plasminogen activator (tPA) by vascular endothelial growth factor and basic fibroblast growth factor and localization of tPA to Weibel-Palade bodies in bovine micr ovascular endothelial cells. Thromb. Haemost., 2001, 85(4), 702-709.
    • (2001) Thromb. Haemost. , vol.85 , Issue.4 , pp. 702-709
    • Savi, P.1    Zamboni, G.2    Rescanières, O.3    Herbert, J.M.4
  • 144
    • 0033371222 scopus 로고    scopus 로고
    • Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 2. Condensed heterocyclic derivatives
    • Ono, S.; Yoshida, T.; Maeda, K.; Kosaka, K.; Inoue, Y.; Imada, T.; Fukaya, C.; Nakamura, N. Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 2. Condensed heterocyclic derivatives. Chem. Pharm. Bull. (Tokyo), 1999, 47(12), 1694-1712.
    • (1999) Chem. Pharm. Bull. (Tokyo) , vol.47 , Issue.12 , pp. 1694-1712
    • Ono, S.1    Yoshida, T.2    Maeda, K.3    Kosaka, K.4    Inoue, Y.5    Imada, T.6    Fukaya, C.7    Nakamura, N.8
  • 148
    • 0031837220 scopus 로고    scopus 로고
    • Expression of ligandinduced binding sites on glycoprotein IIb/IIIa complexes and effect of various inhibitors
    • Jennings, L. K.; Melanie, M.; White, B. A. Expression of ligandinduced binding sites on glycoprotein IIb/IIIa complexes and effect of various inhibitors. Amereican Heart Journal, 1998, Suppl.1, S179-S183.
    • (1998) Amereican Heart Journal , Issue.SUPPL. 1
    • Jennings, L.K.1    Melanie, M.2    White, B.A.3
  • 150
    • 0037188668 scopus 로고    scopus 로고
    • Activating effects of GPIIb/IIIa blockers: An intrinsic consequence of ligand-mimetic properties
    • Peter, K.; Schwarz, M.; Bode, C. Activating Effects of GPIIb/IIIa Blockers: An Intrinsic Consequence of Ligand-Mimetic Properties. Circulation. 2002, 105, e180-e181.
    • (2002) Circulation. , vol.105
    • Peter, K.1    Schwarz, M.2    Bode, C.3
  • 151
    • 0014190795 scopus 로고
    • Impaired platelet-connective-tissue reaction in man after aspirin ingestion
    • Weiss, H. J.; Aledort, L. M. Impaired platelet-connective-tissue reaction in man after aspirin ingestion. Lancet., 1967, 2, 495-497.
    • (1967) Lancet. , vol.2 , pp. 495-497
    • Weiss, H.J.1    Aledort, L.M.2
  • 152
    • 0016805004 scopus 로고
    • The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein
    • Roth, G. J.; Majerus, P. W. The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein. J. Clin. Invest., 1975, 56, 624-632.
    • (1975) J. Clin. Invest. , vol.56 , pp. 624-632
    • Roth, G.J.1    Majerus, P.W.2
  • 155
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane, J. R. Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs. Nat. New Biol., 1971, 231, 232-235.
    • (1971) Nat. New Biol. , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 157
    • 0029056992 scopus 로고
    • The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
    • Loll, P. J.; Picot, D.; Garavito, R. M. The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase. Nat. Struct. Biol., 1995, 2, 637-643.
    • (1995) Nat. Struct. Biol. , vol.2 , pp. 637-643
    • Loll, P.J.1    Picot, D.2    Garavito, R.M.3
  • 158
    • 0035124920 scopus 로고    scopus 로고
    • Platelet-active drugs: The relationships among dose, effectiveness, and side effects
    • Patrono, C.; Coller, B.; Dalen, J. E. Platelet-active drugs: The relationships among dose, effectiveness, and side effects. Chest, 2001, 119(Suppl. 1), S39-S63.
