메뉴 건너뛰기




Volumn 7, Issue 2, 1999, Pages 195-220

New thrombolytic, anticoagulants, and platelet antagonists: The future of clinical practice

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; ARDEPARIN; BOXOL; CERTOPARIN; DALTEPARIN; DANAPAROID; DERMATAN SULFATE; ENOXAPARIN; FIBRINOLYTIC AGENT; HEPARINOID; LANOTEPLASE; LOW MOLECULAR WEIGHT HEPARIN; MINIPARIN; NADROPARIN; PARNAPARIN; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR; RETEPLASE; REVIPARIN; STAPHYLOKINASE; STREPTOKINASE; TINZAPARIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; UROKINASE;

EID: 0032586318     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008845822884     Document Type: Review
Times cited : (9)

References (129)
  • 1
    • 0030961921 scopus 로고    scopus 로고
    • Coronary risk factors and plaque morphology in men with coronary artery disease who die suddenly
    • Burke AP, Farb A, Malcom GT, Liang Y-H, Smialek J, Virmani R. Coronary risk factors and plaque morphology in men with coronary artery disease who die suddenly. N Eng J Med 1997;336:1276-1282.
    • (1997) N Eng J Med , vol.336 , pp. 1276-1282
    • Burke, A.P.1    Farb, A.2    Malcom, G.T.3    Liang, Y.-H.4    Smialek, J.5    Virmani, R.6
  • 2
    • 0028337135 scopus 로고
    • Dose finding with a novel recombinant plasminogen activator (BM 06.022) in patients with acute myocardial infarction: Results of the German Recombinant Plasminogen Activator Study
    • Neuhaus KL, von Essen R, Vogt A, et al. Dose finding with a novel recombinant plasminogen activator (BM 06.022) in patients with acute myocardial infarction: Results of the German Recombinant Plasminogen Activator Study. J Am Coll Cardiol 1994;24:55-60.
    • (1994) J am Coll Cardiol , vol.24 , pp. 55-60
    • Neuhaus, K.L.1    Von Essen, R.2    Vogt, A.3
  • 3
    • 0027203680 scopus 로고
    • Open, noncontrolled dose-finding study with a novel recombinant plasminogen activator (BM 06.022) given as a double bolus in patients with acute myocardial infarction
    • Tebbe U, von Essen R, Smolarz A, et al. Open, noncontrolled dose-finding study with a novel recombinant plasminogen activator (BM 06.022) given as a double bolus in patients with acute myocardial infarction. Am J Cardiol 1993;72:518-524.
    • (1993) Am J Cardiol , vol.72 , pp. 518-524
    • Tebbe, U.1    Von Essen, R.2    Smolarz, A.3
  • 4
    • 0029066701 scopus 로고
    • More rapid, complete, and stable coronary thrombolysis with bolus administration of reteplase compared with alteplase infusion in acute myocardial infarction
    • Smalling RW, Bode C, Kalbfleisch J, et al. and the RAPID Investigators. More rapid, complete, and stable coronary thrombolysis with bolus administration of reteplase compared with alteplase infusion in acute myocardial infarction. Circulation 1995;91:2725-2732.
    • (1995) Circulation , vol.91 , pp. 2725-2732
    • Smalling, R.W.1    Bode, C.2    Kalbfleisch, J.3
  • 5
    • 0343849937 scopus 로고    scopus 로고
    • Randomized comparison of coronary thrombolysis achieved with double bolus reteplase (r-PA) and front-loaded "accelerated" alteplase (rt-PA) in patients with acute myocardial infarction
    • Bode C, Smalling RW, Berg G, et al. and the RAPID Investigators. Randomized comparison of coronary thrombolysis achieved with double bolus reteplase (r-PA) and front-loaded "accelerated" alteplase (rt-PA) in patients with acute myocardial infarction. Circulation 1996;94:891-898.
    • (1996) Circulation , vol.94 , pp. 891-898
    • Bode, C.1    Smalling, R.W.2    Berg, G.3
  • 6
    • 0029142436 scopus 로고
    • Randomized, double-blind comparison of reteplase double-bolus administration with streptokinase in acute myocardial infarction (INJECT): Trial to investigate equivalence
    • INJECT Study Group. Randomized, double-blind comparison of reteplase double-bolus administration with streptokinase in acute myocardial infarction (INJECT): Trial to investigate equivalence. Lancet 1995;346:329-336.
    • (1995) Lancet , vol.346 , pp. 329-336
  • 7
    • 0030879325 scopus 로고    scopus 로고
    • A comparison of reteplase with a alteplase for acute myocardial infarction
    • The GUSTO III Investigators. A comparison of reteplase with a alteplase for acute myocardial infarction. N Engl J Med 1997;337:1118-1123.
    • (1997) N Engl J Med , vol.337 , pp. 1118-1123
  • 8
    • 0027297124 scopus 로고
    • A variant of tPA (T103N, KHRR-296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen
    • Refino CJ, Paoni NF, Keyt BA, et al. A variant of tPA (T103N, KHRR-296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen. Thromb Haemost 1993;70:313-319.
    • (1993) Thromb Haemost , vol.70 , pp. 313-319
    • Refino, C.J.1    Paoni, N.F.2    Keyt, B.A.3
  • 9
    • 16944362757 scopus 로고    scopus 로고
    • TNK-tissue plasminogen activator in acute myocardial infarction. Results of the Thrombolysis Infarction (TIMI) 10A dose-ranging trial
    • Cannon CP, McCabe CH, Gibson M, et al. and the TIMI 10A Investigators. TNK-tissue plasminogen activator in acute myocardial infarction. Results of the Thrombolysis Infarction (TIMI) 10A dose-ranging trial. Circulation 1997;95: 351-356.
    • (1997) Circulation , vol.95 , pp. 351-356
    • Cannon, C.P.1    McCabe, C.H.2    Gibson, M.3
  • 10
    • 0032578970 scopus 로고    scopus 로고
    • TNK-tPA compared with front-loaded Alteplase in Acute Myocardial Infarction: Results of the TIMI 10B Trial
    • Cannon CP, Gibson CM, McCabe CH, et al. for the TIMI 10b Investigators. TNK-tPA compared with front-loaded Alteplase in Acute Myocardial Infarction: Results of the TIMI 10B Trial. Circulation 1998;98:2805-2814.
    • (1998) Circulation , vol.98 , pp. 2805-2814
    • Cannon, C.P.1    Gibson, C.M.2    McCabe, C.H.3
  • 11
    • 0344919446 scopus 로고    scopus 로고
    • ASSENT I
    • ASSENT I
  • 12
    • 0032542048 scopus 로고    scopus 로고
    • Evaluation of a weight-adjusted single bolus plasminogen activator in patients with myocardial infarction. a Double-blind, randomized angiographic trial of Lanoteplase versus Alteplase
    • den Heijer P, Vermeer F, Ambrosioni E, et al. for the Im TIME investigators. Evaluation of a weight-adjusted single bolus plasminogen activator in patients with myocardial infarction. A Double-blind, randomized angiographic trial of Lanoteplase versus Alteplase. Circulation 1998;98: 2117-2125.
    • (1998) Circulation , vol.98 , pp. 2117-2125
    • Den Heijer, P.1    Vermeer, F.2    Ambrosioni, E.3
  • 13
    • 0025741431 scopus 로고
    • Comparative fibrinolytic properties of staphylokinase and streptokinase in animal models of venous thrombosis
    • Lijnen HR, Stassen JM, Vanlinthout I, et al. Comparative fibrinolytic properties of staphylokinase and streptokinase in animal models of venous thrombosis. Thromb Haemost 1991;66:468-473.
