-
1
-
-
0025005862
-
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
-
Fu, J.Y.; Masferrer, J.L.; Seibert, K.; Raz, A.; Needleman, P. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J. Biol. Chem. 1990, 265, 16737-16740.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 16737-16740
-
-
Fu, J.Y.1
Masferrer, J.L.2
Seibert, K.3
Raz, A.4
Needleman, P.5
-
2
-
-
27444432244
-
COX-2 chronology
-
Hawkey, C.J. COX-2 Chronology. Gut 2005, 54, 1509-1514.
-
(2005)
Gut
, vol.54
, pp. 1509-1514
-
-
Hawkey, C.J.1
-
3
-
-
33749828011
-
Imaging of cyclooxygenase-2 (COX-2) expression: Potential use in diagnosis and drug evaluation
-
de Vries, E.F. Imaging of cyclooxygenase-2 (COX-2) expression: Potential use in diagnosis and drug evaluation. Curr. Pharm. Des. 2006, 12, 3847-3856.
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 3847-3856
-
-
De Vries, E.F.1
-
4
-
-
0033791318
-
CYCLOOXYGENASES: Structural, Cellular, and molecular biology
-
Smith, W.L.; DeWitt, D.L.; Garavito, R.M. CYCLOOXYGENASES: Structural, Cellular, and molecular biology. Annu. Rev. Biochem. 2000, 69, 145.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 145
-
-
Smith, W.L.1
Dewitt, D.L.2
Garavito, R.M.3
-
5
-
-
0037207124
-
The cyclooxygenase reaction mechanism
-
van der Donk, W.A.; Tsai, A.; Kulmacz, R.J. The cyclooxygenase reaction mechanism. Biochemistry 2002, 41, 15451-15458.
-
(2002)
Biochemistry
, vol.41
, pp. 15451-15458
-
-
Van Der Donk, W.A.1
Tsai, A.2
Kulmacz, R.J.3
-
6
-
-
0034041077
-
Basic biology and clinical application of specific cyclooxygenase-2 inhibitors
-
Crofford, L.J.; Lipsky, P.E.; Brooks, P.; Abramson, S.B.; Simon, L.S.; van de Putte, L.B. Basic biology and clinical application of specific cyclooxygenase-2 inhibitors. Arthritis Rheum. 2000, 43, 4-13.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 4-13
-
-
Crofford, L.J.1
Lipsky, P.E.2
Brooks, P.3
Abramson, S.B.4
Simon, L.S.5
Van De Putte, L.B.6
-
7
-
-
66349127141
-
Cyclooxygenases: Structural and functional insights
-
Rouzer, C.A.; Marnett, L.J. Cyclooxygenases: Structural and functional insights. J. Lipid Res. 2009, 50, S29-34.
-
(2009)
J. Lipid Res.
, vol.50
-
-
Rouzer, C.A.1
Marnett, L.J.2
-
8
-
-
27144462431
-
COX-2 inhibitors act as radiosensitizer in tumor treatment
-
Sminia, P.; Kuipers, G.; Geldof, A.; Lafleur, V.; Slotman, B. COX-2 inhibitors act as radiosensitizer in tumor treatment. Biomed. Pharmacother. 2005, 59, S272-S275.
-
(2005)
Biomed. Pharmacother.
, vol.59
-
-
Sminia, P.1
Kuipers, G.2
Geldof, A.3
Lafleur, V.4
Slotman, B.5
-
9
-
-
84862546573
-
Inflammation and cancer: Chemical approaches to mechanisms, imaging, and treatment
-
Marnett, L.J. Inflammation and Cancer: Chemical Approaches to Mechanisms, Imaging, and Treatment. J. Org. Chem. 2012, 77, 5224-5238.
-
(2012)
J. Org. Chem.
, vol.77
, pp. 5224-5238
-
-
Marnett, L.J.1
-
10
-
-
84879664815
-
Expression and translation of the COX-1b gene in human cells - No evidence for generation of COX-1b protein
-
Reinauer, C.; Censarek, P.; Kaber, G.; Weber, A.A.; Steger, G.; Klamp, T.; Schror, K. Expression and translation of the COX-1b gene in human cells - No evidence for generation of COX-1b protein. Biol. Chem. 2013, 394, 753-760.
-
(2013)
Biol. Chem.
, vol.394
, pp. 753-760
-
-
Reinauer, C.1
Censarek, P.2
Kaber, G.3
Weber, A.A.4
Steger, G.5
Klamp, T.6
Schror, K.7
-
11
-
-
77955939152
-
The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies
-
doi:10.1155/2010/215158
-
Sobolewski, C.; Cerella, C.; Dicato, M.; Ghibelli, L.; Diederich, M. The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies. Int. J. Cell. Biol. 2010, 2010, doi:10.1155/2010/215158.
-
(2010)
Int. J. Cell. Biol.
, vol.2010
-
-
Sobolewski, C.1
Cerella, C.2
Dicato, M.3
Ghibelli, L.4
Diederich, M.5
-
12
-
-
34147119080
-
Structural and functional basis of Cyclooxygenase inhibition
-
Blobaum, A.L.; Marnett, L.J. Structural and functional basis of Cyclooxygenase inhibition. J. Med. Chem. 2007, 50, 1425-1441.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 1425-1441
-
-
Blobaum, A.L.1
Marnett, L.J.2
-
13
-
-
65249118795
-
The COXIB experience: A look in the rearview mirror
-
Marnett, L.J. The COXIB experience: A look in the rearview mirror. Annu. Rev. Pharmacol. Toxicol. 2009, 49, 265-290.
