-
1
-
-
77950479742
-
"Divine stramonium": The rise and fall of smoking for asthma
-
M. Jackson "Divine stramonium": the rise and fall of smoking for asthma Med Hist 54 2010 171 194
-
(2010)
Med Hist
, vol.54
, pp. 171-194
-
-
Jackson, M.1
-
2
-
-
84873170983
-
Muscarinic receptors on airway mesenchymal cells: Novel findings for an ancient target
-
H. Meurs, B.G. Dekkers, H. Maarsingh, A.J. Halayko, J. Zaagsma, and R. Gosens Muscarinic receptors on airway mesenchymal cells: novel findings for an ancient target Pulm Pharmacol Ther 26 2013 145 155
-
(2013)
Pulm Pharmacol Ther
, vol.26
, pp. 145-155
-
-
Meurs, H.1
Dekkers, B.G.2
Maarsingh, H.3
Halayko, A.J.4
Zaagsma, J.5
Gosens, R.6
-
3
-
-
33745218112
-
Muscarinic receptor signaling in the pathophysiology of asthma and COPD
-
R. Gosens, J. Zaagsma, H. Meurs, and A.J. Halayko Muscarinic receptor signaling in the pathophysiology of asthma and COPD Respir Res 7 2006 73
-
(2006)
Respir Res
, vol.7
, pp. 73
-
-
Gosens, R.1
Zaagsma, J.2
Meurs, H.3
Halayko, A.J.4
-
4
-
-
71249094666
-
Alternative mechanisms for tiotropium
-
E.D. Bateman, S. Rennard, P.J. Barnes, P.V. Dicpinigaitis, R. Gosens, N.J. Gross, J.A. Nadel, M. Pfeifer, K. Racke, K.F. Rabe, B.K. Rubin, T. Welte, and I. Wessler Alternative mechanisms for tiotropium Pulm Pharmacol Ther 22 2009 533 542
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 533-542
-
-
Bateman, E.D.1
Rennard, S.2
Barnes, P.J.3
Dicpinigaitis, P.V.4
Gosens, R.5
Gross, N.J.6
Nadel, J.A.7
Pfeifer, M.8
Racke, K.9
Rabe, K.F.10
Rubin, B.K.11
Welte, T.12
Wessler, I.13
-
5
-
-
84872826158
-
Regulation of airway inflammation and remodeling by muscarinic receptors: Perspectives on anticholinergic therapy in asthma and COPD
-
L.E. Kistemaker, T.A. Oenema, H. Meurs, and R. Gosens Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD Life Sci 91 2012 1126 1133
-
(2012)
Life Sci
, vol.91
, pp. 1126-1133
-
-
Kistemaker, L.E.1
Oenema, T.A.2
Meurs, H.3
Gosens, R.4
-
6
-
-
49449094458
-
Acetylcholine beyond neurons: The non-neuronal cholinergic system in humans
-
I. Wessler, and C.J. Kirkpatrick Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans Br J Pharmacol 154 2008 1558 1571
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1558-1571
-
-
Wessler, I.1
Kirkpatrick, C.J.2
-
8
-
-
33748475192
-
Reflex regulation of airway smooth muscle tone
-
B.J. Canning Reflex regulation of airway smooth muscle tone J Appl Physiol 101 2006 971 985
-
(2006)
J Appl Physiol
, vol.101
, pp. 971-985
-
-
Canning, B.J.1
-
9
-
-
0035722962
-
Pharmacology of airway afferent nerve activity
-
B.J. Undem, and M.J. Carr Pharmacology of airway afferent nerve activity Respir Res 2 2001 234 244
-
(2001)
Respir Res
, vol.2
, pp. 234-244
-
-
Undem, B.J.1
Carr, M.J.2
-
10
-
-
27644530096
-
Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease
-
K.E. Belmonte Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease Proc Am Thorac Soc 2 2005 297 304
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 297-304
-
-
Belmonte, K.E.1
-
11
-
-
48749124897
-
The epithelial cholinergic system of the airways
-
W. Kummer, K.S. Lips, and U. Pfeil The epithelial cholinergic system of the airways Histochem Cell Biol 130 2008 219 234
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 219-234
-
-
Kummer, W.1
Lips, K.S.2
Pfeil, U.3
-
12
-
-
0033534194
-
Tiotropium (Spiriva): Mechanistical considerations and clinical profile in obstructive lung disease
-
