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Volumn 12, Issue 6, 2013, Pages 597-615

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma

Author keywords

dendritic cells; glioblastoma; immunosuppression; immunotherapy; vaccine

Indexed keywords

BEVACIZUMAB; BIOLOGICAL MARKER; CANCER VACCINE; CARBOXYMETHYLCELLULOSE POLYCYTIDYLIC POLYINOSINIC ACID POLYLYSINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DACLIZUMAB; DENDRITIC CELL VACCINE; ICT 107; IPILIMUMAB; PEPTIDE VACCINE; PLACEBO; RINDOPEPIMUT; SIPULEUCEL T; TEMOZOLOMIDE; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84879066269     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/erv.13.41     Document Type: Review
Times cited : (57)

References (238)
  • 2
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised Phase III study: 5-year analysis of the EORTCNCIC trial
    • European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group
    • Stupp R, Hegi ME, Mason WP et al.; European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised Phase III study: 5-year analysis of the EORTCNCIC trial. Lancet Oncol. 10(5), 459-466 (2009).
    • (2009) Lancet Oncol , vol.10 , Issue.5 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 4
    • 34047238978 scopus 로고    scopus 로고
    • The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme
    • DOI 10.1215/15228517-2006-025
    • Ballman KV, Buckner JC, Brown PD et al. The relationship between six-month progression-free survival and 12-month overall survival end points for Phase II trials in patients with glioblastoma multiforme. Neuro-oncology 9(1), 29-38 (2007). (Pubitemid 46543486)
    • (2007) Neuro-Oncology , vol.9 , Issue.1 , pp. 29-38
    • Ballman, K.V.1    Buckner, J.C.2    Brown, P.D.3    Giannini, C.4    Flynn, P.J.5    LaPlant, B.R.6    Jaeckle, K.A.7
  • 5
    • 44849138808 scopus 로고    scopus 로고
    • Progression-free survival: An important end point in evaluating therapy for recurrent high-grade gliomas
    • North American Brain Tumor Consortium
    • Lamborn KR, Yung WK, Chang SM et al.; North American Brain Tumor Consortium. Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas. Neuro-oncology 10(2), 162-170 (2008).
    • (2008) Neuro-oncology , vol.10 , Issue.2 , pp. 162-170
    • Lamborn, K.R.1    Yung, W.K.2    Chang, S.M.3
  • 7
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY, Kesari S. Malignant gliomas in adults. N. Engl. J. Med. 359(5), 492-507 (2008).
    • (2008) N. Engl. J. Med , vol.359 , Issue.5 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 8
    • 33644869659 scopus 로고    scopus 로고
    • Recent advances in the treatment of malignant astrocytoma
    • DOI 10.1200/JCO.2005.04.5302
    • Reardon DA, Rich JN, Friedman HS, Bigner DD. Recent advances in the treatment of malignant astrocytoma. J. Clin. Oncol. 24(8), 1253-1265 (2006). (Pubitemid 46622028)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.8 , pp. 1253-1265
    • Reardon, D.A.1    Rich, J.N.2    Friedman, H.S.3    Bigner, D.D.4
  • 9
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455(7216), 1061-1068 (2008).
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 10
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons DW, Jones S, Zhang X et al. An integrated genomic analysis of human glioblastoma multiforme. Science 321(5897), 1807-1812 (2008).
    • (2008) Science , vol.321 , Issue.5897 , pp. 1807-1812
    • Parsons, D.W.1    Jones, S.2    Zhang, X.3
  • 11
    • 77952108366 scopus 로고    scopus 로고
    • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
    • Cancer Genome Atlas Research Network
    • Noushmehr H, Weisenberger DJ, Diefes K et al.; Cancer Genome Atlas Research Network. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17(5), 510-522 (2010).
    • (2010) Cancer Cell , vol.17 , Issue.5 , pp. 510-522
    • Noushmehr, H.1    Weisenberger, D.J.2    Diefes, K.3
  • 12
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Cancer Genome Atlas Research Network
    • Verhaak RG, Hoadley KA, Purdom E et al.; Cancer Genome Atlas Research Network. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17(1), 98-110 (2010).
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3
  • 13
    • 33644820339 scopus 로고    scopus 로고
    • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
    • Phillips HS, Kharbanda S, Chen R et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9(3), 157-173 (2006).
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 157-173
    • Phillips, H.S.1    Kharbanda, S.2    Chen, R.3
  • 14
    • 79958766637 scopus 로고    scopus 로고
    • Molecular targeting of glioblastoma: Drug discovery and therapies
    • Bai RY, Staedtke V, Riggins GJ. Molecular targeting of glioblastoma: Drug discovery and therapies. Trends Mol. Med. 17(6), 301-312 (2011).
    • (2011) Trends Mol. Med , vol.17 , Issue.6 , pp. 301-312
    • Bai, R.Y.1    Staedtke, V.2    Riggins, G.J.3
  • 16
    • 84865310348 scopus 로고    scopus 로고
    • Molecular targeted therapy in recurrent glioblastoma: Current challenges and future directions
    • Patel M, Vogelbaum MA, Barnett GH, Jalali R, Ahluwalia MS. Molecular targeted therapy in recurrent glioblastoma: current challenges and future directions. Expert Opin. Investig. Drugs 21(9), 1247-1266 (2012).
    • (2012) Expert Opin. Investig. Drugs , vol.21 , Issue.9 , pp. 1247-1266
    • Patel, M.1    Vogelbaum, M.A.2    Barnett, G.H.3    Jalali, R.4    Ahluwalia, M.S.5
  • 17
    • 84865689994 scopus 로고    scopus 로고
    • New molecularly targeted therapies for glioblastoma multiforme
    • Polivka J Jr, Polivka J, Rohan V, Topolcan O, Ferda J. New molecularly targeted therapies for glioblastoma multiforme. Anticancer Res. 32(7), 2935-2946 (2012).
    • (2012) Anticancer Res , vol.32 , Issue.7 , pp. 2935-2946
    • Polivka Jr., J.1    Polivka, J.2    Rohan, V.3    Topolcan, O.4    Ferda, J.5
  • 18
    • 32944479646 scopus 로고    scopus 로고
    • Therapeutic advances in the treatment of glioblastoma: Rationale and potential role of targeted agents
    • DOI 10.1634/theoncologist.11-2-152
    • Reardon DA, Wen PY. Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agents. Oncologist 11(2), 152-164 (2006). (Pubitemid 43261762)
    • (2006) Oncologist , vol.11 , Issue.2 , pp. 152-164
    • Reardon, D.A.1    Wen, P.Y.2
  • 19
    • 67449095068 scopus 로고    scopus 로고
    • Targeting multiple kinases in glioblastoma multiforme
    • Sathornsumetee S, Reardon DA. Targeting multiple kinases in glioblastoma multiforme. Expert Opin. Investig. Drugs 18(3), 277-292 (2009).
    • (2009) Expert Opin. Investig. Drugs , vol.18 , Issue.3 , pp. 277-292
    • Sathornsumetee, S.1    Reardon, D.A.2
  • 21
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman HS, Prados MD, Wen PY et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J. Clin. Oncol. 27(28), 4733-4740 (2009).
    • (2009) J. Clin. Oncol , vol.27 , Issue.28 , pp. 4733-4740
    • Friedman, H.S.1    Prados, M.D.2    Wen, P.Y.3
  • 22
    • 59949083263 scopus 로고    scopus 로고
    • Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
    • Kreisl TN, Kim L, Moore K et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J. Clin. Oncol. 27(5), 740-745 (2009).
    • (2009) J. Clin. Oncol , vol.27 , Issue.5 , pp. 740-745
    • Kreisl, T.N.1    Kim, L.2    Moore, K.3
  • 23
    • 79953840934 scopus 로고    scopus 로고
    • A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma
    • Reardon DA, Turner S, Peters KB et al. A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma. J. Natl Compr. Canc. Netw. 9(4), 414-427 (2011).
    • (2011) J. Natl Compr. Canc. Netw , vol.9 , Issue.4 , pp. 414-427
    • Reardon, D.A.1    Turner, S.2    Peters, K.B.3
  • 24
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • IMPACT Study Investigators
    • Kantoff PW, Higano CS, Shore ND et al.; IMPACT Study Investigators. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363(5), 411-422 (2010).
    • (2010) N. Engl. J. Med , vol.363 , Issue.5 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 25
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363(8), 711-723 (2010).
    • (2010) N. Engl. J. Med , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 28
  • 29
    • 78651010946 scopus 로고
    • Immunity to homologous grafted skin; The fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye
    • Medawar PB. Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br. J. Exp. Pathol. 29(1), 58-69 (1948).
    • (1948) Br. J. Exp. Pathol , vol.29 , Issue.1 , pp. 58-69
    • Medawar, P.B.1
  • 31
    • 0032752574 scopus 로고    scopus 로고
    • Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation
    • DOI 10.1016/S0165-5728(99)00130-7, PII S0165572899001307
    • Harling-Berg CJ, Park TJ, Knopf PM. Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation. J. Neuroimmunol. 101(2), 111-127 (1999). (Pubitemid 29516453)
    • (1999) Journal of Neuroimmunology , vol.101 , Issue.2 , pp. 111-127
    • Harling-Berg, C.J.1    Park, J.T.2    Knopf, P.M.3
  • 32
    • 33751503037 scopus 로고    scopus 로고
    • T cells traffic from brain to cervical lymph nodes via the cribroid plate and the nasal mucosa
    • DOI 10.1189/jlb.0306176
    • Goldmann J, Kwidzinski E, Brandt C, Mahlo J, Richter D, Bechmann I. T cells traffic from brain to cervical lymph nodes via the cribroid plate and the nasal mucosa. J. Leukoc. Biol. 80(4), 797-801 (2006). (Pubitemid 44835898)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.4 , pp. 797-801
    • Goldmann, J.1    Kwidzinski, E.2    Brandt, C.3    Mahlo, J.4    Richter, D.5    Bechmann, I.6
  • 35
    • 0025981021 scopus 로고
    • T-lymphocyte entry into the central nervous system
    • Hickey WF, Hsu BL, Kimura H. T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 28(2), 254-260 (1991).