-
(2009)
Annu. Rev. Pharmacol. Toxicol.
, vol.49
, pp. 265-290
-
-
Marnett, L.J.1
-
14
-
-
69949158726
-
Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and beyond
-
Rao, R.; Knaus, E.E. Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond. J. Pharm. Pharm. Sci. 2008, 11, 81s-110s.
-
(2008)
J. Pharm. Pharm. Sci.
, vol.11
-
-
Rao, R.1
Knaus, E.E.2
-
15
-
-
70350306281
-
Reaching and influencing consumers in the prescription medicine market
-
Peters, J.; Nel, D.; Adam, S. Reaching and influencing consumers in the prescription medicine market. Market Intell. Plann. 2009, 27, 909-925.
-
(2009)
Market Intell. Plann.
, vol.27
, pp. 909-925
-
-
Peters, J.1
Nel, D.2
Adam, S.3
-
16
-
-
80052044604
-
Cyclooxygenase-2 inhibitors: A literature and patent review (2009- 2010)
-
Jawabrah Al-Hourani, B.; Sharma, S.K.; Suresh, M.; Wuest, F. Cyclooxygenase-2 inhibitors: A literature and patent review (2009- 2010). Expert Opin. Ther. Pat. 2011, 21, 1339-1432.
-
(2011)
Expert Opin. Ther. Pat.
, vol.21
, pp. 1339-1432
-
-
Jawabrah Al-Hourani, B.1
Sharma, S.K.2
Suresh, M.3
Wuest, F.4
-
17
-
-
11144224065
-
Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer
-
Soumaoro, L.T.; Uetake, H.; Higuchi, T.; Takagi, Y.; Enomoto, M.; Sugihara, K. Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer. Clin. Cancer Res. 2004, 10, 8465-8471.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 8465-8471
-
-
Soumaoro, L.T.1
Uetake, H.2
Higuchi, T.3
Takagi, Y.4
Enomoto, M.5
Sugihara, K.6
-
18
-
-
33745769736
-
Clinical significance of cyclooxygenase-2 (COX-2) in multiple myeloma
-
Trojan, A.; Tinguely, M.; Vallet, S.; Seifert, B.; Jenni, B.; Zippelius, A.; Witzens-Harig, M.; Mechtersheimer, G.; Ho, A.; Goldschmidt, H.; et al. Clinical significance of cyclooxygenase-2 (COX-2) in multiple myeloma. Swiss Med. Wkly. 2006, 136, 400-403.
-
(2006)
Swiss Med. Wkly.
, vol.136
, pp. 400-403
-
-
Trojan, A.1
Tinguely, M.2
Vallet, S.3
Seifert, B.4
Jenni, B.5
Zippelius, A.6
Witzens-Harig, M.7
Mechtersheimer, G.8
Ho, A.9
Goldschmidt, H.10
-
19
-
-
0034901568
-
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage i non-small cell lung cancer
-
Khuri, F.R.; Wu, H.; Lee, J.J.; Kemp, B.L.; Lotan, R.; Lippman, S.M.; Feng, L.; Hong, W.K.; Xu, X.C. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin. Cancer Res. 2001, 7, 861-867.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 861-867
-
-
Khuri, F.R.1
Wu, H.2
Lee, J.J.3
Kemp, B.L.4
Lotan, R.5
Lippman, S.M.6
Feng, L.7
Hong, W.K.8
Xu, X.C.9
-
20
-
-
0036269556
-
Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer
-
Costa, C.; Soares, R.; Reis-Filho, J.S.; Leitao, D.; Amendoeira, I.; Schmitt, F.C. Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer. J. Clin. Pathol. 2002, 55, 429-434.
-
(2002)
J. Clin. Pathol.
, vol.55
, pp. 429-434
-
-
Costa, C.1
Soares, R.2
Reis-Filho, J.S.3
Leitao, D.4
Amendoeira, I.5
Schmitt, F.C.6
-
21
-
-
35448968987
-
Correlations between Cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer
-
Nakamoto, R.H.; Uetake, H.; Iida, S.; Kolev, Y.V.; Soumaoro, L.T.; Takagi, Y.; Yasuno, M.; Sugihara, K. Correlations between Cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer. Jpn. J. Clin. Oncol. 2007, 37, 679-685.
-
(2007)
Jpn. J. Clin. Oncol.
, vol.37
, pp. 679-685
-
-
Nakamoto, R.H.1
Uetake, H.2
Iida, S.3
Kolev, Y.V.4
Soumaoro, L.T.5
Takagi, Y.6
Yasuno, M.7
Sugihara, K.8
-
22
-
-
77953319891
-
COX-2 as a target for cancer chemotherapy
-
Ghosh, N.; Chaki, R.; Mandal, V.; Mandal, S.C. COX-2 as a target for cancer chemotherapy. Pharmacol. Rep. 2010, 62, 233-244.
-
(2010)
Pharmacol. Rep.
, vol.62
, pp. 233-244
-
-
Ghosh, N.1
Chaki, R.2
Mandal, V.3
Mandal, S.C.4
-
24
-
-
77954950394
-
NSAIDs: Old drugs reveal new anticancer targets
-
Piazza, G.A.; Keeton, A.B.; Tinsley, H.N.; Whitt, J.D.; Gary, B.D.; Mathew, B.; Singh, R.; Grizzle, W.E.; Reynolds, R.C. NSAIDs: Old drugs reveal new anticancer targets. Pharmaceuticals 2010, 3, 1652-1667.
