Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 2. Condensed heterocyclic derivatives

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 12, 1999, Pages 1694-1712

  Ono, Shin'ichiro ^a   Yoshida, Tomohiro ^a   Maeda, Kazuhiro ^a   Kosaka, Keigo ^b   Inoue, Yoshihisa ^b   Imada, Teruaki ^a   Fukaya, Chikara ^c   Nakamura, Norifumi ^d  

^a Yoshitomi Pharmaceutical Indust   (Japan)

^b Drug Discovery Laboratories   (Japan)

^c Yoshitomi Pharmaceutical Indust L   (Japan)

^d Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

Amidinobenzofuran; AR0510; Glycoprotein IIb IIIa; Structure activity relationship

Indexed keywords

3 [4 (5 AMIDINOBENZOFURAN 2 CARBOXAMIDO)CYCLOHEXYL]PROPIONIC ACID; 3 [4 (5 AMIDINOBENZOFURAN 2 CARBOXAMIDO)CYCLOHEXYL]PROPIONIC ETHYL ESTER; 3 [[4 [[4 (AMINOIMINOMETHYL)PHENYL]AMINO] 1,4 DIOXOBUTYL]AMINO] 4 PENTYNOIC ACID; 4 (5 AMIDINOBENZOFURAN 2 CARBOXAMIDO)CYCLOHEXYLOXYACETIC ACID; 4 (5 AMIDINOBENZOFURAN 2 CARBOXAMIDO)CYCLOHEXYLOXYACETIC ETHYL ESTER; ACETIC ACID DERIVATIVE; ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; BENZOFURAN DERIVATIVE; COLLAGEN; ECHISTATIN; FIBRINOGEN RECEPTOR ANTAGONIST; FRADAFIBAN; HETEROCYCLIC COMPOUND; PHORBOL 13 ACETATE 12 MYRISTATE; PRODRUG; PROPIONIC ACID DERIVATIVE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENDOTHELIUM CELL; GUINEA PIG; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION; THROMBOSIS;

EID: 0033371222     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1694     Document Type: Article

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