    • (1991) Thromb Haemost , vol.66 , pp. 468-473
    • Lijnen, H.R.1    Stassen, J.M.2    Vanlinthout, I.3
  • 14
    • 8944253299 scopus 로고    scopus 로고
    • Recombinant staphylokinase variants with altered immunoreactivity. I: Construction and characterization
    • Collen D, Bernaerts R, Declerck P, et al. Recombinant staphylokinase variants with altered immunoreactivity. I: Construction and characterization. Circulation 1996;94: 197-206.
    • (1996) Circulation , vol.94 , pp. 197-206
    • Collen, D.1    Bernaerts, R.2    Declerck, P.3
  • 15
    • 0028829271 scopus 로고
    • A randomized trial of recombinant staphylokinase versus alteplase for coronary artery patency in acute myocardial infarction
    • Vanderschueren S, Barrios L, Kerdsinchai P, et al. for the STAR Trial Group. A randomized trial of recombinant staphylokinase versus alteplase for coronary artery patency in acute myocardial infarction. Circulation 1995;92:2044-2049.
    • (1995) Circulation , vol.92 , pp. 2044-2049
    • Vanderschueren, S.1    Barrios, L.2    Kerdsinchai, P.3
  • 16
    • 0023878126 scopus 로고
    • Mutants of human tissue-plasminogen activator (tPA): Structural aspects and functional properties
    • Pannekoek H, de Vries C, Van Zonnerveld A-J. Mutants of human tissue-plasminogen activator (tPA): Structural aspects and functional properties. Fibrinolysis 1988;2: 123-1332.
    • (1988) Fibrinolysis , vol.2 , pp. 123-1332
    • Pannekoek, H.1    De Vries, C.2    Van Zonnerveld, A.-J.3
  • 17
    • 0001495165 scopus 로고
    • Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque
    • Wilcox JN, Smith KM, Schwartz SM, Gordon D. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 1989;86:2839-2843.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2839-2843
    • Wilcox, J.N.1    Smith, K.M.2    Schwartz, S.M.3    Gordon, D.4
  • 18
    • 0024386731 scopus 로고
    • Selective cellular expression of tissue factor in human tissues
    • Drake TA, Morrissey JH, Edgington TS. Selective cellular expression of tissue factor in human tissues. Am J Pathol 1989;134:1087-1097.
    • (1989) Am J Pathol , vol.134 , pp. 1087-1097
    • Drake, T.A.1    Morrissey, J.H.2    Edgington, T.S.3
  • 19
    • 0020548878 scopus 로고
    • Protection of factor Xa from neutralization by heparin-antithrombin complex
    • Teitel JM. Rosenberg RD. Protection of factor Xa from neutralization by heparin-antithrombin complex. J Clin Invest 1983;71:1383-1391.
    • (1983) J Clin Invest , vol.71 , pp. 1383-1391
    • Teitel, J.M.1    Rosenberg, R.D.2
  • 20
    • 0018198558 scopus 로고
    • Properties of the factor Xa binding site on platelets
    • Miletich JP, Jackson CM, Majerus PW. Properties of the factor Xa binding site on platelets. J Biol Chem 1978;253: 6908-6916.
    • (1978) J Biol Chem , vol.253 , pp. 6908-6916
    • Miletich, J.P.1    Jackson, C.M.2    Majerus, P.W.3
  • 21
    • 0022341051 scopus 로고
    • Efficacy and safety of low molecular weight heparin (CY216) in prevention postoperative venous thromboembolism: A co-operative study
    • Kakkar VV, Murray WJH. Efficacy and safety of low molecular weight heparin (CY216) in prevention postoperative venous thromboembolism: A co-operative study. Br J Surg 1985;72:786-791.
    • (1985) Br J Surg , vol.72 , pp. 786-791
    • Kakkar, V.V.1    Murray, W.J.H.2
  • 22
    • 0022965499 scopus 로고
    • Low molecular weight heparin (KABI-2165) as thromboprophylaxis in elective visceral surgery. a randomized double-blind study versus unfractionated heparin
    • Koller M, Schoch U, Buchmann P, Largiader F, Von Felten A, Frick PG. Low molecular weight heparin (KABI-2165) as thromboprophylaxis in elective visceral surgery. A randomized double-blind study versus unfractionated heparin. Thromb Haemost 1986;56:243-246.
    • (1986) Thromb Haemost , vol.56 , pp. 243-246
    • Koller, M.1    Schoch, U.2    Buchmann, P.3    Largiader, F.4    Von Felten, A.5    Frick, P.G.6
  • 23
    • 0021241666 scopus 로고
    • Clinical efficacy of low molecular weight heparin in postoperative thrombosis prophylaxis
    • Schmidt-Huebner U, Bunte H, Freise G, et al. Clinical efficacy of low molecular weight heparin in postoperative thrombosis prophylaxis. Klin Wochenschr 1984;62:349-353.
    • (1984) Klin Wochenschr , vol.62 , pp. 349-353
    • Schmidt-Huebner, U.1    Bunte, H.2    Freise, G.3
  • 24
    • 0023139761 scopus 로고
    • Early clinical experience of a new heparinoid, ORG 10172, in prevention of deep venous thrombosis
    • Cade JF, Wood M, Magnani HN, Westlake GW Early clinical experience of a new heparinoid, ORG 10172, in prevention of deep venous thrombosis. Thromb Res 1987;45:497-503.
    • (1987) Thromb Res , vol.45 , pp. 497-503
    • Cade, J.F.1    Wood, M.2    Magnani, H.N.3    Westlake, G.W.4
  • 25
    • 8044261304 scopus 로고    scopus 로고
    • Efficacy and safety of a low molecular weight heparin in prophylaxis of postoperative vein thrombosis after gynecologic surgery
    • Grunebaum L, Fricker JP, Wiesel ML, Vergnes Y, Cazenave JP, Barbier P, Kher A. Efficacy and safety of a low molecular weight heparin in prophylaxis of postoperative vein thrombosis after gynecologic surgery. Thromb Haemost 1987 (Suppl):420a.
    • Thromb Haemost , vol.1987 , Issue.SUPPL.
    • Grunebaum, L.1    Fricker, J.P.2    Wiesel, M.L.3    Vergnes, Y.4    Cazenave, J.P.5    Barbier, P.6    Kher, A.7
  • 26
    • 0344057099 scopus 로고
    • Low molecular weight heparin (fragmin) prophylaxis after gynecologic surgery
    • Briel RC, Hermann P, Hermann C, Doller P. Low molecular weight heparin (fragmin) prophylaxis after gynecologic surgery. Thromb Haemost 1987;1(Suppl.):424A.
    • (1987) Thromb Haemost , vol.1 , Issue.SUPPL.
    • Briel, R.C.1    Hermann, P.2    Hermann, C.3    Doller, P.4
  • 27
    • 2042536889 scopus 로고
    • Subcutaneous enoxaparin versus placebo for preventing deep vein thrombosis after transurethral prostatectomy
    • Le Gagneux F, Steg A, Le Guillov M. Subcutaneous enoxaparin versus placebo for preventing deep vein thrombosis after transurethral prostatectomy. Thromb Haemost 1987; 1(Suppl.) 413A.
    • (1987) Thromb Haemost , vol.1 , Issue.SUPPL.
    • Le Gagneux, F.1    Steg, A.2    Le Guillov, M.3
  • 28
    • 0023618805 scopus 로고
    • Randomized double-blind, placebo controlled safety study of low molecular weight heparinoid in patients undergoing transurethral resection of the prostate
    • ten Cate H, Henny CP, ten Cate JW, Buller HR, Dabhoiwala NF. Randomized double-blind, placebo controlled safety study of low molecular weight heparinoid in patients undergoing transurethral resection of the prostate. Thromb Haemost 1987;54:92-96.