-
(2010)
Pharmaceuticals
, vol.3
, pp. 1652-1667
-
-
Piazza, G.A.1
Keeton, A.B.2
Tinsley, H.N.3
Whitt, J.D.4
Gary, B.D.5
Mathew, B.6
Singh, R.7
Grizzle, W.E.8
Reynolds, R.C.9
-
25
-
-
33746329955
-
Cyclooxygenase-2 (COX-2) expression is an independent predictor of prostate cancer recurrence
-
Cohen, B.L.; Gomez, P.; Omori, Y.; Duncan, R.C.; Civantos, F.; Soloway, M.S.; Lokeshwar, V.B.; Lokeshwar, B.L. Cyclooxygenase-2 (COX-2) expression is an independent predictor of prostate cancer recurrence. Int. J. Cancer 2006, 119, 1082-1087.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 1082-1087
-
-
Cohen, B.L.1
Gomez, P.2
Omori, Y.3
Duncan, R.C.4
Civantos, F.5
Soloway, M.S.6
Lokeshwar, V.B.7
Lokeshwar, B.L.8
-
26
-
-
34548316134
-
Expression of cyclooxygenase-2 and transforming growth factor-beta1 in HCV-induced chronic liver disease and hepatocellular carcinoma
-
El-Bassiouny, A.E.; Zoheiry, M.M.; Nosseir, M.M.; El-Ahwany, E.G.; Ibrahim, R.A.; El- Bassiouni, N.E. Expression of cyclooxygenase-2 and transforming growth factor-beta1 in HCV-induced chronic liver disease and hepatocellular carcinoma. MedGenMed 2007, 9, 45.
-
(2007)
MedGenMed
, vol.9
, pp. 45
-
-
El-Bassiouny, A.E.1
Zoheiry, M.M.2
Nosseir, M.M.3
El-Ahwany, E.G.4
Ibrahim, R.A.5
El- Bassiouni, N.E.6
-
28
-
-
33746504687
-
18F-labeled cyclooxygenase-2 (COX-2) inhibitor as a potential PET imaging agent
-
18F-labeled cyclooxygenase-2 (COX-2) inhibitor as a potential PET imaging agent. J. Labelled Compd. Radiopharmaceut. 2006, 49, 583-593.
-
(2006)
J. Labelled Compd. Radiopharmaceut.
, vol.49
, pp. 583-593
-
-
Tian, H.1
Lee, Z.2
-
31
-
-
84861197495
-
18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo
-
18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo. Bioorg. Med. Chem. 2012, 20, 3410-3421.
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 3410-3421
-
-
Kniess, T.1
Laube, M.2
Bergmann, R.3
Sehn, F.4
Graf, F.5
Steinbach, J.6
Wuest, F.7
Pietzsch, J.8
-
33
-
-
25144508684
-
18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography
-
18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography. Bioorg. Med. Chem. Lett. 2005, 15, 4699-4702.
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 4699-4702
-
-
Toyokuni, T.1
Kumar, J.S.2
Walsh, J.C.3
Shapiro, A.4
Talley, J.J.5
Phelps, M.E.6
Herschman, H.R.7
Barrio, J.R.8
Satyamurthy, N.9
-
34
-
-
84879666006
-
18F]labeled COX-2 inhibitors
-
25-29 March
-
18F]labeled COX-2 inhibitors. In Proceedings of The 233rd ACS National Meeting, Chicago, IL, USA, 25-29 March, 2007; p. FLUO-014.
-
(2007)
Proceedings of the 233rd ACS National Meeting, Chicago, IL, USA
-
-
Kumar, J.S.D.1
Mann, J.J.2
-
35
-
-
79961100186
-
11C-Labeled analogs of indomethacin esters and amides for brain cyclooxygenase-2 imaging: Radiosynthesis, in vitro evaluation and in vivo characteristics in mice
-
11C-Labeled analogs of indomethacin esters and amides for brain cyclooxygenase-2 imaging: Radiosynthesis, in vitro evaluation and in vivo characteristics in mice. Chem. Pharm. Bull. 2011, 59, 938-946.
-
(2011)
Chem. Pharm. Bull.
, vol.59
, pp. 938-946
-
-
Yamamoto, Y.1
Toyohara, J.2
Ishiwata, K.3
Sano, K.4
Yamamoto, F.5
Mukai, T.6
Maeda, M.7
-
36
-
-
79960336672
-
11C- ketoprofen methyl ester
-
11C-ketoprofen methyl ester. J. Nucl. Med. 2011, 52, 1094-1101.
-
(2011)
J. Nucl. Med.
, vol.52
, pp. 1094-1101
-
-
Shukuri, M.1
Takashima-Hirano, M.2
Tokuda, K.3
Takashima, T.4
Matsumura, K.5
Inoue, O.6
Doi, H.7
Suzuki, M.8
Watanabe, Y.9
Onoe, H.10
-
37
-
-
84879619586
-
2,3-Diaryl substituted indoles as probes for monitoring cyclooxygenase-2 (COX-2) with PET-radiolabeling, in vitro and in vivo studies
-
Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; Pietzsch, J. 2,3-Diaryl substituted indoles as probes for monitoring cyclooxygenase-2 (COX-2) with PET-radiolabeling, in vitro and in vivo studies. Nuklearmedizin 2012, 51, A11-A12.
