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Volumn 82, Issue 1, 2013, Pages 1-15

Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: Facts and fiction

Author keywords

Antigen presentation; Autoimmunity; Inflammation; Major histocompatibility complex class II; Non professional antigen presenting cells

Indexed keywords

GAMMA INTERFERON; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NUCLEAR FACTOR Y;

EID: 84879777655     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/tan.12136     Document Type: Review
Times cited : (13)

References (121)
  • 1
    • 0027145904 scopus 로고
    • Control of MHC class II gene expression in autoimmune, infectious, and neoplastic diseases
    • Guardiola J, Maffei A. Control of MHC class II gene expression in autoimmune, infectious, and neoplastic diseases. Crit Rev Immunol 1993: 13: 247-68.
    • (1993) Crit Rev Immunol , vol.13 , pp. 247-268
    • Guardiola, J.1    Maffei, A.2
  • 2
    • 25844499012 scopus 로고    scopus 로고
    • Regulation of MHC class II gene expression by the class II transactivator
    • Reith W, LeibundGut-Landmann S, Waldburger JM. Regulation of MHC class II gene expression by the class II transactivator. Nat Rev Immunol 2005: 5: 793-806.
    • (2005) Nat Rev Immunol , vol.5 , pp. 793-806
    • Reith, W.1    LeibundGut-Landmann, S.2    Waldburger, J.M.3
  • 3
    • 84870212902 scopus 로고    scopus 로고
    • NLRC5: a key regulator of MHC class I-dependent immune responses
    • Kobayashi KS, Van den Elsen PJ. NLRC5: a key regulator of MHC class I-dependent immune responses. Nat Rev Immunol 2012: 12: 813-20.
    • (2012) Nat Rev Immunol , vol.12 , pp. 813-820
    • Kobayashi, K.S.1    Van den Elsen, P.J.2
  • 4
    • 0035920552 scopus 로고    scopus 로고
    • Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene
    • Waldburger JM, Suter T, Fontana A, Acha-Orbea H, Reith W. Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene. J Exp Med 2001: 194: 393-406.
    • (2001) J Exp Med , vol.194 , pp. 393-406
    • Waldburger, J.M.1    Suter, T.2    Fontana, A.3    Acha-Orbea, H.4    Reith, W.5
  • 5
    • 0037528761 scopus 로고    scopus 로고
    • Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells
    • Waldburger JM, Rossi S, Hollander GA, Rodewald HR, Reith W, Acha-Orbea H. Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells. Blood 2003: 101: 3550-9.
    • (2003) Blood , vol.101 , pp. 3550-3559
    • Waldburger, J.M.1    Rossi, S.2    Hollander, G.A.3    Rodewald, H.R.4    Reith, W.5    Acha-Orbea, H.6
  • 6
    • 51349101423 scopus 로고    scopus 로고
    • Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity
    • Irla M, Hugues S, Gill J et al. Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity. Immunity 2008: 29: 451-63.
    • (2008) Immunity , vol.29 , pp. 451-463
    • Irla, M.1    Hugues, S.2    Gill, J.3
  • 7
    • 0038316325 scopus 로고    scopus 로고
    • Anatomical basis of tolerance and immunity to intestinal antigens
    • Mowat AM. Anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol 2003: 3: 331-41.
    • (2003) Nat Rev Immunol , vol.3 , pp. 331-341
    • Mowat, A.M.1
  • 9
    • 0028828948 scopus 로고
    • Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma
    • Nilsen EM, Lundin KE, Krajci P, Scott H, Sollid LM, Brandtzaeg P. Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma. Gut 1995: 37: 766-76.
    • (1995) Gut , vol.37 , pp. 766-776
    • Nilsen, E.M.1    Lundin, K.E.2    Krajci, P.3    Scott, H.4    Sollid, L.M.5    Brandtzaeg, P.6
  • 10
    • 34548131585 scopus 로고    scopus 로고
    • The immune response in inflammatory bowel disease
    • Brown SJ, Mayer L. The immune response in inflammatory bowel disease. Am J Gastroenterol 2007: 102: 2058-69.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2058-2069
    • Brown, S.J.1    Mayer, L.2
  • 12
    • 0029041906 scopus 로고
    • Translocation of gliadin into HLA-DR antigen containing lysosomes in coeliac disease enterocytes
    • Zimmer KP, Poremba C, Weber P, Ciclitira PJ, Harms E. Translocation of gliadin into HLA-DR antigen containing lysosomes in coeliac disease enterocytes. Gut 1995: 36: 703-9.
    • (1995) Gut , vol.36 , pp. 703-709
    • Zimmer, K.P.1    Poremba, C.2    Weber, P.3    Ciclitira, P.J.4    Harms, E.5
  • 13
    • 0029070601 scopus 로고
    • Allogeneic lymphocyte proliferation stimulated by small intestine-derived epithelial cells
    • Li XC, Almawi W, Jevnikar A, Tucker J, Zhong R, Grant D. Allogeneic lymphocyte proliferation stimulated by small intestine-derived epithelial cells. Transplantation 1995: 60: 82-9.
    • (1995) Transplantation , vol.60 , pp. 82-89
    • Li, X.C.1    Almawi, W.2    Jevnikar, A.3    Tucker, J.4    Zhong, R.5    Grant, D.6
  • 14
    • 0026638615 scopus 로고
    • Epithelial cells bearing class II molecules stimulate allogeneic human colonic intraepithelial lymphocytes
    • Hoang P, Crotty B, Dalton HR, Jewell DP. Epithelial cells bearing class II molecules stimulate allogeneic human colonic intraepithelial lymphocytes. Gut 1992: 33: 1089-93.
    • (1992) Gut , vol.33 , pp. 1089-1093
    • Hoang, P.1    Crotty, B.2    Dalton, H.R.3    Jewell, D.P.4
  • 16
    • 0036830186 scopus 로고    scopus 로고
    • Human duodenal epithelial cells constitutively express molecular components of antigen presentation but not costimulatory molecules
    • Byrne B, Madrigal-Estebas L, McEvoy A et al. Human duodenal epithelial cells constitutively express molecular components of antigen presentation but not costimulatory molecules. Hum Immunol 2002: 63: 977-86.
