[123I]-celecoxib analogues as SPECT tracers of cyclooxygenase-2 in inflammation

ACS Medicinal Chemistry Letters

Volumn 2, Issue 2, 2011, Pages 160-164

  Uddin, Md Jashim ^a   Crews, Brenda C ^a   Ghebreselasie, Kebreab ^a   Tantawy, Mohammed N ^a   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

celecoxib; cyclooxygenase 2 (COX 2); in vivo SPECT imaging; Iodine 123; iododestannylation; two phase reaction

Indexed keywords

5 (4 IODOPHENYL) 1 [4 (METHYLSULFONYL)PHENYL]3 (TRIFLUOROMETHYL) 1H PYRAZOLE I 123; ANTIINFLAMMATORY AGENT; CELECOXIB; CELECOXIB I 123; CYCLOOXYGENASE 2; TOSYLCHLORAMIDE SODIUM; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; IC 50; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RADIOCHEMISTRY; RADIOIODINATION; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STRUCTURE ACTIVITY RELATION;

RATTUS;

EID: 79951525814     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml100232q     Document Type: Article

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