    • (2001) Chest , vol.119 , Issue.SUPPL. 1
    • Patrono, C.1    Coller, B.2    Dalen, J.E.3
  • 159
    • 0022374695 scopus 로고
    • Cyclooxygenase inhibition, platelet function and metabolite formation during chronic sulfinpyrazone dosing
    • Pedersen, A. K.; Fitz-Gerald, G. A. Cyclooxygenase inhibition, platelet function and metabolite formation during chronic sulfinpyrazone dosing. Clin. Pharmacol. Ther., 1985, 37, 36-42.
    • (1985) Clin. Pharmacol. Ther. , vol.37 , pp. 36-42
    • Pedersen, A.K.1    Fitz-Gerald, G.A.2
  • 160
    • 0025310233 scopus 로고
    • Effects of indobufen on platelet thromboxane B2 production in patients with myocardial infarction
    • Rebuzzi, A. G.; Natale, A.; Bianchi, C. Effects of indobufen on platelet thromboxane B2 production in patients with myocardial infarction. Eur. J. Clin. Pharmacol., 1990, 39, 99-100.
    • (1990) Eur. J. Clin. Pharmacol. , vol.39 , pp. 99-100
    • Rebuzzi, A.G.1    Natale, A.2    Bianchi, C.3
  • 161
    • 0033670105 scopus 로고    scopus 로고
    • Ridogrel: An antiplatelet agent with antihypertensive properties
    • Thomas, W. W.; Dale, W. Q. Ridogrel: An Antiplatelet Agent with Antihypertensive Properties. Cardiovasc. Drug Rev., 2000, 18(3), 222-231.
    • (2000) Cardiovasc. Drug Rev. , vol.18 , Issue.3 , pp. 222-231
    • Thomas, W.W.1    Dale, W.Q.2
  • 162
    • 0026591175 scopus 로고
    • Ridogrel: A selective inhibitor of the cytochrome P450-dependent thromboxane synthesis
    • Bossche, H.V.; Willemsens, G.; Bellens, D.; Janssen, P.A.J. Ridogrel: A selective inhibitor of the cytochrome P450-dependent thromboxane synthesis. Biochem. Pharmacol., 1992, 43(4), 739-744.
    • (1992) Biochem. Pharmacol. , vol.43 , Issue.4 , pp. 739-744
    • Bossche, H.V.1    Willemsens, G.2    Bellens, D.3    Janssen, P.A.J.4
  • 163
    • 0032951722 scopus 로고    scopus 로고
    • In vivo antithrombotic effects of a nitric oxidereleasing aspirin derivative, NCX-4016
    • Wallace, J. L. In vivo antithrombotic effects of a nitric oxidereleasing aspirin derivative, NCX-4016. Thromb. Res., 1999, 93, 43-50.
    • (1999) Thromb. Res. , vol.93 , pp. 43-50
    • Wallace, J.L.1
  • 164
    • 6944234992 scopus 로고    scopus 로고
    • Antithrombotic effects of S 18886, a novel orally active thromboxane A2 receptor antagonist
    • Osende, J. I.; Shimbo, D.; Fuster, V.; Dubar, M.; Badimon, J, J. Antithrombotic effects of S 18886, a novel orally active thromboxane A2 receptor antagonist. J. Thromb. Haemost. 2004, 2, 492-498.
    • (2004) J. Thromb. Haemost. , vol.2 , pp. 492-498
    • Osende, J.I.1    Shimbo, D.2    Fuster, V.3    Dubar, M.4    Badimon J, J.5
  • 165
    • 84894016655 scopus 로고
    • Dazoxiben
    • Dazoxiben. The Lancet. 1983, 321, 627-628.
    • (1983) The Lancet. , vol.321 , pp. 627-628
  • 166
    • 0021930774 scopus 로고
    • Effects of dazoxiben, an inhibitor of thromboxane synthetase, on forearm vasoconstriction in response to cold stimulation, and on human blood vessel prostacyclin production
    • Cowley, A. J.; Jones, E. W.; Carter, A. J.; Hanley, S. P.; Heptinstall, S. Effects of dazoxiben, an inhibitor of thromboxane synthetase, on forearm vasoconstriction in response to cold stimulation, and on human blood vessel prostacyclin production. Br. J. Clin. Pharmacol., 1985, 19, 1-8.