-
(2012)
Nuklearmedizin
, vol.51
-
-
Kniess, T.1
Laube, M.2
Bergmann, R.3
Graf, F.4
Steinbach, J.5
Pietzsch, J.6
-
38
-
-
84879639850
-
Synthesis and evaluation of a radioiodinated coxib as a spect tracer for cyclooxygenase-2 expression
-
Kuge, Y.; Shimonaka, S.; Katada, Y.; Temma, T.; Kimura, H.; Kiyono, Y.; Yokota, C.; Minematsu, K.K.; Seki, K.; Tamaki, N.; et al. Synthesis and evaluation of a radioiodinated coxib as a spect tracer for cyclooxygenase-2 expression. J. Labelled Compd. Radiopharm. 2005, 48, S297.
-
(2005)
J. Labelled Compd. Radiopharm.
, vol.48
-
-
Kuge, Y.1
Shimonaka, S.2
Katada, Y.3
Temma, T.4
Kimura, H.5
Kiyono, Y.6
Yokota, C.7
Minematsu, K.K.8
Seki, K.9
Tamaki, N.10
-
39
-
-
31844440302
-
Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression
-
Kuge, Y.; Katada, Y.; Shimonaka, S.; Temma, T.; Kimura, H.; Kiyono, Y.; Yokota, C.; Minematsu, K.; Seki, K.; Tamaki, N.; et al. Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression. Nucl. Med. Biol. 2006, 33, 21-27.
-
(2006)
Nucl. Med. Biol.
, vol.33
, pp. 21-27
-
-
Kuge, Y.1
Katada, Y.2
Shimonaka, S.3
Temma, T.4
Kimura, H.5
Kiyono, Y.6
Yokota, C.7
Minematsu, K.8
Seki, K.9
Tamaki, N.10
-
40
-
-
79551683046
-
11C]diclofenac sodium: Synthesis and PET assessment of transdermal penetration
-
11C]diclofenac sodium: synthesis and PET assessment of transdermal penetration. Nucl. Med. Biol. 2011, 38, 181-189.
-
(2011)
Nucl. Med. Biol.
, vol.38
, pp. 181-189
-
-
Petroni, D.1
Menichetti, L.2
Sorace, O.3
Poli, M.4
Vanasia, M.5
Salvadori, P.A.6
-
41
-
-
14244263019
-
18F]fluoroiodobenzene as radiotracers for positron emission tomography (PET)
-
18F]fluoroiodobenzene as radiotracers for positron emission tomography (PET). Org. Biomol. Chem. 2005, 3, 503-507.
-
(2005)
Org. Biomol. Chem.
, vol.3
, pp. 503-507
-
-
Wuest, F.1
Höhne, A.2
Metz, P.3
-
42
-
-
23944452354
-
11C] methylsulfones: Potential PET probes for imaging cyclooxygenase-2 expression
-
11C]methylsulfones: potential PET probes for imaging cyclooxygenase-2 expression. Bioorg. Med. Chem. Lett. 2005, 15, 4268-4271.
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 4268-4271
-
-
Majo, V.J.1
Prabhakaran, J.2
Simpson, N.R.3
Van Heertum, R.L.4
Mann, J.J.5
Kumar, J.S.6
-
43
-
-
33749427395
-
11C-labeled diaryl-substituted imidazole and indole derivatives for mapping cyclooxygenase-2
-
11C-labeled diaryl-substituted imidazole and indole derivatives for mapping cyclooxygenase-2. Biol. Pharm. Bull. 2006, 29, 2087-2094.
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 2087-2094
-
-
Tanaka, M.1
Fujisaki, Y.2
Kawamura, K.3
Ishiwata, K.4
Qinggeletu5
Yamamoto, F.6
Mukai, T.7
Maeda, M.8
-
44
-
-
33847783301
-
18F]-4-[5-(4- methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression
-
18F]-4-[5-(4- methylphenyl)-3-(trifluoromethyl)-1H- pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression. Bioorg. Med. Chem. 2007, 15, 1802-1807.
-
(2007)
Bioorg. Med. Chem.
, vol.15
, pp. 1802-1807
-
-
Prabhakaran, J.1
Underwood, M.D.2
Parsey, R.V.3
Arango, V.4
Majo, V.J.5
Simpson, N.R.6
Van Heertum, R.7
Mann, J.J.8
Kumar, J.S.9
-
45
-
-
77950846318
-
11C-labeling of 2-arylpropionic acids and their esters: Construction of a PET tracer library for a study of biological events involved in COXs expression
-
11C-labeling of 2-arylpropionic acids and their esters: Construction of a PET tracer library for a study of biological events involved in COXs expression. Chem. Eur. J. 2010, 16, 4250-4258.
-
(2010)
Chem. Eur. J.
, vol.16
, pp. 4250-4258
-
-
Takashima-Hirano, M.1
Shukuri, M.2
Takashima, T.3
Goto, M.4
Wada, Y.5
Watanabe, Y.6
Onoe, H.7
Doi, H.8
Suzuki, M.9
-
46
-
-
80052920865
-
Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancer
-
Gao, M.; Wang, M.; Miller, K.D.; Zheng, Q. Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancer. Eur. J. Med. Chem. 2011, 46, 4760-4767.
