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Volumn 20, Issue 7, 2012, Pages 2221-2226
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Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2)
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Author keywords
COX 2 inhibitors; Cyclooxygenase; Molecular probes; Peptides
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Indexed keywords
CELECOXIB;
CYCLOOXYGENASE 2 INHIBITOR;
DIPEPTIDE;
FLUOROBENZOYLATED CYSTYLASPARTIC ACID;
FLUOROBENZOYLATED CYSTYLSERINE;
FLUOROBENZOYLATED PHENYLALANYLCYSTYLSERINE;
FLUOROBENZOYLATED PHENYLALANYLMETHIONYLASPARTIC ACID;
FLUOROBENZOYLATED PHENYLALANYLMETHIONYLGLUTAMIC ACID;
FLUOROBENZOYLATED TRYPTOPHANYLMETHIONYLASPARTIC ACID;
FLUOROBENZOYLATED TRYPTOPHANYLMETHIONYLGLUTAMIC ACID;
FLUOROBENZOYLATED TRYPTOPHANYLSERINE;
FLUOROBENZOYLATED TRYPTOPHANYLTYROSYLASPARTIC ACID;
FLUOROBENZOYLATED TRYPTOPHANYLTYROSYLSERINE;
FLUOROBENZOYLATED TYROSYLASPARTIC ACID;
FLUOROBENZOYLATED TYROSYLSERINE;
TRIPEPTIDE;
UNCLASSIFIED DRUG;
ARTICLE;
CONTROLLED STUDY;
DRUG POTENCY;
DRUG PROTEIN BINDING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TARGETING;
ENZYME ACTIVE SITE;
ENZYME ASSAY;
ENZYME INHIBITION;
IC 50;
IN VITRO STUDY;
MOLECULAR DOCKING;
PEPTIDE ANALYSIS;
PEPTIDE SYNTHESIS;
STRUCTURE ACTIVITY RELATION;
AMINO ACID SEQUENCE;
ANIMALS;
BENZOIC ACID;
BINDING SITES;
CATALYTIC DOMAIN;
CYCLOOXYGENASE 2;
CYCLOOXYGENASE 2 INHIBITORS;
DIPEPTIDES;
FLUORINE;
HYDROGEN BONDING;
MICE;
MOLECULAR DYNAMICS SIMULATION;
OLIGOPEPTIDES;
SOLID-PHASE SYNTHESIS TECHNIQUES;
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EID: 84863419870
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.02.021 Document Type: Article |
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Times cited : (15)
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References (27)
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