The β 2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 384, Issue 2, 2011, Pages 133-145

  Lamyel, F ^a   Warnken Uhlich, M ^a   Seemann, W K ^a   Mohr, K ^a   Kostenis, E ^a   Ahmedat, A S ^a   Smit, M ^a,b   Gosens, R ^b   Meurs, H ^b   Miller Larsson, A ^c   Racké, Kurt ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Adrenoceptors; Airway remodelling; Collagen synthesis; Dynamic mass redistribution; Epac; Lung fibroblasts; Myofibroblast; Protein kinase C

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA 1 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; COLLAGEN; FORMOTEROL; MESSENGER RNA; OLODATEROL; THYMIDINE;

ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST CULTURE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG FIBROBLAST; LUNG FIBROSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADRENERGIC BETA-AGONISTS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE; CELL PROLIFERATION; COLLAGEN; CYCLIC AMP; FIBROBLASTS; HUMANS; MALE; PULMONARY FIBROSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ADRENERGIC, BETA-2; RNA;

EID: 79961173346     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0655-5     Document Type: Article

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