B. Disse, G.A. Speck, K.L. Rominger, T.J. Witek Jr., and R. Hammer Tiotropium (Spiriva): mechanistical considerations and clinical profile in obstructive lung disease Life Sci 64 1999 457 464
-
(1999)
Life Sci
, vol.64
, pp. 457-464
-
-
Disse, B.1
Speck, G.A.2
Rominger, K.L.3
Witek, Jr.T.J.4
Hammer, R.5
-
14
-
-
33644763963
-
Anticholinergic agents in asthma and COPD
-
N.J. Gross Anticholinergic agents in asthma and COPD Eur J Pharmacol 533 2006 36 39
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 36-39
-
-
Gross, N.J.1
-
15
-
-
0031865167
-
The effect of adding ipratropium bromide to salbutamol in the treatment of acute asthma: A pooled analysis of three trials
-
S.F. Lanes, J.E. Garrett, C.E. Wentworth III, J.M. Fitzgerald, and J.P. Karpel The effect of adding ipratropium bromide to salbutamol in the treatment of acute asthma: a pooled analysis of three trials Chest 114 1998 365 372
-
(1998)
Chest
, vol.114
, pp. 365-372
-
-
Lanes, S.F.1
Garrett, J.E.2
Wentworth Iii, C.E.3
Fitzgerald, J.M.4
Karpel, J.P.5
-
17
-
-
0028814085
-
2-Adrenoceptor activation augments acetylcholine release from tracheal parasympathetic nerves
-
2- Adrenoceptor activation augments acetylcholine release from tracheal parasympathetic nerves Am J Physiol 268 1995 L950 L956
-
(1995)
Am J Physiol
, vol.268
-
-
Zhang, X.Y.1
Olszewski, M.A.2
Robinson, N.E.3
-
21
-
-
0028985618
-
Antagonism of β-adrenoceptor-mediated relaxations of human bronchial smooth muscle by carbachol
-
N. Watson, H. Magnussen, and K.F. Rabe Antagonism of β-adrenoceptor- mediated relaxations of human bronchial smooth muscle by carbachol Eur J Pharmacol 275 1995 307 310
-
(1995)
Eur J Pharmacol
, vol.275
, pp. 307-310
-
-
Watson, N.1
Magnussen, H.2
Rabe, K.F.3
-
22
-
-
0036833604
-
2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus
-
2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus Am J Physiol Lung Cell Mol Physiol 283 2002 L1125 L1132
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Sarria, B.1
Naline, E.2
Zhang, Y.3
Cortijo, J.4
Molimard, M.5
Moreau, J.6
Therond, P.7
Advenier, C.8
Morcillo, E.J.9
-
23
-
-
0030005408
-
Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle
-
H. Hakonarson, D.J. Herrick, P.G. Serrano, and M.M. Grunstein Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle J Clin Invest 97 1996 2593 2600
-
(1996)
J Clin Invest
, vol.97
, pp. 2593-2600
-
-
Hakonarson, H.1
Herrick, D.J.2
Serrano, P.G.3
Grunstein, M.M.4
-
24
-
-
84863121246
-
G protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma
-
G. Nino, A. Hu, J.S. Grunstein, J. McDonough, P.A. Kreiger, M.B. Josephson, J.K. Choi, and M.M. Grunstein G protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma PLoS ONE 7 2012 e32078
-
(2012)
PLoS ONE
, vol.7
, pp. 32078
-
-
Nino, G.1
Hu, A.2
Grunstein, J.S.3
McDonough, J.4
Kreiger, P.A.5
Josephson, M.B.6
Choi, J.K.7
Grunstein, M.M.8
-
25
-
-
0025183653
-
Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by β-adrenoceptor agonists
-
R.G. Van Amsterdam, H. Meurs, R.E. Ten Berge, N.C. Veninga, F. Brouwer, and J. Zaagsma Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by β-adrenoceptor agonists Am Rev Respir Dis 142 1990 1124 1128
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 1124-1128
-
-
Van Amsterdam, R.G.1
Meurs, H.2
Ten Berge, R.E.3
Veninga, N.C.4
Brouwer, F.5
Zaagsma, J.6
-
26
-
-
20344402041
-
Potentiation of β-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C
-