    • (2002) Hum Immunol , vol.63 , pp. 977-986
    • Byrne, B.1    Madrigal-Estebas, L.2    McEvoy, A.3
  • 17
    • 0029021993 scopus 로고
    • Adhesion molecules intercellular adhesion molecule-1 (ICAM-1), ICAM-3 and B7 are not expressed by epithelium in normal or inflamed colon
    • Bloom S, Simmons D, Jewell DP. Adhesion molecules intercellular adhesion molecule-1 (ICAM-1), ICAM-3 and B7 are not expressed by epithelium in normal or inflamed colon. Clin Exp Immunol 1995: 101: 157-63.
    • (1995) Clin Exp Immunol , vol.101 , pp. 157-163
    • Bloom, S.1    Simmons, D.2    Jewell, D.P.3
  • 19
    • 77950556266 scopus 로고    scopus 로고
    • The CD40-CD40L pathway contributes to the proinflammatory function of intestinal epithelial cells in inflammatory bowel disease
    • Borcherding F, Nitschke M, Hundorfean G et al. The CD40-CD40L pathway contributes to the proinflammatory function of intestinal epithelial cells in inflammatory bowel disease. Am J Pathol 2010: 176: 1816-27.
    • (2010) Am J Pathol , vol.176 , pp. 1816-1827
    • Borcherding, F.1    Nitschke, M.2    Hundorfean, G.3
  • 20
    • 34447511700 scopus 로고    scopus 로고
    • Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma
    • Dotan I, Allez M, Nakazawa A, Brimnes J, Schulder-Katz M, Mayer L. Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma. Am J Physiol Gastrointest Liver Physiol 2007: 292: G1630-40.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Dotan, I.1    Allez, M.2    Nakazawa, A.3    Brimnes, J.4    Schulder-Katz, M.5    Mayer, L.6
  • 21
    • 0032874717 scopus 로고    scopus 로고
    • Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa
    • Nakazawa A, Watanabe M, Kanai T et al. Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa. Gastroenterology 1999: 117: 536-45.
    • (1999) Gastroenterology , vol.117 , pp. 536-545
    • Nakazawa, A.1    Watanabe, M.2    Kanai, T.3
  • 22
    • 84873734062 scopus 로고    scopus 로고
    • Lineage targeted MHC-II transgenic mice demonstrate the role of dendritic cells in bacterial-driven colitis
    • Maggio-Price L, Seamons A, Bielefeldt-Ohmann H et al. Lineage targeted MHC-II transgenic mice demonstrate the role of dendritic cells in bacterial-driven colitis. Inflamm Bowel Dis 2013: 19: 174-84.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 174-184
    • Maggio-Price, L.1    Seamons, A.2    Bielefeldt-Ohmann, H.3
  • 23
    • 0024458204 scopus 로고
    • Murine enterocytes can present soluble antigen to specific class II-restricted CD4+ T cells
    • Kaiserlian D, Vidal K, Revillard JP. Murine enterocytes can present soluble antigen to specific class II-restricted CD4+ T cells. Eur J Immunol 1989: 19: 1513-6.
    • (1989) Eur J Immunol , vol.19 , pp. 1513-1516
    • Kaiserlian, D.1    Vidal, K.2    Revillard, J.P.3
  • 24
    • 0032958705 scopus 로고    scopus 로고
    • Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
    • Schmitz H, Barmeyer C, Fromm M et al. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 1999: 116: 301-9.
    • (1999) Gastroenterology , vol.116 , pp. 301-309
    • Schmitz, H.1    Barmeyer, C.2    Fromm, M.3
  • 25
    • 78650085568 scopus 로고    scopus 로고
    • Function of the intestinal epithelium and its dysregulation in inflammatory bowel disease
    • Henderson P, van Limbergen JE, Schwarze J, Wilson DC. Function of the intestinal epithelium and its dysregulation in inflammatory bowel disease. Inflamm Bowel Dis 2011: 17: 382-95.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 382-395
    • Henderson, P.1    van Limbergen, J.E.2    Schwarze, J.3    Wilson, D.C.4
  • 26
    • 0032930311 scopus 로고    scopus 로고
    • Polarized expression and function of the costimulatory molecule CD58 on human intestinal epithelial cells
    • Framson PE, Cho DH, Lee LY, Hershberg RM. Polarized expression and function of the costimulatory molecule CD58 on human intestinal epithelial cells. Gastroenterology 1999: 116: 1054-62.
    • (1999) Gastroenterology , vol.116 , pp. 1054-1062
    • Framson, P.E.1    Cho, D.H.2    Lee, L.Y.3    Hershberg, R.M.4
  • 27
    • 2142711024 scopus 로고    scopus 로고
    • The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells
    • Nakazawa A, Dotan I, Brimnes J et al. The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. Gastroenterology 2004: 126: 1347-57.
    • (2004) Gastroenterology , vol.126 , pp. 1347-1357
    • Nakazawa, A.1    Dotan, I.2    Brimnes, J.3
  • 28
    • 58849154126 scopus 로고    scopus 로고
    • CD4+Foxp3+ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cells
    • Westendorf AM, Fleissner D, Groebe L et al. CD4+Foxp3+ regulatory T cell expansion induced by antigen-driven interaction with intestinal epithelial cells independent of local dendritic cells. Gut 2009: 58: 211-9.
    • (2009) Gut , vol.58 , pp. 211-219
    • Westendorf, A.M.1    Fleissner, D.2    Groebe, L.3
  • 32
    • 33644544110 scopus 로고    scopus 로고
    • The liver as an immunological organ
    • Racanelli V, Rehermann B. The liver as an immunological organ. Hepatology 2006: 43: S54-62.