    • (1987) Thromb Haemost , vol.54 , pp. 92-96
    • Ten Cate, H.1    Henny, C.P.2    Ten Cate, J.W.3    Buller, H.R.4    Dabhoiwala, N.F.5
  • 29
    • 0023837274 scopus 로고
    • Low molecular weight heparin compared with unfractionated heparin in prevention of postoperative thrombosis
    • Samama M, Bernard P, Bonnardot JP, Combe-Tamzali S, Lanson Y, Tissot E on behalf of the participants of the Groupe d'Etude de I'Enoxaparine (GENOX) multicentric trial. Low molecular weight heparin compared with unfractionated heparin in prevention of postoperative thrombosis. Br J Surg 1988;75:128-131.
    • (1988) Br J Surg , vol.75 , pp. 128-131
    • Samama, M.1    Bernard, P.2    Bonnardot, J.P.3    Combe-Tamzali, S.4    Lanson, Y.5    Tissot, E.6
  • 30
    • 0022531588 scopus 로고
    • A randomized controlled trial of a low molecular weight heparin (enoxaparine) to prevent deep vein thrombosis in patients undergoing elective hip surgery
    • Turpie AGG, Levine MN, Hirsh J, et al. A randomized controlled trial of a low molecular weight heparin (enoxaparine) to prevent deep vein thrombosis in patients undergoing elective hip surgery. N Engl J Med 1987;315:929-929.
    • (1987) N Engl J Med , vol.315 , pp. 929-929
    • Turpie, A.G.G.1    Levine, M.N.2    Hirsh, J.3
  • 31
    • 0008564344 scopus 로고
    • Enoxaparin (Lovenox®), versus standard heparin in prophylaxis of deep vein thrombosis after total hip replacement
    • Le Balc'h, Landais A, Butel, Weill D, Pascariello JC, Planes A. Enoxaparin (Lovenox®), versus standard heparin in prophylaxis of deep vein thrombosis after total hip replacement. Thromb Haemost 1987;1(Suppl.):892A.
    • (1987) Thromb Haemost , vol.1 , Issue.SUPPL.
    • Le Balc'h1    Landais, A.2    Butel3    Weill, D.4    Pascariello, J.C.5    Planes, A.6
  • 32
    • 0008735660 scopus 로고
    • Thrombosis prophylaxis with low molecular weight heparin (KABI 2165) and calcium heparin in patients with total hip replacement
    • Potron G, Barre J, Droulle C, Baudyillard JC, Barbier P, Kher A. Thrombosis prophylaxis with low molecular weight heparin (KABI 2165) and calcium heparin in patients with total hip replacement. Thromb Haemost 1987;1(Suppl.): 421A.
    • (1987) Thromb Haemost , vol.1 , Issue.SUPPL.
    • Potron, G.1    Barre, J.2    Droulle, C.3    Baudyillard, J.C.4    Barbier, P.5    Kher, A.6
  • 33
    • 0344057098 scopus 로고
    • Prevention of deep vein thrombosis after total hip replacement by enoxaparine: One daily injection of 40 mg versus two daily injections of 20 mg
    • Planes A, V Vochelle, C Mansat. Prevention of deep vein thrombosis after total hip replacement by enoxaparine: One daily injection of 40 mg versus two daily injections of 20 mg. Thromb Haemost 1987;1(Suppl.)415A.
    • (1987) Thromb Haemost , vol.1 , Issue.SUPPL.
    • Planes, A.1    Vochelle, V.2    Mansat, C.3
  • 35
    • 4244184468 scopus 로고
    • Prevention of deep vein thrombosis by enoxaparine after surgery for fracture of femoral neck. Once daily injection of 40 mg versus two daily injection of 20 mg
    • Barsotti J, Dabo B, Andrew J, Alison D, Leroy J, Delahousse B. Prevention of deep vein thrombosis by enoxaparine after surgery for fracture of femoral neck. Once daily injection of 40 mg versus two daily injection of 20 mg. Thromb Haemost 1987;1(Suppl.):891A.
    • (1987) Thromb Haemost , vol.1 , Issue.SUPPL.
    • Barsotti, J.1    Dabo, B.2    Andrew, J.3    Alison, D.4    Leroy, J.5    Delahousse, B.6
  • 36
    • 0022471241 scopus 로고
    • Enoxaparine low molecular weight heparin: Its use in the prevention of deep venous thrombosis following total hip replacement
    • Planes A, Vochelle N, Ferru J, Przyrowski D, Clerc J, Fagola M, Planes M. Enoxaparine low molecular weight heparin: Its use in the prevention of deep venous thrombosis following total hip replacement. Haemostasis 1986;16:152-158.
    • (1986) Haemostasis , vol.16 , pp. 152-158
    • Planes, A.1    Vochelle, N.2    Ferru, J.3    Przyrowski, D.4    Clerc, J.5    Fagola, M.6    Planes, M.7
  • 37
    • 0022512750 scopus 로고
    • Prevention of deep thrombosis in elderly medical inpatients by a low molecular heparin: A randomized double-blind trial
    • Dahan R, Houlbert D, Caulin C, et al. Prevention of deep thrombosis in elderly medical inpatients by a low molecular heparin: A randomized double-blind trial. Haemostasis 1986;16:159-164.
    • (1986) Haemostasis , vol.16 , pp. 159-164
    • Dahan, R.1    Houlbert, D.2    Caulin, C.3
  • 39
    • 0023138247 scopus 로고
    • Double-blind randomized trial of ORG 10172 low-molecular-weight heparinoid in prevention of deep-vein thrombosis in thrombotic stroke
    • Turpie AGG, Hirsh J, Jay RM, et al. Double-blind randomized trial of ORG 10172 low-molecular-weight heparinoid in prevention of deep-vein thrombosis in thrombotic stroke. Lancet 1987;11:523-526.
    • (1987) Lancet , vol.11 , pp. 523-526
    • Turpie, A.G.G.1    Hirsh, J.2    Jay, R.M.3
  • 40
    • 0025064869 scopus 로고
    • Prevention of thromboembolism after spinal cord injury using low-molecular-weight heparin
    • Green D, Lee MY, Lim AC, et al. Prevention of thromboembolism after spinal cord injury using low-molecular-weight heparin. Ann Intern Med 1990;113:571-574.
    • (1990) Ann Intern Med , vol.113 , pp. 571-574
    • Green, D.1    Lee, M.Y.2    Lim, A.C.3
  • 41
    • 0025254642 scopus 로고
    • A double-blind and randomized placebo controlled trial of low molecular weight heparin once daily to prevent deep vein thrombosis in acute ischemic stroke
    • Sandset PM, Dahl T, Stiris M, Rostad B, Scheel B, Abildgaard U. A double-blind and randomized placebo controlled trial of low molecular weight heparin once daily to prevent deep vein thrombosis in acute ischemic stroke. Semin Thromb Hemost 1990;16(Suppl.):25-33.
    • (1990) Semin Thromb Hemost , vol.16 , Issue.SUPPL. , pp. 25-33
    • Sandset, P.M.1    Dahl, T.2    Stiris, M.3    Rostad, B.4    Scheel, B.5    Abildgaard, U.6
  • 43
    • 0026737897 scopus 로고
    • A low-molecular-weight heparinoid compared with unfractionated heparin in the prevention of deep vein thrombosis in patients with acute ischemic stroke. a randomized, double-blind study
    • Turpie AGG, Gent M, Côte R, et al. A low-molecular-weight heparinoid compared with unfractionated heparin in the prevention of deep vein thrombosis in patients with acute ischemic stroke. A randomized, double-blind study. Ann Intern Med 1992;117:353-357.
    • (1992) Ann Intern Med , vol.117 , pp. 353-357
    • Turpie, A.G.G.1    Gent, M.2    Côte, R.3
  • 44
    • 0025151664 scopus 로고
    • Randomized controlled study of heparin in low molecular Weight heparin for prevention of deep-vein thrombosis in medical patients
    • Harenberg J, Kallenbach B, Martin U, Dempfle CE, Zimmermann R, Kübler W, Heene DL. Randomized controlled study of heparin in low molecular Weight heparin for prevention of deep-vein thrombosis in medical patients. Thromb Res 1990;59:639-650.