M. Boterman, C.R. Elzinga, D. Wagemakers, P.B. Eppens, J. Zaagsma, and H. Meurs Potentiation of β-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C Eur J Pharmacol 516 2005 85 92
-
(2005)
Eur J Pharmacol
, vol.516
, pp. 85-92
-
-
Boterman, M.1
Elzinga, C.R.2
Wagemakers, D.3
Eppens, P.B.4
Zaagsma, J.5
Meurs, H.6
-
27
-
-
0028009707
-
Modulation of airway smooth muscle β-adrenoceptor function by a muscarinic agonist
-
B.M. Grandordy, J.C. Mak, and P.J. Barnes Modulation of airway smooth muscle β-adrenoceptor function by a muscarinic agonist Life Sci 54 1994 185 191
-
(1994)
Life Sci
, vol.54
, pp. 185-191
-
-
Grandordy, B.M.1
Mak, J.C.2
Barnes, P.J.3
-
29
-
-
0030296744
-
G protein-coupled receptors: Heterologous regulation of homologous desensitization and its implications
-
T.T. Chuang, L. Iacovelli, M. Sallese, and A. De Blasi G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications Trends Pharmacol Sci 17 1996 416 421
-
(1996)
Trends Pharmacol Sci
, vol.17
, pp. 416-421
-
-
Chuang, T.T.1
Iacovelli, L.2
Sallese, M.3
De Blasi, A.4
-
30
-
-
84863524497
-
The bronchoprotective effect of olodaterol against histamine is synergistically enhanced and prolonged by tiotropium
-
M. Smit, A.B. Zuidhof, I.S. Bos, H. Maarsingh, R. Gosens, J. Zaagsma, and H. Meurs The bronchoprotective effect of olodaterol against histamine is synergistically enhanced and prolonged by tiotropium Am J Respir Crit Care Med 183 2011 A1379
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1379
-
-
Smit, M.1
Zuidhof, A.B.2
Bos, I.S.3
Maarsingh, H.4
Gosens, R.5
Zaagsma, J.6
Meurs, H.7
-
31
-
-
84873139771
-
Acute reversal of allergen-induced airway hyperresponsiveness (AHR) by olodaterol is synergistically enhanced by tiotropium bromide
-
M. Smit, A.B. Zuidhof, I.S. Bos, H. Maarsingh, R. Gosens, J. Zaagsma, and H. Meurs Acute reversal of allergen-induced airway hyperresponsiveness (AHR) by olodaterol is synergistically enhanced by tiotropium bromide Eur Respir J 38 Suppl 55 2011 306S
-
(2011)
Eur Respir J
, vol.38
, Issue.SUPPL. 55
-
-
Smit, M.1
Zuidhof, A.B.2
Bos, I.S.3
Maarsingh, H.4
Gosens, R.5
Zaagsma, J.6
Meurs, H.7
-
32
-
-
84894023715
-
Protection against allergen-induced airway hyperresponsiveness (AHR) by olodaterol in guinea pigs is synergistically enhanced by tiotropium
-
M. Smit, A.B. Zuidhof, I.S. Bos, H. Maarsingh, R. Gosens, J. Zaagsma, and H. Meurs Protection against allergen-induced airway hyperresponsiveness (AHR) by olodaterol in guinea pigs is synergistically enhanced by tiotropium Eur Respir J 40 Suppl 56 2012 379S
-
(2012)
Eur Respir J
, vol.40
, Issue.SUPPL. 56
-
-
Smit, M.1
Zuidhof, A.B.2
Bos, I.S.3
Maarsingh, H.4
Gosens, R.5
Zaagsma, J.6
Meurs, H.7
-
33
-
-
33846923601
-
2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs
-
2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs Pulm Pharmacol Ther 20 2007 250 257
-
(2007)
Pulm Pharmacol Ther
, vol.20
, pp. 250-257
-
-
Rossoni, G.1
Manfredi, B.2
Razzetti, R.3
Civelli, M.4
Berti, F.5
-
34
-
-
0036907527
-
2-agonists on resident and infiltrating inflammatory cells
-
2-agonists on resident and infiltrating inflammatory cells J Allergy Clin Immunol 110 2002 S282 S290
-
(2002)
J Allergy Clin Immunol
, vol.110
-
-
Johnson, M.1
-
35
-
-
79961173346
-
2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts
-
2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts Naunyn Schmiedebergs Arch Pharmacol 384 2011 133 145
-
(2011)
Naunyn Schmiedebergs Arch Pharmacol
, vol.384
, pp. 133-145
-
-
