Tiotropium in asthma poorly controlled with standard combination therapy

New England Journal of Medicine

Volumn 367, Issue 13, 2012, Pages 1198-1207

  Kerstjens, Huib A M ^a   Engel, Michael ^b   Dahl, Ronald ^d   Paggiaro, Pierluigi ^e   Beck, Ekkehard ^c   Vandewalker, Mark ^f   Sigmund, Ralf ^b   Seibold, Wolfgang ^b   Moroni Zentgraf, Petra ^b   Bateman, Eric D ^g  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c Medical Department   (Germany)

^d AARHUS UNIVERSITY HOSPITAL   (Denmark)

^e UNIVERSITY HOSPITAL OF PISA   (Italy)

^f Clinical Research of the Ozarks   (United States)

^g UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; GLUCOCORTICOID; PLACEBO; TIOTROPIUM BROMIDE;

ADD ON THERAPY; ADULT; ALLERGIC RHINITIS; ARTHRALGIA; ARTICLE; ASTHMA; BACKACHE; BLOOD PRESSURE; BRAIN INFARCTION; BRONCHITIS; CONTROLLED STUDY; COUGHING; DIARRHEA; DISEASE EXACERBATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; DRUG SAFETY; DYSPHONIA; ECG ABNORMALITY; FEMALE; FORCED EXPIRATORY VOLUME; HEADACHE; HUMAN; HYPERTENSION; INFLUENZA; INSOMNIA; MAJOR CLINICAL STUDY; MALE; OROPHARYNX PAIN; PEAK EXPIRATORY FLOW; PNEUMONIA; PRIORITY JOURNAL; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION; RHINOPHARYNGITIS; RISK REDUCTION; SIDE EFFECT; SINUSITIS; TREATMENT OUTCOME; UPPER RESPIRATORY TRACT INFECTION; XEROSTOMIA;

EID: 84866758536     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1208606     Document Type: Article

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