Tiotropium (spiriva(TM)): Mechanistical considerations and clinical profile in obstructive lung disease

Life Sciences

Volumn 64, Issue 6-7, 1999, Pages 457-464

  Disse, Bernd ^a   Speck, Georg A ^a   Rominger, Karl Ludwig ^a   Witek Jr , Theodore J ^a   Hammer, Rudolf ^a  

^a Corporate Medical Division ^*  (Germany)

Author keywords

Bronchodilator; COPD; Long acting antimuscarinic; Specific muscarinic; Tiotropium

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; IPRATROPIUM BROMIDE; METHACHOLINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; TIOTROPIUM BROMIDE; UNCLASSIFIED DRUG; BRONCHODILATING AGENT; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; SCOPOLAMINE DERIVATIVE; TIOTROPIUM;

ASTHMA; BRONCHODILATATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISSOCIATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG POTENCY; DRUG RECEPTOR BINDING; DYSPNEA; GEOMETRY; GUINEA PIG; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG FUNCTION TEST; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; ANIMAL; BINDING SITE; BLOOD; CELL MEMBRANE; DOSE RESPONSE; METABOLISM; REVIEW;

CAVIA PORCELLUS; SUS SCROFA;

ANIMALS; ASTHMA; BINDING SITES; BRONCHODILATOR AGENTS; CELL MEMBRANE; CLINICAL TRIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG DISEASES, OBSTRUCTIVE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; RECEPTORS, MUSCARINIC; SCOPOLAMINE DERIVATIVES;

EID: 0033534194     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00588-8     Document Type: Conference Paper

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