Lamyel, F.1
Warnken-Uhlich, M.2
Seemann, W.K.3
Mohr, K.4
Kostenis, E.5
Ahmedat, A.S.6
Smit, M.7
Gosens, R.8
Meurs, H.9
Miller-Larsson, A.10
Racké, K.11
-
36
-
-
0023192598
-
Regulation of the β-receptor-adenylate cyclase system in lymphocytes of allergic patients with asthma: Possible role for protein kinase C in allergen-induced nonspecific refractoriness of adenylate cyclase
-
H. Meurs, H.F. Kauffman, G.H. Koëter, A. Timmermans, and K. de Vries Regulation of the β-receptor-adenylate cyclase system in lymphocytes of allergic patients with asthma: possible role for protein kinase C in allergen-induced nonspecific refractoriness of adenylate cyclase J Allergy Clin Immunol 80 1987 326 339
-
(1987)
J Allergy Clin Immunol
, vol.80
, pp. 326-339
-
-
Meurs, H.1
Kauffman, H.F.2
Koëter, G.H.3
Timmermans, A.4
De Vries, K.5
-
37
-
-
84860350181
-
2 long-acting and anticholinergic drugs control TGF-β1-mediated neutrophilic inflammation in COPD
-
2 long-acting and anticholinergic drugs control TGF-β1-mediated neutrophilic inflammation in COPD Biochim Biophys Acta 1822 2012 1079 1089
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1079-1089
-
-
Profita, M.1
Bonanno, A.2
Montalbano, A.M.3
Albano, G.D.4
Riccobono, L.5
Siena, L.6
Ferraro, M.7
Casarosa, P.8
Pieper, M.P.9
Gjomarkaj, M.10
-
38
-
-
38449113726
-
Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: A comparison
-
I.S. Bos, R. Gosens, A.B. Zuidhof, D. Schaafsma, A.J. Halayko, H. Meurs, and J. Zaagsma Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison Eur Respir J 30 2007 653 661
-
(2007)
Eur Respir J
, vol.30
, pp. 653-661
-
-
Bos, I.S.1
Gosens, R.2
Zuidhof, A.B.3
Schaafsma, D.4
Halayko, A.J.5
Meurs, H.6
Zaagsma, J.7
-
39
-
-
77954357471
-
Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma
-
S. Ohta, N. Oda, T. Yokoe, A. Tanaka, Y. Yamamoto, Y. Watanabe, K. Minoguchi, T. Ohnishi, T. Hirose, H. Nagase, K. Ohta, and M. Adachi Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma Clin Exp Allergy 40 2010 1266 1275
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 1266-1275
-
-
Ohta, S.1
Oda, N.2
Yokoe, T.3
Tanaka, A.4
Yamamoto, Y.5
Watanabe, Y.6
Minoguchi, K.7
Ohnishi, T.8
Hirose, T.9
Nagase, H.10
Ohta, K.11
Adachi, M.12
-
40
-
-
78049265848
-
Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation
-
G. Damera, M. Jiang, H. Zhao, H.W. Fogle, W.F. Jester, J. Freire, and R.A. Panettieri Jr. Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation Eur J Pharmacol 649 2010 349 353
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 349-353
-
-
Damera, G.1
Jiang, M.2
Zhao, H.3
Fogle, H.W.4
Jester, W.F.5
Freire, J.6
Panettieri, Jr.R.A.7
-
41
-
-
79952534622
-
3 muscarinic receptor antagonist bencycloquidium bromide attenuates allergic airway inflammation, hyperresponsiveness and remodeling in mice
-
3 muscarinic receptor antagonist bencycloquidium bromide attenuates allergic airway inflammation, hyperresponsiveness and remodeling in mice Eur J Pharmacol 655 2011 83 90
-
(2011)
Eur J Pharmacol
, vol.655
, pp. 83-90
-
-
Cao, R.1
Dong, X.W.2
Jiang, J.X.3
Yan, X.F.4
He, J.S.5
Deng, Y.M.6
Li, F.F.7
Bao, M.J.8
Xie, Y.C.9
Chen, X.P.10
Xie, Q.M.11
-
42
-
-
77953123408
-
Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD
-
L. Wollin, and M.P. Pieper Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD Pulm Pharmacol Ther 23 2010 345 354
-
(2010)
Pulm Pharmacol Ther
, vol.23
, pp. 345-354
-
-
Wollin, L.1
Pieper, M.P.2
-
43
-
-
80052940501
-
Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD
-
T. Pera, A.B. Zuidhof, J. Valadas, M. Smit, R.G. Schoemaker, R. Gosens, H. Maarsingh, J. Zaagsma, and H. Meurs Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD Eur Respir J 38 2011 789 796
-
(2011)
Eur Respir J
, vol.38
, pp. 789-796
-
-
Pera, T.1
Zuidhof, A.B.2
Valadas, J.3
Smit, M.4
Schoemaker, R.G.5
Gosens, R.6
Maarsingh, H.7
Zaagsma, J.8
Meurs, H.9
-
44
-
-
0031957332
-
Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity
-
S. Koyama, E. Sato, H. Nomura, K. Kubo, S. Nagai, and T. Izumi Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity J Appl Physiol 84 1998 1528 1534
-
(1998)
J Appl Physiol
, vol.84
, pp. 1528-1534
-
-
Koyama, S.1
Sato, E.2
Nomura, H.3
Kubo, K.4
Nagai, S.5
Izumi, T.6
-
45
-
-
39149132101
-
Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism
-
M. Profita, A. Bonanno, L. Siena, M. Ferraro, A.M. Montalbano, F. Pompeo, L. Riccobono, M.P. Pieper, and M. Gjomarkaj Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism Eur J Pharmacol 582 2008 145 153
-
(2008)
Eur J Pharmacol
, vol.582
, pp. 145-153
-
-
Profita, M.1
Bonanno, A.2
Siena, L.3
Ferraro, M.4
Montalbano, A.M.5
Pompeo, F.6
Riccobono, L.7
Pieper, M.P.8
Gjomarkaj, M.9
-
46
-
-
73249148900
-
3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells
-
3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells Eur Respir J 34 2009 1436 1443
-
(2009)
Eur Respir J
, vol.34
, pp. 1436-1443
-
-
Gosens, R.1
Rieks, D.2
Meurs, H.3
Ninaber, D.K.4
Rabe, K.F.5
Nanninga, J.6
Kolahian, S.7
Halayko, A.J.8
Hiemstra, P.S.9
Zuyderduyn, S.10
-
47
-
-
34748819974
-
Tiotropium suppresses acetylcholine-induced release of chemotactic mediators in vitro
-
F. Buhling, N. Lieder, U.C. Kuhlmann, N. Waldburg, and T. Welte Tiotropium suppresses acetylcholine-induced release of chemotactic mediators in vitro Respir Med 101 2007 2386 2394
-
(2007)
Respir Med
, vol.101
, pp. 2386-2394
-
-
Buhling, F.1
Lieder, N.2
Kuhlmann, U.C.3
Waldburg, N.4
Welte, T.5
-
48
-
-
79951951764
-
Inhibition of granulocyte migration by tiotropium bromide
-
G. Vacca, W.J. Randerath, and A. Gillissen Inhibition of granulocyte migration by tiotropium bromide Respir Res 12 2011 24
-
(2011)
Respir Res
, vol.12
, pp. 24
-
-
Vacca, G.1
Randerath, W.J.2
Gillissen, A.3
-
49
-
-
84857089767
-
Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma
-
K.S. Buels, D.B. Jacoby, and A.D. Fryer Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma Br J Pharmacol 165 2012 1501 1514
-
(2012)
Br J Pharmacol
, vol.165
, pp. 1501-1514
-
-
Buels, K.S.1
Jacoby, D.B.2
Fryer, A.D.3
-
50
-
-
26944437890
-
4 production and neutrophilic inflammation in COPD patients
-
4 production and neutrophilic inflammation in COPD patients Allergy 60 2005 1361 1369
-
(2005)
Allergy
, vol.60
, pp. 1361-1369
-
-
Profita, M.1
Giorgi, R.D.2
Sala, A.3
Bonanno, A.4
Riccobono, L.5
Mirabella, F.6
Gjomarkaj, M.7
Bonsignore, G.8
Bousquet, J.9
Vignola, A.M.10
-
51
-
-
84856428464
-
In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD
-
M. Profita, L. Riccobono, A.M. Montalbano, A. Bonanno, M. Ferraro, G.D. Albano, S. Gerbino, P. Casarosa, M.P. Pieper, and M. Gjomarkaj In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD Immunobiology 217 2012 345 353
-
(2012)
Immunobiology
, vol.217
, pp. 345-353
-
-
Profita, M.1
Riccobono, L.2
Montalbano, A.M.3
Bonanno, A.4
Ferraro, M.5
Albano, G.D.6
Gerbino, S.7
Casarosa, P.8
Pieper, M.P.9
Gjomarkaj, M.10
-
52