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 4760-4767
-
-
Gao, M.1
Wang, M.2
Miller, K.D.3
Zheng, Q.4
-
47
-
-
84879618405
-
11C]-TMI: A Potential PET Tracer for Imaging COX-2 Expression
-
22-26 August
-
11C]-TMI: A Potential PET Tracer for Imaging COX-2 Expression. In Proceedings of the 228th ACS National Meeting, Philadelphia, PA, USA, 22-26 August, 2004; p. MEDI-244.
-
(2004)
Proceedings of the 228th ACS National Meeting, Philadelphia, PA, USA
-
-
Kumar, J.S.D.1
Underwood, M.D.2
Prabhakaran, J.3
Parsey, R.V.4
Arango, V.5
Majo, V.J.6
Simpson, N.R.7
Cooper, A.R.8
Arcement, J.9
Van Heertum, R.L.10
-
48
-
-
80053905361
-
Fluorinated cyclooxygenase-2 inhibitors as agents in PET imaging of inflammation and cancer
-
Uddin, M.J.; Crews, B.C.; Ghebreselasie, K.; Huda, I.; Kingsley, P.J.; Ansari, M.S.; Tantawy, M.N.; Reese, J.J.; Marnett, L.J. Fluorinated cyclooxygenase-2 inhibitors as agents in PET imaging of inflammation and cancer. Cancer Prev. Res. 2011, 4, 1536-1545.
-
(2011)
Cancer Prev. Res.
, vol.4
, pp. 1536-1545
-
-
Uddin, M.J.1
Crews, B.C.2
Ghebreselasie, K.3
Huda, I.4
Kingsley, P.J.5
Ansari, M.S.6
Tantawy, M.N.7
Reese, J.J.8
Marnett, L.J.9
-
49
-
-
68949159012
-
Synthesis and ealuation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents
-
Uddin, M.J.; Crews, B.C.; Blobaum, A.L.; Kingsley, P.J.; Ghebreselasie, K.; Saleh, S.S.; Clanton, J.A.; Baldwin, R.M.; Marnett, L.J. Synthesis and ealuation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents. J. Labelled Compd. Radiopharm. 2009, 52, 387-393.
-
(2009)
J. Labelled Compd. Radiopharm.
, vol.52
, pp. 387-393
-
-
Uddin, M.J.1
Crews, B.C.2
Blobaum, A.L.3
Kingsley, P.J.4
Ghebreselasie, K.5
Saleh, S.S.6
Clanton, J.A.7
Baldwin, R.M.8
Marnett, L.J.9
-
51
-
-
31544468363
-
11C-labeled 1,5-diarylpyrazole derivatives for mapping cyclooxygenases
-
11C-labeled 1,5-diarylpyrazole derivatives for mapping cyclooxygenases. Ann. Nucl. Med. 2005, 19, 617-625.
-
(2005)
Ann. Nucl. Med.
, vol.19
, pp. 617-625
-
-
Fujisaki, Y.1
Kawamura, K.2
Wang, W.3
Ishiwata, K.4
Yamamoto, F.5
Kuwano, T.6
Ono, M.7
Maeda, M.8
-
52
-
-
17444431148
-
Synthesis of an iodine-123-labeled celecoxib analogue: A potential spect agent
-
Kabalka, G.W.; Mereddy, A.R.; Schuller, H.M. Synthesis of an iodine-123-labeled celecoxib analogue: a potential spect agent. J. Labelled Compd. Radiopharm. 2005, 48, 295-300.
-
(2005)
J. Labelled Compd. Radiopharm.
, vol.48
, pp. 295-300
-
-
Kabalka, G.W.1
Mereddy, A.R.2
Schuller, H.M.3
-
53
-
-
33746311569
-
Detection of Overexpressed COX-2 in precancerous lesions of hamster pancreas and lungs by molecular imaging: Implications for early diagnosis and prevention
-
Schuller, H.M.; Kabalka, G.; Smith, G.; Mereddy, A.; Akula, M.; Cekanova, M. Detection of Overexpressed COX-2 in precancerous lesions of hamster pancreas and lungs by molecular imaging: Implications for early diagnosis and prevention. ChemMedChem 2006, 1, 603-610.
-
(2006)
ChemMedChem
, vol.1
, pp. 603-610
-
-
Schuller, H.M.1
Kabalka, G.2
Smith, G.3
Mereddy, A.4
Akula, M.5
Cekanova, M.6
-
54
-
-
12144291289
-
99mTc-labeled celebrex
-
99mTc-labeled celebrex. Anticancer Drugs 2004, 15, 255-263.
-
(2004)
Anticancer Drugs
, vol.15
, pp. 255-263
-
-
Yang, D.J.1
Bryant, J.2
Chang, J.Y.3
Mendez, R.4
Oh, C.S.5
Yu, D.F.6
Ito, M.7
Azhdarinia, A.8
Kohanim, S.9
Edmund Kim, E.10
Lin, E.11
Podoloff, D.A.12
-
55
-
-
84856097606
-
Maximal standardized uptake value on FDG-PET is correlated with cyclooxygenase-2 expression in patients with lung adenocarcinoma
-
Shimizu, K.; Hirami, Y.; Saisho, S.; Yukawa, T.; Maeda, A.; Yasuda, K.; Nakata, M. Maximal standardized uptake value on FDG-PET is correlated with cyclooxygenase-2 expression in patients with lung adenocarcinoma. Ann. Thorac. Surg. 2012, 93, 398-403.