    • (1990) Thromb Res , vol.59 , pp. 639-650
    • Harenberg, J.1    Kallenbach, B.2    Martin, U.3    Dempfle, C.E.4    Zimmermann, R.5    Kübler, W.6    Heene, D.L.7
  • 45
    • 0025693253 scopus 로고    scopus 로고
    • Deep venous thrombosis and left ventricular thrombosis prophylaxis by low molecular weight heparin in acute myocardial infarction
    • 199
    • Scala P-J, Thiollet M, Midavaine M, et al. Deep venous thrombosis and left ventricular thrombosis prophylaxis by low molecular weight heparin in acute myocardial infarction. Haemostasis 199?;20:368-369.
    • Haemostasis , vol.20 , pp. 368-369
    • Scala, P.-J.1    Thiollet, M.2    Midavaine, M.3
  • 46
    • 0026329221 scopus 로고
    • Safety of high doses of low molecular weight heparin (Fragmin) in acute myocardial infarction. a dose-finding study
    • Nesvold A, Kontny F, Abildgaard U, Dale J. Safety of high doses of low molecular weight heparin (Fragmin) in acute myocardial infarction. A dose-finding study. Thromb Res 1991;64:579-587.
    • (1991) Thromb Res , vol.64 , pp. 579-587
    • Nesvold, A.1    Kontny, F.2    Abildgaard, U.3    Dale, J.4
  • 47
    • 0022345880 scopus 로고
    • A comparison between low molecular weight heparin (KABI 2165) and standard heparin in the intravenous treatment of deep venous thrombosis
    • Bratt G. Törnebohm E, Granquist S, Aberg W, Lockner D. A comparison between low molecular weight heparin (KABI 2165) and standard heparin in the intravenous treatment of deep venous thrombosis. Thromb Haemost 1985;54:813-817.
    • (1985) Thromb Haemost , vol.54 , pp. 813-817
    • Bratt, G.1    Törnebohm, E.2    Granquist, S.3    Aberg, W.4    Lockner, D.5
  • 48
    • 0026576068 scopus 로고
    • Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximal-vein thrombosis
    • Hull RD, Raskob GE, Pineo GF, et al. Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximal-vein thrombosis. N Engl J Med 1992;236:975-982.
    • (1992) N Engl J Med , vol.236 , pp. 975-982
    • Hull, R.D.1    Raskob, G.E.2    Pineo, G.F.3
  • 49
    • 0005640680 scopus 로고
    • Efficacy and safety of a low molecular weight heparin (LMW-heparin Sandoz) in patients with deep vein thrombosis
    • Vogel G, Machulik M. Efficacy and safety of a low molecular weight heparin (LMW-heparin Sandoz) in patients with deep vein thrombosis. Thromb Haemost 1987;59:120.
    • (1987) Thromb Haemost , vol.59 , pp. 120
    • Vogel, G.1    Machulik, M.2
  • 50
    • 0024438351 scopus 로고
    • Treatment of venous thromboembolism with low molecular weight heparin (Fragmin)
    • Albada J, Nieuwenhuis HK, Sixma JJ. Treatment of venous thromboembolism with low molecular weight heparin (Fragmin). Circulation 1989;80:935-940.
    • (1989) Circulation , vol.80 , pp. 935-940
    • Albada, J.1    Nieuwenhuis, H.K.2    Sixma, J.J.3
  • 51
    • 0025690181 scopus 로고
    • Two daily subcutaneous injections of Fragmin as compared with intravenous standard heparin in the treatment of deep venous thrombosis (DVT)
    • Bratt G, Aberg W, Johannsson M, Törnebohm E, Granquist S, Lockner D. Two daily subcutaneous injections of Fragmin as compared with intravenous standard heparin in the treatment of deep venous thrombosis (DVT). Thromb Haemost 1991;64:506-510.
    • (1991) Thromb Haemost , vol.64 , pp. 506-510
    • Bratt, G.1    Aberg, W.2    Johannsson, M.3    Törnebohm, E.4    Granquist, S.5    Lockner, D.6
  • 52
    • 0025678942 scopus 로고
    • Therapeutic application of subcutaneous low-molecular-weight heparin in acute venous thrombosis
    • Harenberg J, Huck K, Bratsch H, et al. Therapeutic application of subcutaneous low-molecular-weight heparin in acute venous thrombosis. Haemostasis 1990;20:205-219.
    • (1990) Haemostasis , vol.20 , pp. 205-219
    • Harenberg, J.1    Huck, K.2    Bratsch, H.3
  • 53
    • 0025805462 scopus 로고
    • A randomized trial of subcutaneous low molecular weight heparin (CY 216) compared with intravenous unfractionated heparin in the treatment of deep vein thrombosis. a collaborative European multicentre study
    • Duroux P. A randomized trial of subcutaneous low molecular weight heparin (CY 216) compared with intravenous unfractionated heparin in the treatment of deep vein thrombosis. A collaborative European multicentre study. Thromb Haemost 1991;65:251-256.
    • (1991) Thromb Haemost , vol.65 , pp. 251-256
    • Duroux, P.1
  • 54
    • 0026569416 scopus 로고
    • Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis
    • Prandoni P, Lensing AWA, B Büller HR, et al. Comparison of subcutaneous low-molecular-weight heparin with intravenous standard heparin in proximal deep-vein thrombosis. Lancelet 1992;339:441-445.
    • (1992) Lancelet , vol.339 , pp. 441-445
    • Prandoni, P.1    Lensing, A.W.A.2    Büller, H.R.3
  • 55
    • 0022485055 scopus 로고
    • Subcutaneous heparin treatment of deep venous thrombosis: A comparison of unfractionated with low molecular weight heparin
    • Holm HA, Ly B, Handeland GF, et al. Subcutaneous heparin treatment of deep venous thrombosis: A comparison of unfractionated with low molecular weight heparin. Haemostasis 1986;16:30-37.
    • (1986) Haemostasis , vol.16 , pp. 30-37
    • Holm, H.A.1    Ly, B.2    Handeland, G.F.3
  • 56
    • 0026653943 scopus 로고
    • Subcutaneous low molecular weight heparin versus subcutaneous unfractionated heparin in the treatment of deep vein thrombosis: A Polish multicenter trial
    • Lopaciuk S, Meissner AJ, Filipecki S, et al. Subcutaneous low molecular weight heparin versus subcutaneous unfractionated heparin in the treatment of deep vein thrombosis: A Polish multicenter trial. Thromb Haemost 1992;68:14-18.
    • (1992) Thromb Haemost , vol.68 , pp. 14-18
    • Lopaciuk, S.1    Meissner, A.J.2    Filipecki, S.3
  • 58
    • 0026539557 scopus 로고
    • Randomized trial of subcutaneous low-molecular-weight heparin CY 216 (Fraxiparin) compared with intravenous unfractionated heparin in the curative treatment of submassive pulmonary embolism. a dose-ranging study
    • Théry C, Simonneau G, Meyer G, et al. Randomized trial of subcutaneous low-molecular-weight heparin CY 216 (Fraxiparin) compared with intravenous unfractionated heparin in the curative treatment of submassive pulmonary embolism. A dose-ranging study. Circulation 1992;85:1380-1389.
    • (1992) Circulation , vol.85 , pp. 1380-1389
    • Théry, C.1    Simonneau, G.2    Meyer, G.3
  • 59
    • 0344919442 scopus 로고
    • Fragmin (Kabi) subcutaneously once or twice daily in the treatment of deep venous thrombosis (DVT)
    • Lockner D, Johansson M, Aberg W, Bratt G, Granquist S. Fragmin (Kabi) subcutaneously once or twice daily in the treatment of deep venous thrombosis (DVT). Thromb Haemost 1989;62:526.