    • (2006) Hepatology , vol.43
    • Racanelli, V.1    Rehermann, B.2
  • 33
    • 0028012009 scopus 로고
    • Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver
    • Toyonaga T, Hino O, Sugai S et al. Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver. Proc Natl Acad Sci U S A 1994: 91: 614-8.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 614-618
    • Toyonaga, T.1    Hino, O.2    Sugai, S.3
  • 34
    • 0037698820 scopus 로고    scopus 로고
    • MHC class II-expressing hepatocytes function as antigen-presenting cells and activate specific CD4 T lymphocyutes
    • Herkel J, Jagemann B, Wiegard C et al. MHC class II-expressing hepatocytes function as antigen-presenting cells and activate specific CD4 T lymphocyutes. Hepatology 2003: 37: 1079-85.
    • (2003) Hepatology , vol.37 , pp. 1079-1085
    • Herkel, J.1    Jagemann, B.2    Wiegard, C.3
  • 35
    • 36549013250 scopus 로고    scopus 로고
    • Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearance
    • Wiegard C, Wolint P, Frenzel C et al. Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearance. Gastroenterology 2007: 133: 2010-8.
    • (2007) Gastroenterology , vol.133 , pp. 2010-2018
    • Wiegard, C.1    Wolint, P.2    Frenzel, C.3
  • 36
    • 0029978748 scopus 로고    scopus 로고
    • Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells
    • Lohse AW, Knolle PA, Bilo K et al. Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells. Gastroenterology 1996: 110: 1175-81.
    • (1996) Gastroenterology , vol.110 , pp. 1175-1181
    • Lohse, A.W.1    Knolle, P.A.2    Bilo, K.3
  • 37
    • 0141491358 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells: a new type of organ-resident antigen-presenting cell
    • Limmer A, Knolle PA. Liver sinusoidal endothelial cells: a new type of organ-resident antigen-presenting cell. Arch Immunol Ther Exp (Warsz) 2001: 49 (Suppl 1): S7-11.
    • (2001) Arch Immunol Ther Exp (Warsz) , vol.49 , Issue.SUPPL 1
    • Limmer, A.1    Knolle, P.A.2
  • 38
    • 0033002962 scopus 로고    scopus 로고
    • Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells
    • Knolle PA, Schmitt E, Jin S et al. Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells. Gastroenterology 1999: 116: 1428-40.
    • (1999) Gastroenterology , vol.116 , pp. 1428-1440
    • Knolle, P.A.1    Schmitt, E.2    Jin, S.3
  • 39
    • 0031768675 scopus 로고    scopus 로고
    • IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules
    • Knolle PA, Uhrig A, Hegenbarth S et al. IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules. Clin Exp Immunol 1998: 114: 427-33.
    • (1998) Clin Exp Immunol , vol.114 , pp. 427-433
    • Knolle, P.A.1    Uhrig, A.2    Hegenbarth, S.3
  • 41
    • 73149098744 scopus 로고    scopus 로고
    • Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis
    • Kruse N, Neumann K, Schrage A et al. Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis. Hepatology 2009: 50: 1904-13.
    • (2009) Hepatology , vol.50 , pp. 1904-1913
    • Kruse, N.1    Neumann, K.2    Schrage, A.3
  • 42
    • 33846212347 scopus 로고    scopus 로고
    • Ito cells are liver-resident antigen-presenting cells for activating T cell responses
    • Winau F, Hegasy G, Weiskirchen R et al. Ito cells are liver-resident antigen-presenting cells for activating T cell responses. Immunity 2007: 26: 117-29.
    • (2007) Immunity , vol.26 , pp. 117-129
    • Winau, F.1    Hegasy, G.2    Weiskirchen, R.3
  • 43
    • 33751000216 scopus 로고    scopus 로고
    • In vivo immune modulatory activity of hepatic stellate cells in mice
    • Chen CH, Kuo LM, Chang Y et al. In vivo immune modulatory activity of hepatic stellate cells in mice. Hepatology 2006: 44: 1171-81.
    • (2006) Hepatology , vol.44 , pp. 1171-1181
    • Chen, C.H.1    Kuo, L.M.2    Chang, Y.3
  • 45
    • 24744462303 scopus 로고    scopus 로고
    • Autoimmunity and interstitial lung disease
    • Jindal SK, Agarwal R. Autoimmunity and interstitial lung disease. Curr Opin Pulm Med 2005: 11: 438-46.
    • (2005) Curr Opin Pulm Med , vol.11 , pp. 438-446
    • Jindal, S.K.1    Agarwal, R.2
  • 46
    • 72949093686 scopus 로고    scopus 로고
    • Identification of an autoantigen demonstrates a link between interstitial lung disease and a defect in central tolerance
    • Shum AK, DeVoss J, Tan CL et al. Identification of an autoantigen demonstrates a link between interstitial lung disease and a defect in central tolerance. Sci Transl Med 2009: 1: 9ra20.
    • (2009) Sci Transl Med , vol.1
    • Shum, A.K.1    DeVoss, J.2    Tan, C.L.3
  • 47
    • 77958116477 scopus 로고    scopus 로고
    • Cutting edge: MHC class II expression by pulmonary nonhematopoietic cells plays a critical role in controlling local inflammatory responses
    • Kreisel D, Richardson SB, Li W et al. Cutting edge: MHC class II expression by pulmonary nonhematopoietic cells plays a critical role in controlling local inflammatory responses. J Immunol 2010: 185: 3809-13.
    • (2010) J Immunol , vol.185 , pp. 3809-3813
    • Kreisel, D.1    Richardson, S.B.2    Li, W.3
  • 48
    • 0027398111 scopus 로고
    • Regulation of antigen-presenting cell function(s) in lung and airway tissues
    • Holt PG. Regulation of antigen-presenting cell function(s) in lung and airway tissues. Eur Respir J 1993: 6: 120-9.