-
(2012)
Ann. Thorac. Surg.
, vol.93
, pp. 398-403
-
-
Shimizu, K.1
Hirami, Y.2
Saisho, S.3
Yukawa, T.4
Maeda, A.5
Yasuda, K.6
Nakata, M.7
-
57
-
-
0242383300
-
In vivo approaches to quantifying and imaging brain arachidonic and docosahexaenoic acid metabolism
-
Rapoport, S.I. In vivo approaches to quantifying and imaging brain arachidonic and docosahexaenoic acid metabolism. J. Pediatr. 2003, 143, 26-34.
-
(2003)
J. Pediatr.
, vol.143
, pp. 26-34
-
-
Rapoport, S.I.1
-
58
-
-
33749864391
-
11C]indomethacin methyl ester for in vivo brain studies of cyclooxygenase-2
-
11C]indomethacin methyl ester for in vivo brain studies of cyclooxygenase-2. J. Nucl. Med. 1996, 37, 192P.
-
(1996)
J. Nucl. Med.
, vol.37
-
-
Del Rosario1
-
60
-
-
84879649254
-
11C]-Celecoxib: A Potential PET tracer for imaging COX-2 Expression
-
7-11 September
-
11C]-Celecoxib: A Potential PET tracer for imaging COX-2 Expression. In Proceedings of the 226th ACS National Meeting, New York, NY, USA, 7-11 September, 2003; p. MEDI-375.
-
(2003)
Proceedings of the 226th ACS National Meeting, New York, NY, USA
-
-
Kumar, J.S.D.1
Prabhakaran, J.2
Underwood, M.D.3
Parsey, R.V.4
Arango, V.5
Majo, V.J.6
Simpson, N.R.7
Arcement, J.8
Cooper, A.R.9
Van Heertum, R.R.10
-
61
-
-
27844543335
-
11C]celecoxib: A potential PET probe for imaging COX-2 expression
-
11C]celecoxib: A potential PET probe for imaging COX-2 expression. J. Labelled Compd. Radiopharm. 2005, 48, 887-895.
-
(2005)
J. Labelled Compd. Radiopharm.
, vol.48
, pp. 887-895
-
-
Prabhakaran, J.1
Majo, V.J.2
Simpson, N.R.3
Van Heertum, R.L.4
Mann, J.J.5
Kumar, J.S.D.6
-
62
-
-
13444266910
-
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)- 3(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (Sc-58635, celecoxib)
-
Penning, T.D.; Talley, J.J.; Bertenshaw, S.R.; Carter, J.S.; Collins, P.W.; Docter, S.; Graneto, M.J.; Lee, L.F.; Malecha, J.W.; Miyashiro, J.M.; et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)- 3(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (Sc-58635, celecoxib). J. Med. Chem. 1997, 40, 1347-1365.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 1347-1365
-
-
Penning, T.D.1
Talley, J.J.2
Bertenshaw, S.R.3
Carter, J.S.4
Collins, P.W.5
Docter, S.6
Graneto, M.J.7
Lee, L.F.8
Malecha, J.W.9
Miyashiro, J.M.10
-
63
-
-
84879610863
-
Efficient O-[C- 11]Methylation with [C-11]methyl triflate: Synthesis of C-11-labeled diaryl substituted pyrazole and imidazole cyclooxygenase inhibitors
-
Kawamura, K.; Fujisaki, Y.; Ishiwata, K.; Yamamoto, F.; Maeda, M. Efficient O-[C- 11]Methylation with [C-11]methyl triflate: Synthesis of C-11-labeled diaryl substituted pyrazole and imidazole cyclooxygenase inhibitors. J. Labelled Compd. Radiopharm. 2005, 48, S206.
-
(2005)
J. Labelled Compd. Radiopharm.
, vol.48
-
-
Kawamura, K.1
Fujisaki, Y.2
Ishiwata, K.3
Yamamoto, F.4
Maeda, M.5
-
64
-
-
0042343839
-
Synthesis and structure-Activity relationship of a new series of COX-2 selective inhibitors: 1,5-Diarylimidazoles
-
Almansa, C.; Alfón, J.; de Arriba, A.F.; Cavalcanti, F.L.; Escamilla, I.; Gómez, L.A.; Miralles, A.; Soliva, R.; Bartrolí, J.; Carceller, E.; et al. Synthesis and structure-Activity relationship of a new series of COX-2 selective inhibitors: 1,5-Diarylimidazoles. J. Med. Chem. 2003, 46, 3463-3475.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 3463-3475
-
-
Almansa, C.1
Alfón, J.2
De Arriba, A.F.3
Cavalcanti, F.L.4
Escamilla, I.5
Gómez, L.A.6
Miralles, A.7
Soliva, R.8
Bartrolí, J.9
Carceller, E.10
-
65
-
-
0242362591
-
Design, Synthesis, and biological evaluation of 6-Substituted-3-(4- methanesulfonylphenyl)-4-phenylpyran-2-ones: A novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors
-
Praveen Rao, P.N.; Amini, M.; Li, H.; Habeeb, A.G.; Knaus, E.E. Design, Synthesis, And biological evaluation of 6-Substituted-3-(4- methanesulfonylphenyl)-4-phenylpyran-2-ones: A novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors. J. Med. Chem. 2003, 46, 4872-4882.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4872-4882
-
-
Praveen Rao, P.N.1
Amini, M.2
Li, H.3
Habeeb, A.G.4
Knaus, E.E.5
-
66
-
-
0037375844
-
Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3- phenyl-indoles: A new series of selective COX-2 inhibitors
-
Hu, W.; Guo, Z.; Chu, F.; Bai, A.; Yi, X.; Cheng, G.; Li, J. Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: A new series of selective COX-2 inhibitors. Bioorg. Med. Chem. 2003, 11, 1153-1160.
