메뉴 건너뛰기




Volumn 23, Issue 6, 2013, Pages 402-411

Sildenafil citrate attenuates the deleterious effects of elevated ammonia

Author keywords

Antioxidants; CGMP; Hyperammonemia; Phosphodiesterase; Sildenafil

Indexed keywords

ALKALINE PHOSPHATASE; AMMONIUM CHLORIDE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; NITRIC OXIDE; SILDENAFIL; SUPEROXIDE DISMUTASE;

EID: 84879647752     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2013.770109     Document Type: Article
Times cited : (10)

References (87)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. (1984). Catalase in vitro. Methods Enzymol 105:121-26.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 0026178026 scopus 로고
    • Studies on mechanism of haloacetonitrile induced gastrointestinal toxicity, interaction of dibromoacetonitrile with glutathione as glutathiones- transferase in rats
    • Ahmed AE, Gamal IH, Loh J, Abdel-Rahman SZ. (1991). Studies on mechanism of haloacetonitrile induced gastrointestinal toxicity, interaction of dibromoacetonitrile with glutathione as glutathiones- transferase in rats. J Biol Toxicol 612:115-21.
    • (1991) J Biol Toxicol , vol.612 , pp. 115-121
    • Ahmed, A.E.1    Gamal, I.H.2    Loh, J.3    Abdel-Rahman, S.Z.4
  • 3
    • 84856254553 scopus 로고    scopus 로고
    • Ammonia toxicity in the central nervous system
    • Lajtha A, Johnson A, Dianna A, eds Chapter 12. Berlin, Heidelberg: Springer-Verlag
    • Albrecht J. (2007). Ammonia toxicity in the central nervous system. In: Lajtha A, Johnson A, Dianna A, eds. Handbook of neurochemistry and molecular neurobiology. Chapter 12. Berlin, Heidelberg: Springer- Verlag, 261-76.
    • (2007) Handbook of Neurochemistry and Molecular Neurobiology , pp. 261-276
    • Albrecht, J.1
  • 4
    • 0003229895 scopus 로고
    • Reactive oxygen in the aetiology and complications of diabetes
    • Ioannides C, Flatt PR, eds Hertfortshive: Ellis Horwood limited
    • Baynes JW. (1995). Reactive oxygen in the aetiology and complications of diabetes. In: Ioannides C, Flatt PR, eds. Drug diet and disease. Vol. 2. Mechanistic approach to diabetes. Hertfortshive: Ellis Horwood limited, 230-1.
    • (1995) Drug Diet and Disease. Vol. 2. Mechanistic Approach to Diabetes , pp. 230-231
    • Baynes, J.W.1
  • 5
    • 0036188199 scopus 로고    scopus 로고
    • A flavonoid-rich diet increases nitric oxide production in rat aorta
    • Benito S, Lopez D, Sa'iz MP, et al. (2002). A flavonoid-rich diet increases nitric oxide production in rat aorta. Br J Pharmacol 135:910-16.
    • (2002) Br J Pharmacol , vol.135 , pp. 910-916
    • Benito, S.1    Lopez, D.2    Sa'Iz, M.P.3
  • 6
    • 0028470598 scopus 로고
    • Vitamin E: Molecular and biological function
    • Burton GW. (1994). Vitamin E: molecular and biological function. Proc Nutr Soc 53:251-62.
    • (1994) Proc Nutr Soc , vol.53 , pp. 251-262
    • Burton, G.W.1
  • 7
    • 80855144594 scopus 로고    scopus 로고
    • Sildenafil treatment attenuates lung and kidney injury due to overproduction of oxidant activity in a rat model of sepsis: A biochemical and histopathological study
    • Cadirci E, Halici Z, Odabasoglu F, et al. (2011). Sildenafil treatment attenuates lung and kidney injury due to overproduction of oxidant activity in a rat model of sepsis: a biochemical and histopathological study. Clin Exp Immunol 166:374-84.
    • (2011) Clin Exp Immunol , vol.166 , pp. 374-384
    • Cadirci, E.1    Halici, Z.2    Odabasoglu, F.3
  • 8
    • 53749090841 scopus 로고    scopus 로고
    • Role of caspases, calpain and cdk5 in ammonia-induced cell death in developing brain cells
    • Cagnon L, Braissant O. (2008). Role of caspases, calpain and cdk5 in ammonia-induced cell death in developing brain cells. Neurobiol Dis 32:281-92.