    • (1991) J. Neurosci. Res , vol.28 , Issue.2 , pp. 254-260
    • Hickey, W.F.1    Hsu, B.L.2    Kimura, H.3
  • 36
    • 0031091753 scopus 로고    scopus 로고
    • Regulation of Brain-Derived T Cells during Acute Central Nervous System Inflammation
    • Irani DN, Lin KI, Griffin DE. Regulation of brain-derived T cells during acute central nervous system inflammation. J. Immunol. 158(5), 2318-2326 (1997). (Pubitemid 127470017)
    • (1997) Journal of Immunology , vol.158 , Issue.5 , pp. 2318-2326
    • Irani, D.N.1    Lin, K.-I.2    Griffin, D.E.3
  • 37
    • 0142259710 scopus 로고    scopus 로고
    • Three or more routes for leukocyte migration into the central nervous system
    • DOI 10.1038/nri1130
    • Ransohoff RM, Kivisäkk P, Kidd G. Three or more routes for leukocyte migration into the central nervous system. Nat. Rev. Immunol. 3(7), 569-581 (2003). (Pubitemid 37328676)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.7 , pp. 569-581
    • Ransohoff, R.M.1    Kivisakk, P.2    Kidd, G.3
  • 38
    • 45849130520 scopus 로고    scopus 로고
    • Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain
    • Prins RM, Shu CJ, Radu CG et al. Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain. Cancer Immunol. Immunother. 57(9), 1279-1289 (2008).
    • (2008) Cancer Immunol. Immunother , vol.57 , Issue.9 , pp. 1279-1289
    • Prins, R.M.1    Shu, C.J.2    Radu, C.G.3
  • 40
    • 0029841918 scopus 로고    scopus 로고
    • Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the 'immunologically privileged' central nervous system
    • Sampson JH, Archer GE, Ashley DM et al. Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the 'immunologically privileged' central nervous system. Proc. Natl Acad. Sci. USA 93(19), 10399-10404 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.19 , pp. 10399-10404
    • Sampson, J.H.1    Archer, G.E.2    Ashley, D.M.3
  • 41
    • 34548807135 scopus 로고    scopus 로고
    • Brain microenvironment promotes the final functional maturation of tumor-specific effector CD8+ T cells
    • Masson F, Calzascia T, Di Berardino-Besson W, de Tribolet N, Dietrich PY, Walker PR. Brain microenvironment promotes the final functional maturation of tumor-specific effector CD8+ T cells. J. Immunol. 179(2), 845-853 (2007).
    • (2007) J. Immunol , vol.179 , Issue.2 , pp. 845-853
    • Masson, F.1    Calzascia, T.2    Di Berardino-Besson, W.3    De Tribolet, N.4    Dietrich, P.Y.5    Walker, P.R.6
  • 42
    • 3242658002 scopus 로고    scopus 로고
    • Microglia phagocytose alloreactive CTL-damaged 9L gliosarcoma cells
    • DOI 10.1016/j.jneuroim.2004.04.011, PII S0165572804001523
    • Kulprathipanja NV, Kruse CA. Microglia phagocytose alloreactive CTL-damaged 9L gliosarcoma cells. J. Neuroimmunol. 153(1-2), 76-82 (2004). (Pubitemid 38950929)
    • (2004) Journal of Neuroimmunology , vol.153 , Issue.1-2 , pp. 76-82
    • Kulprathipanja, N.V.1    Kruse, C.A.2
  • 43
    • 0032925357 scopus 로고    scopus 로고
    • Microglia stimulate naive T-cell differentiation without stimulating T- cell proliferation
    • DOI 10.1002/(SICI)1097-4547(19990101)55:1<127::AID-JNR14>3.0.CO;2-2
    • Carson MJ, Sutcliffe JG, Campbell IL. Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation. J. Neurosci. Res. 55(1), 127-134 (1999). (Pubitemid 29014418)
    • (1999) Journal of Neuroscience Research , vol.55 , Issue.1 , pp. 127-134
    • Carson, M.J.1    Sutcliffe, J.G.2    Campbell, I.L.3
  • 44
    • 0028964455 scopus 로고
    • The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions
    • De Simone R, Giampaolo A, Giometto B et al. The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions. J. Neuropathol. Exp. Neurol. 54(2), 175-187 (1995).
    • (1995) J. Neuropathol. Exp. Neurol , vol.54 , Issue.2 , pp. 175-187
    • De Simone, R.1    Giampaolo, A.2    Giometto, B.3
  • 45
    • 0032524997 scopus 로고    scopus 로고
    • Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation
    • Aloisi F, Ria F, Penna G, Adorini L. Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation. J. Immunol. 160(10), 4671-4680 (1998). (Pubitemid 28215299)
    • (1998) Journal of Immunology , vol.160 , Issue.10 , pp. 4671-4680
    • Aloisi, F.1    Ria, F.2    Penna, G.3    Adorini, L.4
  • 46
    • 0023949553 scopus 로고
    • Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
    • Hickey WF, Kimura H. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239(4837), 290-292 (1988). (Pubitemid 18061496)
    • (1988) Science , vol.239 , Issue.4837 , pp. 290-292
    • Hickey, W.F.1    Kimura, H.2
  • 47
    • 0024467217 scopus 로고
    • Microglial cells in human brain have phenotypic characteristics related to possible function as dendritic antigen presenting cells
    • Lowe J, MacLennan KA, Powe DG, Pound JD, Palmer JB. Microglial cells in human brain have phenotypic characteristics related to possible function as dendritic antigen presenting cells. J. Pathol. 159(2), 143-149 (1989). (Pubitemid 19257232)
    • (1989) Journal of Pathology , vol.159 , Issue.2 , pp. 143-149
    • Lowe, J.1    Maclennan, K.A.2    Powe, D.G.3    Pound, J.D.4    Palmer, J.B.5
  • 48
    • 0028558519 scopus 로고
    • Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigenpresenting cells
    • Ulvestad E, Williams K, Bjerkvig R, Tiekotter K, Antel J, Matre R. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigenpresenting cells. J. Leukoc. Biol. 56(6), 732-740 (1994).
    • (1994) J. Leukoc. Biol , vol.56 , Issue.6 , pp. 732-740
    • Ulvestad, E.1    Williams, K.2    Bjerkvig, R.3    Tiekotter, K.4    Antel, J.5    Matre, R.6
  • 49
    • 0027139705 scopus 로고
    • Microglia in the immune surveillance of the brain: Human microglia constitutively express HLA-DR molecules
    • DOI 10.1016/0165-5728(93)90191-Z
    • Gehrmann J, Banati RB, Kreutzberg GW. Microglia in the immune surveillance of the brain: human microglia constitutively express HLA-DR molecules. J. Neuroimmunol. 48(2), 189-198 (1993). (Pubitemid 24010174)
    • (1993) Journal of Neuroimmunology , vol.48 , Issue.2 , pp. 189-198
    • Gehrmann, J.1    Banati, R.B.2    Kreutzberg, G.W.3
  • 51
    • 34548555781 scopus 로고    scopus 로고
    • Expression of interleukin-13 receptor 2 in glioblastoma multiforme: Implications for targeted therapies
    • Jarboe JS, Johnson KR, Choi Y, Lonser RR, Park JK. Expression of interleukin-13 receptor 2 in glioblastoma multiforme: implications for targeted therapies. Cancer Res. 67(17), 7983-7986 (2007).
    • (2007) Cancer Res , vol.67 , Issue.17 , pp. 7983-7986
    • Jarboe, J.S.1    Johnson, K.R.2    Choi, Y.3    Lonser, R.R.4    Park, J.K.5
  • 52
    • 0025686126 scopus 로고
    • Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts
    • Bigner SH, Humphrey PA, Wong AJ et al. Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. Cancer Res. 50(24), 8017-8022 (1990).
    • (1990) Cancer Res , vol.50 , Issue.24 , pp. 8017-8022
    • Bigner, S.H.1    Humphrey, P.A.2    Wong, A.J.3
  • 53
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • DOI 10.1038/313144a0
    • Libermann TA, Nusbaum HR, Razon N et al. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313(5998), 144-147 (1985). (Pubitemid 15192341)
    • (1985) Nature , vol.313 , Issue.5998 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3
  • 56
    • 0032749913 scopus 로고    scopus 로고
    • Expression of the tumor-rejection antigen SART1 in brain tumors
    • Imaizumi T, Kuramoto T, Matsunaga K et al. Expression of the tumor-rejection antigen SART1 in brain tumors. Int. J. Cancer 83(6), 760-764 (1999).
    • (1999) Int. J. Cancer , vol.83 , Issue.6 , pp. 760-764
    • Imaizumi, T.1    Kuramoto, T.2    Matsunaga, K.3
  • 57
    • 0033049977 scopus 로고    scopus 로고
    • Expression of MAGE and GAGE in high-grade brain tumors: A potential target for specific immunotherapy and diagnostic markers
    • Scarcella DL, Chow CW, Gonzales MF, Economou C, Brasseur F, Ashley DM. Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers. Clin. Cancer Res. 5(2), 335-341 (1999). (Pubitemid 29085187)
    • (1999) Clinical Cancer Research , vol.5 , Issue.2 , pp. 335-341
    • Scarcella, D.L.1    Chow, C.W.2    Gonzales, M.F.3    Economou, C.4    Brasseur, F.5    Ashley, D.M.6
  • 58
    • 0036718859 scopus 로고    scopus 로고
    • Identification of a novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitope in a human glioma-associated antigen, interleukin 13 receptor α2 chain
    • Okano F, Storkus WJ, Chambers WH, Pollack IF, Okada H. Identification of a novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitope in a human glioma-associated antigen, interleukin 13 receptor 2 chain. Clin. Cancer Res. 8(9), 2851-2855 (2002). (Pubitemid 35025729)
    • (2002) Clinical Cancer Research , vol.8 , Issue.9 , pp. 2851-2855
    • Okano, F.1    Storkus, W.J.2    Chambers, W.H.3    Pollack, I.F.4    Okada, H.5
  • 59
    • 3142710121 scopus 로고    scopus 로고
    • HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells
    • DOI 10.1158/0008-5472.CAN-03-3504
    • Liu G, Ying H, Zeng G, Wheeler CJ, Black KL, Yu JS. HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells. Cancer Res. 64(14), 4980-4986 (2004). (Pubitemid 38924546)
    • (2004) Cancer Research , vol.64 , Issue.14 , pp. 4980-4986
    • Liu, G.1    Ying, H.2    Zeng, G.3    Wheeler, C.J.4    Black, K.L.5    Yu, J.S.6
  • 60
    • 3142692559 scopus 로고    scopus 로고
    • Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma
    • DOI 10.1158/0008-5472.CAN-03-3505
    • Yu JS, Liu G, Ying H, Yong WH, Black KL, Wheeler CJ. Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma. Cancer Res. 64(14), 4973-4979 (2004). (Pubitemid 38924545)
    • (2004) Cancer Research , vol.64 , Issue.14 , pp. 4973-4979
    • Yu, J.S.1    Liu, G.2    Ying, H.3    Yong, W.H.4    Black, K.L.5    Wheeler, C.J.6
  • 63
    • 0036626547 scopus 로고    scopus 로고
    • Pollack IF. 7-Hydroxystaurosporine-induced apoptosis in 9L glioma cells provides an effective antigen source for dendritic cells and yields a potent vaccine strategy in an intracranial glioma model
    • discussion 1334 2002
    • Witham TF, Erff ML, Okada H, Chambers WH, Pollack IF. 7-Hydroxystaurosporine-induced apoptosis in 9L glioma cells provides an effective antigen source for dendritic cells and yields a potent vaccine strategy in an intracranial glioma model. Neurosurgery 50(6), 1327-1334; discussion 1334 (2002).
