Liver sinusoidal endothelial cells are insufficient to activate T cells

Journal of Immunology

Volumn 173, Issue 1, 2004, Pages 230-235

  Katz, Steven C ^a   Pillarisetty, Venu G ^a   Bleier, Joshua I ^a   Shah, Alaap B ^a   DeMatteo, Ronald P ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; ANTIGEN; B7 ANTIGEN; CD31 ANTIGEN; CD45 ANTIGEN; CD86 ANTIGEN; COLLAGENASE; FC RECEPTOR; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR; VON WILLEBRAND FACTOR;

ADOLESCENT; ALLOIMMUNITY; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL FRACTIONATION; CELL FUNCTION; CONTROLLED STUDY; COSTIMULATION; DENDRITIC CELL; DENSITY GRADIENT CENTRIFUGATION; ENDOTHELIUM CELL; FLOW CYTOMETRY; IMMUNOMAGNETIC SEPARATION; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; LIVER SINUSOID; LIVER SINUSOID ENDOTHELIUM CELL; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

EID: 2942741153     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.1.230     Document Type: Article

References (33)

1. Cantor, H. M., and A. E. Dumont. 1967. Hepatic suppression of sensitization to antigen absorbed into the portal system. Nature 215:744.
2. Kamei, T., M. P. Callery, and M. W. Flye. 1990. Pretransplant portal venous administration of donor antigen and portal venous allograft drainage synergistically prolong rat cardiac allograft survival. Surgery 108:415.
3. Calne, R. Y., R. A. Sells, J. R. Pena, D. R. Davis, P. R. Millard, B. M. Herbertson, R. M. Binns, and D. A. Davies. 1969. Induction of immunological tolerance by porcine liver allografts. Nature 223:472.
4. Gershwin M. E., J. M. Vierling, M. P. Manns. 2003. Liver Immunology. Hanley & Belfus, Philadelphia.
5. Smedsrod, B., H. Pertoft, S. Gustafson, and T. C. Laurent. 1990. Scavenger functions of the liver endothelial cell. Biochem. J. 266:313.
6. Knolle, P. A., and A. Limmer. 2001. Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells. Trends Immunol. 22:432.
7. + T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells. Gastroenterology 116:1428.
8. + T cells results in antigen-specific T-cell tolerance. Nat. Med. 6:1348.
9. Lohse, A. W., P. A. Knolle, K. Bilo, A. Uhrig, C. Waldmann, M. Ibe, E. Schmitt, G. Gerken, and K. H. Meyer Zum Buschenfelde. 1996. Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells. Gastroenterology 110:1175.
10. Limmer, A., and P. A. Knolle. 2001. Liver sinusoidal endothelial cells: a new type of organ-resident antigen-presenting cell. Arch. Immunol. Ther. Exp. 49(Suppl. 1):S7.
11. Pitas, R. E., J. Boyles, R. W. Mahley, and D. M. Bissell. 1985. Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells. J. Cell Biol. 100:103.
12. Rubinstein, D., A. K. Roska, and P. E. Lipsky. 1986. Liver sinusoidal lining cells express class II major histocompatibility antigens but are poor stimulators of fresh allogeneic T lymphocytes. J. Immunol. 137:1803.
13. Knolle, P. A., T. Germann, U. Treichel, A. Uhrig, E. Schmitt, S. Hegenbarth, A. W. Lohse, and G. Gerken. 1999. Endotoxin down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells. J. Immunol. 162:1401.
14. McCourt, P. A., B. H. Smedsrod, J. Melkko, and S. Johansson. 1999. Characterization of a hyaluronan receptor on rat sinusoidal liver endothelial cells and its functional relationship to scavenger receptors. Hepatology 30:1276.
15. Thomson, A. W., P. J. O'Connell. R. J. Steptoe, and L. Lu. 2002. Immunobiology of liver dendrific cells. Immunol. Cell Biol. 80:65.
16. Lu, L., J. Woo, Y. Li, A. S. Rao, and A. W. Thomson. 1995. Isolation of dendritic leukocytes from mouse liver. Adv. Exp. Med. Biol. 378:543.
17. Lau, A. H., and A. W. Thomson. 2003. Dendritic cells and immune regulation in the liver. Gut 52:307.
18. Pillarisetty, V. G., A. B. Shah, G. Miller, J. I. Bleier, and R. P. DeMatteo. 2004. Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition. J. Immunol. 172:1009.
19. Pillarisetty, V. G., G. Miller, A. B. Shah, and R. P. DeMatteo. 2003. GM-CSF expands dendritic cells and their progenitors in mouse liver. Hepatology 37:641.
20. Barnden, M. J., J. Allison, W. R. Heath, and Carbone, F. R. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76:34.
21. Jackson, D. E. 2003. The unfolding tale of PECAM-1. FEBS Lett. 540:7.
22. Hannah, M. J., R. Williams, J. Kaur, L. J. Hewlett, and D. F. Cutler. 2002. Biogenesis of Weibel-Palade bodies. Semin. Cell Dev. Biol. 13:313.
23. Do, H., J. F. Healey, E. K. Waller, and P. Lollar. 1999. Expression of factor VIII by murine liver sinusoidal endothelial cells. J. Biol. Chem. 274:19587.
24. Muro, H., H. Shirasawa, Y. Takahashi, M. Maeda, and S. Nakamura. 1988. Localization of Fc receptors on liver sinusoidal endothelium: a histological study by electron microscopy. Acta Pathol. Jpn. 38:291.
25. Knolle, P. A., A. Uhrig, S. Hegenbarth, E. Loser, E. Schmitt, G. Gerken, and A. W. Lohse. 1998. IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules. Clin. Exp. Immunol. 114:427.
26. Braet, F., and E. Wisse. 2002. Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp. Hepatol. 1:1.
27. Dini, L., and E. C. Carla. 1998. Hepatic sinusoidal endothelium heterogeneity with respect to the recognition of apoptotic cells. Exp. Cell Res. 240:388.
28. Srisatjaluk, R., G. J. Kotwal, L. A. Hunt, and D. E. Justus. 2002. Modulation of γ interferon-induced major bistocompatibility complex class II gene expression by Porphyromonas gingivalis membrane vesicles. Infect. Immun. 70:1185.
29. + T cells: a mechanism of immunoregulation? J. Immunol. 165:4182.
30. + T lymphocytes in a B7-dependent fashion. J. Immunol. 169:6154.
31. Knolle, P. A., G. Gerken, E. Loser, H. P. Dienes, F. Gantner, G. Tiegs, K. H. Meyer zum Buschenfelde, and A. W. Lohse. 1996. Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice. Hepatology 24:824.
32. Lian, Z. X., T. Okada, X. S. He, H. Kita, Y. J. Liu, A. A. Ansari, K. Kikuchi, S. Ikehara, and M. E. Gershwin. 2003. Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations. J. Immunol. 170:2323.
33. + T cells by the normal liver. J. Immunol. 163:3202.