    • (2008) Neurobiol Dis , vol.32 , pp. 281-292
    • Cagnon, L.1    Braissant, O.2
  • 9
    • 0027405261 scopus 로고
    • Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts
    • Carr TP, Andresen CJ, Rudel LL. (1993). Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 26:39-42.
    • (1993) Clin Biochem , vol.26 , pp. 39-42
    • Carr, T.P.1    Andresen, C.J.2    Rudel, L.L.3
  • 10
    • 33747190865 scopus 로고    scopus 로고
    • Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment
    • Chepkova AN, Sergeeva OA, Haas HL. (2006). Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment. Neurobiol Dis 23:512-21.
    • (2006) Neurobiol Dis , vol.23 , pp. 512-521
    • Chepkova, A.N.1    Sergeeva, O.A.2    Haas, H.L.3
  • 11
    • 0023277545 scopus 로고
    • Single step method for RNA isolation by the acid guanidinum thiocyanate phenol chloroform methods
    • Chomkczynski P, Sacchi N. (1987). Single step method for RNA isolation by the acid guanidinum thiocyanate phenol chloroform methods. Anal Biochem 162:156-60.
    • (1987) Anal Biochem , vol.162 , pp. 156-160
    • Chomkczynski, P.1    Sacchi, N.2
  • 12
    • 0017339321 scopus 로고
    • Photometric determination of total protein in lipemic sera
    • Chromy V, Fischer J. (1977). Photometric determination of total protein in lipemic sera. Clin Chem 23:754-6.
    • (1977) Clin Chem , vol.23 , pp. 754-756
    • Chromy, V.1    Fischer, J.2
  • 13
    • 0032323162 scopus 로고    scopus 로고
    • Sildenafil, a type-5 CGMP phosphodiesterase inhibitor, specifically amplifies endogenous cGMP-dependent relaxation in rabbit corpus cavernosum smooth muscle in vitro
    • Chuang AT, Strauss JD, Murphy RA, Steers WD. (1998). Sildenafil, a type-5 CGMP phosphodiesterase inhibitor, specifically amplifies endogenous cGMP-dependent relaxation in rabbit corpus cavernosum smooth muscle in vitro. J Urol 160:257-61.
    • (1998) J Urol , vol.160 , pp. 257-261
    • Chuang, A.T.1    Strauss, J.D.2    Murphy, R.A.3    Steers, W.D.4
  • 14
    • 0036723924 scopus 로고    scopus 로고
    • Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: Implication for a survival role of nitric oxide
    • Ciani E, Guidi S, Bartesaghi R, Contestabile A. (2002). Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide. J Neurochem 82:1282-9.
    • (2002) J Neurochem , vol.82 , pp. 1282-1289
    • Ciani, E.1    Guidi, S.2    Bartesaghi, R.3    Contestabile, A.4
  • 15
    • 0036829813 scopus 로고    scopus 로고
    • Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients
    • Corbala'n R, Chatauret N, Behrends S, et al. (2002). Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients. Hepatology 36:1155-62.
    • (2002) Hepatology , vol.36 , pp. 1155-1162
    • Corbala'N, R.1    Chatauret, N.2    Behrends, S.3
  • 16
    • 0035995831 scopus 로고    scopus 로고
    • Effects of ornithine alpha ketoglutarate on circulatory antioxidants and lipid peroxidation products in ammonium acetate treated rats
    • Dakshayani KB, Velvizhi S, Subramanian P. (2002). Effects of ornithine alpha ketoglutarate on circulatory antioxidants and lipid peroxidation products in ammonium acetate treated rats. Ann Nutr Metab 46:93-6.
    • (2002) Ann Nutr Metab , vol.46 , pp. 93-96
    • Dakshayani, K.B.1    Velvizhi, S.2    Subramanian, P.3
  • 19
    • 67650924294 scopus 로고    scopus 로고
    • Sildenafil decreased cardiac cell apoptosis in diabetic mice: Reduction of oxidative stress as a possible mechanism
    • Ebrahimi F, Shafaroodi H, Asadi S, et al. (2009). Sildenafil decreased cardiac cell apoptosis in diabetic mice: reduction of oxidative stress as a possible mechanism. Can J Physiol Pharmacol 87:556-64.