    • (1985) Br. J. Clin. Pharmacol. , vol.19 , pp. 1-8
    • Cowley, A.J.1    Jones, E.W.2    Carter, A.J.3    Hanley, S.P.4    Heptinstall, S.5
  • 168
    • 0024348514 scopus 로고
    • GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro
    • Lumley, P.; White, B. P.; Humphrey, P. P. GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro. Br. J. Pharmacol., 1989, 97(3), 783-794.
    • (1989) Br. J. Pharmacol. , vol.97 , Issue.3 , pp. 783-794
    • Lumley, P.1    White, B.P.2    Humphrey, P.P.3
  • 169
    • 34249856927 scopus 로고    scopus 로고
    • A review of picotamide in the reduction of cardiovascular events in diabetic patients
    • Andrea, C.; Francesco, V. A review of picotamide in the reduction of cardiovascular events in diabetic patients. Vasc. Health Risk Manag., 2007, 3(1), 93-98.
    • (2007) Vasc. Health Risk Manag. , vol.3 , Issue.1 , pp. 93-98
    • Andrea, C.1    Francesco, V.2
  • 170
    • 4944241267 scopus 로고    scopus 로고
    • Picotamide a combined inhibitor of thromboxane A2 synthase and receptor reduces 2-year mortality in diabetics with peripheral arterial disease: The DAVID study
    • Gian, G.; Neri, S.; Sergio, C.; Ettore, M.; Francesco, V. Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: The DAVID study. Eur. Heart J., 2004, 25(20), 1845-1852.
    • (2004) Eur. Heart J. , vol.25 , Issue.20 , pp. 1845-1852
    • Gian, G.1    Neri, S.2    Sergio, C.3    Ettore, M.4    Francesco, V.5
  • 172
    • 33748307543 scopus 로고    scopus 로고
    • Comparison of the effects of PAR1 antagonists, PAR4 antagonists, and their combinations on thrombin-induced human platelet activation
    • Wu, C. C.; Teng, C. M. Comparison of the effects of PAR1 antagonists, PAR4 antagonists, and their combinations on thrombin-induced human platelet activation. Eur. J. Pharmacol., 2006, 546 (1-3), 142-147.
    • (2006) Eur. J. Pharmacol. , vol.546 , Issue.1-3 , pp. 142-147
    • Wu, C.C.1    Teng, C.M.2
  • 173
    • 0033943590 scopus 로고    scopus 로고
    • YD-3 a novel inhibitor of protease-induced platelet activation
    • Wu, C, C.; Huang, S. W.; Hwang, T. L. YD-3, a novel inhibitor of protease-induced platelet activation. Br. J. Pharmacol., 2000, 130(6), 1289-1296.
    • (2000) Br. J. Pharmacol. , vol.130 , Issue.6 , pp. 1289-1296
    • Wu C, C.1    Huang, S.W.2    Hwang, T.L.3
  • 174
    • 34248371253 scopus 로고    scopus 로고
    • Clinical aspects of platelet inhibitors thrombus formation
    • Meadows, T. A.; Bhatt, D. L. Clinical Aspects of Platelet Inhibitors and Thrombus Formation. Circ. Res., 2007, 100(9), 1261-1275
    • (2007) Circ. Res. , vol.100 , Issue.9 , pp. 1261-1275
    • Meadows, T.A.1    Bhatt, D.L.2
  • 175
    • 0037310962 scopus 로고    scopus 로고
    • Blockade of the thrombin receptor protease-activated receptor-1 with a small-molecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates
    • Derian, C. K.; Damiano, B. P.; Addo, M. F. Blockade of the Thrombin Receptor Protease-Activated Receptor-1 with a Small-Molecule Antagonist Prevents Thrombus Formation and Vascular Occlusion in Nonhuman Primates. J. Pharmacol. Exp. Ther., 2003, 304(2), 855-861.