    • (1993) Eur Respir J , vol.6 , pp. 120-129
    • Holt, P.G.1
  • 49
    • 0025912335 scopus 로고
    • Human bronchial epithelial cells modulate CD3 and mitogen-induced DNA synthesis in T cells but function poorly as antigen-presenting cells compared to pulmonary macrophages
    • Mezzetti M, Soloperto M, Fasoli A, Mattoli S. Human bronchial epithelial cells modulate CD3 and mitogen-induced DNA synthesis in T cells but function poorly as antigen-presenting cells compared to pulmonary macrophages. J Allergy Clin Immunol 1991: 87: 930-8.
    • (1991) J Allergy Clin Immunol , vol.87 , pp. 930-938
    • Mezzetti, M.1    Soloperto, M.2    Fasoli, A.3    Mattoli, S.4
  • 51
    • 79959334504 scopus 로고    scopus 로고
    • Pathophysiology of allergic inflammation
    • Barnes PJ. Pathophysiology of allergic inflammation. Immunol Rev 2011: 242: 31-50.
    • (2011) Immunol Rev , vol.242 , pp. 31-50
    • Barnes, P.J.1
  • 53
    • 84860175382 scopus 로고    scopus 로고
    • Downregulation of integrin beta4 decreases the ability of airway epithelial cells to present antigens
    • Liu C, Qin X, Liu H, Xiang Y. Downregulation of integrin beta4 decreases the ability of airway epithelial cells to present antigens. PLoS One 2012: 7: e32060.
    • (2012) PLoS One , vol.7
    • Liu, C.1    Qin, X.2    Liu, H.3    Xiang, Y.4
  • 54
    • 0024690462 scopus 로고
    • Characterization of two major populations of lung fibroblasts: distinguishing morphology and discordant display of Thy 1 and class II MHC
    • Phipps RP, Penney DP, Keng P et al. Characterization of two major populations of lung fibroblasts: distinguishing morphology and discordant display of Thy 1 and class II MHC. Am J Respir Cell Mol Biol 1989: 1: 65-74.
    • (1989) Am J Respir Cell Mol Biol , vol.1 , pp. 65-74
    • Phipps, R.P.1    Penney, D.P.2    Keng, P.3
  • 55
    • 82955211453 scopus 로고    scopus 로고
    • CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes
    • Haskins K, Cooke A. CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes. Curr Opin Immunol 2011: 23: 739-45.
    • (2011) Curr Opin Immunol , vol.23 , pp. 739-745
    • Haskins, K.1    Cooke, A.2
  • 56
    • 84872734510 scopus 로고    scopus 로고
    • The environment and the origins of islet autoimmunity and Type 1 diabetes
    • Eringsmark Regnell S, Lernmark A. The environment and the origins of islet autoimmunity and Type 1 diabetes. Diabet Med 2013: 30: 155-60.
    • (2013) Diabet Med , vol.30 , pp. 155-160
    • Eringsmark Regnell, S.1    Lernmark, A.2
  • 57
    • 0022291728 scopus 로고
    • Immunology of insulin-dependent diabetes mellitus
    • Rossini AA, Mordes JP, Like AA. Immunology of insulin-dependent diabetes mellitus. Annu Rev Immunol 1985: 3: 289-320.
    • (1985) Annu Rev Immunol , vol.3 , pp. 289-320
    • Rossini, A.A.1    Mordes, J.P.2    Like, A.A.3
  • 58
    • 0033048174 scopus 로고    scopus 로고
    • Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice
    • Liu J, Purdy LE, Rabinovitch S, Jevnikar AM, Elliott JF. Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice. Diabetes 1999: 48: 469-77.
    • (1999) Diabetes , vol.48 , pp. 469-477
    • Liu, J.1    Purdy, L.E.2    Rabinovitch, S.3    Jevnikar, A.M.4    Elliott, J.F.5
  • 59
    • 0028365499 scopus 로고
    • Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice
    • Guerder S, Picarella DE, Linsley PS, Flavell RA. Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice. Proc Natl Acad Sci U S A 1994: 91: 5138-42.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5138-5142
    • Guerder, S.1    Picarella, D.E.2    Linsley, P.S.3    Flavell, R.A.4
  • 60
    • 0021875480 scopus 로고
    • In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
    • Bottazzo GF, Dean BM, McNally JM, MacKay EH, Swift PG, Gamble DR. In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis. N Engl J Med 1985: 313: 353-60.
    • (1985) N Engl J Med , vol.313 , pp. 353-360
    • Bottazzo, G.F.1    Dean, B.M.2    McNally, J.M.3    MacKay, E.H.4    Swift, P.G.5    Gamble, D.R.6
  • 61
    • 10744228962 scopus 로고    scopus 로고
    • Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes
    • Walter U, Toepfer T, Dittmar KE et al. Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes. Diabetologia 2003: 46: 1106-14.
    • (2003) Diabetologia , vol.46 , pp. 1106-1114
    • Walter, U.1    Toepfer, T.2    Dittmar, K.E.3
  • 62
    • 0023105107 scopus 로고
    • HLA class II induction in human islet cells by interferon-gamma plus tumour necrosis factor or lymphotoxin
    • Pujol-Borrell R, Todd I, Doshi M et al. HLA class II induction in human islet cells by interferon-gamma plus tumour necrosis factor or lymphotoxin. Nature 1987: 326: 304-6.
    • (1987) Nature , vol.326 , pp. 304-306
    • Pujol-Borrell, R.1    Todd, I.2    Doshi, M.3
  • 63
    • 0023837232 scopus 로고
    • IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse
    • Campbell IL, Oxbrow L, Koulmanda M, Harrison LC. IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse. J Immunol 1988: 140: 1111-6.
    • (1988) J Immunol , vol.140 , pp. 1111-1116
    • Campbell, I.L.1    Oxbrow, L.2    Koulmanda, M.3    Harrison, L.C.4
  • 64
    • 0022902503 scopus 로고
    • Induction of class II MHC antigens in vitro on pancreatic B cells isolated from BB/E rats
    • Walker R, Cooke A, Bone AJ, Dean BM, van der Meide P, Baird JD. Induction of class II MHC antigens in vitro on pancreatic B cells isolated from BB/E rats. Diabetologia 1986: 29: 749-51.