    • (2009) Can J Physiol Pharmacol , vol.87 , pp. 556-564
    • Ebrahimi, F.1    Shafaroodi, H.2    Asadi, S.3
  • 20
    • 35848957503 scopus 로고    scopus 로고
    • Involvement of alpha-receptors and potassium channels in the mechanism of action of sildenafil citrate
    • El-Metwally MA, Sharabi FM, Daabees TT, et al. (2007). Involvement of alpha-receptors and potassium channels in the mechanism of action of sildenafil citrate. Int J Impot Res 19:551-7.
    • (2007) Int J Impot Res , vol.19 , pp. 551-557
    • El-Metwally, M.A.1    Sharabi, F.M.2    Daabees, T.T.3
  • 21
    • 13844296393 scopus 로고    scopus 로고
    • Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain
    • Erceg S, Monfort P, Hernandez-Viadel M, et al. (2005a). Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain. Brain Res 1036:115-21.
    • (2005) Brain Res , vol.1036 , pp. 115-121
    • Erceg, S.1    Monfort, P.2    Hernandez-Viadel, M.3
  • 22
    • 12844262177 scopus 로고    scopus 로고
    • Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts
    • Erceg S, Monfort P, Herna'ndez-Viadel M, et al. (2005b). Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts. Hepatology 41:299-306.
    • (2005) Hepatology , vol.41 , pp. 299-306
    • Erceg, S.1    Monfort, P.2    Herna'Ndez-Viadel, M.3
  • 23
    • 84859891578 scopus 로고    scopus 로고
    • Effect of leaves on serum lipids in ammonium chloride induced experimental hyperammonemic rats Pongamia pinnata
    • Essa MM, Ali AA, Waly MI, et al. (2010). Effect of leaves on serum lipids in ammonium chloride induced experimental hyperammonemic rats Pongamia pinnata. Int J Biol Med Res 1:71-3.
    • (2010) Int J Biol Med Res , vol.1 , pp. 71-73
    • Essa, M.M.1    Ali, A.A.2    Waly, M.I.3
  • 24
    • 33646515070 scopus 로고    scopus 로고
    • Pongamia pinnata modulates oxidantantioxidant imbalance during hyperammonemic rats
    • Essa MM, Subramanian P. (2006). Pongamia pinnata modulates oxidantantioxidant imbalance during hyperammonemic rats. Fundam Clin Pharmacol 20:299-303.
    • (2006) Fundam Clin Pharmacol , vol.20 , pp. 299-303
    • Essa, M.M.1    Subramanian, P.2
  • 25
    • 85116952132 scopus 로고    scopus 로고
    • Protective influence of Pongamia pinnata (Karanja) on blood ammonia and urea levels in ammonium chloride induced hyperammonemia
    • Essa MM, Subramanian P, Suthakar G, et al. (2005). Protective influence of Pongamia pinnata (Karanja) on blood ammonia and urea levels in ammonium chloride induced hyperammonemia. J Appl Biomed 3263:13-24.
    • (2005) J Appl Biomed , vol.3263 , pp. 13-24
    • Essa, M.M.1    Subramanian, P.2    Suthakar, G.3
  • 26
    • 82855172055 scopus 로고    scopus 로고
    • Effect of sildenafil citrate (Viagra-) on trace element concentration in serum and brain of rats
    • Fayed AH, Gad SB. (2011). Effect of sildenafil citrate (Viagra-) on trace element concentration in serum and brain of rats. J Trace Elem Med Biol 25:236-8.
    • (2011) J Trace Elem Med Biol , vol.25 , pp. 236-238
    • Fayed, A.H.1    Gad, S.B.2
  • 27
    • 33846192274 scopus 로고    scopus 로고
    • Contribution of altered signal transduction associated to glutamate receptors in brain to the neurological alterations of hepatic encephalopathy
    • Felipo V. (2006). Contribution of altered signal transduction associated to glutamate receptors in brain to the neurological alterations of hepatic encephalopathy. World J Gastroenterol 12:7737-43.
    • (2006) World J Gastroenterol , vol.12 , pp. 7737-7743
    • Felipo, V.1
  • 28
    • 24144449540 scopus 로고    scopus 로고
    • Phosphodiestrase 5 inhibitor, zaprinast, selectively increases cerebral blood flow in the ischemic penumbra in the rat brain
    • Feng G, Masao S, Hideaki N. (2005). Phosphodiestrase 5 inhibitor, zaprinast, selectively increases cerebral blood flow in the ischemic penumbra in the rat brain. Neurol Res 27:638-43.
    • (2005) Neurol Res , vol.27 , pp. 638-643
    • Feng, G.1    Masao, S.2    Hideaki, N.3
  • 29
    • 0019949179 scopus 로고
    • Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide
    • Fossati P, Prencipe L. (1982). Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 28:2077-80.