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , Issue.2 , pp. 855-861
    • Derian, C.K.1    Damiano, B.P.2    Addo, M.F.3
  • 176
    • 0348050052 scopus 로고    scopus 로고
    • Blockade of the thrombin receptor protease-activated receptor-1 with a small-molecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates
    • Damiano, B. P.; Derian, C. K.; Maryanoff, B. E. Blockade of the Thrombin Receptor Protease-Activated Receptor-1 with a Small-Molecule Antagonist Prevents Thrombus Formation and Vascular Occlusion in Nonhuman Primates. Cardiovasc.
    • (2003) Cardiovasc. Drug Rev. , vol.21 , Issue.4 , pp. 313-326
    • Damiano, B.P.1    Derian, C.K.2    Maryanoff, B.E.3
  • 177
    • 33748629116 scopus 로고    scopus 로고
    • Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs cardiovasc
    • De Mayer, S. F.; Vanhoorelbeke, K.; lrichts, H.; Staelens, S.; Feys, H. B.; Salles, I. Development of Monoclonal Antibodies that Inhibit Platelet Adhesion or Aggregation as Potential Anti-Thrombotic Drugs Cardiovasc. Hematol. Disord. Drug Targets, 2006, 6, 191-206.
    • (2006) Hematol. Disord. Drug Targets , vol.6 , pp. 191-206
    • De Mayer, S.F.1    Vanhoorelbeke, K.2    Lrichts, H.3    Staelens, S.4    Feys, H.B.5    Salles, I.6
  • 178
    • 0842328842 scopus 로고    scopus 로고
    • Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood
    • Siljander, P. R.; Munnix, I. C.; Smethurst, P. A.; Deckmyn, H.; Linhout, T.; Quwehand, W. H. Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood. Blood, 2004, 103, 1333-1341.
    • (2004) Blood , vol.103 , pp. 1333-1341
    • Siljander, P.R.1    Munnix, I.C.2    Smethurst, P.A.3    Deckmyn, H.4    Linhout, T.5    Quwehand, W.H.6
  • 179
    • 13244275108 scopus 로고    scopus 로고
    • Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans
    • Hubbard, G. P.; Wolffram, S.; de Vos, R.; Bovy, A.; Gibbins, J. M. Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans. J. Thromb. Haemost., 2004, 2, 2138-2145.
    • (2004) J. Thromb. Haemost. , vol.2 , pp. 2138-2145
    • Hubbard, G.P.1    Wolffram, S.2    De Vos, R.3    Bovy, A.4    Gibbins, J.M.5
  • 180
    • 0025861078 scopus 로고
    • A potent antiplatelet peptide, triflavin, from Trimeresurus flavoviridis snake venom
    • Huang, T. F.; Sheu, J. R.; Teng, C. M. A potent antiplatelet peptide, triflavin, from Trimeresurus flavoviridis snake venom. Biochem. J., 1991, 277, 351-357.
    • (1991) Biochem. J. , vol.277 , pp. 351-357
    • Huang, T.F.1    Sheu, J.R.2    Teng, C.M.3
  • 181
    • 0027732243 scopus 로고
    • A hypotensive procyanidin-glycoside from Rhamnus formosana
    • Teng, C. M.; Lin, C. H.; Lin, C. N.; Chung, M. I.; Haung, T. F. A hypotensive procyanidin-glycoside from Rhamnus formosana. Thromb Haemost., 1993, 70, 1014-1018.
    • (1993) Thromb Haemost. , vol.70 , pp. 1014-1018
    • Teng, C.M.1    Lin, C.H.2    Lin, C.N.3    Chung, M.I.4    Haung, T.F.5
  • 182
    • 22444435682 scopus 로고    scopus 로고
    • A new compound with effects on arachidonic acid metabolites
    • Molina, V.; Carbajal, D.; Arruzazabala, L.; Mas R. A new compound with effects on arachidonic acid metabolites. J. Med. Food., 2005, 8, 232-236.