    • (1986) Diabetologia , vol.29 , pp. 749-751
    • Walker, R.1    Cooke, A.2    Bone, A.J.3    Dean, B.M.4    van der Meide, P.5    Baird, J.D.6
  • 65
    • 0024281396 scopus 로고
    • Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells
    • Lo D, Burkly LC, Widera G et al. Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell 1988: 53: 159-68.
    • (1988) Cell , vol.53 , pp. 159-168
    • Lo, D.1    Burkly, L.C.2    Widera, G.3
  • 66
    • 0023841728 scopus 로고
    • Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma
    • Sarvetnick N, Liggitt D, Pitts SL, Hansen SE, Stewart TA. Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 1988: 52: 773-82.
    • (1988) Cell , vol.52 , pp. 773-782
    • Sarvetnick, N.1    Liggitt, D.2    Pitts, S.L.3    Hansen, S.E.4    Stewart, T.A.5
  • 68
    • 0024372274 scopus 로고
    • Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant
    • Bohme J, Haskins K, Stecha P et al. Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant. Science 1989: 244: 1179-83.
    • (1989) Science , vol.244 , pp. 1179-1183
    • Bohme, J.1    Haskins, K.2    Stecha, P.3
  • 69
    • 21344441928 scopus 로고    scopus 로고
    • The influence of the major histocompatibility complex on development of autoimmune diabetes in RIP-B7.1 mice
    • Wong FS, Du W, Thomas IJ, Wen L. The influence of the major histocompatibility complex on development of autoimmune diabetes in RIP-B7.1 mice. Diabetes 2005: 54: 2032-40.
    • (2005) Diabetes , vol.54 , pp. 2032-2040
    • Wong, F.S.1    Du, W.2    Thomas, I.J.3    Wen, L.4
  • 70
    • 84875244645 scopus 로고    scopus 로고
    • Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease
    • Codarri L, Greter M, Becher B. Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease. Trends Immunol 2013: 34: 114-9.
    • (2013) Trends Immunol , vol.34 , pp. 114-119
    • Codarri, L.1    Greter, M.2    Becher, B.3
  • 71
    • 20044376483 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis repressed by microglial paralysis
    • Heppner FL, Greter M, Marino D et al. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med 2005: 11: 146-52.
    • (2005) Nat Med , vol.11 , pp. 146-152
    • Heppner, F.L.1    Greter, M.2    Marino, D.3
  • 72
    • 0021191999 scopus 로고
    • Astrocytes present myelin basic protein to encephalitogenic T-cell lines
    • Fontana A, Fierz W, Wekerle H. Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature 1984: 307: 273-6.
    • (1984) Nature , vol.307 , pp. 273-276
    • Fontana, A.1    Fierz, W.2    Wekerle, H.3
  • 73
    • 0034676994 scopus 로고    scopus 로고
    • Astrocytes in chronic active multiple sclerosis plaques express MHC class II molecules
    • Zeinstra E, Wilczak N, Streefland C, De Keyser J. Astrocytes in chronic active multiple sclerosis plaques express MHC class II molecules. Neuroreport 2000: 11: 89-91.
    • (2000) Neuroreport , vol.11 , pp. 89-91
    • Zeinstra, E.1    Wilczak, N.2    Streefland, C.3    De Keyser, J.4
  • 74
    • 0025828986 scopus 로고
    • Major histocompatibility complex-expressing nonhematopoietic astroglial cells prime only CD8+ T lymphocytes: astroglial cells as perpetuators but not initiators of CD4+ T cell responses in the central nervous system
    • Sedgwick JD, Mossner R, Schwender S, ter Meulen V. Major histocompatibility complex-expressing nonhematopoietic astroglial cells prime only CD8+ T lymphocytes: astroglial cells as perpetuators but not initiators of CD4+ T cell responses in the central nervous system. J Exp Med 1991: 173: 1235-46.
    • (1991) J Exp Med , vol.173 , pp. 1235-1246
    • Sedgwick, J.D.1    Mossner, R.2    Schwender, S.3    ter Meulen, V.4
  • 75
    • 33644948466 scopus 로고    scopus 로고
    • Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice
    • Kort JJ, Kawamura K, Fugger L, Weissert R, Forsthuber TG. Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice. J Neuroimmunol 2006: 173: 23-34.
    • (2006) J Neuroimmunol , vol.173 , pp. 23-34
    • Kort, J.J.1    Kawamura, K.2    Fugger, L.3    Weissert, R.4    Forsthuber, T.G.5
  • 76
    • 0037308678 scopus 로고    scopus 로고
    • Reactive astrocytes in chronic active lesions of multiple sclerosis express co-stimulatory molecules B7-1 and B7-2
    • Zeinstra E, Wilczak N, De Keyser J. Reactive astrocytes in chronic active lesions of multiple sclerosis express co-stimulatory molecules B7-1 and B7-2. J Neuroimmunol 2003: 135: 166-71.
    • (2003) J Neuroimmunol , vol.135 , pp. 166-171
    • Zeinstra, E.1    Wilczak, N.2    De Keyser, J.3
  • 77
    • 0023858304 scopus 로고
    • Interferon-gamma and Ia antigen are present on astrocytes in active chronic multiple sclerosis lesions
    • Traugott U, Lebon P. Interferon-gamma and Ia antigen are present on astrocytes in active chronic multiple sclerosis lesions. J Neurol Sci 1988: 84: 257-64.
    • (1988) J Neurol Sci , vol.84 , pp. 257-264
    • Traugott, U.1    Lebon, P.2
  • 78
    • 0025033649 scopus 로고
    • Cellular immune response in multiple sclerosis plaques
    • Boyle EA, McGeer PL. Cellular immune response in multiple sclerosis plaques. Am J Pathol 1990: 137: 575-84.