-
-
84879092900
-
Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice
-
doi:1183/09031936.00112412, in press
-
L.E. Kistemaker, I.S. Bos, M.N. Hylkema, M.C. Nawijn, P.S. Hiemstra, J. Wess, H. Meurs, H.A. Kerstjens, and R. Gosens Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice Eur Respir J 2013 doi:1183/09031936.00112412, in press
-
(2013)
Eur Respir J
-
-
Kistemaker, L.E.1
Bos, I.S.2
Hylkema, M.N.3
Nawijn, M.C.4
Hiemstra, P.S.5
Wess, J.6
Meurs, H.7
Kerstjens, H.A.8
Gosens, R.9
-
53
-
-
0035891664
-
Remodeling in asthma and chronic obstructive lung disease
-
P.K. Jeffery Remodeling in asthma and chronic obstructive lung disease Am J Respir Crit Care Med 164 2001 S28 S38
-
(2001)
Am J Respir Crit Care Med
, vol.164
-
-
Jeffery, P.K.1
-
54
-
-
18644380685
-
Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling
-
R. Gosens, I.S. Bos, J. Zaagsma, and H. Meurs Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling Am J Respir Crit Care Med 171 2005 1096 1102
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1096-1102
-
-
Gosens, R.1
Bos, I.S.2
Zaagsma, J.3
Meurs, H.4
-
55
-
-
33845397124
-
Muscarinic receptors mediate stimulation of human lung fibroblast proliferation
-
S. Matthiesen, A. Bahulayan, S. Kempkens, S. Haag, M. Fuhrmann, C. Stichnote, U.R. Juergens, and K. Racké Muscarinic receptors mediate stimulation of human lung fibroblast proliferation Am J Respir Cell Mol Biol 35 2006 621 627
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 621-627
-
-
Matthiesen, S.1
Bahulayan, A.2
Kempkens, S.3
Haag, S.4
Fuhrmann, M.5
Stichnote, C.6
Juergens, U.R.7
Racké, K.8
-
56
-
-
58149376396
-
Muscarinic receptors mediate stimulation of collagen synthesis in human lung fibroblasts
-
S. Haag, S. Matthiesen, U.R. Juergens, and K. Racké Muscarinic receptors mediate stimulation of collagen synthesis in human lung fibroblasts Eur Respir J 32 2008 555 562
-
(2008)
Eur Respir J
, vol.32
, pp. 555-562
-
-
Haag, S.1
Matthiesen, S.2
Juergens, U.R.3
Racké, K.4
-
57
-
-
0033787918
-
Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle
-
V.P. Krymskaya, M.J. Orsini, A.J. Eszterhas, K.C. Brodbeck, J.L. Benovic, R.A. Panettieri Jr., and R.B. Penn Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle Am J Respir Cell Mol Biol 23 2000 546 554
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 546-554
-
-
Krymskaya, V.P.1
Orsini, M.J.2
Eszterhas, A.J.3
Brodbeck, K.C.4
Benovic, J.L.5
Panettieri, Jr.R.A.6
Penn, R.B.7
-
59
-
-
36348937450
-
Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation
-
R. Gosens, G. Dueck, E. Rector, R.O. Nunes, W.T. Gerthoffer, H. Unruh, J. Zaagsma, H. Meurs, and A.J. Halayko Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation Am J Physiol Lung Cell Mol Physiol 293 2007 L1348 L1358
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Gosens, R.1
Dueck, G.2
Rector, E.3
Nunes, R.O.4
Gerthoffer, W.T.5
Unruh, H.6
Zaagsma, J.7
Meurs, H.8
Halayko, A.J.9
-
61
-
-
74849084373
-
Airway structural components drive airway smooth muscle remodeling in asthma
-
B.G. Dekkers, H. Maarsingh, H. Meurs, and R. Gosens Airway structural components drive airway smooth muscle remodeling in asthma Proc Am Thorac Soc 6 2009 683 692
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 683-692
-
-
Dekkers, B.G.1
Maarsingh, H.2
Meurs, H.3
Gosens, R.4
-
62
-
-
84867190302
-
Muscarinic receptor stimulation augments TGF-β1-induced contractile protein expression by airway smooth muscle cells
-