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 1153-1160
-
-
Hu, W.1
Guo, Z.2
Chu, F.3
Bai, A.4
Yi, X.5
Cheng, G.6
Li, J.7
-
67
-
-
43049157982
-
Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study
-
de Vries, E.F.J.; Doorduin, J.; Vellinga, N.A.R.; van Waarde, A.; Dierckx, R.A.; Klein, H.C. Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study. Nucl. Med. Biol. 2008, 35, 459-466.
-
(2008)
Nucl. Med. Biol.
, vol.35
, pp. 459-466
-
-
De Vries, E.F.J.1
Doorduin, J.2
Vellinga, N.A.R.3
Van Waarde, A.4
Dierckx, R.A.5
Klein, H.C.6
-
68
-
-
77950806273
-
11C]methylation using an organoboron precursor and pet imaging of COX-2 expression in rat brains
-
11C] methylation using an organoboron precursor and pet imaging of COX-2 expression in rat brains. J. Labelled Compd. Radiopharm. 2009, 52, S435.
-
(2009)
J. Labelled Compd. Radiopharm.
, vol.52
-
-
Takashima-Hirano, M.1
Cui, Y.2
Takashima, T.3
Hayashinaka, E.4
Wada, Y.5
Watanabe, Y.6
Doi, H.7
Suzuki, M.8
-
69
-
-
1242271959
-
Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2
-
Riendeau, D.; Salem, M.; Styhler, A.; Ouellet, M.; Mancini, J.A.; Li, C.S. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg. Med. Chem. Lett. 2004, 14, 1201-1203.
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 1201-1203
-
-
Riendeau, D.1
Salem, M.2
Styhler, A.3
Ouellet, M.4
Mancini, J.A.5
Li, C.S.6
-
70
-
-
0033594911
-
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
-
Warner, T.D.; Giuliano, F.; Vojnovic, I.; Bukasa, A.; Mitchell, J.A.; Vane, J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis. Proc. Natl. Acad. Sci. USA 1999, 96, 7563-7568.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7563-7568
-
-
Warner, T.D.1
Giuliano, F.2
Vojnovic, I.3
Bukasa, A.4
Mitchell, J.A.5
Vane, J.R.6
-
72
-
-
79956191076
-
11C-labeled ibuprofen assisted by DMSO for imaging of in vivo behavior of the individual isomers by positron emission tomography
-
11C-labeled ibuprofen assisted by DMSO for imaging of in vivo behavior of the individual isomers by positron emission tomography. Bioorg. Med. Chem. 2011, 19, 3265-3273.
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 3265-3273
-
-
Kikuchi, T.1
Okada, M.2
Nengaki, N.3
Furutsuka, K.4
Wakizaka, H.5
Okamura, T.6
Zhang, M.7
Kato, K.8
-
73
-
-
84879628935
-
Synthesis and radiopharmacological evaluation of F-18-labeled peptides for targeting COX-2
-
Al-Hourani, B.J.; Sharma Sai, K.; Wang, M.; Suresh, M.; Wuest, F. Synthesis and radiopharmacological evaluation of F-18-labeled peptides for targeting COX-2. J. Labelled Compd. Radiopharm. 2011, 54, S203.
-
(2011)
J. Labelled Compd. Radiopharm.
, vol.54
-
-
Al-Hourani, B.J.1
Sharma Sai, K.2
Wang, M.3
Suresh, M.4
Wuest, F.5
-
74
-
-
84863419870
-
Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2)
-
Sharma, S.K.; Al-Hourani, B.J.; Wuest, M.; Mane, J.Y.; Tuszynski, J.; Baracos, V.; Suresh, M.; Wuest, F. Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2). Bioorg. Med. Chem. 2012, 20, 2221-2226.
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 2221-2226
-
-
Sharma, S.K.1
Al-Hourani, B.J.2
Wuest, M.3
Mane, J.Y.4
Tuszynski, J.5
Baracos, V.6
Suresh, M.7
Wuest, F.8
-
75
-
-
79955483866
-
11C]SC-62807 and in vivo PET evaluation
-
11C]SC-62807 and in vivo PET evaluation. Bioorg. Med. Chem. 2011, 19, 2997-3004.
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 2997-3004
-
-
Takashima-Hirano, M.1
Takashima, T.2
Katayama, Y.3
Wada, Y.4
Sugiyama, Y.5
Watanabe, Y.6
Doi, H.7
Suzuki, M.8
-
76
-
-
0034721194
-
Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors
-
Kalgutkar, A.S.; Marnett, A.B.; Crews, B.C.; Remmel, R.P.; Marnett, L.J. Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors. J. Med. Chem. 2000, 43, 2860-2870.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 2860-2870
-
-
Kalgutkar, A.S.1
Marnett, A.B.2
Crews, B.C.3
Remmel, R.P.4
Marnett, L.J.5
-
77
-
-
84879646728
-
18F-labeling-radiosynthesis of a 2,3-diarylsubstituted COX-2 inhibitor
-
18F-labeling-radiosynthesis of a 2,3-diarylsubstituted COX-2 inhibitor. J. Labelled Compd. Radiopharm. 2011, 54, S73.