    • (1982) Clin Chem , vol.28 , pp. 2077-2080
    • Fossati, P.1    Prencipe, L.2
  • 30
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 31
    • 0034838812 scopus 로고    scopus 로고
    • Allosteric sites of phosphodiestrase-5 (PDE-5)
    • Gopal VK, Francis SH, Corbin JD. (2001). Allosteric sites of phosphodiestrase-5 (PDE-5). Eur J Biochem 268:3304-12.
    • (2001) Eur J Biochem , vol.268 , pp. 3304-3312
    • Gopal, V.K.1    Francis, S.H.2    Corbin, J.D.3
  • 32
    • 0018075429 scopus 로고
    • Optimal conditions for the estimation of ammonium by the Berthelot reaction
    • Gordon SA, Fleck A, Bell J. (1978). Optimal conditions for the estimation of ammonium by the Berthelot reaction. Ann Clin Biochem 15:270-5.
    • (1978) Ann Clin Biochem , vol.15 , pp. 270-275
    • Gordon, S.A.1    Fleck, A.2    Bell, J.3
  • 33
    • 0018362196 scopus 로고
    • Effect of reagent pH on determination of HDL cholesterol by precipitation with sodium phosphotungestate-magnesium
    • Grove TH. (1979). Effect of reagent pH on determination of HDL cholesterol by precipitation with sodium phosphotungestate-magnesium. Clin Chem 25:560-4.
    • (1979) Clin Chem , vol.25 , pp. 560-564
    • Grove, T.H.1
  • 34
    • 35348901927 scopus 로고    scopus 로고
    • The role of PDE5-inhibitors in cardiopulmonary disorders: From basic evidence to clinical development
    • Guazzi M, Samaja M. (2007). The role of PDE5-inhibitors in cardiopulmonary disorders: from basic evidence to clinical development. Curr Med Chem 14:1893-910.
    • (2007) Curr Med Chem , vol.14 , pp. 1893-1910
    • Guazzi, M.1    Samaja, M.2
  • 35
    • 79151472576 scopus 로고    scopus 로고
    • Clinical practice: The management of hyperammonemia
    • Haberle J. (2011). Clinical practice: the management of hyperammonemia. Eur J Pediatr 170:21-34.
    • (2011) Eur J Pediatr , vol.170 , pp. 21-34
    • Haberle, J.1
  • 36
    • 48549084904 scopus 로고    scopus 로고
    • Assessing the physiological concentrations and targets of nitric oxide in brain tissue
    • Hall CN, Attwell D. (2008). Assessing the physiological concentrations and targets of nitric oxide in brain tissue. J Physiol 586:3597-615.
    • (2008) J Physiol , vol.586 , pp. 3597-3615
    • Hall, C.N.1    Attwell, D.2
  • 37
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell B. (2001). Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18:685-716.
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 38
    • 4143050687 scopus 로고    scopus 로고
    • Enzymes
    • Burits CA, Ashwood ER, eds 5th ed. Philadelphia: W.B. Saunders Company
    • Henderson AR, Moss DW. (2001). Enzymes. In: Burits CA, Ashwood ER, eds. Tietz fundamentals of clinical chemistry. 5th ed. Philadelphia: W.B. Saunders Company, 352.
    • (2001) Tietz Fundamentals of Clinical Chemistry , vol.352
    • Henderson, A.R.1    Moss, D.W.2
  • 39
    • 0035976036 scopus 로고    scopus 로고
    • Effect of taurine on toxicity of cadmium in rats
    • Hwang DF, Wang LC. (2001). Effect of taurine on toxicity of cadmium in rats. Toxicology 167:173-80.
    • (2001) Toxicology , vol.167 , pp. 173-180
    • Hwang, D.F.1    Wang, L.C.2
  • 41
    • 17044415276 scopus 로고    scopus 로고
    • Safety and efficacy of sildenafil therapy in children with pulmonary hypertension
    • Karatza AA, Bush A, Magee AG. (2005). Safety and efficacy of sildenafil therapy in children with pulmonary hypertension. Int J Cardiol 100:267-73.
    • (2005) Int J Cardiol , vol.100 , pp. 267-273
    • Karatza, A.A.1    Bush, A.2    Magee, A.G.3
  • 42
    • 33746379603 scopus 로고    scopus 로고
    • JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
    • Kim BJ, Ryu SW, Song BJ. (2006). JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J Biol Chem 281:21256-65.