    • Neurosurgery , vol.50 , Issue.6 , pp. 1327-1334
    • Witham, T.F.1    Erff, M.L.2    Okada, H.3    Chambers, W.H.4
  • 64
    • 0035165499 scopus 로고    scopus 로고
    • Dendritic cells pulsed with tumor extract-cationic liposome complex increase the induction of clytotoxic T lymphocytes in mouse brain tumor
    • DOI 10.1007/s002620100220
    • Aoki H, Mizuno M, Natsume A et al. Dendritic cells pulsed with tumor extract-cationic liposome complex increase the induction of cytotoxic T lymphocytes in mouse brain tumor. Cancer Immunol. Immunother. 50(9), 463-468 (2001). (Pubitemid 33079342)
    • (2001) Cancer Immunology, Immunotherapy , vol.50 , Issue.9 , pp. 463-468
    • Aoki, H.1    Mizuno, M.2    Natsume, A.3    Tsugawa, T.4    Tsujimura, K.5    Takahashi, T.6    Yoshida, J.7
  • 66
    • 0030808677 scopus 로고    scopus 로고
    • Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors
    • DOI 10.1084/jem.186.7.1177
    • Ashley DM, Faiola B, Nair S, Hale LP, Bigner DD, Gilboa E. Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors. J. Exp. Med. 186(7), 1177-1182 (1997). (Pubitemid 27441162)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.7 , pp. 1177-1182
    • Ashley, D.M.1    Faiola, B.2    Nair, S.3    Hale, L.P.4    Bigner, D.D.5    Gilboa, E.6
  • 67
    • 0029959095 scopus 로고    scopus 로고
    • Cure of established, intracerebral rat gliomas induced by therapeutic immunizations with tumor cells and purified APC or adjuvant IFN-γ treatment
    • Siesjö P, Visse E, Sjögren HO. Cure of established, intracerebral rat gliomas induced by therapeutic immunizations with tumor cells and purified APC or adjuvant IFN-treatment. J. Immunother. Emphasis Tumor Immunol. 19(5), 334-345 (1996). (Pubitemid 26398802)
    • (1996) Journal of Immunotherapy , vol.19 , Issue.5 , pp. 334-345
    • Siesjo, P.1    Visse, E.2    Sjogren, H.O.3
  • 69
    • 0142089462 scopus 로고    scopus 로고
    • Treatment of a patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides
    • Liau LM, Black KL, Martin NA et al. Treatment of a patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides. Case Report. Neurosurg. Focus 9(6), e8 (2000).
    • (2000) Case Report. Neurosurg. Focus , vol.9 , Issue.6
    • Liau, L.M.1    Black, K.L.2    Martin, N.A.3
  • 70
  • 75
    • 49649113879 scopus 로고    scopus 로고
    • Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme
    • De Vleeschouwer S, Fieuws S, Rutkowski S et al. Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme. Clin. Cancer Res. 14(10), 3098-3104 (2008).
    • (2008) Clin. Cancer Res , vol.14 , Issue.10 , pp. 3098-3104
    • De Vleeschouwer, S.1    Fieuws, S.2    Rutkowski, S.3
  • 76
    • 48649096955 scopus 로고    scopus 로고
    • Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients
    • Wheeler CJ, Black KL, Liu G et al. Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients. Cancer Res. 68(14), 5955-5964 (2008).
    • (2008) Cancer Res , vol.68 , Issue.14 , pp. 5955-5964
    • Wheeler, C.J.1    Black, K.L.2    Liu, G.3
  • 77
    • 79952711945 scopus 로고    scopus 로고
    • Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy
    • Prins RM, Soto H, Konkankit V et al. Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy. Clin. Cancer Res. 17(6), 1603-1615 (2011).
    • (2011) Clin. Cancer Res , vol.17 , Issue.6 , pp. 1603-1615
    • Prins, R.M.1    Soto, H.2    Konkankit, V.3
  • 78
    • 79955591522 scopus 로고    scopus 로고
    • Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy
    • Fadul CE, Fisher JL, Hampton TH et al. Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy. J. Immunother. 34(4), 382-389 (2011).
    • (2011) J. Immunother , vol.34 , Issue.4 , pp. 382-389
    • Fadul, C.E.1    Fisher, J.L.2    Hampton, T.H.3
  • 79
    • 84870985481 scopus 로고    scopus 로고
    • Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: Results of the HGG-2006 Phase I/II trial
    • Ardon H, Van Gool SW, Verschuere T et al. Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 Phase I/II trial. Cancer Immunol. Immunother. 61(11), 2033-2044 (2012).
    • (2012) Cancer Immunol. Immunother , vol.61 , Issue.11 , pp. 2033-2044
    • Ardon, H.1    Van Gool, S.W.2    Verschuere, T.3
  • 80
    • 77956061272 scopus 로고    scopus 로고
    • Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: A pilot study
    • Ardon H, Van Gool S, Lopes IS et al. Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: a pilot study. J. Neurooncol. 99(2), 261-272 (2010).
    • (2010) J. Neurooncol , vol.99 , Issue.2 , pp. 261-272
    • Ardon, H.1    Van Gool, S.2    Lopes, I.S.3
  • 81
    • 84871951211 scopus 로고    scopus 로고
    • Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein
    • Crane CA, Han SJ, Ahn B et al. Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein. Clin. Cancer Res. 19(1), 205-214 (2013).
    • (2013) Clin. Cancer Res , vol.19 , Issue.1 , pp. 205-214
    • Crane, C.A.1    Han, S.J.2    Ahn, B.3
  • 82
    • 79960379942 scopus 로고    scopus 로고
    • Cytotoxic immunotherapy strategies for cancer: Mechanisms and clinical development
    • Aguilar LK, Guzik BW, Aguilar-Cordova E. Cytotoxic immunotherapy strategies for cancer: mechanisms and clinical development. J. Cell. Biochem. 112(8), 1969-1977 (2011).
    • (2011) J. Cell. Biochem , vol.112 , Issue.8 , pp. 1969-1977
    • Aguilar, L.K.1    Guzik, B.W.2    Aguilar-Cordova, E.3
  • 83
    • 80053061789 scopus 로고    scopus 로고
    • Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma
    • Chiocca EA, Aguilar LK, Bell SD et al. Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. J. Clin. Oncol. 29(27), 3611-3619 (2011).
    • (2011) J. Clin. Oncol , vol.29 , Issue.27 , pp. 3611-3619
    • Chiocca, E.A.1    Aguilar, L.K.2    Bell, S.D.3
  • 84
    • 78449298442 scopus 로고    scopus 로고
    • Cancer stem cells in the central nervous system-a critical review
    • Prestegarden L, Enger P∅. Cancer stem cells in the central nervous system-a critical review. Cancer Res. 70(21), 8255-8258 (2010).
    • (2010) Cancer Res , vol.70 , Issue.21 , pp. 8255-8258
    • Prestegarden, L.1    Enger, P.2
  • 85
    • 46449115281 scopus 로고    scopus 로고
    • Stem cell-related 'self-renewal' signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
    • Murat A, Migliavacca E, Gorlia T et al. Stem cell-related 'self-renewal' signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J. Clin. Oncol. 26(18), 3015-3024 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.18 , pp. 3015-3024
    • Murat, A.1    Migliavacca, E.2    Gorlia, T.3
  • 87
    • 78049270536 scopus 로고    scopus 로고
    • Glioma cancer stem cells induce immunosuppressive macrophages/microglia
    • Wu A, Wei J, Kong LY et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro-oncology 12(11), 1113-1125 (2010).
    • (2010) Neuro-oncology , vol.12 , Issue.11 , pp. 1113-1125
    • Wu, A.1    Wei, J.2    Kong, L.Y.3
  • 88
    • 76049114698 scopus 로고    scopus 로고
    • Immunobiological characterization of cancer stem cells isolated from glioblastoma patients
    • Di Tomaso T, Mazzoleni S, Wang E et al. Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin. Cancer Res. 16(3), 800-813 (2010).
    • (2010) Clin. Cancer Res , vol.16 , Issue.3 , pp. 800-813
    • Di Tomaso, T.1    Mazzoleni, S.2    Wang, E.3
  • 89
    • 69249149701 scopus 로고    scopus 로고
    • Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens
    • Xu Q, Liu G, Yuan X et al. Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens. Stem Cells 27(8), 1734-1740 (2009).
    • (2009) Stem Cells , vol.27 , Issue.8 , pp. 1734-1740
    • Xu, Q.1    Liu, G.2    Yuan, X.3
  • 91
    • 0346995276 scopus 로고    scopus 로고
    • Immunotherapeutic Targeting of Shared Melanoma-Associated Antigens in a Murine Glioma Model
    • Prins RM, Odesa SK, Liau LM. Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model. Cancer Res. 63(23), 8487-8491 (2003). (Pubitemid 37549505)
    • (2003) Cancer Research , vol.63 , Issue.23 , pp. 8487-8491
    • Prins, R.M.1    Odesa, S.K.2    Liau, L.M.3
  • 92
    • 21344462768 scopus 로고    scopus 로고
    • Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy
    • DOI 10.1038/sj.onc.1208519
    • Liu G, Akasaki Y, Khong HT et al. Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy. Oncogene 24(33), 5226-5234 (2005). (Pubitemid 41192439)
    • (2005) Oncogene , vol.24 , Issue.33 , pp. 5226-5234
    • Liu, G.1    Akasaki, Y.2    Khong, H.T.3    Wheeler, C.J.4    Das, A.5    Black, K.L.6    Yu, J.S.7
  • 93
    • 0026548240 scopus 로고
    • Structural alterations of the epidermal growth factor receptor gene in human gliomas
    • Wong AJ, Ruppert JM, Bigner SH et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas. Proc. Natl Acad. Sci. USA 89(7), 2965-2969 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , Issue.7 , pp. 2965-2969
    • Wong, A.J.1    Ruppert, J.M.2    Bigner, S.H.3
  • 94
    • 0028800035 scopus 로고
    • Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors
    • Moscatello DK, Holgado-Madruga M, Godwin AK et al. Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors. Cancer Res. 55(23), 5536-5539 (1995).