T.A. Oenema, M. Smit, L. Smedinga, K. Racké, A.J. Halayko, H. Meurs, and R. Gosens Muscarinic receptor stimulation augments TGF-β1-induced contractile protein expression by airway smooth muscle cells Am J Physiol Lung Cell Mol Physiol 303 2012 L589 L5897
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Oenema, T.A.1
Smit, M.2
Smedinga, L.3
Racké, K.4
Halayko, A.J.5
Meurs, H.6
Gosens, R.7
-
63
-
-
84857444788
-
Aclidinium inhibits human lung fibroblast to myofibroblast transition
-
J. Milara, A. Serrano, T. Peiro, A. Gavalda, M. Miralpeix, E.J. Morcillo, and J. Cortijo Aclidinium inhibits human lung fibroblast to myofibroblast transition Thorax 67 2012 229 237
-
(2012)
Thorax
, vol.67
, pp. 229-237
-
-
Milara, J.1
Serrano, A.2
Peiro, T.3
Gavalda, A.4
Miralpeix, M.5
Morcillo, E.J.6
Cortijo, J.7
-
64
-
-
37249044357
-
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
-
P.J. Wipff, D.B. Rifkin, J.J. Meister, and B. Hinz Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix J Cell Biol 179 2007 1311 1323
-
(2007)
J Cell Biol
, vol.179
, pp. 1311-1323
-
-
Wipff, P.J.1
Rifkin, D.B.2
Meister, J.J.3
Hinz, B.4
-
65
-
-
82755189233
-
Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma
-
A.L. Tatler, A.E. John, L. Jolly, A. Habgood, J. Porte, C. Brightling, A.J. Knox, L. Pang, D. Sheppard, X. Huang, and G. Jenkins Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma J Immunol 187 2011 6094 6107
-
(2011)
J Immunol
, vol.187
, pp. 6094-6107
-
-
Tatler, A.L.1
John, A.E.2
Jolly, L.3
Habgood, A.4
Porte, J.5
Brightling, C.6
Knox, A.J.7
Pang, L.8
Sheppard, D.9
Huang, X.10
Jenkins, G.11
-
66
-
-
52649100121
-
Airway smooth muscle cell tone amplifies contractile function in the presence of chronic cyclic strain
-
N.J. Fairbank, S.C. Connolly, J.D. Mackinnon, K. Wehry, L. Deng, and G.N. Maksym Airway smooth muscle cell tone amplifies contractile function in the presence of chronic cyclic strain Am J Physiol Lung Cell Mol Physiol 295 2008 L479 L488
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Fairbank, N.J.1
Connolly, S.C.2
Mackinnon, J.D.3
Wehry, K.4
Deng, L.5
Maksym, G.N.6
-
67
-
-
79957512933
-
Effect of bronchoconstriction on airway remodeling in asthma
-
C.L. Grainge, L.C. Lau, J.A. Ward, V. Dulay, G. Lahiff, S. Wilson, S. Holgate, D.E. Davies, and P.H. Howarth Effect of bronchoconstriction on airway remodeling in asthma N Engl J Med 364 2011 2006 2015
-
(2011)
N Engl J Med
, vol.364
, pp. 2006-2015
-
-
Grainge, C.L.1
Lau, L.C.2
Ward, J.A.3
Dulay, V.4
Lahiff, G.5
Wilson, S.6
Holgate, S.7
Davies, D.E.8
Howarth, P.H.9
-
68
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
D.P. Tashkin, B. Celli, S. Senn, D. Burkhart, S. Kesten, S. Menjoge, and M. Decramer A 4-year trial of tiotropium in chronic obstructive pulmonary disease N Engl J Med 359 2008 1543 1554
-
(2008)
N Engl J Med
, vol.359
, pp. 1543-1554
-
-
Tashkin, D.P.1
Celli, B.2
Senn, S.3
Burkhart, D.4
Kesten, S.5
Menjoge, S.6
Decramer, M.7
-
69
-
-
70349547108
-
Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): A prespecified subgroup analysis of a randomised controlled trial
-
M. Decramer, B. Celli, S. Kesten, T. Lystig, S. Mehra, and D.P. Tashkin Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial Lancet 374 2009 1171 1178
-
(2009)
Lancet
, vol.374
, pp. 1171-1178
-
-
Decramer, M.1
Celli, B.2
Kesten, S.3
Lystig, T.4
Mehra, S.5
Tashkin, D.P.6
-
70
-
-
77957157119
-
COPD in young patients: A pre-specified analysis of the four-year trial of tiotropium (UPLIFT)