    • (2006) J Biol Chem , vol.281 , pp. 21256-21265
    • Kim, B.J.1    Ryu, S.W.2    Song, B.J.3
  • 43
    • 0030051387 scopus 로고    scopus 로고
    • Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes
    • Kojda G, Kottenbery K, Nix P, et al. (1996). Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes. Circ Res 78:91-101.
    • (1996) Circ Res , vol.78 , pp. 91-101
    • Kojda, G.1    Kottenbery, K.2    Nix, P.3
  • 44
    • 3142566659 scopus 로고    scopus 로고
    • Nitric oxide synthesis in the kidney: Isoforms, biosynthesis, and functions in health
    • Kone BC. (2004). Nitric oxide synthesis in the kidney: isoforms, biosynthesis, and functions in health. Semin Nephrol 24:299-315.
    • (2004) Semin Nephrol , vol.24 , pp. 299-315
    • Kone, B.C.1
  • 45
    • 0031460097 scopus 로고    scopus 로고
    • Superoxide production and antioxidant enzymes in ammonia intoxication in rats
    • Kosenko E, Kaminsky A, Valencia M, et al. (1997). Superoxide production and antioxidant enzymes in ammonia intoxication in rats. Free Radic Res 27:637-44.
    • (1997) Free Radic Res , vol.27 , pp. 637-644
    • Kosenko, E.1    Kaminsky, A.2    Valencia, M.3
  • 46
    • 0036988607 scopus 로고    scopus 로고
    • Cerebral blood flow in hyperammonemia: Heterogeneity and starling forces in capillaries
    • Larsen FS. (2002). Cerebral blood flow in hyperammonemia: heterogeneity and starling forces in capillaries. Metab Brain Dis 17:229-35.
    • (2002) Metab Brain Dis , vol.17 , pp. 229-235
    • Larsen, F.S.1
  • 47
    • 1642543934 scopus 로고    scopus 로고
    • Evaluation of the antiperoxidative effects of melatonin in ammonium acetate-treated Wistar rats
    • Lena PJ, Subramanian P. (2003). Evaluation of the antiperoxidative effects of melatonin in ammonium acetate-treated Wistar rats. Pol J Pharmacol 55:1031-6.
    • (2003) Pol J Pharmacol , vol.55 , pp. 1031-1036
    • Lena, P.J.1    Subramanian, P.2
  • 48
    • 4143092514 scopus 로고    scopus 로고
    • Effects of melatonin on the levels of antioxidants and lipid peroxidation products in rats treated with ammonium acetate
    • Lena PJ, Subramanian P. (2004). Effects of melatonin on the levels of antioxidants and lipid peroxidation products in rats treated with ammonium acetate. Pharmazie 59:636-9.
    • (2004) Pharmazie , vol.59 , pp. 636-639
    • Lena, P.J.1    Subramanian, P.2
  • 49
    • 33748743368 scopus 로고    scopus 로고
    • Expression, distribution and regulation of phosphodiestrase 5
    • Lin CS, Lin G, Xin ZC, Lue TF. (2006). Expression, distribution and regulation of phosphodiestrase 5. Curr Pharm Des 12:3439-57.
    • (2006) Curr Pharm des , vol.12 , pp. 3439-3457
    • Lin, C.S.1    Lin, G.2    Xin, Z.C.3    Lue, T.F.4
  • 50
    • 0033832073 scopus 로고    scopus 로고
    • Guanylyl cyclases and signaling by cyclic GMP
    • Lucas KA, Pitari GM, Kazerounian S, et al. (2000). Guanylyl cyclases and signaling by cyclic GMP. Pharmacol Rev 53:375-414.
    • (2000) Pharmacol Rev , vol.53 , pp. 375-414
    • Lucas, K.A.1    Pitari, G.M.2    Kazerounian, S.3
  • 51
    • 84861189108 scopus 로고    scopus 로고
    • Influence of rutin on biochemical alterations in hyperammonemia in rats
    • Mahmoud AM. (2012). Influence of rutin on biochemical alterations in hyperammonemia in rats. Exp Toxicol Pathol 64:783-9.
    • (2012) Exp Toxicol Pathol , vol.64 , pp. 783-789
    • Mahmoud, A.M.1
  • 52
    • 27444441925 scopus 로고    scopus 로고
    • Hyperammonemia is associated with an increase in inhibitory neurotransmission as a consequence of two factors
    • Majeed KI. (2005). Hyperammonemia is associated with an increase in inhibitory neurotransmission as a consequence of two factors. E Med J 2:12-15.