    • (1989) Thromb Haemost , vol.62 , pp. 526
    • Lockner, D.1    Johansson, M.2    Aberg, W.3    Bratt, G.4    Granquist, S.5
  • 60
    • 0025805462 scopus 로고
    • A randomized trial of subcutaneous low molecular weight heparin (CY 216) compared with intravenous unfractionated heparin in the treatment of deep vein thrombosis
    • A Collaborative European Multicentre Study. A randomized trial of subcutaneous low molecular weight heparin (CY 216) compared with intravenous unfractionated heparin in the treatment of deep vein thrombosis. Thromb Haemost 1991; 65:251-256.
    • (1991) Thromb Haemost , vol.65 , pp. 251-256
  • 61
    • 0027254958 scopus 로고
    • Subcutaneous low-molecular-weight heparin compared with continuous intravenous unfractionated heparin in the treatment of proximal deep vein thrombosis
    • Simonneau G, Charbonnier B, Decousus H, et al. Subcutaneous low-molecular-weight heparin compared with continuous intravenous unfractionated heparin in the treatment of proximal deep vein thrombosis. Arch Intern Med 1993;153: 1541-1546.
    • (1993) Arch Intern Med , vol.153 , pp. 1541-1546
    • Simonneau, G.1    Charbonnier, B.2    Decousus, H.3
  • 62
    • 0028939906 scopus 로고
    • Treatment of deep venous thrombosis with low-molecular-weight heparins
    • Lensing AWA, Prins MH, Davidson BL, Hirsh J. Treatment of deep venous thrombosis with low-molecular-weight heparins. Arch Intern Med 1995;155:601-607.
    • (1995) Arch Intern Med , vol.155 , pp. 601-607
    • Lensing, A.W.A.1    Prins, M.H.2    Davidson, B.L.3    Hirsh, J.4
  • 63
    • 0023495494 scopus 로고
    • Anticoagulation in hemodialysis sessions with a low molecular weight heparin (CY 222)
    • Dieval J, Moriniére P, Roussel B, Bayrou B, Fournier A, Delobel J. Anticoagulation in hemodialysis sessions with a low molecular weight heparin (CY 222). J Mal Vasc 1987; 12:114-118.
    • (1987) J Mal Vasc , vol.12 , pp. 114-118
    • Dieval, J.1    Moriniére, P.2    Roussel, B.3    Bayrou, B.4    Fournier, A.5    Delobel, J.6
  • 64
    • 0022456678 scopus 로고
    • Partial reversal of low molecular weight heparin (PK 10169) and anti-Xa activity by protamine sulfate
    • Massonnet-Castel S, Pelissier E, Bara L, et al. Partial reversal of low molecular weight heparin (PK 10169) and anti-Xa activity by protamine sulfate. Haemostasis 1986;16:139-146.
    • (1986) Haemostasis , vol.16 , pp. 139-146
    • Massonnet-Castel, S.1    Pelissier, E.2    Bara, L.3
  • 65
    • 0028039182 scopus 로고
    • The effect of subcutaneous injection of unfractionated and low molecular weight heparin on thrombin generation in platelet rich plasma - A study in human volunteers
    • Bendetowicz AV, Kai H, Knebel R, Caplain H, Hemker HC, Lindhout T, Béguin S. The effect of subcutaneous injection of unfractionated and low molecular weight heparin on thrombin generation in platelet rich plasma - A study in human volunteers. Thromb Haemost 1994;72:705-712.
    • (1994) Thromb Haemost , vol.72 , pp. 705-712
    • Bendetowicz, A.V.1    Kai, H.2    Knebel, R.3    Caplain, H.4    Hemker, H.C.5    Lindhout, T.6    Béguin, S.7
  • 66
    • 0027213684 scopus 로고
    • Comparison of the efficacy of low molecular weight heparin (parnaparin) with that of unfractionated heparin in the presence of activated platelets in healthy subjects
    • Melandri G, Semprini F, Cervi V, Candiotti N, Branzi A, Palazzini E, Magnani B. Comparison of the efficacy of low molecular weight heparin (parnaparin) with that of unfractionated heparin in the presence of activated platelets in healthy subjects. Am J Cardiol 1993;72:450-454.
    • (1993) Am J Cardiol , vol.72 , pp. 450-454
    • Melandri, G.1    Semprini, F.2    Cervi, V.3    Candiotti, N.4    Branzi, A.5    Palazzini, E.6    Magnani, B.7
  • 67
    • 0028966404 scopus 로고
    • Reversal of heparin anticoagulation by recombinant platelet factor 4 in humans
    • Dehmer GJ, Fisher M, Tate DA, Teo S, Bonnem EM. Reversal of heparin anticoagulation by recombinant platelet factor 4 in humans. Circulation 1995;91:2188-2194.
    • (1995) Circulation , vol.91 , pp. 2188-2194
    • Dehmer, G.J.1    Fisher, M.2    Tate, D.A.3    Teo, S.4    Bonnem, E.M.5
  • 69
    • 0028211342 scopus 로고
    • Ex vivo and in vitro evidence that low molecular weight heparin exhibits less binding to plasma proteins that unfractionated heparin
    • Young E, Walls P, Holloway S, Weitz J, Ex vivo and in vitro evidence that low molecular weight heparin exhibits less binding to plasma proteins that unfractionated heparin. Thromb Haemost 1994;71:300-304.
    • (1994) Thromb Haemost , vol.71 , pp. 300-304
    • Young, E.1    Walls, P.2    Holloway, S.3    Weitz, J.4
  • 70
    • 0029100793 scopus 로고
    • Low molecular weight heparin versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia
    • Gurfinkel EP, Manos EJ, Mejail RI, et al. Low molecular weight heparin versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia. J Am Coll Cardiol 1995;26:313-318.
    • (1995) J am Coll Cardiol , vol.26 , pp. 313-318
    • Gurfinkel, E.P.1    Manos, E.J.2    Mejail, R.I.3
  • 71
    • 9044243412 scopus 로고    scopus 로고
    • Low molecular weight heparin during unstability in coronary artery disease
    • The FRISC Study Group. Low molecular weight heparin during unstability in coronary artery disease. Lancet 1996 ;347:561-568.
    • (1996) Lancet , vol.347 , pp. 561-568
  • 72
    • 0030789174 scopus 로고    scopus 로고
    • Comparison of low molecular weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease. Fragmin in Unstable Coronary Artery Disease Study (FRIC)
    • Klein W, Buchwald A, Hilli SE, et al. Comparison of low molecular weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease. Fragmin in Unstable Coronary Artery Disease Study (FRIC). Circulation 1997;96:61-68.
    • (1997) Circulation , vol.96 , pp. 61-68
    • Klein, W.1    Buchwald, A.2    Hilli, S.E.3
  • 73
    • 8544279582 scopus 로고    scopus 로고
    • A comparison of low-molecular weight heparin with unfractionated heparin for unstable coronary artery disease
    • Cohen M, Demers C, Gurfinkel EP for the ESSENCE Investigators. A comparison of low-molecular weight heparin with unfractionated heparin for unstable coronary artery disease. N Engl J Med 1997;337:447-452.
    • (1997) N Engl J Med , vol.337 , pp. 447-452
    • Cohen, M.1    Demers, C.2    Gurfinkel, E.P.3
  • 74
    • 0344488291 scopus 로고
    • Absence of bleeding and subacute occlusion after Palmaz-Schatz coronary stenting using a new antithrombotic regimen
    • Fernandez-Aviles F, Alonso J, Duran JM, et al. Absence of bleeding and subacute occlusion after Palmaz-Schatz coronary stenting using a new antithrombotic regimen. J Am Coll Cardiol 1995;1(Suppl. A):196A.
    • (1995) J am Coll Cardiol , vol.1 , Issue.SUPPL. A
    • Fernandez-Aviles, F.1    Alonso, J.2    Duran, J.M.3
  • 76
    • 0344057093 scopus 로고    scopus 로고
    • Low molecular weight heparin and elective stenting: The ENTICES Trial
    • Orlando, FL, November 9-13
    • Zidar JP, Kruse KR, Berkowitz SD, et al. Low molecular weight heparin and elective stenting: The ENTICES Trial. Presented at the American Heart Association Meetings, Orlando, FL, November 9-13, 1997.