    • (1990) Am J Pathol , vol.137 , pp. 575-584
    • Boyle, E.A.1    McGeer, P.L.2
  • 79
    • 0028231281 scopus 로고
    • Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions
    • Bo L, Mork S, Kong PA, Nyland H, Pardo CA, Trapp BD. Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J Neuroimmunol 1994: 51: 135-46.
    • (1994) J Neuroimmunol , vol.51 , pp. 135-146
    • Bo, L.1    Mork, S.2    Kong, P.A.3    Nyland, H.4    Pardo, C.A.5    Trapp, B.D.6
  • 80
    • 0033027434 scopus 로고    scopus 로고
    • Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the the central nervous system: astrocytes fail to express major histocompatibility complex class I and II molecules
    • Horwitz MS, Evans CF, Klier FG, Oldstone MB. Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the the central nervous system: astrocytes fail to express major histocompatibility complex class I and II molecules. Lab Invest 1999: 79: 235-42.
    • (1999) Lab Invest , vol.79 , pp. 235-242
    • Horwitz, M.S.1    Evans, C.F.2    Klier, F.G.3    Oldstone, M.B.4
  • 81
    • 0037114162 scopus 로고    scopus 로고
    • The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune disease
    • Stuve O, Youssef S, Slavin AJ et al. The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune disease. J Immunol 2002: 169: 6720-32.
    • (2002) J Immunol , vol.169 , pp. 6720-6732
    • Stuve, O.1    Youssef, S.2    Slavin, A.J.3
  • 82
    • 0027244759 scopus 로고
    • Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes
    • Fabry Z, Sandor M, Gajewski TF et al. Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes. J Immunol 1993: 151: 38-47.
    • (1993) J Immunol , vol.151 , pp. 38-47
    • Fabry, Z.1    Sandor, M.2    Gajewski, T.F.3
  • 84
    • 27744470765 scopus 로고    scopus 로고
    • A novel mechanism of neutrophil recruitment in a coculture model of the rheumatoid synovium
    • Lally F, Smith E, Filer A et al. A novel mechanism of neutrophil recruitment in a coculture model of the rheumatoid synovium. Arthritis Rheum 2005: 52: 3460-9.
    • (2005) Arthritis Rheum , vol.52 , pp. 3460-3469
    • Lally, F.1    Smith, E.2    Filer, A.3
  • 86
    • 0021874722 scopus 로고
    • Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis
    • Amento EP, Bhan AK, McCullagh KG, Krane SM. Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis. J Clin Invest 1985: 76: 837-48.
    • (1985) J Clin Invest , vol.76 , pp. 837-848
    • Amento, E.P.1    Bhan, A.K.2    McCullagh, K.G.3    Krane, S.M.4
  • 87
    • 0023637267 scopus 로고
    • Synovial fluid mononuclear cells exhibit a spontaneous HLA-DR driven proliferative response
    • Duke O, Gordon Y, Panayi GS. Synovial fluid mononuclear cells exhibit a spontaneous HLA-DR driven proliferative response. Clin Exp Immunol 1987: 70: 10-7.
    • (1987) Clin Exp Immunol , vol.70 , pp. 10-17
    • Duke, O.1    Gordon, Y.2    Panayi, G.S.3
  • 88
    • 34248595623 scopus 로고    scopus 로고
    • Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes
    • Tran CN, Davis MJ, Tesmer LA et al. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum 2007: 56: 1497-506.
    • (2007) Arthritis Rheum , vol.56 , pp. 1497-1506
    • Tran, C.N.1    Davis, M.J.2    Tesmer, L.A.3
  • 89
    • 49149089228 scopus 로고    scopus 로고
    • Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3
    • Tran CN, Thacker SG, Louie DM et al. Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J Immunol 2008: 180: 2989-98.
    • (2008) J Immunol , vol.180 , pp. 2989-2998
    • Tran, C.N.1    Thacker, S.G.2    Louie, D.M.3
  • 91
    • 33749237679 scopus 로고    scopus 로고
    • Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis
    • Kanazawa S, Ota S, Sekine C et al. Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis. Proc Natl Acad Sci U S A 2006: 103: 14465-70.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14465-14470
    • Kanazawa, S.1    Ota, S.2    Sekine, C.3
  • 92
    • 80155204630 scopus 로고    scopus 로고
    • Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis
    • Waldburger JM, Palmer G, Seemayer C et al. Autoimmunity and inflammation are independent of class II transactivator type PIV-dependent class II major histocompatibility complex expression in peripheral tissues during collagen-induced arthritis. Arthritis Rheum 2011: 63: 3354-63.
    • (2011) Arthritis Rheum , vol.63 , pp. 3354-3363
    • Waldburger, J.M.1    Palmer, G.2    Seemayer, C.3
  • 93
    • 0033922176 scopus 로고    scopus 로고
    • Lack of CD80 expression by fibroblast-like synoviocytes leading to anergy in T lymphocytes
    • Corrigall VM, Solau-Gervais E, Panayi GS. Lack of CD80 expression by fibroblast-like synoviocytes leading to anergy in T lymphocytes. Arthritis Rheum 2000: 43: 1606-15.
    • (2000) Arthritis Rheum , vol.43 , pp. 1606-1615
    • Corrigall, V.M.1    Solau-Gervais, E.2    Panayi, G.S.3
  • 94
    • 71749101248 scopus 로고    scopus 로고
    • Autoimmune myocarditis: past, present and future
    • Leuschner F, Katus HA, Kaya Z. Autoimmune myocarditis: past, present and future. J Autoimmun 2009: 33: 282-9.
    • (2009) J Autoimmun , vol.33 , pp. 282-289
    • Leuschner, F.1    Katus, H.A.2    Kaya, Z.3
  • 95
    • 0025091673 scopus 로고
    • Inappropriate major histocompatibility complex expression on cardiac tissue in dilated cardiomyopathy. Relevance for autoimmunity?