    • (2005) E Med J , vol.2 , pp. 12-15
    • Majeed, K.I.1
  • 53
    • 33748908152 scopus 로고    scopus 로고
    • Removal of ammonium from aqueous solutions with volcanic tuff
    • Maranón E, Ulmanub M, Fernándeza Y, et al. (1996). Removal of ammonium from aqueous solutions with volcanic tuff. J Hazard Mater 137:1402-9.
    • (1996) J Hazard Mater , vol.137 , pp. 1402-1409
    • Maranón, E.1    Ulmanub, M.2    Fernándeza, Y.3
  • 55
    • 0035025079 scopus 로고    scopus 로고
    • Hyperammonemia in urea cycle disorders: Role of the nephrologist
    • Mathias RS, Kostiner D, Packman S. (2001). Hyperammonemia in urea cycle disorders: role of the nephrologist. Am J Kidney Dis 37:1069-80.
    • (2001) Am J Kidney Dis , vol.37 , pp. 1069-1080
    • Mathias, R.S.1    Kostiner, D.2    Packman, S.3
  • 56
    • 0018175297 scopus 로고
    • The 4- hydroxybenzoate/4-aminophenazone chromogenic system used in the enzymatic determination of serum cholesterol
    • Meiattini F, Prencipe L, Bardelli F, Giannini G. (1978). The 4- hydroxybenzoate/4-aminophenazone chromogenic system used in the enzymatic determination of serum cholesterol. Clin Chem 24:2161-5.
    • (1978) Clin Chem , vol.24 , pp. 2161-2165
    • Meiattini, F.1    Prencipe, L.2    Bardelli, F.3    Giannini, G.4
  • 57
    • 0029033537 scopus 로고
    • Nitrite and nitrate determination in plasma: A critical evaluation
    • Moshage H, Kok B, Heuzenga JR, Jansen PL. (1995). Nitrite and nitrate determination in plasma: a critical evaluation. Clin Chem 41:892-6.
    • (1995) Clin Chem , vol.41 , pp. 892-896
    • Moshage, H.1    Kok, B.2    Heuzenga, J.R.3    Jansen, P.L.4
  • 58
    • 0024357989 scopus 로고
    • Expression cloning of the murine interferon gamma receptor cDNA
    • Munro S, Maniatis T. (1989). Expression cloning of the murine interferon gamma receptor cDNA. Proc Natl Acad Sci USA 86:9248-52.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9248-9252
    • Munro, S.1    Maniatis, T.2
  • 59
    • 0035888288 scopus 로고    scopus 로고
    • Ammonia induced production of free radicals in primary cultures of rat astrocytes
    • Murthy CR, Rama Rao KV, Bai G, Norenburg MD. (2001). Ammonia induced production of free radicals in primary cultures of rat astrocytes. J Neurosci Res 66:282-8.
    • (2001) J Neurosci Res , vol.66 , pp. 282-288
    • Murthy, C.R.1    Rama Rao, K.V.2    Bai, G.3    Norenburg, M.D.4
  • 61
    • 0015530358 scopus 로고
    • The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen
    • Nishikimi M, Roa NA, Yogi K. (1972). The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem Bioph Res Common 46:849-54.
    • (1972) Biochem Bioph Res Common , vol.46 , pp. 849-854
    • Nishikimi, M.1    Roa, N.A.2    Yogi, K.3
  • 62
    • 0036350615 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits
    • Ockaili R, Salloum F, Hawkins J, Kukreja RC. (2002). Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits. Am J Physiol Heart Circ Physiol 283:H1263-9.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Ockaili, R.1    Salloum, F.2    Hawkins, J.3    Kukreja, R.C.4
  • 63
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 64
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158-69.
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 65
    • 83155192220 scopus 로고    scopus 로고
    • Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain
    • Puerta E, Barros-Minones L, Hervias I, et al. (2012). Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain. J Neurosci Res 90:518-28.
    • (2012) J Neurosci Res , vol.90 , pp. 518-528
    • Puerta, E.1    Barros-Minones, L.2    Hervias, I.3
  • 66
    • 1442351151 scopus 로고    scopus 로고
    • Preliminary evaluation of antihepatotoxic activity of Kamilari, a poly herbal formulation
    • Rajesh MG, Latha MS. (2004). Preliminary evaluation of antihepatotoxic activity of Kamilari, a poly herbal formulation. J Ethnopharmacol 91:99-104.