    • (1997) American Heart Association Meetings
    • Zidar, J.P.1    Kruse, K.R.2    Berkowitz, S.D.3
  • 77
    • 0344919438 scopus 로고    scopus 로고
    • Low molecular weight heparin after acute MI can prevent recurrence of acute cardiac events after thrombolytic treatment
    • Orlando, FL, November 9-13
    • Glick A, Laniado S, Keren G. Low molecular weight heparin after acute MI can prevent recurrence of acute cardiac events after thrombolytic treatment. Presented at the American Heart Association Meetings, Orlando, FL, November 9-13, 1997.
    • (1997) American Heart Association Meetings
    • Glick, A.1    Laniado, S.2    Keren, G.3
  • 78
    • 0344057091 scopus 로고    scopus 로고
    • Enoxaparin versus unfractionated heparin after thrombolysis for acute myocardial infarction
    • Orlando, FL, November 9-13
    • Wilson C, Baird S, Trouton T. Enoxaparin versus unfractionated heparin after thrombolysis for acute myocardial infarction. Presented at the American Heart Association Meetings, Orlando, FL, November 9-13, 1997.
    • (1997) American Heart Association Meetings
    • Wilson, C.1    Baird, S.2    Trouton, T.3
  • 79
    • 0028236050 scopus 로고
    • Adjusted versus fixed doses of the low molecular weight heparin fragmin in the treatment of deep venous thrombosis
    • Alhenc-Gelas M, Jestin-Le Guernic C, Vitoux JF, et al. Adjusted versus fixed doses of the low molecular weight heparin fragmin in the treatment of deep venous thrombosis. Thromb Haemost 1994;71:698-702.
    • (1994) Thromb Haemost , vol.71 , pp. 698-702
    • Alhenc-Gelas, M.1    Jestin-Le Guernic, C.2    Vitoux, J.F.3
  • 80
    • 0022005992 scopus 로고
    • Comparative pharmacokinetics of a low molecular weight heparin (PK 10169) and unfractionated heparin after intravenous and subcutaneous administration
    • Bara L, Billaud E, Gramond G, Kher A, Samama M. Comparative pharmacokinetics of a low molecular weight heparin (PK 10169) and unfractionated heparin after intravenous and subcutaneous administration. Thromb Res 1985;39:631-636.
    • (1985) Thromb Res , vol.39 , pp. 631-636
    • Bara, L.1    Billaud, E.2    Gramond, G.3    Kher, A.4    Samama, M.5
  • 81
    • 0025160385 scopus 로고
    • Dose adjusted heparin treatment of deep venous thrombosis: A comparison of unfractionated and low molecular weight heparin
    • Handeland GF, Abildgaard U, Holm HA, Arnesen KE. Dose adjusted heparin treatment of deep venous thrombosis: A comparison of unfractionated and low molecular weight heparin. Eur J Clin Pharmacol 1990;39:107-112.
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 107-112
    • Handeland, G.F.1    Abildgaard, U.2    Holm, H.A.3    Arnesen, K.E.4
  • 82
    • 85088280528 scopus 로고
    • A comparison between low molecular weight heparin (Kabi 2165) and standard heparin in the intravenous treatment of deep venous thrombosis
    • Bratt G, Tornebohm E, Grnaqvist S, Aberq W, Lockner D. A comparison between low molecular weight heparin (Kabi 2165) and standard heparin in the intravenous treatment of deep venous thrombosis. Thromb Haemost 1989;59:813-817.
    • (1989) Thromb Haemost , vol.59 , pp. 813-817
    • Bratt, G.1    Tornebohm, E.2    Grnaqvist, S.3    Aberq, W.4    Lockner, D.5
  • 83
    • 0025082456 scopus 로고
    • Bleeding times in rats treated with heparin, heparin fragments of high and low anticoagulant activity and chemically modified heparin fragments of low anticoagulant activity
    • Palm M, Mattsson C, Magnus Svahn C, Weber M. Bleeding times in rats treated with heparin, heparin fragments of high and low anticoagulant activity and chemically modified heparin fragments of low anticoagulant activity. Thromb Haemost 1990; 64:127-132.
    • (1990) Thromb Haemost , vol.64 , pp. 127-132
    • Palm, M.1    Mattsson, C.2    Magnus Svahn, C.3    Weber, M.4
  • 84
    • 0019986915 scopus 로고
    • The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits
    • Carter CJ, Kelton JG, Hirsh J, Cerskus A, Santos AV, Gent M. The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits. Blood 1982;59:1239-1245.
    • (1982) Blood , vol.59 , pp. 1239-1245
    • Carter, C.J.1    Kelton, J.G.2    Hirsh, J.3    Cerskus, A.4    Santos, A.V.5    Gent, M.6
  • 85
    • 0027977890 scopus 로고
    • Pharmacological properties of CY 216 and of its ACLM and BCLM components in the rabbit
    • Peyrou V, Lormeau JC, Caranobe C, et al. Pharmacological properties of CY 216 and of its ACLM and BCLM components in the rabbit. Thromb Haemost 1994;72:268-274.
    • (1994) Thromb Haemost , vol.72 , pp. 268-274
    • Peyrou, V.1    Lormeau, J.C.2    Caranobe, C.3
  • 86
    • 0022965499 scopus 로고
    • Low molecular weight heparin (Kabi 2165) as thromboprophylaxis in elective visceral surgery. a randomized, double-blind study versus unfractionated heparin
    • Koller M, Schoch U, Buchmann P, Largiader F, Fon Felten A, Frieck PG. Low molecular weight heparin (Kabi 2165) as thromboprophylaxis in elective visceral surgery. A randomized, double-blind study versus unfractionated heparin. Thromb Haemost 1986;56:243-246.
    • (1986) Thromb Haemost , vol.56 , pp. 243-246
    • Koller, M.1    Schoch, U.2    Buchmann, P.3    Largiader, F.4    Fon Felten, A.5    Frieck, P.G.6
  • 87
    • 0022510522 scopus 로고
    • Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily. Aprospective double-blind multicentre trial on prevention of postoperative thrombosis
    • Bergqvist D, Burmark US, Frisell J, Lindblad B, Risberg B, Torngren S, Walling G. Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily. Aprospective double-blind multicentre trial on prevention of postoperative thrombosis. Br J Surg 1986;73:204-208.
    • (1986) Br J Surg , vol.73 , pp. 204-208
    • Bergqvist, D.1    Burmark, U.S.2    Frisell, J.3    Lindblad, B.4    Risberg, B.5    Torngren, S.6    Walling, G.7
  • 88
    • 0023837274 scopus 로고
    • Low molecular weight heparin compared with unfractionated heparin in prevention of post operative thrombosis
    • Samama M, Bernard P, Bonnardot JP, Combe-Tamzali S, Lanson Y, Tissot E. Low molecular weight heparin compared with unfractionated heparin in prevention of post operative thrombosis. Br J Surg 1988;75:128-131.
    • (1988) Br J Surg , vol.75 , pp. 128-131
    • Samama, M.1    Bernard, P.2    Bonnardot, J.P.3    Combe-Tamzali, S.4    Lanson, Y.5    Tissot, E.6
  • 89
    • 0025996472 scopus 로고
    • Identification of risk factors for bleeding during treatment of acute venous thromboembolism with heparin or low molecular weight heparin
    • Nieuwenhauis K, Albada J, Banga JD, Sixma JJ. Identification of risk factors for bleeding during treatment of acute venous thromboembolism with heparin or low molecular weight heparin. Blood 1991;78:2337-2343.