    • Caforio AL, Stewart JT, Bonifacio E et al. Inappropriate major histocompatibility complex expression on cardiac tissue in dilated cardiomyopathy. Relevance for autoimmunity? J Autoimmun 1990: 3: 187-200.
    • (1990) J Autoimmun , vol.3 , pp. 187-200
    • Caforio, A.L.1    Stewart, J.T.2    Bonifacio, E.3
  • 96
    • 0026049740 scopus 로고
    • Expression of MHC class I and II antigens and the Il-2 receptor in rejection, myocarditis and dilated cardiomyopathy
    • Hufnagel G, Maisch B. Expression of MHC class I and II antigens and the Il-2 receptor in rejection, myocarditis and dilated cardiomyopathy. Eur Heart J 1991: 12 (Suppl D): 137-40.
    • (1991) Eur Heart J , vol.12 , Issue.SUPPL D , pp. 137-140
    • Hufnagel, G.1    Maisch, B.2
  • 97
    • 33646119669 scopus 로고    scopus 로고
    • Immunoregulatory effects of atorvastatin on experimental autoimmune myocarditis in Lewis rats
    • Li WM, Liu W, Gao C, Zhou BG. Immunoregulatory effects of atorvastatin on experimental autoimmune myocarditis in Lewis rats. Immunol Cell Biol 2006: 84: 274-80.
    • (2006) Immunol Cell Biol , vol.84 , pp. 274-280
    • Li, W.M.1    Liu, W.2    Gao, C.3    Zhou, B.G.4
  • 98
    • 16244417243 scopus 로고    scopus 로고
    • Successful treatment of experimental autoimmune myocarditis by adenovirus-mediated gene transfer of antisense CIITA
    • Cai G, Zhang J, Liu L, Shen Q. Successful treatment of experimental autoimmune myocarditis by adenovirus-mediated gene transfer of antisense CIITA. J Mol Cell Cardiol 2005: 38: 593-605.
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 593-605
    • Cai, G.1    Zhang, J.2    Liu, L.3    Shen, Q.4
  • 99
    • 0028266381 scopus 로고
    • Regulation of the costimulator B7, not class II major histocompatibility complex, restricts the ability of murine kidney tubule cells to stimulate CD4+ T cells
    • Hagerty DT, Evavold BD, Allen PM. Regulation of the costimulator B7, not class II major histocompatibility complex, restricts the ability of murine kidney tubule cells to stimulate CD4+ T cells. J Clin Invest 1994: 93: 1208-15.
    • (1994) J Clin Invest , vol.93 , pp. 1208-1215
    • Hagerty, D.T.1    Evavold, B.D.2    Allen, P.M.3
  • 100
    • 0020524119 scopus 로고
    • Ia antigens in rat kidney, with special reference to their expression in tubular epithelium
    • Mayrhofer G, Schon-Hegrad MA. Ia antigens in rat kidney, with special reference to their expression in tubular epithelium. J Exp Med 1983: 157: 2097-109.
    • (1983) J Exp Med , vol.157 , pp. 2097-2109
    • Mayrhofer, G.1    Schon-Hegrad, M.A.2
  • 101
    • 0037408418 scopus 로고    scopus 로고
    • Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression
    • Muczynski KA, Ekle DM, Coder DM, Anderson SK. Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression. J Am Soc Nephrol 2003: 14: 1336-48.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1336-1348
    • Muczynski, K.A.1    Ekle, D.M.2    Coder, D.M.3    Anderson, S.K.4
  • 102
    • 0028326095 scopus 로고
    • Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice
    • Jevnikar AM, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J Exp Med 1994: 179: 1137-43.
    • (1994) J Exp Med , vol.179 , pp. 1137-1143
    • Jevnikar, A.M.1    Grusby, M.J.2    Glimcher, L.H.3
  • 103
    • 0026605255 scopus 로고
    • Processing and presentation of self and foreign antigens by the renal proximal tubule
    • Hagerty DT, Allen PM. Processing and presentation of self and foreign antigens by the renal proximal tubule. J Immunol 1992: 148: 2324-30.
    • (1992) J Immunol , vol.148 , pp. 2324-2330
    • Hagerty, D.T.1    Allen, P.M.2
  • 104
    • 0033956769 scopus 로고    scopus 로고
    • Central role for interferon-gamma receptor in the regulation of renal MHC expression
    • Takei Y, Sims TN, Urmson J, Halloran PF. Central role for interferon-gamma receptor in the regulation of renal MHC expression. J Am Soc Nephrol 2000: 11: 250-61.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 250-261
    • Takei, Y.1    Sims, T.N.2    Urmson, J.3    Halloran, P.F.4
  • 105
    • 0031136958 scopus 로고    scopus 로고
    • IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo
    • Hobart M, Ramassar V, Goes N, Urmson J, Halloran PF. IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo. J Immunol 1997: 158: 4260-9.
    • (1997) J Immunol , vol.158 , pp. 4260-4269
    • Hobart, M.1    Ramassar, V.2    Goes, N.3    Urmson, J.4    Halloran, P.F.5
  • 106
    • 0035849793 scopus 로고    scopus 로고
    • Impaired class II transactivator expression in mice lacking interferon regulatory factor-2
    • Xi H, Goodwin B, Shepherd AT, Blanck G. Impaired class II transactivator expression in mice lacking interferon regulatory factor-2. Oncogene 2001: 20: 4219-27.
    • (2001) Oncogene , vol.20 , pp. 4219-4227
    • Xi, H.1    Goodwin, B.2    Shepherd, A.T.3    Blanck, G.4
  • 107
    • 0024551602 scopus 로고
    • Glomerular mesangial cells in local inflammation. Induction of the expression of MHC class II antigens by IFN-gamma
    • Martin M, Schwinzer R, Schellekens H, Resch K. Glomerular mesangial cells in local inflammation. Induction of the expression of MHC class II antigens by IFN-gamma. J Immunol 1989: 142: 1887-94.