    • (2004) J Ethnopharmacol , vol.91 , pp. 99-104
    • Rajesh, M.G.1    Latha, M.S.2
  • 67
    • 12344317728 scopus 로고    scopus 로고
    • Bile duct ligation plus hyperammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patients
    • Rodrigo R, Jover R, Candela A, et al. (2005). Bile duct ligation plus hyperammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patients. Neuroscience 130:435-43.
    • (2005) Neuroscience , vol.130 , pp. 435-443
    • Rodrigo, R.1    Jover, R.2    Candela, A.3
  • 68
    • 0027447930 scopus 로고
    • Multicenter evaluation of Iso-ALP test kit for measurement of bone alkaline phosphatase activity in serum and plasma
    • Rosalki SB, Foo AY, Burlina A, et al. (1993). Multicenter evaluation of Iso-ALP test kit for measurement of bone alkaline phosphatase activity in serum and plasma. Clin Chem 39:648-52.
    • (1993) Clin Chem , vol.39 , pp. 648-652
    • Rosalki, S.B.1    Foo, A.Y.2    Burlina, A.3
  • 70
    • 67650500252 scopus 로고    scopus 로고
    • Lipid levels in female patients with affective disorders
    • Sagud M, Mihaljevic-Peles A, Pivac N, et al. (2009). Lipid levels in female patients with affective disorders. Psychiatry Res 168:218-21.
    • (2009) Psychiatry Res , vol.168 , pp. 218-221
    • Sagud, M.1    Mihaljevic-Peles, A.2    Pivac, N.3
  • 71
    • 0034722592 scopus 로고    scopus 로고
    • A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze
    • Smith S, Dringenberg HC, Bennett BM, et al. (2000). A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze. Neuro Rep 11:3883-6.
    • (2000) Neuro Rep , vol.11 , pp. 3883-3886
    • Smith, S.1    Dringenberg, H.C.2    Bennett, B.M.3
  • 72
    • 0024603895 scopus 로고
    • Modifications of low density lipoproteins that increase its atherogenicity
    • Steinberg D, Parathasarathy S, Carew TE, et al. (1989). Modifications of low density lipoproteins that increase its atherogenicity. N Engl J Med 320:915-18.
    • (1989) N Engl J Med , vol.320 , pp. 915-918
    • Steinberg, D.1    Parathasarathy, S.2    Carew, T.E.3
  • 73
    • 67349208238 scopus 로고    scopus 로고
    • Morin a flavonoid exerts antioxidant potential in chronic hyperammonemic rats: A biochemical and histopathological study
    • Subash S, Subramanian P. (2009). Morin a flavonoid exerts antioxidant potential in chronic hyperammonemic rats: a biochemical and histopathological study. Mol Cell Biochem 327:153-61.
    • (2009) Mol Cell Biochem , vol.327 , pp. 153-161
    • Subash, S.1    Subramanian, P.2
  • 74
    • 84859911325 scopus 로고    scopus 로고
    • Impact of morin (a bioflavonoid) on ammonium chloride-mediated oxidative damage in rat kidney
    • Subash S, Subramanian P. (2011). Impact of morin (a bioflavonoid) on ammonium chloride-mediated oxidative damage in rat kidney. Int J Nutr Pharmacol Neurol Dis 1:174-8.
    • (2011) Int J Nutr Pharmacol Neurol Dis , vol.1 , pp. 174-178
    • Subash, S.1    Subramanian, P.2
  • 75
    • 84859893746 scopus 로고    scopus 로고
    • Protective effect of morin on lipid peroxidation and lipid profile in ammonium chloride-induced hyperammonemic rats
    • Subash S, Subramanian P. (2012). Protective effect of morin on lipid peroxidation and lipid profile in ammonium chloride-induced hyperammonemic rats. Asian Pac J Trop Dis 2:103-6.
    • (2012) Asian Pac J Trop Dis , vol.2 , pp. 103-106
    • Subash, S.1    Subramanian, P.2
  • 76
    • 33644836737 scopus 로고    scopus 로고
    • Nitric oxide, a biological double-faced janus - Is this good or bad?
    • Thippeswamy T, McKay JS, Quinn JP, Morris R. (2006). Nitric oxide, a biological double-faced janus - is this good or bad? Histol Histopathol 21:445-58.