    • (2005) J. Med. Food. , vol.8 , pp. 232-236
    • Molina, V.1    Carbajal, D.2    Arruzazabala, L.3    Mas, R.4
  • 183
    • 34547725681 scopus 로고    scopus 로고
    • Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: In vitro and in vivo studies
    • Haiso, G.; Lee, J. J.; Lin, K. H.; Shen, C. H.; Fong, T. H.; Chou, D. S. Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: In vitro and in vivo studies. Cardiovasc. Res., 2007, 75, 782-792.
    • (2007) Cardiovasc. Res. , vol.75 , pp. 782-792
    • Haiso, G.1    Lee, J.J.2    Lin, K.H.3    Shen, C.H.4    Fong, T.H.5    Chou, D.S.6
  • 184
    • 0027212250 scopus 로고
    • Echicetin: A snake venom protein that inhibits binding of von Willebrand factor and alboaggregins to platelet glycoprotein Ib
    • Peng, M. L.; Lu, W. Q.; Beviglia, L.; Niewiarowski, S.; Kirby, E. P. Echicetin: A snake venom protein that inhibits binding of von Willebrand factor and alboaggregins to platelet glycoprotein Ib. Blood, 1993, 81, 2321-2328.
    • (1993) Blood , vol.81 , pp. 2321-2328
    • Peng, M.L.1    Lu, W.Q.2    Beviglia, L.3    Niewiarowski, S.4    Kirby, E.P.5
  • 185
    • 0035127166 scopus 로고    scopus 로고
    • Pharmacological characterization and antithrombotic effect of agkistin, a platelet glycoprotein Ib antagonist
    • Yeh, C. H.; Chang, M. C.; Peng, H. C.; Huang, T. F. Pharmacological characterization and antithrombotic effect of agkistin, a platelet glycoprotein Ib antagonist. Br. J. Pharmacol., 2001, 132, 843-850.
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 843-850
    • Yeh, C.H.1    Chang, M.C.2    Peng, H.C.3    Huang, T.F.4
  • 186
    • 29944447636 scopus 로고    scopus 로고
    • Characterization and molecular cloning of dabocetin, a potent antiplatelet C-type lectin-like protein from Daboia russellii siamensis venom
    • Zhong, S. R.; Jin, Y.; Wu, J. B.; Chen, R. Q.; Jia, Y. H.; Wang, W. Y.; Xiong, Y. L.; Zhang, Y. Characterization and molecular cloning of dabocetin, a potent antiplatelet C-type lectin-like protein from Daboia russellii siamensis venom. Toxicon, 2006, 47, 104-112.
    • (2006) Toxicon , vol.47 , pp. 104-112
    • Zhong, S.R.1    Jin, Y.2    Wu, J.B.3    Chen, R.Q.4    Jia, Y.H.5    Wang, W.Y.6    Xiong, Y.L.7    Zhang, Y.8
  • 187
    • 0032031490 scopus 로고    scopus 로고
    • Antithrombotic Effect of Crotalin, a Platelet Membrane Glycoprotein Ib Antagonist From Venom of Crotalus atrox
    • Chang, M. C.; Lin, H. K.; Peng, H. C.; Huang, T. F. Antithrombotic Effect of Crotalin, a Platelet Membrane Glycoprotein Ib Antagonist From Venom of Crotalus atrox. Blood, 1998, 91, 1582-1589.
    • (1998) Blood , vol.91 , pp. 1582-1589
    • Chang, M.C.1    Lin, H.K.2    Peng, H.C.3    Huang, T.F.4
  • 188
    • 85013973898 scopus 로고    scopus 로고
    • 2ndedn, Elsevier/Academic Press, San Diego
    • Eisert, W. G. Platelets 2ndedn, Elsevier/Academic Press, San Diego, 2007, 1165-1179.
