Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man

Xenobiotica

Volumn 29, Issue 3, 1999, Pages 297-310

  Walker, D K ^a   Ackland, M J ^a   James, G C ^a   Muirhead, G J ^a   Rance, D J ^a   Wastall, P ^a   Wright, P A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; PIPERAZINE; SILDENAFIL;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG FECES LEVEL; DRUG HALF LIFE; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG OXIDATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; FEMALE; GASTROINTESTINAL ABSORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; LIVER METABOLISM; LIVER MICROSOME; MALE; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PLASMA PROTEIN BINDING; RABBIT; SPECIES DIFFERENCE;

CANIS FAMILIARIS; ORYCTOLAGUS CUNICULUS; RODENTIA;

EID: 0033058382     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982599238687     Document Type: Article

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