    • (1989) J Immunol , vol.142 , pp. 1887-1894
    • Martin, M.1    Schwinzer, R.2    Schellekens, H.3    Resch, K.4
  • 108
    • 20944444925 scopus 로고    scopus 로고
    • STAT1-independent down-regulation of interferon-gamma-induced class II transactivator and HLA-DR expression by transforming growth factor beta-1 in human glomerular endothelial cells
    • Yang WS, Han NJ, Kim CS et al. STAT1-independent down-regulation of interferon-gamma-induced class II transactivator and HLA-DR expression by transforming growth factor beta-1 in human glomerular endothelial cells. Nephron Exp Nephrol 2005: 100: e124-31.
    • (2005) Nephron Exp Nephrol , vol.100
    • Yang, W.S.1    Han, N.J.2    Kim, C.S.3
  • 110
    • 0026739444 scopus 로고
    • Intraglomerular expression of MHC class II and Ki-67 antigens and serum gamma-interferon levels in IgA nephropathy
    • Yokoyama H, Takaeda M, Wada T et al. Intraglomerular expression of MHC class II and Ki-67 antigens and serum gamma-interferon levels in IgA nephropathy. Nephron 1992: 62: 169-75.
    • (1992) Nephron , vol.62 , pp. 169-175
    • Yokoyama, H.1    Takaeda, M.2    Wada, T.3
  • 111
    • 0030357956 scopus 로고    scopus 로고
    • Lupus nephritis in the absence of renal major histocompatibility complex class I and class II molecules
    • Mukherjee R, Zhang Z, Zhong R, Yin ZQ, Roopenian DC, Jevnikar AM. Lupus nephritis in the absence of renal major histocompatibility complex class I and class II molecules. J Am Soc Nephrol 1996: 7: 2445-52.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2445-2452
    • Mukherjee, R.1    Zhang, Z.2    Zhong, R.3    Yin, Z.Q.4    Roopenian, D.C.5    Jevnikar, A.M.6
  • 112
    • 0032479962 scopus 로고    scopus 로고
    • Major histocompatibility complex class II expression by intrinsic renal cells is required for crescentic glomerulonephritis
    • Li S, Kurts C, Kontgen F, Holdsworth SR, Tipping PG. Major histocompatibility complex class II expression by intrinsic renal cells is required for crescentic glomerulonephritis. J Exp Med 1998: 188: 597-602.
    • (1998) J Exp Med , vol.188 , pp. 597-602
    • Li, S.1    Kurts, C.2    Kontgen, F.3    Holdsworth, S.R.4    Tipping, P.G.5
  • 113
    • 0021965499 scopus 로고
    • Follicular dendritic cells in suspension: identification, enrichment, and initial characterization indicating immune complex trapping and lack of adherence and phagocytic activity
    • Schnizlein CT, Kosco MH, Szakal AK, Tew JG. Follicular dendritic cells in suspension: identification, enrichment, and initial characterization indicating immune complex trapping and lack of adherence and phagocytic activity. J Immunol 1985: 134: 1360-8.
    • (1985) J Immunol , vol.134 , pp. 1360-1368
    • Schnizlein, C.T.1    Kosco, M.H.2    Szakal, A.K.3    Tew, J.G.4
  • 114
    • 78649510272 scopus 로고    scopus 로고
    • The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs
    • Turley SJ, Fletcher AL, Elpek KG. The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs. Nat Rev Immunol 2010: 10: 813-25.
    • (2010) Nat Rev Immunol , vol.10 , pp. 813-825
    • Turley, S.J.1    Fletcher, A.L.2    Elpek, K.G.3
  • 115
    • 77951074210 scopus 로고    scopus 로고
    • Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
    • Fletcher AL, Lukacs-Kornek V, Reynoso ED et al. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med 2010: 207: 689-97.
    • (2010) J Exp Med , vol.207 , pp. 689-697
    • Fletcher, A.L.1    Lukacs-Kornek, V.2    Reynoso, E.D.3
  • 116
    • 77951069509 scopus 로고    scopus 로고
    • Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
    • Cohen JN, Guidi CJ, Tewalt EF et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med 2010: 207: 681-8.
    • (2010) J Exp Med , vol.207 , pp. 681-688
    • Cohen, J.N.1    Guidi, C.J.2    Tewalt, E.F.3
  • 117
    • 49449093723 scopus 로고    scopus 로고
    • Deletional tolerance mediated by extrathymic Aire-expressing cells
    • Gardner JM, Devoss JJ, Friedman RS et al. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008: 321: 843-7.
    • (2008) Science , vol.321 , pp. 843-847
    • Gardner, J.M.1    Devoss, J.J.2    Friedman, R.S.3
  • 118
    • 33846546257 scopus 로고    scopus 로고
    • Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
    • Lee JW, Epardaud M, Sun J et al. Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self. Nat Immunol 2007: 8: 181-90.
    • (2007) Nat Immunol , vol.8 , pp. 181-190
    • Lee, J.W.1    Epardaud, M.2    Sun, J.3
  • 119
    • 84859926294 scopus 로고    scopus 로고
    • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
    • Malhotra D, Fletcher AL, Astarita J et al. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol 2012: 13: 499-510.
    • (2012) Nat Immunol , vol.13 , pp. 499-510
    • Malhotra, D.1    Fletcher, A.L.2    Astarita, J.3
  • 120
    • 34848852256 scopus 로고    scopus 로고
    • Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
    • Mueller SN, Matloubian M, Clemens DM et al. Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci U S A 2007: 104: 15430-5.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15430-15435
    • Mueller, S.N.1    Matloubian, M.2    Clemens, D.M.3
  • 121
    • 84874062931 scopus 로고    scopus 로고
    • A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo
    • Onder L, Scandella E, Chai Q et al. A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo. Front Immunol 2011: 2: 50.
    • (2011) Front Immunol , vol.2 , pp. 50
    • Onder, L.1    Scandella, E.2    Chai, Q.3


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