    • (2007) Platelets , pp. 1165-1179
    • Eisert, W.G.1
  • 189
    • 33645795058 scopus 로고    scopus 로고
    • Inhibition of platelet activation and aggregation
    • Ahrens, I.; Bode, C.; Peter, K. Inhibition of platelet activation and aggregation. Handb. Exp. Pharmacol., 2005, 170, 443-462.
    • (2005) Handb. Exp. Pharmacol. , vol.170 , pp. 443-462
    • Ahrens, I.1    Bode, C.2    Peter, K.3
  • 190
    • 0037335810 scopus 로고    scopus 로고
    • Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: In vitro and in vivo/Ex vivo studies
    • Aktas, B.; Utz, A.; Hoenig-Liedl, P.; Walter, U.; Geiger, J. Dipyridamole Enhances NO/cGMP-Mediated Vasodilator-Stimulated Phosphoprotein Phosphorylation and Signaling in Human Platelets: In Vitro and In Vivo/Ex Vivo Studies. Stroke, 2003, 34, 764-769.
    • (2003) Stroke , vol.34 , pp. 764-769
    • Aktas, B.1    Utz, A.2    Hoenig-Liedl, P.3    Walter, U.4    Geiger, J.5
  • 191
    • 70449501536 scopus 로고    scopus 로고
    • 2nd edn, Elsevier/Academic Press, San Diego
    • Ikeda, Y.; Sudo, T.; Kimura, Y. Platelets 2nd edn, Elsevier/Academic Press, San Diego, 2007, 1181-1191.
    • (2007) Platelets , pp. 1181-1191
    • Ikeda, Y.1    Sudo, T.2    Kimura, Y.3
  • 192
    • 44349138210 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of randomized clinical trials appraising the impact of cilostazol after percutaneous coronary intervention
    • Biondi-Zoccai, G. G. Systematic review and meta-analysis of randomized clinical trials appraising the impact of cilostazol after percutaneous coronary intervention Am. Heart J., 2008, 155, 1081-1089.
    • (2008) Am. Heart J. , vol.155 , pp. 1081-1089
    • Biondi-Zoccai, G.G.1
  • 193
    • 1442319158 scopus 로고    scopus 로고
    • The pharmacology of cilostazol
    • Schror, K. The pharmacology of cilostazol. Diabetes Obes. Metab., 2002, 4(suppl 2), S14-S19.
    • (2002) Diabetes Obes. Metab. , vol.4 , Issue.SUPPL. 2
    • Schror, K.1
  • 195
    • 37349040378 scopus 로고    scopus 로고
    • First-in-Human Evaluation of Anti-von Willebrand Factor Therapeutic Aptamer ARC1779 in Healthy Volunteers
    • Gilbert, J. C.; DeFeo-Fraulini, T.; Hutabarat, R. M. First-in-Human Evaluation of Anti-von Willebrand Factor Therapeutic Aptamer ARC1779 in Healthy Volunteers. Circulation, 2007, 116, 2678-2686.
    • (2007) Circulation , vol.116 , pp. 2678-2686
    • Gilbert, J.C.1    DeFeo-Fraulini, T.2    Hutabarat, R.M.3
  • 196
    • 84894022192 scopus 로고    scopus 로고
    • http://www.clinicaltrials.gov/ct2/show/NCT00507338?term=tra+cer&rank= 1
  • 197
    • 30444437494 scopus 로고    scopus 로고
    • C1qTNF-related protein-1 (CTRP-1): A vascular wall protein that inhibits collagen-induced platelet aggregation by blocking VWF binding to collagen
    • Lasser, G.; Guchhait, P.; Ellsworth, J. L. C1qTNF-related protein-1 (CTRP-1): A vascular wall protein that inhibits collagen-induced platelet aggregation by blocking VWF binding to collagen. Blood, 2006, 107, 423-430.
    • (2006) Blood , vol.107 , pp. 423-430
    • Lasser, G.1    Guchhait, P.2    Ellsworth, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.