-
A.H. Morice, B. Celli, S. Kesten, T. Lystig, D. Tashkin, and M. Decramer COPD in young patients: a pre-specified analysis of the four-year trial of tiotropium (UPLIFT) Respir Med 104 2010 1659 1667
-
(2010)
Respir Med
, vol.104
, pp. 1659-1667
-
-
Morice, A.H.1
Celli, B.2
Kesten, S.3
Lystig, T.4
Tashkin, D.5
Decramer, M.6
-
71
-
-
37849014833
-
Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD
-
D.J. Powrie, T.M. Wilkinson, G.C. Donaldson, P. Jones, K. Scrine, K. Viel, S. Kesten, and J.A. Wedzicha Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD Eur Respir J 30 2007 472 478
-
(2007)
Eur Respir J
, vol.30
, pp. 472-478
-
-
Powrie, D.J.1
Wilkinson, T.M.2
Donaldson, G.C.3
Jones, P.4
Scrine, K.5
Viel, K.6
Kesten, S.7
Wedzicha, J.A.8
-
72
-
-
77957768543
-
Tiotropium bromide step-up therapy for adults with uncontrolled asthma
-
S.P. Peters, S.J. Kunselman, N. Icitovic, W.C. Moore, R. Pascual, B.T. Ameredes, H.A. Boushey, W.J. Calhoun, M. Castro, R.M. Cherniack, T. Craig, L. Denlinger, L.L. Engle, E.A. DiMango, J.V. Fahy, E. Israel, N. Jarjour, S.D. Kazani, M. Kraft, S.C. Lazarus, R.F. Lemanske Jr., N. Lugogo, R.J. Martin, D.A. Meyers, J. Ramsdell, C.A. Sorkness, E.R. Sutherland, S.J. Szefler, S.I. Wasserman, M.J. Walter, M.E. Wechsler, V.M. Chinchilli, and E.R. Bleecker Tiotropium bromide step-up therapy for adults with uncontrolled asthma N Engl J Med 363 2010 1715 1726
-
(2010)
N Engl J Med
, vol.363
, pp. 1715-1726
-
-
Peters, S.P.1
Kunselman, S.J.2
Icitovic, N.3
Moore, W.C.4
Pascual, R.5
Ameredes, B.T.6
Boushey, H.A.7
Calhoun, W.J.8
Castro, M.9
Cherniack, R.M.10
Craig, T.11
Denlinger, L.12
Engle, L.L.13
Dimango, E.A.14
Fahy, J.V.15
Israel, E.16
Jarjour, N.17
Kazani, S.D.18
Kraft, M.19
Lazarus, S.C.20
Lemanske, Jr.R.F.21
Lugogo, N.22
Martin, R.J.23
Meyers, D.A.24
Ramsdell, J.25
Sorkness, C.A.26
Sutherland, E.R.27
Szefler, S.J.28
Wasserman, S.I.29
Walter, M.J.30
Wechsler, M.E.31
Chinchilli, V.M.32
Bleecker, E.R.33
more..
-
73
-
-
79960973276
-
Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma
-
E.D. Bateman, O. Kornmann, P. Schmidt, A. Pivovarova, M. Engel, and L.M. Fabbri Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma J Allergy Clin Immunol 128 2011 315 322
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 315-322
-
-
Bateman, E.D.1
Kornmann, O.2
Schmidt, P.3
Pivovarova, A.4
Engel, M.5
Fabbri, L.M.6
-
74
-
-
79961016525
-
Tiotropium improves lung function in patients with severe uncontrolled asthma: A randomized controlled trial
-
H.A. Kerstjens, B. Disse, W. Schroder-Babo, T.A. Bantje, M. Gahlemann, R. Sigmund, M. Engel, and J.A. Van Noord Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trial J Allergy Clin Immunol 128 2011 308 314
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 308-314
-
-
Kerstjens, H.A.1
Disse, B.2
Schroder-Babo, W.3
Bantje, T.A.4
Gahlemann, M.5
Sigmund, R.6
Engel, M.7
Van Noord, J.A.8
-
75
-
-
84866758536
-
Tiotropium in asthma poorly controlled with standard combination therapy
-
H.A. Kerstjens, M. Engel, R. Dahl, P. Paggiaro, E. Beck, M. Vandewalker, R. Sigmund, W. Seibold, P. Moroni-Zentgraf, and E.D. Bateman Tiotropium in asthma poorly controlled with standard combination therapy N Engl J Med 367 2012 1198 1207
-
(2012)
N Engl J Med
, vol.367
, pp. 1198-1207
-
-
Kerstjens, H.A.1
Engel, M.2
Dahl, R.3
Paggiaro, P.4
Beck, E.5
Vandewalker, M.6
Sigmund, R.7
Seibold, W.8
Moroni-Zentgraf, P.9
Bateman, E.D.10
|