-
(2011)
J. Labelled Compd. Radiopharm.
, vol.54
-
-
Laube, M.1
Kniess, T.2
Bergmann, R.3
Steinbach, J.4
Pietzsch, J.5
-
79
-
-
77951738107
-
Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents
-
Uddin, M.J.; Crews, B.C.; Blobaum, A.L.; Kingsley, P.J.; Gorden, D.L.; McIntyre, J.O.; Matrisian, L.M.; Subbaramaiah, K.; Dannenberg, A.J.; Piston, D.W.; et al. Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents. Cancer Res. 2010, 70, 3618-3627.
-
(2010)
Cancer Res.
, vol.70
, pp. 3618-3627
-
-
Uddin, M.J.1
Crews, B.C.2
Blobaum, A.L.3
Kingsley, P.J.4
Gorden, D.L.5
McIntyre, J.O.6
Matrisian, L.M.7
Subbaramaiah, K.8
Dannenberg, A.J.9
Piston, D.W.10
-
80
-
-
70350234582
-
Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression
-
Kuge, Y.; Obokata, N.; Kimura, H.; Katada, Y.; Temma, T.; Sugimoto, Y.; Aita, K.; Seki, K.; Tamaki, N.; Saji, H. Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression. Nucl. Med. Biol. 2009, 36, 869-876.
-
(2009)
Nucl. Med. Biol.
, vol.36
, pp. 869-876
-
-
Kuge, Y.1
Obokata, N.2
Kimura, H.3
Katada, Y.4
Temma, T.5
Sugimoto, Y.6
Aita, K.7
Seki, K.8
Tamaki, N.9
Saji, H.10
-
81
-
-
77955513927
-
Preparation of 125I-celecoxib with high purity as a possible tumor agent
-
El-Azony, K. Preparation of 125I-celecoxib with high purity as a possible tumor agent. J. Radioanal. Nucl. 2010, 285, 315-320.
-
(2010)
J. Radioanal. Nucl.
, vol.285
, pp. 315-320
-
-
El-Azony, K.1
-
82
-
-
84879624134
-
Radioiodinated Indometacin Amides as COX-2-Specific Tracers: Synthesis and Initial in Vitro Study
-
Zlatopolskiy, B.D.; Vogg, A.; Neumaier, B.; Mottaghy, F.M.; Morgenroth, A. Radioiodinated Indometacin Amides as COX-2-Specific Tracers: Synthesis and Initial in Vitro Study. Eur. J. Nucl. Med. Mol. Imaging 2012, 39, S216.
-
(2012)
Eur. J. Nucl. Med. Mol. Imaging
, vol.39
-
-
Zlatopolskiy, B.D.1
Vogg, A.2
Neumaier, B.3
Mottaghy, F.M.4
Morgenroth, A.5
-
83
-
-
53749088838
-
Site specific chemical delivery of NSAIDs to inflamed joints: Synthesis, Biological activity and γ-imaging studies of quaternary ammonium salts of tropinol esters of some NSAIDs or their active metabolites
-
Yadav, M.R.; Pawar, V.P.; Marvaniya, S.M.; Halen, P.K.; Giridhar, R.; Mishra, A.K. Site specific chemical delivery of NSAIDs to inflamed joints: Synthesis, Biological activity and γ-imaging studies of quaternary ammonium salts of tropinol esters of some NSAIDs or their active metabolites. Bioorg. Med. Chem. 2008, 16, 9443-9449.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 9443-9449
-
-
Yadav, M.R.1
Pawar, V.P.2
Marvaniya, S.M.3
Halen, P.K.4
Giridhar, R.5
Mishra, A.K.6
-
84
-
-
84860475786
-
Cartilage targeted chemical delivery of naproxen and ibuprofen for the treatment of arthritis
-
Yadav, M.; Giridhar, R.; Tamboli, R.; Pawar, V.; Gohil, V. Cartilage targeted chemical delivery of naproxen and ibuprofen for the treatment of arthritis. J. Pharm. Bioall. Sci. 2012, 4, 10-11.
-
(2012)
J. Pharm. Bioall. Sci.
, vol.4
, pp. 10-11
-
-
Yadav, M.1
Giridhar, R.2
Tamboli, R.3
Pawar, V.4
Gohil, V.5
-
86
-
-
77955714043
-
Triaryl (Z)-olefins suitable for radiolabeling with carbon-11 or fluorine-18 radionuclides for positron emission tomography imaging of cyclooxygenase-2 expression in pathological disease
-
Abdellatif, K.R.A.; Velázquez, C.A.; Huang, Z.; Chowdhury, M.A.; Knaus, E.E. Triaryl (Z)-olefins suitable for radiolabeling with carbon-11 or fluorine-18 radionuclides for positron emission tomography imaging of cyclooxygenase-2 expression in pathological disease. Bioorg. Med. Chem. Lett. 2010, 20, 5245-5250.
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 5245-5250
-
-
Abdellatif, K.R.A.1
Velázquez, C.A.2
Huang, Z.3
Chowdhury, M.A.4
Knaus, E.E.5
|