    • (1995) Cancer Res , vol.55 , Issue.23 , pp. 5536-5539
    • Moscatello, D.K.1    Holgado-Madruga, M.2    Godwin, A.K.3
  • 95
    • 0028863853 scopus 로고
    • Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene
    • Batra SK, Castelino-Prabhu S, Wikstrand CJ et al. Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene. Cell Growth Differ. 6(10), 1251-1259 (1995).
    • (1995) Cell Growth Differ , vol.6 , Issue.10 , pp. 1251-1259
    • Batra, S.K.1    Castelino-Prabhu, S.2    Wikstrand, C.J.3
  • 100
    • 52649169692 scopus 로고    scopus 로고
    • Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas
    • Heimberger AB, Abou-Ghazal M, Reina-Ortiz C et al. Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas. Clin. Cancer Res. 14(16), 5166-5172 (2008).
    • (2008) Clin. Cancer Res , vol.14 , Issue.16 , pp. 5166-5172
    • Heimberger, A.B.1    Abou-Ghazal, M.2    Reina-Ortiz, C.3
  • 101
    • 53049089002 scopus 로고    scopus 로고
    • Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines
    • Schmittling RJ, Archer GE, Mitchell DA et al. Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines. J. Immunol. Methods 339(1), 74-81 (2008).
    • (2008) J. Immunol. Methods , vol.339 , Issue.1 , pp. 74-81
    • Schmittling, R.J.1    Archer, G.E.2    Mitchell, D.A.3
  • 102
    • 70350236627 scopus 로고    scopus 로고
    • An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme
    • Sampson JH, Archer GE, Mitchell DA et al. An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme. Mol. Cancer Ther. 8(10), 2773-2779 (2009).
    • (2009) Mol. Cancer Ther , vol.8 , Issue.10 , pp. 2773-2779
    • Sampson, J.H.1    Archer, G.E.2    Mitchell, D.A.3
  • 103
    • 78149254368 scopus 로고    scopus 로고
    • Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
    • Sampson JH, Heimberger AB, Archer GE et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J. Clin. Oncol. 28(31), 4722-4729 (2010).
    • (2010) J. Clin. Oncol , vol.28 , Issue.31 , pp. 4722-4729
    • Sampson, J.H.1    Heimberger, A.B.2    Archer, G.E.3
  • 104
    • 79955784386 scopus 로고    scopus 로고
    • Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma
    • Sampson JH, Aldape KD, Archer GE et al. Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma. Neuro-oncology 13(3), 324-333 (2011).
    • (2011) Neuro-oncology , vol.13 , Issue.3 , pp. 324-333
    • Sampson, J.H.1    Aldape, K.D.2    Archer, G.E.3
  • 105
    • 80051693219 scopus 로고    scopus 로고
    • Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide
    • NABTT CNS Consortium
    • Grossman SA, Ye X, Lesser G et al.; NABTT CNS Consortium. Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide. Clin. Cancer Res. 17(16), 5473-5480 (2011).
    • (2011) Clin. Cancer Res , vol.17 , Issue.16 , pp. 5473-5480
    • Grossman, S.A.1    Ye, X.2    Lesser, G.3
  • 106
    • 84862776855 scopus 로고    scopus 로고
    • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
    • Matsushita H, Vesely MD, Koboldt DC et al. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature 482(7385), 400-404 (2012).
    • (2012) Nature , vol.482 , Issue.7385 , pp. 400-404
    • Matsushita, H.1    Vesely, M.D.2    Koboldt, D.C.3
  • 107
    • 79951978155 scopus 로고    scopus 로고
    • Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma
    • Okada H, Kalinski P, Ueda R et al. Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {}-type 1 polarized dendritic cells and polyinosinic- polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma. J. Clin. Oncol. 29(3), 330-336 (2011).
    • (2011) J. Clin. Oncol , vol.29 , Issue.3 , pp. 330-336
    • Okada, H.1    Kalinski, P.2    Ueda, R.3
  • 108
    • 84872498982 scopus 로고    scopus 로고
    • Phase i trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
    • Phuphanich S, Wheeler CJ, Rudnick JD et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol. Immunother. 62(1), 125-135 (2013).
    • (2013) Cancer Immunol. Immunother , vol.62 , Issue.1 , pp. 125-135
    • Phuphanich, S.1    Wheeler, C.J.2    Rudnick, J.D.3
  • 109
    • 79951962152 scopus 로고    scopus 로고
    • Phase i trial of a personalized peptide vaccine for patients positive for human leukocyte antigen-A24 with recurrent or progressive glioblastoma multiforme
    • Terasaki M, Shibui S, Narita Y et al. Phase I trial of a personalized peptide vaccine for patients positive for human leukocyte antigen-A24 with recurrent or progressive glioblastoma multiforme. J. Clin. Oncol. 29(3), 337-344 (2011).
    • (2011) J. Clin. Oncol , vol.29 , Issue.3 , pp. 337-344
    • Terasaki, M.1    Shibui, S.2    Narita, Y.3
  • 111
    • 39149136486 scopus 로고    scopus 로고
    • Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma
    • DOI 10.1215/15228517-2007-035
    • Mitchell DA, Xie W, Schmittling R et al. Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma. Neuro-oncology 10(1), 10-18 (2008). (Pubitemid 351250896)
    • (2008) Neuro-Oncology , vol.10 , Issue.1 , pp. 10-18
    • Mitchell, D.A.1    Xie, W.2    Schmittling, R.3    Learn, C.4    Friedman, A.5    McLendon, R.E.6    Sampson, J.H.7
  • 112
    • 47749142471 scopus 로고    scopus 로고
    • Detection of human cytomegalovirus in different histological types of gliomas
    • Scheurer ME, Bondy ML, Aldape KD, Albrecht T, El-Zein R. Detection of human cytomegalovirus in different histological types of gliomas. Acta Neuropathol. 116(1), 79-86 (2008).
    • (2008) Acta Neuropathol , vol.116 , Issue.1 , pp. 79-86
    • Scheurer, M.E.1    Bondy, M.L.2    Aldape, K.D.3    Albrecht, T.4    El-Zein, R.5
  • 114
    • 79960432578 scopus 로고    scopus 로고
    • Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype
    • Dziurzynski K, Wei J, Qiao W et al. Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype. Clin. Cancer Res. 17(14), 4642-4649 (2011).
    • (2011) Clin. Cancer Res , vol.17 , Issue.14 , pp. 4642-4649
    • Dziurzynski, K.1    Wei, J.2    Qiao, W.3
  • 115
    • 80155131275 scopus 로고    scopus 로고
    • Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype
    • Soroceanu L, Matlaf L, Bezrookove V et al. Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype. Cancer Res. 71(21), 6643-6653 (2011).
    • (2011) Cancer Res , vol.71 , Issue.21 , pp. 6643-6653
    • Soroceanu, L.1    Matlaf, L.2    Bezrookove, V.3
  • 116
    • 48249102647 scopus 로고    scopus 로고
    • Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate
    • Prins RM, Cloughesy TF, Liau LM. Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate. N. Engl. J. Med. 359(5), 539-541 (2008).
    • (2008) N. Engl. J. Med , vol.359 , Issue.5 , pp. 539-541
    • Prins, R.M.1    Cloughesy, T.F.2    Liau, L.M.3
  • 117
    • 84856845120 scopus 로고    scopus 로고
    • Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma
    • Ghazi A, Ashoori A, Hanley PJ et al. Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma. J. Immunother. 35(2), 159-168 (2012).
    • (2012) J. Immunother , vol.35 , Issue.2 , pp. 159-168
    • Ghazi, A.1    Ashoori, A.2    Hanley, P.J.3
  • 118
    • 0033485764 scopus 로고    scopus 로고
    • Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression
    • Lee KH, Wang E, Nielsen MB et al. Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. J. Immunol. 163(11), 6292-6300 (1999).
    • (1999) J. Immunol , vol.163 , Issue.11 , pp. 6292-6300
    • Lee, K.H.1    Wang, E.2    Nielsen, M.B.3
  • 119
    • 0033855629 scopus 로고    scopus 로고
    • Failure of cancer vaccines: The significant limitations of this approach to immunotherapy
    • Bodey B, Bodey B Jr, Siegel SE, Kaiser HE. Failure of cancer vaccines: the significant limitations of this approach to immunotherapy. Anticancer Res. 20(4), 2665-2676 (2000). (Pubitemid 30614482)
    • (2000) Anticancer Research , vol.20 , Issue.4 , pp. 2665-2676
    • Bodey, B.1    Bodey Jr., B.2    Siegel, S.E.3    Kaiser, H.E.4
  • 120
    • 84859709790 scopus 로고    scopus 로고
    • New developments in vaccine research-unveiling the secret of vaccine adjuvants
    • de Veer M, Meeusen E. New developments in vaccine research-unveiling the secret of vaccine adjuvants. Discov. Med. 12(64), 195-204 (2011).
    • (2011) Discov. Med , vol.12 , Issue.64 , pp. 195-204
    • De Veer, M.1    Meeusen, E.2
  • 121
    • 79955859969 scopus 로고    scopus 로고
    • Adjuvants for enhancing the immunogenicity of whole tumor cell vaccines
    • Chiang CL, Kandalaft LE, Coukos G. Adjuvants for enhancing the immunogenicity of whole tumor cell vaccines. Int. Rev. Immunol. 30(2-3), 150-182 (2011).
    • (2011) Int. Rev. Immunol , vol.30 , Issue.2-3 , pp. 150-182
    • Chiang, C.L.1    Kandalaft, L.E.2    Coukos, G.3
  • 123
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat. Rev. Cancer 12(4), 265-277 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , Issue.4 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 124
    • 17644370329 scopus 로고    scopus 로고
    • Cell biology of antigen processing in vitro and in vivo
    • DOI 10.1146/annurev.immunol.22.012703.104538
    • Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu. Rev. Immunol. 23, 975-1028 (2005). (Pubitemid 40563191)
    • (2005) Annual Review of Immunology , vol.23 , pp. 975-1028
    • Trombetta, E.S.1    Mellman, I.2
  • 125
    • 69549103141 scopus 로고    scopus 로고
    • Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
    • Darrasse-Jèze G, Deroubaix S, Mouquet H et al. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J. Exp. Med. 206(9), 1853-1862 (2009).
    • (2009) J. Exp. Med , vol.206 , Issue.9 , pp. 1853-1862
    • Darrasse-Jèze, G.1    Deroubaix, S.2    Mouquet, H.3
  • 126
    • 84863000097 scopus 로고    scopus 로고
    • Immunotherapeutic approach with oligodeoxynucleotides containing CpG motifs (CpG-ODN) in malignant glioma
    • Ursu R, Carpentier AF. Immunotherapeutic approach with oligodeoxynucleotides containing CpG motifs (CpG-ODN) in malignant glioma. Adv. Exp. Med. Biol. 746, 95-108 (2012).
