Antagonists of the platelet P(2t) receptor: A novel approach to antithrombotic therapy

Journal of Medicinal Chemistry

Volumn 42, Issue 2, 1999, Pages 213-220

  Ingall, Anthony H ^a   Dixon, John ^a   Bailey, Andrew ^a   Coombs, Mandy E ^a   Cox, David ^a   McInally, Judith I ^a   Hunt, Simon F ^a   Kindon, Nicholas D ^a   Teobald, Barry J ^a   Willis, Paul A ^a   Humphries, Robert G ^a   Leff, Paul ^a   Clegg, Jane A ^a   Smith, James A ^a   Tomlinson, Wendy ^a  

^a ASTRA Charnwood ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; AR C 66096MX; AR C 67085MX; AR C 69931MX; FPL 66096MX; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; ADENOSINE PHOSPHATE; ANTITHROMBOCYTIC AGENT; AR C67085MX; CANGRELOR; DRUG DERIVATIVE; MEMBRANE PROTEIN; P2RY12 PROTEIN, HUMAN; PURINE P2Y12 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BLEEDING TIME; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOG; DRUG STRUCTURE; HUMAN; NONHUMAN; NORMAL HUMAN; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION INHIBITION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; THROMBOCYTE; THROMBOSIS;

ADENOSINE MONOPHOSPHATE; BLOOD PLATELETS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; MOLECULAR STRUCTURE; PLATELET AGGREGATION INHIBITORS; RECEPTORS, PURINERGIC P2; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; THROMBOSIS;

EID: 0032589747     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm981072s     Document Type: Article

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