    • (1991) Blood , vol.78 , pp. 2337-2343
    • Nieuwenhauis, K.1    Albada, J.2    Banga, J.D.3    Sixma, J.J.4
  • 90
    • 0022510522 scopus 로고
    • Efficacy and cost of low-molecular-weight heparin compared with standard multicenter trial on prevention of postoperative thrombosis
    • Anderson DR, O'Brien BJ, Levine MN, Roberts R, Wells PS, Hirsh J. Efficacy and cost of low-molecular-weight heparin compared with standard multicenter trial on prevention of postoperative thrombosis. Br J Surg 1986;73:204-208.
    • (1986) Br J Surg , vol.73 , pp. 204-208
    • Anderson, D.R.1    O'Brien, B.J.2    Levine, M.N.3    Roberts, R.4    Wells, P.S.5    Hirsh, J.6
  • 91
    • 0025786839 scopus 로고
    • The determination of the levels of unfractionated heparin and low molecular weight heparins in plasma: Their effect on thrombin mediated feedback reactions in vivo. Preliminary results after subcutaneous injection
    • Hemker H, Béguin S, Bendetowicz A, Wielders S. The determination of the levels of unfractionated heparin and low molecular weight heparins in plasma: Their effect on thrombin mediated feedback reactions in vivo. Preliminary results after subcutaneous injection. Haemostasis 1991;21:258-272.
    • (1991) Haemostasis , vol.21 , pp. 258-272
    • Hemker, H.1    Béguin, S.2    Bendetowicz, A.3    Wielders, S.4
  • 92
    • 0020362545 scopus 로고
    • Kinetics of intravenously administered heparin in normal humans
    • De Swart CAM, Nijmeyer B, Roelofs JMM, Sixma JJ. Kinetics of intravenously administered heparin in normal humans. Blood 1982;60:1251-1258.
    • (1982) Blood , vol.60 , pp. 1251-1258
    • De Swart, C.A.M.1    Nijmeyer, B.2    Roelofs, J.M.M.3    Sixma, J.J.4
  • 93
    • 0030992622 scopus 로고    scopus 로고
    • Dose ranging trial of enoxaparin for unstable angina: Results of TIMI 11A
    • The TIMI 11A Investigators. Dose ranging trial of enoxaparin for unstable angina: Results of TIMI 11A. J Am Coll Cardiol 1997;29:1474-1482.
    • (1997) J am Coll Cardiol , vol.29 , pp. 1474-1482
  • 94
    • 0029092536 scopus 로고
    • The effects of low molecular weight heparin and standard heparin on calcium loss from fetal rat calvaria
    • Shaughnessy SG, Young E, Deschamps P, Hirsh J. The effects of low molecular weight heparin and standard heparin on calcium loss from fetal rat calvaria. Blood 1995;86: 1368-1373.
    • (1995) Blood , vol.86 , pp. 1368-1373
    • Shaughnessy, S.G.1    Young, E.2    Deschamps, P.3    Hirsh, J.4
  • 95
    • 0024414476 scopus 로고
    • Comparative antithrombotic and hemorrhagic effects of dermatan sulfate, heparan sulfate, and heparin
    • Hoppenstead D, Racanelli A, Walenga JM, Fareed J. Comparative antithrombotic and hemorrhagic effects of dermatan sulfate, heparan sulfate, and heparin. Sem Thromb Hemost 1989;15:378-385.
    • (1989) Sem Thromb Hemost , vol.15 , pp. 378-385
    • Hoppenstead, D.1    Racanelli, A.2    Walenga, J.M.3    Fareed, J.4
  • 96
    • 9044240864 scopus 로고    scopus 로고
    • Low-molecular-weight heparinoid Orgaran is more effective than aspirin in the prevention of venous thromboembolism after surgery for hip fracture
    • Gent M, Hirsh J, Ginsberg JS, et al. Low-molecular-weight heparinoid Orgaran is more effective than aspirin in the prevention of venous thromboembolism after surgery for hip fracture. Circulation 1996;93:80-84.
    • (1996) Circulation , vol.93 , pp. 80-84
    • Gent, M.1    Hirsh, J.2    Ginsberg, J.S.3
  • 97
    • 0029034399 scopus 로고
    • Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism. a randomized controlled trial
    • de Valk HW, Banga JD, Wester JWJ, et al. Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism. A randomized controlled trial. Ann Intern Med 1995;123:1-9.
    • (1995) Ann Intern Med , vol.123 , pp. 1-9
    • De Valk, H.W.1    Banga, J.D.2    Jwj, W.3
  • 98
    • 0027442550 scopus 로고
    • Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with orgaran (Org 10172)
    • Magnani HN. Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with orgaran (Org 10172). Thromb Haemost 1993;70:554-561.
    • (1993) Thromb Haemost , vol.70 , pp. 554-561
    • Magnani, H.N.1
  • 99
    • 0023666065 scopus 로고
    • Integrins: A family of cell surface receptors
    • Hynes Ro. Integrins: A family of cell surface receptors. Cell 1987;48:549-54.
    • (1987) Cell , vol.48 , pp. 549-554
    • Hynes, Ro.1
  • 100
    • 0024531099 scopus 로고
    • Cellular adhesion:GPIIb/IIIa as a prototypic adhesion receptor
    • Plow EF, Ginsberg MH. Cellular adhesion:GPIIb/IIIa as a prototypic adhesion receptor. Prog Hemostas Thromb 1989; 9:117-56.
    • (1989) Prog Hemostas Thromb , vol.9 , pp. 117-156
    • Plow, E.F.1    Ginsberg, M.H.2
  • 101
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 102
    • 0025205276 scopus 로고
    • Integrins and other cell adhesion molecules
    • Albeda SM, Buck CA. Integrins and other cell adhesion molecules. FASEB J 1990;4:2868-2880.
    • (1990) FASEB J , vol.4 , pp. 2868-2880
    • Albeda, S.M.1    Buck, C.A.2
  • 103
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
    • The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med 1994;330: 956-61.
    • (1994) N Engl J Med , vol.330 , pp. 956-961
  • 104
    • 0028345255 scopus 로고
    • Randomized trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months
    • Topol EJ, Califf RM, Weisman HF, et al. on behalf of the EPIC Investigators. Randomized trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months. Lancet 1994;343:881-886.
    • (1994) Lancet , vol.343 , pp. 881-886
    • Topol, E.J.1    Califf, R.M.2    Weisman, H.F.3
  • 105
  • 106
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization
    • The EPILOG Investigators. Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med 1997;336: 1689-1696.
    • (1997) N Engl J Med , vol.336 , pp. 1689-1696
  • 107
    • 23444458293 scopus 로고
    • Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina
    • Simoons ML, Jan de Boer M, van den Brand JBM, et al. and the European Cooperative Study Group. Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina. Circulation 1994;89:596-603.
    • (1994) Circulation , vol.89 , pp. 596-603
    • Simoons, M.L.1    De Jan Boer, M.2    Van Den Brand, J.B.M.3
  • 108
    • 0030918995 scopus 로고    scopus 로고
    • Randomized placebo-controlled trial of abciximab before and during coronary intervention, in refractory unstable angina: The CAPTURE study
    • The CAPTURE Investigators. Randomized placebo-controlled trial of abciximab before and during coronary intervention, in refractory unstable angina: The CAPTURE study. Lancet 1997;349:1429-1435.
    • (1997) Lancet , vol.349 , pp. 1429-1435
  • 109
  • 110
    • 0345553953 scopus 로고    scopus 로고
    • Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina. the Canadian Lamifiban Study
    • Théroux P, Kouz S, Roy L, et al. on behalf of the investigators. Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina. The Canadian Lamifiban Study. Circulation 1996;94:899-905.