    • (2012) Adv. Exp. Med. Biol , vol.746 , pp. 95-108
    • Ursu, R.1    Carpentier, A.F.2
  • 127
    • 29644446061 scopus 로고    scopus 로고
    • The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: Relation to central nervous system antitumor immunity
    • Prins RM, Craft N, Bruhn KW et al. The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity. J. Immunol. 176(1), 157-164 (2006). (Pubitemid 43023259)
    • (2006) Journal of Immunology , vol.176 , Issue.1 , pp. 157-164
    • Prins, R.M.1    Craft, N.2    Bruhn, K.W.3    Khan-Farooqi, H.4    Koya, R.C.5    Stripecke, R.6    Miller, J.F.7    Liau, L.M.8
  • 128
    • 33847674371 scopus 로고    scopus 로고
    • Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models
    • Zhu X, Nishimura F, Sasaki K et al. Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models. J. Transl. Med. 5, 10 (2007).
    • (2007) J. Transl. Med , vol.5 , pp. 10
    • Zhu, X.1    Nishimura, F.2    Sasaki, K.3
  • 130
    • 0034060821 scopus 로고    scopus 로고
    • Keyhole limpet haemocyanin in experimental bladder cancer
    • Linn JF, Black P, Derksen K, Rübben H, Thüroff JW. Keyhole limpet haemocyanin in experimental bladder cancer: literature review and own results. Eur. Urol. 37(Suppl. 3), 34-40 (2000). (Pubitemid 30248577)
    • (2000) European Urology , vol.37 , Issue.SUPPL. 3 , pp. 34-40
    • Linn, J.F.1    Black, P.2    Derksen, K.3    Rubben, H.4    Thuroff, J.W.5
  • 131
    • 84860798836 scopus 로고    scopus 로고
    • The regulation of the development and function of dendritic cell subsets by GM-CSF: More than a hematopoietic growth factor
    • Zhan Y, Xu Y, Lew AM. The regulation of the development and function of dendritic cell subsets by GM-CSF: more than a hematopoietic growth factor. Mol. Immunol. 52(1), 30-37 (2012).
    • (2012) Mol. Immunol , vol.52 , Issue.1 , pp. 30-37
    • Zhan, Y.1    Xu, Y.2    Lew, A.M.3
  • 134
    • 22144497779 scopus 로고    scopus 로고
    • Vaccines in cancer: GVAX®, a GM-CSF gene vaccine
    • DOI 10.1586/14760584.4.3.259
    • Nemunaitis J. Vaccines in cancer: GVAX, a GM-CSF gene vaccine. Expert Rev. Vaccines 4(3), 259-274 (2005). (Pubitemid 40978690)
    • (2005) Expert Review of Vaccines , vol.4 , Issue.3 , pp. 259-274
    • Nemunaitis, J.1
  • 135
    • 77952125524 scopus 로고    scopus 로고
    • Use of GM-CSF as an adjuvant with cancer vaccines: Beneficial or detrimental
    • Clive KS, Tyler JA, Clifton GT et al. Use of GM-CSF as an adjuvant with cancer vaccines: beneficial or detrimental Expert Rev. Vaccines 9(5), 519-525 (2010).
    • (2010) Expert Rev. Vaccines , vol.9 , Issue.5 , pp. 519-525
    • Clive, K.S.1    Tyler, J.A.2    Clifton, G.T.3
  • 136
    • 33847258205 scopus 로고    scopus 로고
    • Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
    • DOI 10.1093/annonc/mdl158
    • Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann. Oncol. 18(2), 226-232 (2007). (Pubitemid 46323086)
    • (2007) Annals of Oncology , vol.18 , Issue.2 , pp. 226-232
    • Parmiani, G.1    Castelli, C.2    Pilla, L.3    Santinami, M.4    Colombo, M.P.5    Rivoltini, L.6
  • 139
    • 33646758868 scopus 로고    scopus 로고
    • Induction of Tumor Immunity Following Allogeneic Stem Cell Transplantation
    • DOI 10.1016/S0065-2776(06)90004-2, PII S0065277606900042
    • Wu CJ, Ritz J. Induction of tumor immunity following allogeneic stem cell transplantation. Adv. Immunol. 90, 133-173 (2006). (Pubitemid 43765800)
    • (2006) Advances in Immunology , vol.90 , pp. 133-173
    • Wu, C.J.1    Ritz, J.2
  • 141
    • 74549126817 scopus 로고    scopus 로고
    • Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model
    • Kim TG, Kim CH, Park JS et al. Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model. Clin. Vaccine Immunol. 17(1), 143-153 (2010).
    • (2010) Clin. Vaccine Immunol , vol.17 , Issue.1 , pp. 143-153
    • Kim, T.G.1    Kim, C.H.2    Park, J.S.3
  • 142
    • 4143103624 scopus 로고    scopus 로고
    • Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination
    • DOI 10.1158/1078-0432.CCR-04-0497
    • Wheeler CJ, Das A, Liu G, Yu JS, Black KL. Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination. Clin. Cancer Res. 10(16), 5316-5326 (2004). (Pubitemid 39100466)
    • (2004) Clinical Cancer Research , vol.10 , Issue.16 , pp. 5316-5326
    • Wheeler, C.J.1    Das, A.2    Liu, G.3    Yu, J.S.4    Black, K.L.5
  • 144
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • Machiels JP, Reilly RT, Emens LA et al. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage- colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res. 61(9), 3689-3697 (2001). (Pubitemid 32694981)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3689-3697
    • Machiels, J.-P.H.1    Todd Reilly, R.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5    Weintraub, D.6    Okoye, F.I.7    Jaffee, E.M.8
  • 146
    • 34047181668 scopus 로고    scopus 로고
    • Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor model
    • Park SD, Kim CH, Kim CK et al. Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor model. Vaccine 25(17), 3485-3491 (2007).
    • (2007) Vaccine , vol.25 , Issue.17 , pp. 3485-3491
    • Park, S.D.1    Kim, C.H.2    Kim, C.K.3
  • 148
    • 68549112974 scopus 로고    scopus 로고
    • Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model
    • Banissi C, Ghiringhelli F, Chen L, Carpentier AF. Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model. Cancer Immunol. Immunother. 58(10), 1627-1634 (2009).
    • (2009) Cancer Immunol. Immunother , vol.58 , Issue.10 , pp. 1627-1634
    • Banissi, C.1    Ghiringhelli, F.2    Chen, L.3    Carpentier, A.F.4
  • 149
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • DOI 10.1007/s00262-007-0336-x
    • Jordan JT, Sun W, Hussain SF, DeAngulo G, Prabhu SS, Heimberger AB. Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol. Immunother. 57(1), 123-131 (2008). (Pubitemid 350043644)
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.1 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    DeAngulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 150
    • 81155154274 scopus 로고    scopus 로고
    • Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control
    • Hong M, Puaux AL, Huang C et al. Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control. Cancer Res. 71(22), 6997-7009 (2011).
    • (2011) Cancer Res , vol.71 , Issue.22 , pp. 6997-7009
    • Hong, M.1    Puaux, A.L.2    Huang, C.3
  • 151
    • 75449088610 scopus 로고    scopus 로고
    • FDA drug approval summary: Bevacizumab (Avastin) as treatment of recurrent glioblastoma multiforme
    • Cohen MH, Shen YL, Keegan P, Pazdur R. FDA drug approval summary: bevacizumab (Avastin) as treatment of recurrent glioblastoma multiforme. Oncologist 14(11), 1131-1138 (2009).
    • (2009) Oncologist , vol.14 , Issue.11 , pp. 1131-1138
    • Cohen, M.H.1    Shen, Y.L.2    Keegan, P.3    Pazdur, R.4
  • 152
    • 84879044903 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab added to standard radiotherapy and temozolomide for newly diagnosed glioblastoma: Final progression-free survival and interim overall survival results in AVAglio
    • Yung AW (Ed.), Oxford University Press, Washington DC, USA
    • Chinot O, Wick W, Mason W et al. Phase III trial of bevacizumab added to standard radiotherapy and temozolomide for newly diagnosed glioblastoma: Final progression-free survival and interim overall survival results in AVAglio. In: Society for Neuro-Oncology. Yung AW (Ed.). Oxford University Press, Washington, DC, USA (2012).
    • (2012) Society for Neuro-Oncology
    • Chinot, O.1    Wick, W.2    Mason, W.3
  • 153
    • 62249144303 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced chemotaxis and IL-10 from T cells
    • Shin JY, Yoon IH, Kim JS, Kim B, Park CG. Vascular endothelial growth factor-induced chemotaxis and IL-10 from T cells. Cell. Immunol. 256(1-2), 72-78 (2009).
    • (2009) Cell. Immunol , vol.256 , Issue.1-2 , pp. 72-78
    • Shin, J.Y.1    Yoon, I.H.2    Kim, J.S.3    Kim, B.4    Park, C.G.5
  • 154
    • 0034984740 scopus 로고    scopus 로고
    • VEGF as a mediator of tumor-associated immunodeficiency
    • DOI 10.1385/IR:23:2-3:263
    • Ohm JE, Carbone DP. VEGF as a mediator of tumor-associated immunodeficiency. Immunol. Res. 23(2-3), 263-272 (2001). (Pubitemid 32575367)
    • (2001) Immunologic Research , vol.23 , Issue.2-3 , pp. 263-272
    • Ohm, J.E.1    Carborne, D.P.2
  • 155
    • 34047131797 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and immunosuppression in cancer: Current knowledge and potential for new therapy
    • DOI 10.1517/14712598.7.4.449
    • Johnson BF, Clay TM, Hobeika AC, Lyerly HK, Morse MA. Vascular endothelial growth factor and immunosuppression in cancer: current knowledge and potential for new therapy. Expert Opin. Biol. Ther. 7(4), 449-460 (2007). (Pubitemid 46524672)
    • (2007) Expert Opinion on Biological Therapy , vol.7 , Issue.4 , pp. 449-460
    • Johnson, B.F.1    Clay, T.M.2    Hobeika, A.C.3    Lyerly, H.K.4    Morse, M.A.5
  • 156
    • 48149105835 scopus 로고    scopus 로고
    • Anti-angiogenesis: Making the tumor vulnerable to the immune system
    • Griffioen AW. Anti-angiogenesis: making the tumor vulnerable to the immune system. Cancer Immunol. Immunother. 57(10), 1553-1558 (2008).