    • (2006) Histol Histopathol , vol.21 , pp. 445-458
    • Thippeswamy, T.1    McKay, J.S.2    Quinn, J.P.3    Morris, R.4
  • 77
    • 0036793092 scopus 로고    scopus 로고
    • Protective influences of alpha-keto glutarate on lipid peroxidation and antioxidant status ammonium acetate rats
    • Velvizhi S, Dakshayani KB, Subramanian P. (2002). Protective influences of alpha-keto glutarate on lipid peroxidation and antioxidant status ammonium acetate rats. Ind J Exp Biol 40:1183-6.
    • (2002) Ind J Exp Biol , vol.40 , pp. 1183-1186
    • Velvizhi, S.1    Dakshayani, K.B.2    Subramanian, P.3
  • 78
    • 84859908335 scopus 로고    scopus 로고
    • Neuroprotective effect of Semecarpus anacardium against hyperammonemia in rats
    • Vijayakumar N, Subramanian P. (2010). Neuroprotective effect of Semecarpus anacardium against hyperammonemia in rats. J Pharm Res 3:1564-68.
    • (2010) J Pharm Res , vol.3 , pp. 1564-1568
    • Vijayakumar, N.1    Subramanian, P.2
  • 79
    • 0033058382 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man
    • Walker DK, Ackland MJ, James GC, et al. (1999). Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man. Xenobiotica 29:297-310.
    • (1999) Xenobiotica , vol.29 , pp. 297-310
    • Walker, D.K.1    Ackland, M.J.2    James, G.C.3
  • 80
    • 2342652818 scopus 로고    scopus 로고
    • Fluorescein provides a resonance gate for FRET from conjugated polymers to DNA intercalated dyes
    • Wang S, Gaylord BS, Bazan GC. (2004). Fluorescein provides a resonance gate for FRET from conjugated polymers to DNA intercalated dyes. J Am Chem Soc 126:5446-51.
    • (2004) J Am Chem Soc , vol.126 , pp. 5446-5451
    • Wang, S.1    Gaylord, B.S.2    Bazan, G.C.3
  • 81
    • 15944411036 scopus 로고    scopus 로고
    • Regulation of intracellular Ca2 release in corpus cavernosum smooth muscle: Synergism between nitric oxide and cGMP
    • Williams BA, Liu C, Deyoung L, et al. (2005). Regulation of intracellular Ca2 release in corpus cavernosum smooth muscle: synergism between nitric oxide and cGMP. Am J Physiol Cell Physiol 288:C650-8.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Williams, B.A.1    Liu, C.2    Deyoung, L.3
  • 82
    • 0034123171 scopus 로고    scopus 로고
    • Interactions of oxidants with vascular signaling systems
    • Wolin M. (2000). Interactions of oxidants with vascular signaling systems. Arterioscler Thromb Vasc Biol 20:1430-42.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1430-1442
    • Wolin, M.1
  • 83
    • 0442323504 scopus 로고    scopus 로고
    • Calcineurin-mediated BAD Ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons
    • Yang L, Omori K, Suzukawa J, Inagaki C. (2004). Calcineurin-mediated BAD Ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. Neurosci Lett 357:73-7.
    • (2004) Neurosci Lett , vol.357 , pp. 73-77
    • Yang, L.1    Omori, K.2    Suzukawa, J.3    Inagaki, C.4
  • 84
    • 84861484534 scopus 로고    scopus 로고
    • Yldz H, Durmus AS, Sims-ek H, Yaman M
    • Yldz H, Durmus AS, Sims-ek H, Yaman M. (2012). Dose-dependent protective effect of sildenafil citrate on testicular injury after torsion/ detorsion in rats. Andrologia 44:300-6.
    • (2012) Andrologia , vol.44 , pp. 300-306
  • 86
    • 33646365892 scopus 로고    scopus 로고
    • Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia
    • Zhang RL, Zhang Z, Zhang L, et al. (2006). Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia. J Neurosci Res 83:1213-19.
    • (2006) J Neurosci Res , vol.83 , pp. 1213-1219
    • Zhang, R.L.1    Zhang, Z.2    Zhang, L.3
  • 87
    • 35648945748 scopus 로고    scopus 로고
    • Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices
    • Zielin'ska M, Fresko I, Konopacka A, et al. (2007). Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices. Neurotoxicology 28:1260-3.
    • (2007) Neurotoxicology , vol.28 , pp. 1260-1263
    • Zielin'Ska, M.1    Fresko, I.2    Konopacka, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.