    • (1996) Circulation , vol.94 , pp. 899-905
    • Théroux, P.1    Kouz, S.2    Roy, L.3
  • 111
    • 0032420213 scopus 로고    scopus 로고
    • Combined thrombolysis with the platelet glycoprotein IIb/IIIa inhibitor Lamifiban: Results of the platelet aggregation receptor antagonist dose investigation receptor antagonist dose investigations and reperfusion gain in myocardial infarction (PARADIGM) Trial
    • PARADIGM Investigators. Combined thrombolysis with the platelet glycoprotein IIb/IIIa inhibitor Lamifiban: Results of the platelet aggregation receptor antagonist dose investigation receptor antagonist dose investigations and reperfusion gain in myocardial infarction (PARADIGM) Trial. J Am Coll Cardiol 1998:32:2003-2010.
    • (1998) J am Coll Cardiol , vol.32 , pp. 2003-2010
  • 112
    • 0032560628 scopus 로고    scopus 로고
    • International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIa inhibitor), heparin, or both in unstable angina
    • PARAGON Investigators. International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIa inhibitor), heparin, or both in unstable angina. Circulation 1998;97:2386-2395).
    • (1998) Circulation , vol.97 , pp. 2386-2395
  • 113
    • 0342872079 scopus 로고    scopus 로고
    • Profound and sustained inhibition of platelet aggregation by fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men
    • Müller TH, Weisenberger H, Brickl R, Narjes H, Himmelsbach F, Krause J. Profound and sustained inhibition of platelet aggregation by fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men. Circulation 1997;96:1130-1138.
    • (1997) Circulation , vol.96 , pp. 1130-1138
    • Müller, T.H.1    Weisenberger, H.2    Brickl, R.3    Narjes, H.4    Himmelsbach, F.5    Krause, J.6
  • 114
    • 9044234402 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIb/IIIa blockade in high risk patients undergoing coronary angioplasty
    • Kereiakes DJ, Kleiman NS, Ambrose J, et al. Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIb/IIIa blockade in high risk patients undergoing coronary angioplasty. J Am Coll Cardiol 1996;27:536-542.
    • (1996) J am Coll Cardiol , vol.27 , pp. 536-542
    • Kereiakes, D.J.1    Kleiman, N.S.2    Ambrose, J.3
  • 115
    • 0343376106 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty
    • The RESTORE Investigators. Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation 1997;96:1445-1453.
    • (1997) Circulation , vol.96 , pp. 1445-1453
  • 116
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/IIIc receptor with tirofiban in unstable angina and non-Q wave MI
    • Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM Plus) Study Investigators. Inhibition of the platelet glycoprotein IIb/IIIc receptor with tirofiban in unstable angina and non-Q wave MI. N Eng J Med 1998;338:1488-1497.
    • (1998) N Eng J Med , vol.338 , pp. 1488-1497
  • 117
    • 2642654221 scopus 로고    scopus 로고
    • A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina
    • Platelet Receptor Inhibition in Ischemic Syndrome Management (PRISM) Study Investigators. A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. N Eng J Med 1998;338:1498-1505.
    • (1998) N Eng J Med , vol.338 , pp. 1498-1505
  • 118
    • 0030863733 scopus 로고    scopus 로고
    • Clinical pharmacology of eptifibatide
    • Phillips DR, Scarborough RM. Clinical pharmacology of eptifibatide. Am J Cardiol 1997;80(4A):11B-20B.
    • (1997) Am J Cardiol , vol.80 , Issue.4 A
    • Phillips, D.R.1    Scarborough, R.M.2
  • 119
    • 0028811436 scopus 로고
    • Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention
    • Harrington RA, Kleiman NS, Kottke-Marchant K, et al. Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention. Am J Cardiol 1995;76:1222-1227.
    • (1995) Am J Cardiol , vol.76 , pp. 1222-1227
    • Harrington, R.A.1    Kleiman, N.S.2    Kottke-Marchant, K.3
  • 120
    • 10244253888 scopus 로고    scopus 로고
    • Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina. a randomized multicenter trial
    • Schulman SP, Goldschmidt-Clermont PJ, Topol EJ, et al. Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina. A randomized multicenter trial. Circulation 1996;94:2083-2089.
    • (1996) Circulation , vol.94 , pp. 2083-2089
    • Schulman, S.P.1    Goldschmidt-Clermont, P.J.2    Topol, E.J.3
  • 121
    • 0030919511 scopus 로고    scopus 로고
    • Randomized placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II
    • The IMPACT-II Investigators. Randomized placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Lancet 1997; 349:1422-1428.
    • (1997) Lancet , vol.349 , pp. 1422-1428
  • 122
    • 16944362255 scopus 로고    scopus 로고
    • Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial
    • Ohman EM, Kleiman NS, Gacioch G, et al. for the IMPACT-AMI Investigators. Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. Circulation 1997;95:846-854.
    • (1997) Circulation , vol.95 , pp. 846-854
    • Ohman, E.M.1    Kleiman, N.S.2    Gacioch, G.3
  • 123
    • 0030749074 scopus 로고    scopus 로고
    • Design and methodology of the PURSUIT trial. Evaluating eptifibatide for acute ischemic coronary syndromes
    • Harrington RA. Design and methodology of the PURSUIT trial. Evaluating eptifibatide for acute ischemic coronary syndromes. Am J Cardiol 1997;80:34B-38B.
    • (1997) Am J Cardiol , vol.80
    • Harrington, R.A.1
  • 125
    • 17744404249 scopus 로고    scopus 로고
    • Sustained platelet glycoprotein IIb/IIIa blockade with oral Xemilofiban in 170 patients after coronary stent deployment
    • Kereiakes DJ, Kleiman N, Ferguson JJ, et al. Sustained platelet glycoprotein IIb/IIIa blockade with oral Xemilofiban in 170 patients after coronary stent deployment. Circulation 1997;96:1117-1121.
    • (1997) Circulation , vol.96 , pp. 1117-1121
    • Kereiakes, D.J.1    Kleiman, N.2    Ferguson, J.J.3
  • 126
    • 0029787575 scopus 로고    scopus 로고
    • Differential dose-response to oral Xemilofiban after antecedent intravenous abciximab. Administration for complex coronary intervention
    • Kereiakes DJ, Runyon JP, Kleiman NS, et al. Differential dose-response to oral Xemilofiban after antecedent intravenous abciximab. Administration for complex coronary intervention. Circulation 1996;94:906-910.
    • (1996) Circulation , vol.94 , pp. 906-910
    • Kereiakes, D.J.1    Runyon, J.P.2    Kleiman, N.S.3
  • 127
    • 0032578441 scopus 로고    scopus 로고
    • Pharmacodynamic efficacy, clinical safety, and outcomes following prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral X Xemilofiban: Results of a multicenter placebo-controlled randomized trial
    • in press
    • Kereiakes DJ, Kleiman NS, Ferguson JJ for the ORBIT Investigators. Pharmacodynamic efficacy, clinical safety, and outcomes following prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral X Xemilofiban: Results of a multicenter placebo-controlled randomized trial. Circulation 1998, in press.
    • (1998) Circulation
    • Kereiakes, D.J.1    Kleiman, N.S.2    Ferguson, J.J.3
  • 128
    • 0032477680 scopus 로고    scopus 로고
    • A randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients post an acute coronary syndrome: Results of the TIMI 12 trial
    • Cannon CP, McCabe CH, Borzak S for the TIMI 12 Investigators. A randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients post an acute coronary syndrome: Results of the TIMI 12 trial. Circulation 1998;97:340-349.
    • (1998) Circulation , vol.97 , pp. 340-349
    • Cannon, C.P.1    McCabe, Ch.2    Borzak, S.3
  • 129
    • 0028979135 scopus 로고
    • 2T purinoceptor antagonists: Definition of the role ADP in arterial thrombosis
    • 2T purinoceptor antagonists: Definition of the role ADP in arterial thrombosis. Trends Pharm Scie 1995;16:179-181.
    • (1995) Trends Pharm Scie , vol.16 , pp. 179-181
    • Humphries, R.G.1    Robertson, M.J.2    Leff, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.