    • (2008) Cancer Immunol. Immunother , vol.57 , Issue.10 , pp. 1553-1558
    • Griffioen, A.W.1
  • 157
    • 67349139311 scopus 로고    scopus 로고
    • Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions
    • Mulligan JK, Day TA, Gillespie MB, Rosenzweig SA, Young MR. Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions. Hum. Immunol. 70(6), 375-382 (2009).
    • (2009) Hum. Immunol , vol.70 , Issue.6 , pp. 375-382
    • Mulligan, J.K.1    Day, T.A.2    Gillespie, M.B.3    Rosenzweig, S.A.4    Young, M.R.5
  • 159
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • Gabrilovich D, Ishida T, Oyama T et al. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 92(11), 4150-4166 (1998). (Pubitemid 28544331)
    • (1998) Blood , vol.92 , Issue.11 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3    Ran, S.4    Kravtsov, V.5    Nadaf, S.6    Carbone, D.P.7
  • 162
    • 77955406159 scopus 로고    scopus 로고
    • Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer
    • Shrimali RK, Yu Z, Theoret MR, Chinnasamy D, Restifo NP, Rosenberg SA. Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer. Cancer Res. 70(15), 6171-6180 (2010).
    • (2010) Cancer Res , vol.70 , Issue.15 , pp. 6171-6180
    • Shrimali, R.K.1    Yu, Z.2    Theoret, M.R.3    Chinnasamy, D.4    Restifo, N.P.5    Rosenberg, S.A.6
  • 166
    • 0042063646 scopus 로고    scopus 로고
    • Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression
    • DOI 10.1023/A:1024929724736
    • Prins RM, Graf MR, Merchant RE, Black KL, Wheeler CJ. Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression. J. Neurooncol. 64(1-2), 45-54 (2003). (Pubitemid 36992459)
    • (2003) Journal of Neuro-Oncology , vol.64 , Issue.1-2 , pp. 45-54
    • Prins, R.M.1    Graf, M.R.2    Merchant, R.E.3    Black, K.L.4    Wheeler, C.J.5
  • 167
    • 0142179258 scopus 로고    scopus 로고
    • + T Cell Production Strongly Influences Tumor Antigen Recognition and Age-Dependent Glioma Mortality
    • Wheeler CJ, Black KL, Liu G et al. Thymic CD8+ T cell production strongly influences tumor antigen recognition and age-dependent glioma mortality. J. Immunol. 171(9), 4927-4933 (2003). (Pubitemid 37310617)
    • (2003) Journal of Immunology , vol.171 , Issue.9 , pp. 4927-4933
    • Wheeler, C.J.1    Black, K.L.2    Liu, G.3    Ying, H.4    Yu, J.S.5    Zhang, W.6    Lee, P.K.7
  • 168
    • 84870982871 scopus 로고    scopus 로고
    • Stratification according to HGG-IMMUNO RPA model predicts outcome in a large group of patients with relapsed malignant glioma treated by adjuvant postoperative dendritic cell vaccination
    • De Vleeschouwer S, Ardon H, Van Calenbergh F et al. Stratification according to HGG-IMMUNO RPA model predicts outcome in a large group of patients with relapsed malignant glioma treated by adjuvant postoperative dendritic cell vaccination. Cancer Immunol. Immunother. 61(11), 2105-2112 (2012).
    • (2012) Cancer Immunol. Immunother , vol.61 , Issue.11 , pp. 2105-2112
    • De Vleeschouwer, S.1    Ardon, H.2    Van Calenbergh, F.3
  • 169
    • 84859258334 scopus 로고    scopus 로고
    • Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients
    • Fong B, Jin R, Wang X et al. Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients. PLoS ONE 7(4), e32614 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.4
    • Fong, B.1    Jin, R.2    Wang, X.3
  • 170
    • 22344450341 scopus 로고    scopus 로고
    • Glioblastoma patients exhibit circulating tumor-specific CD8+ T cells
    • DOI 10.1158/1078-0432.CCR-05-0545
    • Tang J, Flomenberg P, Harshyne L, Kenyon L, Andrews DW. Glioblastoma patients exhibit circulating tumor-specific CD8+ T cells. Clin. Cancer Res. 11(14), 5292-5299 (2005). (Pubitemid 41003718)
    • (2005) Clinical Cancer Research , vol.11 , Issue.14 , pp. 5292-5299
    • Tang, J.1    Flomenberg, P.2    Harshyne, L.3    Kenyon, L.4    Andrews, D.W.5
  • 171
    • 84855604775 scopus 로고    scopus 로고
    • Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment
    • Jackson C, Ruzevick J, Phallen J, Belcaid Z, Lim M. Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment. Clin. Dev. Immunol. 2011, 732413 (2011).
    • (2011) Clin. Dev. Immunol , vol.2011 , pp. 732413
    • Jackson, C.1    Ruzevick, J.2    Phallen, J.3    Belcaid, Z.4    Lim, M.5
  • 172
    • 33847052535 scopus 로고    scopus 로고
    • Mechanisms of malignant glioma immune resistance and sources of immunosuppression
    • Gomez GG, Kruse CA. Mechanisms of malignant glioma immune resistance and sources of immunosuppression. Gene Ther. Mol. Biol. 10(A), 133-146 (2006). (Pubitemid 351976185)
    • (2006) Gene Therapy and Molecular Biology , vol.10 , Issue.1 , pp. 133-146
    • Gomez, G.G.1    Kruse, C.A.2
  • 173
    • 70450213189 scopus 로고    scopus 로고
    • Glioblastoma-derived mechanisms of systemic immunosuppression
    • Waziri A. Glioblastoma-derived mechanisms of systemic immunosuppression. Neurosurg. Clin. N. Am. 21(1), 31-42 (2010).
    • (2010) Neurosurg. Clin. N. Am , vol.21 , Issue.1 , pp. 31-42
    • Waziri, A.1
  • 175
    • 0033398454 scopus 로고    scopus 로고
    • Immune defects observed in patients with primary malignant brain tumors
    • DOI 10.1016/S0165-5728(99)00203-9, PII S0165572899002039
    • Dix AR, Brooks WH, Roszman TL, Morford LA. Immune defects observed in patients with primary malignant brain tumors. J. Neuroimmunol. 100(1-2), 216-232 (1999). (Pubitemid 30038255)
    • (1999) Journal of Neuroimmunology , vol.100 , Issue.1-2 , pp. 216-232
    • Dix, A.R.1    Brooks, W.H.2    Roszman, T.L.3    Morford, L.A.4
  • 176
    • 33645502885 scopus 로고    scopus 로고
    • Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma
    • Fecci PE, Mitchell DA, Whitesides JF et al. Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. Cancer Res. 66(6), 3294-3302 (2006).
    • (2006) Cancer Res , vol.66 , Issue.6 , pp. 3294-3302
    • Fecci, P.E.1    Mitchell, D.A.2    Whitesides, J.F.3
  • 178
    • 33748532939 scopus 로고    scopus 로고
    • The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
    • DOI 10.1215/15228517-2006-008
    • Hussain SF, Yang D, Suki D, Aldape K, Grimm E, Heimberger AB. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro-oncology 8(3), 261-279 (2006). (Pubitemid 46542651)
    • (2006) Neuro-Oncology , vol.8 , Issue.3 , pp. 261-279
    • Hussain, S.F.1    Yang, D.2    Suki, D.3    Aldape, K.4    Grimm, E.5    Heimberger, A.B.6
  • 179
    • 25444471021 scopus 로고    scopus 로고
    • Impaired capacity for upregulation of MHC class II in tumor-associated microglia
    • DOI 10.1002/glia.20201
    • Schartner JM, Hagar AR, Van Handel M, Zhang L, Nadkarni N, Badie B. Impaired capacity for upregulation of MHC class II in tumor-associated microglia. Glia 51(4), 279-285 (2005). (Pubitemid 41532103)
    • (2005) GLIA , vol.51 , Issue.4 , pp. 279-285
    • Schartner, J.M.1    Hagar, A.R.2    Van Handel, M.3    Zhang, L.4    Nadkarni, N.5    Badie, B.6
  • 180
    • 79251620102 scopus 로고    scopus 로고
    • Hypoxia potentiates glioma-mediated immunosuppression
    • Wei J, Wu A, Kong LY et al. Hypoxia potentiates glioma-mediated immunosuppression. PLoS One 6(1), e16195 (2011).
    • (2011) PLoS One , vol.6 , Issue.1
    • Wei, J.1    Wu, A.2    Kong, L.Y.3
  • 181
    • 0026541255 scopus 로고
    • Differential expression of transforming growth factor-1,-2, and-3 by glioblastoma cells, astrocytes, and microglia
    • Constam DB, Philipp J, Malipiero UV, ten Dijke P, Schachner M, Fontana A. Differential expression of transforming growth factor-1,-2, and-3 by glioblastoma cells, astrocytes, and microglia. J. Immunol. 148(5), 1404-1410 (1992).
    • (1992) J. Immunol , vol.148 , Issue.5 , pp. 1404-1410
    • Constam, D.B.1    Philipp, J.2    Malipiero, U.V.3    Ten Dijke, P.4    Schachner, M.5    Fontana, A.6
  • 182
    • 0024399070 scopus 로고
    • Immunosuppression and transforming growth factor-β in glioblastoma. Preferential production of transforming growth factor-β2
    • Bodmer S, Strommer K, Frei K et al. Immunosuppression and transforming growth factor-in glioblastoma. Preferential production of transforming growth factor-2. J. Immunol. 143(10), 3222-3229 (1989). (Pubitemid 20010149)
    • (1989) Journal of Immunology , vol.143 , Issue.10 , pp. 3222-3229
    • Bodmer, S.1    Strommer, K.2    Frei, K.3    Siepl, C.4    De Tribolet, N.5    Heid, I.6    Fontana, A.7
  • 183
    • 0032741283 scopus 로고    scopus 로고
    • Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
    • Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin. Cancer Res. 5(10), 2963-2970 (1999). (Pubitemid 29493976)
    • (1999) Clinical Cancer Research , vol.5 , Issue.10 , pp. 2963-2970
    • Gabrilovich, D.I.1    Ishida, T.2    Nadaf, S.3    Ohm, J.E.4    Carbone, D.P.5
  • 184
    • 0025196599 scopus 로고
    • 2 production by glioblastoma cells and its effect on interleukin-2 activation of oncolytic lymphocytes
    • Sawamura Y, Diserens AC, de Tribolet N. In vitro prostaglandin E2 production by glioblastoma cells and its effect on interleukin-2 activation of oncolytic lymphocytes. J. Neurooncol. 9(2), 125-130 (1990). (Pubitemid 20319390)
    • (1990) Journal of Neuro-Oncology , vol.9 , Issue.2 , pp. 125-130
    • Sawamura, Y.1    Diserens, A.-C.2    De Tribolet, N.3
  • 185
    • 0028888764 scopus 로고
    • Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas
    • Huettner C, Paulus W, Roggendorf W. Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas. Am. J. Pathol. 146(2), 317-322 (1995).
