Sildenafil decreased cardiac cell apoptosis in diabetic mice: Reduction of oxidative stress as a possible mechanism

Canadian Journal of Physiology and Pharmacology

Volumn 87, Issue 7, 2009, Pages 556-564

  Ebrahimi, Farzad ^a,b   Shafaroodi, Hamed ^c   Asadi, Shahrzad ^a   Nezami, Behtash Ghazi ^a   Ghasemi, Mehdi ^a   Rahimpour, Sina ^a   Hashemi, Mehrdad ^c   Doostar, Yousef ^d   Dehpour, Ahmad Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Antioxidant; Apoptosis; Diabetes; Heart; Mice; Reactive oxygen species; Sildenafil

Indexed keywords

CASPASE 3; CATALASE; GLUCOSE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; SILDENAFIL; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HEART MUSCLE CELL; HEART PROTECTION; HEART WEIGHT; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; WEIGHT GAIN;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DIABETES MELLITUS, EXPERIMENTAL; MALE; MICE; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PIPERAZINES; PURINES; SULFONES;

EID: 67650924294     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y09-036     Document Type: Article

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