    • (1995) Am. J. Pathol , vol.146 , Issue.2 , pp. 317-322
    • Huettner, C.1    Paulus, W.2    Roggendorf, W.3
  • 186
    • 0028347925 scopus 로고
    • Production of IL-10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma
    • Chen Q, Daniel V, Maher DW, Hersey P. Production of IL-10 by melanoma cells: examination of its role in immunosuppression mediated by melanoma. Int. J. Cancer 56(5), 755-760 (1994). (Pubitemid 24086782)
    • (1994) International Journal of Cancer , vol.56 , Issue.5 , pp. 755-760
    • Chen, Q.1    Daniel, V.2    Maher, D.W.3    Hersey, P.4
  • 187
    • 0028807156 scopus 로고
    • Human glioma-derived interleukin-10 inhibits antitumor immune responses in vitro
    • discussion 1166
    • Hishii M, Nitta T, Ishida H et al. Human glioma-derived interleukin-10 inhibits antitumor immune responses in vitro. Neurosurgery 37(6), 1160-1166; discussion 1166 (1995).
    • (1995) Neurosurgery , vol.37 , Issue.6 , pp. 1160-1166
    • Hishii, M.1    Nitta, T.2    Ishida, H.3
  • 188
    • 77953798698 scopus 로고    scopus 로고
    • Immune infiltration of spontaneous mouse astrocytomas is dominated by immunosuppressive cells from early stages of tumor development
    • Tran Thang NN, Derouazi M, Philippin G et al. Immune infiltration of spontaneous mouse astrocytomas is dominated by immunosuppressive cells from early stages of tumor development. Cancer Res. 70(12), 4829-4839 (2010).
    • (2010) Cancer Res , vol.70 , Issue.12 , pp. 4829-4839
    • Tran Thang, N.N.1    Derouazi, M.2    Philippin, G.3
  • 189
    • 34248529706 scopus 로고    scopus 로고
    • Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1
    • DOI 10.1158/0008-5472.CAN-06-4783
    • Roth P, Mittelbronn M, Wick W, Meyermann R, Tatagiba M, Weller M. Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1. Cancer Res. 67(8), 3540-3544 (2007). (Pubitemid 46762134)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3540-3544
    • Roth, P.1    Mittelbronn, M.2    Wick, W.3    Meyermann, R.4    Tatagiba, M.5    Weller, M.6
  • 190
    • 0034018970 scopus 로고    scopus 로고
    • Human glioma immunobiology in vitro: Implications for immunogene therapy
    • discussion 1177
    • Parney IF, Farr-Jones MA, Chang LJ, Petruk KC. Human glioma immunobiology in vitro: implications for immunogene therapy. Neurosurgery 46(5), 1169-1177; discussion 1177 (2000).
    • (2000) Neurosurgery , vol.46 , Issue.5 , pp. 1169-1177
    • Parney, I.F.1    Farr-Jones, M.A.2    Chang, L.J.3    Petruk, K.C.4
  • 191
    • 0029610610 scopus 로고
    • The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-β, T-cell apoptosis, and the immune privilege of the brain
    • DOI 10.1016/0165-0173(95)00010-0
    • Weller M, Fontana A. The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-, T-cell apoptosis, and the immune privilege of the brain. Brain Res. Brain Res. Rev. 21(2), 128-151 (1995). (Pubitemid 26060933)
    • (1995) Brain Research Reviews , vol.21 , Issue.2 , pp. 128-151
    • Weller, M.1    Fontana, A.2
  • 192
    • 0035879509 scopus 로고    scopus 로고
    • Role of microglia in glioma biology
    • DOI 10.1002/jemt.1125
    • Badie B, Schartner J. Role of microglia in glioma biology. Microsc. Res. Tech. 54(2), 106-113 (2001). (Pubitemid 32645875)
    • (2001) Microscopy Research and Technique , vol.54 , Issue.2 , pp. 106-113
    • Badie, B.1    Schartner, J.2
  • 193
    • 84864709456 scopus 로고    scopus 로고
    • The molecular profile of microglia under the influence of glioma
    • Li W, Graeber MB. The molecular profile of microglia under the influence of glioma. Neuro-oncology 14(8), 958-978 (2012).
    • (2012) Neuro-oncology , vol.14 , Issue.8 , pp. 958-978
    • Li, W.1    Graeber, M.B.2
  • 194
    • 33748481603 scopus 로고    scopus 로고
    • An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
    • DOI 10.1215/15228517-2006-006
    • El Andaloussi A, Lesniak MS. An increase in CD4+CD25+FoxP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme. Neuro-oncology 8(3), 234-243 (2006). (Pubitemid 46542648)
    • (2006) Neuro-Oncology , vol.8 , Issue.3 , pp. 234-243
    • El Andaloussi, A.1    Lesniak, M.S.2
  • 195
    • 84860358785 scopus 로고    scopus 로고
    • Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: Implications for immunotherapy
    • Crane CA, Ahn BJ, Han SJ, Parsa AT. Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: implications for immunotherapy. Neuro-oncology 14(5), 584-595 (2012).
    • (2012) Neuro-oncology , vol.14 , Issue.5 , pp. 584-595
    • Crane, C.A.1    Ahn, B.J.2    Han, S.J.3    Parsa, A.T.4
  • 196
    • 77955658133 scopus 로고    scopus 로고
    • Prognostic significance and mechanism of Treg infiltration in human brain tumors
    • Jacobs JF, Idema AJ, Bol KF et al. Prognostic significance and mechanism of Treg infiltration in human brain tumors. J. Neuroimmunol. 225(1-2), 195-199 (2010).
    • (2010) J. Neuroimmunol , vol.225 , Issue.1-2 , pp. 195-199
    • Jacobs, J.F.1    Idema, A.J.2    Bol, K.F.3
  • 197
    • 33646879823 scopus 로고    scopus 로고
    • T-cell apoptosis in human glioblastoma multiforme: Implications for immunotherapy
    • DOI 10.1016/j.jneuroim.2006.03.006, PII S016557280600083X
    • Walker DG, Chuah T, Rist MJ, Pender MP. T-cell apoptosis in human glioblastoma multiforme: implications for immunotherapy. J. Neuroimmunol. 175(1-2), 59-68 (2006). (Pubitemid 43786226)
    • (2006) Journal of Neuroimmunology , vol.175 , Issue.1-2 , pp. 59-68
    • Walker, D.G.1    Chuah, T.2    Rist, M.J.3    Pender, M.P.4
  • 198
    • 77954741566 scopus 로고    scopus 로고
    • FasL gene knock-down therapy enhances the antiglioma immune response
    • Jansen T, Tyler B, Mankowski JL et al. FasL gene knock-down therapy enhances the antiglioma immune response. Neuro-oncology 12(5), 482-489 (2010).
    • (2010) Neuro-oncology , vol.12 , Issue.5 , pp. 482-489
    • Jansen, T.1    Tyler, B.2    Mankowski, J.L.3
  • 199
    • 84860446616 scopus 로고    scopus 로고
    • Ipilimumab in patients with melanoma and brain metastases: An open-label Phase 2 trial
    • Margolin K, Ernstoff MS, Hamid O et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, Phase 2 trial. Lancet Oncol. 13(5), 459-465 (2012).
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 459-465
    • Margolin, K.1    Ernstoff, M.S.2    Hamid, O.3
  • 200
    • 51149116051 scopus 로고    scopus 로고
    • CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS
    • Hodi FS, Oble DA, Drappatz J et al. CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS. Nat. Clin. Pract. Oncol. 5(9), 557-561 (2008).
    • (2008) Nat. Clin. Pract. Oncol , vol.5 , Issue.9 , pp. 557-561
    • Hodi, F.S.1    Oble, D.A.2    Drappatz, J.3
  • 204
    • 77955665451 scopus 로고    scopus 로고
    • Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions
    • Avril T, Saikali S, Vauleon E et al. Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions. J. Neuroimmunol. 225(1-2), 22-33 (2010).
    • (2010) J. Neuroimmunol , vol.225 , Issue.1-2 , pp. 22-33
    • Avril, T.1    Saikali, S.2    Vauleon, E.3
  • 206
    • 68949085209 scopus 로고    scopus 로고
    • Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors
    • Jacobs JF, Idema AJ, Bol KF et al. Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors. Neuro-oncology 11(4), 394-402 (2009).
    • (2009) Neuro-oncology , vol.11 , Issue.4 , pp. 394-402
    • Jacobs, J.F.1    Idema, A.J.2    Bol, K.F.3
  • 207
    • 73249125835 scopus 로고    scopus 로고
    • B7-H1 is correlated with malignancy-grade gliomas but is not expressed exclusively on tumor stem-like cells
    • Yao Y, Tao R, Wang X, Wang Y, Mao Y, Zhou LF. B7-H1 is correlated with malignancy-grade gliomas but is not expressed exclusively on tumor stem-like cells. Neuro-oncology 11(6), 757-766 (2009).
    • (2009) Neuro-oncology , vol.11 , Issue.6 , pp. 757-766
    • Yao, Y.1    Tao, R.2    Wang, X.3    Wang, Y.4    Mao, Y.5    Zhou, L.F.6
  • 209
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 366(26), 2455-2465 (2012).
    • (2012) N. Engl. J. Med , vol.366 , Issue.26 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 210
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr. Opin. Immunol. 24(2), 207-212 (2012).
    • (2012) Curr. Opin. Immunol , vol.24 , Issue.2 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 211
    • 80052919974 scopus 로고    scopus 로고
    • Monoclonal antibody blockade of IL-2 receptor a during lymphopenia selectively depletes regulatory T cells in mice and humans
    • Mitchell DA, Cui X, Schmittling RJ et al. Monoclonal antibody blockade of IL-2 receptor a during lymphopenia selectively depletes regulatory T cells in mice and humans. Blood 118(11), 3003-3012 (2011).
    • (2011) Blood , vol.118 , Issue.11 , pp. 3003-3012
    • Mitchell, D.A.1    Cui, X.2    Schmittling, R.J.3
  • 212
    • 44349089700 scopus 로고    scopus 로고
    • Treg depletion inhibits efficacy of cancer immunotherapy: Implications for clinical trials
    • Curtin JF, Candolfi M, Fakhouri TM et al. Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials. PLoS ONE 3(4), e1983 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.4
    • Curtin, J.F.1    Candolfi, M.2    Fakhouri, T.M.3
  • 213
    • 33845885624 scopus 로고    scopus 로고
    • Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells
    • Fecci PE, Sweeney AE, Grossi PM et al. Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. Clin. Cancer Res. 12(14 Pt 1), 4294-4305 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.14 PART 1 , pp. 4294-4305
    • Fecci, P.E.1    Sweeney, A.E.2    Grossi, P.M.3
  • 214
    • 79954559096 scopus 로고    scopus 로고
    • T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells
    • Cheng G, Yu A, Malek TR. T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells. Immunol. Rev. 241(1), 63-76 (2011).
    • (2011) Immunol. Rev , vol.241 , Issue.1 , pp. 63-76
    • Cheng, G.1    Yu, A.2    Malek, T.R.3
  • 215
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: Harnessing the T cell response
    • Restifo NP, Dudley ME, Rosenberg SA. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat. Rev. Immunol. 12(4), 269-281 (2012).
    • (2012) Nat. Rev. Immunol , vol.12 , Issue.4 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 216
    • 77957606517 scopus 로고    scopus 로고
    • Successful treatment of melanoma brain metastases with adoptive cell therapy
    • Hong JJ, Rosenberg SA, Dudley ME et al. Successful treatment of melanoma brain metastases with adoptive cell therapy. Clin. Cancer Res. 16(19), 4892-4898 (2010).
    • (2010) Clin. Cancer Res , vol.16 , Issue.19 , pp. 4892-4898
    • Hong, J.J.1    Rosenberg, S.A.2    Dudley, M.E.3
  • 217
  • 220
    • 0041833713 scopus 로고    scopus 로고
    • Effects of local injection of ex vivo expanded autologous tumor-specific T lymphocytes in cases with recurrent malignant gliomas
    • Tsuboi K, Saijo K, Ishikawa E et al. Effects of local injection of ex vivo expanded autologous tumor-specific T lymphocytes in cases with recurrent malignant gliomas. Clin. Cancer Res. 9(9), 3294-3302 (2003). (Pubitemid 37082723)
    • (2003) Clinical Cancer Research , vol.9 , Issue.9 , pp. 3294-3302
    • Tsuboi, K.1    Saijo, K.2    Ishikawa, E.3    Tsurushima, H.4    Takano, S.5    Morishita, Y.6    Ohno, T.7
  • 221
    • 84927577191 scopus 로고    scopus 로고
    • Therapeutic efficacy of adoptive cell transfer on survival of patients with glioblastoma multiforme: Case reports
    • Katakura R, Suzuki Y, Sekine T, Sasaki YF, Fujimiya Y. Therapeutic efficacy of adoptive cell transfer on survival of patients with glioblastoma multiforme: case reports. Case Rep. Oncol. 3(2), 110-124 (2010).
    • (2010) Case Rep. Oncol , vol.3 , Issue.2 , pp. 110-124
    • Katakura, R.1    Suzuki, Y.2    Sekine, T.3    Sasaki, Y.F.4    Fujimiya, Y.5
  • 222
    • 0034292408 scopus 로고    scopus 로고
    • Cross-presentation of tumor antigens to effector T cells is sufficient to mediate effective immunotherapy of established intracranial tumors
    • Plautz GE, Mukai S, Cohen PA, Shu S. Cross-presentation of tumor antigens to effector T cells is sufficient to mediate effective immunotherapy of established intracranial tumors. J. Immunol. 165(7), 3656-3662 (2000). (Pubitemid 32057270)
    • (2000) Journal of Immunology , vol.165 , Issue.7 , pp. 3656-3662
    • Plautz, G.E.1    Mukai, S.2    Cohen, P.A.3    Shu, S.4
  • 223
    • 84863085396 scopus 로고    scopus 로고
    • CAR-T cells and solid tumors: Tuning T cells to challenge an inveterate foe
    • Gilham DE, Debets R, Pule M, Hawkins RE, Abken H. CAR-T cells and solid tumors: tuning T cells to challenge an inveterate foe. Trends Mol. Med. 18(7), 377-384 (2012).
    • (2012) Trends Mol. Med , vol.18 , Issue.7 , pp. 377-384
    • Gilham, D.E.1    Debets, R.2    Pule, M.3    Hawkins, R.E.4    Abken, H.5
  • 225
    • 84862838257 scopus 로고    scopus 로고
    • Chimeric antigen receptors for T cell immunotherapy: Current understanding and future directions
    • Curran KJ, Pegram HJ, Brentjens RJ. Chimeric antigen receptors for T cell immunotherapy: current understanding and future directions. J. Gene Med. 14(6), 405-415 (2012).
    • (2012) J. Gene Med , vol.14 , Issue.6 , pp. 405-415
    • Curran, K.J.1    Pegram, H.J.2    Brentjens, R.J.3
  • 226
    • 69249248185 scopus 로고    scopus 로고
    • Genetically engineered T cells to target EGFRvIII expressing glioblastoma
    • Bullain SS, Sahin A, Szentirmai O et al. Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J. Neurooncol. 94(3), 373-382 (2009).
    • (2009) J. Neurooncol , vol.94 , Issue.3 , pp. 373-382
    • Bullain, S.S.1    Sahin, A.2    Szentirmai, O.3
  • 227
    • 84875198775 scopus 로고    scopus 로고
    • Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma
    • Morgan RA, Johnson LA, Davis JL et al. Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma. Hum. Gene Ther. 23(10), 1043-1053 (2012).
    • (2012) Hum. Gene Ther , vol.23 , Issue.10 , pp. 1043-1053
    • Morgan, R.A.1    Johnson, L.A.2    Davis, J.L.3
  • 228
    • 84859820456 scopus 로고    scopus 로고
    • Stem-like tumor-initiating cells isolated from IL13Ra2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T cells
    • Brown CE, Starr R, Aguilar B et al. Stem-like tumor-initiating cells isolated from IL13Ra2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T cells. Clin. Cancer Res. 18(8), 2199-2209 (2012).
    • (2012) Clin. Cancer Res , vol.18 , Issue.8 , pp. 2199-2209
    • Brown, C.E.1    Starr, R.2    Aguilar, B.3
  • 229
    • 74549196076 scopus 로고    scopus 로고
    • HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors
    • Ahmed N, Salsman VS, Kew Y et al. HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors. Clin. Cancer Res. 16(2), 474-485 (2010).
    • (2010) Clin. Cancer Res , vol.16 , Issue.2 , pp. 474-485
    • Ahmed, N.1    Salsman, V.S.2    Kew, Y.3
  • 230
    • 84867744197 scopus 로고    scopus 로고
    • Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme
    • Crough T, Beagley L, Smith C, Jones L, Walker DG, Khanna R. Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme. Immunol. Cell Biol. 90(9), 872-880 (2012).
    • (2012) Immunol. Cell Biol , vol.90 , Issue.9 , pp. 872-880
    • Crough, T.1    Beagley, L.2    Smith, C.3    Jones, L.4    Walker, D.G.5    Khanna, R.6
  • 231
    • 84861233216 scopus 로고    scopus 로고
    • Sequential immunotherapy by vaccination with GM-CSFexpressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors
    • Agarwalla P, Barnard Z, Fecci P, Dranoff G, Curry WT Jr. Sequential immunotherapy by vaccination with GM-CSFexpressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. J. Immunother. 35(5), 385-389 (2012).
    • (2012) J. Immunother , vol.35 , Issue.5 , pp. 385-389
    • Agarwalla, P.1    Barnard, Z.2    Fecci, P.3    Dranoff, G.4    Curry Jr., W.T.5
  • 232
    • 84860436621 scopus 로고    scopus 로고
    • Combined immunotherapy with granulocyte-macrophage colonystimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: A Phase 1 dose-escalation trial
    • van den Eertwegh AJ, Versluis J, van den Berg HP et al. Combined immunotherapy with granulocyte-macrophage colonystimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a Phase 1 dose-escalation trial. Lancet Oncol. 13(5), 509-517 (2012).
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 509-517
    • Van Den Eertwegh, A.J.1    Versluis, J.2    Van Den Berg, H.P.3
  • 233
    • 84860455345 scopus 로고    scopus 로고
    • Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: A Phase 1 dose-escalation trial
    • Madan RA, Mohebtash M, Arlen PM et al. Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a Phase 1 dose-escalation trial. Lancet Oncol. 13(5), 501-508 (2012).
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 501-508
    • Madan, R.A.1    Mohebtash, M.2    Arlen, P.M.3
  • 234
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immunerelated response criteria
    • Wolchok JD, Hoos A, O'Day S et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immunerelated response criteria. Clin. Cancer Res. 15(23), 7412-7420 (2009).
    • (2009) Clin. Cancer Res , vol.15 , Issue.23 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 235
    • 0037099539 scopus 로고    scopus 로고
    • Phase i trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope
    • author reply 3176-3176; author reply 3177
    • Wolchok JD, Chapman PB. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J. Clin. Oncol. 20(14), 3176; author reply 3176-3176; author reply 3177 (2002).
    • (2002) J. Clin. Oncol , vol.20 , Issue.14 , pp. 3176
    • Wolchok, J.D.1    Chapman, P.B.2
  • 236
    • 79955667525 scopus 로고    scopus 로고
    • Do we need novel radiologic response criteria for brain tumor immunotherapy
    • Okada H, Pollack IF. Do we need novel radiologic response criteria for brain tumor immunotherapy Expert Rev. Neurother. 11(5), 619-622 (2011).
    • (2011) Expert Rev. Neurother , vol.11 , Issue.5 , pp. 619-622
    • Okada, H.1    Pollack, I.F.2
  • 237
    • 42649106522 scopus 로고    scopus 로고
    • Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas
    • DOI 10.1016/S1470-2045(08)70125-6, PII S1470204508701256
    • Brandsma D, Stalpers L, Taal W, Sminia P, van den Bent MJ. Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas. Lancet Oncol. 9(5), 453-461 (2008). (Pubitemid 351597795)
    • (2008) The Lancet Oncology , vol.9 , Issue.5 , pp. 453-461
    • Brandsma, D.1    Stalpers, L.2    Taal, W.3    Sminia, P.4    Van Den Bent, M.J.5
  • 238
    • 77951625266 scopus 로고    scopus 로고
    • Updated response assessment criteria for high-grade gliomas: Response assessment in neuro-oncology working group
    • Wen PY, Macdonald DR, Reardon DA et al. Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group. J. Clin. Oncol. 28(11), 1963-1972 (2010).
    • (2010) J. Clin. Oncol , vol.28 , Issue.11 , pp. 1963-1972
    • Wen, P.Y.1    MacDonald, D.R.2    Reardon, D.A.3


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