Expression of MAGE and GAGE in high-grade brain tumors: A potential target for specific immunotherapy and diagnostic markers

Clinical Cancer Research

Volumn 5, Issue 2, 1999, Pages 335-341

  Scarcella, Deborah L ^a   Chow, C W ^a   Gonzales, Michael F ^b   Economou, Catherine ^a   Brasseur, Francis ^c   Ashley, David M ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR MARKER;

ADULT; AMINO ACID SEQUENCE; ARTICLE; BRAIN TUMOR; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

ADULT; ANTIGENS, NEOPLASM; BRAIN; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; DNA, NEOPLASM; FETUS; HUMANS; IMMUNOTHERAPY; NEOPLASM PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0033049977     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Sampson, J. H., Archer, G. E., Ashley, D. M., Fuchs, H. E., Hale, L. P., Dranoff, G., and Bigner, D. D. Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system. Proc. Natl. Acad. Sci. USA, 93: 10399-10404, 1996.
2. Fakhrai, H., Dorigo, O., Shawler, D. L., Lin, H., Mercola, D., Black, K. L., Royston, I., and Sobol, R. E. Eradication of established intracranial rat gliomas by transforming growth factor β antisense gene therapy. Proc. Natl. Acad. Sci. USA. 93: 2909-2914, 1996.
3. Dillman, R. O., Nayak, S. K., and Beutel, L. Establishing in vitro cultures of autologous tumor cells for use in active specific immunotherapy. J. Immunother., 14: 65-69, 1993.
4. Logan, T. F., Shannon, W., Bryant, J., Kane, P., Wolmark, N., Posner, M., Kirkwood, J. M., Ernstoff, M. S., Futrell, J. W., Straw, L. D., Iwatuski, S., and Bahnson, R. Preparation of viable tumour cell vaccine from human solid tumours: relationship between tumour mass and cell yield. The Tissue Bank, Pittsburgh Cancer Institute. Melanoma Res., 3: 451-455, 1993.
5. Bigner, D. D., Pitts, O. M., and Wikstrand, C. J. Induction of lethal experimental allergic encephalomyelitis in nonhuman primates and guinea pigs with human glioblastoma multiforme tissue. J. Neurosurg., 55: 32-42, 1981.
6. van der Bruggen, P., Traversan, C., Chomez, P., Lurquin, C., De Plaen, E., Van den Eynde, B., Knuth, A., and Boon, T. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science (Washington DC), 254: 1643-1647, 1991.
7. De Plaen, E., Arden, K., Traversari, C., Gaforio, J. J., Szikora, J. P., De Smet, C., Brasseur, F., van der Bruggen, P., Lethé, B., Lurquin, C., Brasseur, R., Chomez, P., De Backer, O., Cavenee, W., and Boon, T. Structure, chromosomal localization, and expression of 12 genes of the MAGE family. Immunogenetics, 40: 360-369, 1994.
8. Boël, P., Wildmann, C., Sensi, M. L., Brasseur, R., Renauld, J. C., Coulie, P., Boon, T., and van der Bruggen, P. BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. Immunity, 2: 167-175, 1995.
9. Van den Eynde, B., Peeters, O., De Backer, O., Gaugler, B., Lucas, S., and Boon, T. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. J. Exp. Med., 182: 689-698, 1995.
10. Lee, K. D., Eura, M., Ogi, K., Nakano, K., Chikamatsu, K., Masuyama, K., and Ishikawa, T. Expression of the MAGE-1, -2, -3, -4, and -6 genes in non-squamous cell carcinoma lesions of the head and neck. Acta Oto-Laryngol., 116: 633-639, 1996.
11. Chi, D. D., Merchant, R. E., Rand, R., Conrad, A. J., Garrison, D., Turner, R., Morton, D. L., and Hoon, D. S. Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas. Am. J. Pathol., 150: 2143-2152, 1997.
12. Kleihues, P., Burger, P. C., and Scheithauer, B. W. Histologic typing of tumours of the central nervous system. In: L. H. Sobin (ed.), WHO International Histological Classification of Tumours, Ed. 2. Berlin: Springer-Verlag, 1993.
13. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
14. Davis, L. G., Dibner, M. D., and Battey, J. F. Guanidine isothiocyanate preparation of RNA. In: Basic Methods in Molecular Biology, pp. 130-135. New York: Elsevier Science Publishing Co., Inc., 1986.
15. Lethé, B., van der Bruggen, P., Brasseur, F., and Boon, T. MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T lymphocyte. Melanoma Res., 7: S83-S88, 1997.
16. Gaugler, B., Van den Eynde, B., van der Bruggen, P., Romero, P., Gaforio, J. J., De Plaen, E., Lethé, B., Brasseur, F., and Boon, T. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med., 179: 921-930, 1994.
17. De Smet, C., Lurquin, C., van der Bruggen, P., De Plaen, E., Brasseur, F., and Boon, T. Sequence and expression pattern of the human MAGE2 gene. Immunogenetics, 39: 121-129, 1994.
18. Cheung, I. Y., and Cheung, N-K. V. Molecular detection of GAGE expression in peripheral blood and bone marrow. Utility as a tumor marker for neuroblastoma. Clin. Cancer Res., 6: 821-828, 1997.
19. De Smet, C., De Backer, O., Faraoni, I., Lurquin, C., Brasseur, F., and Boon, T. The activation of human gene MAGE-1 in tumor cells is correlated with genorne-wide demethylation. Proc. Natl. Acad. Sci. USA, 93: 7149-7153, 1996.
20. Packer, R. J. Re-evaluation of outcome in children with high-grade gliomas treated on a Children's Cancer Group Study, CCG-943: a randomized study of radiation alone versus radiation plus adjuvant CCNU, prednisone, and vincristine chemotherapy. In: Proceedings of the Seventh International Symposium on Pediatric Neuro-oncology. Washington, DC: 1996.
21. Conrad, C. A., Milosavljevic, V. P., and Yung, W. K. A. Advances in chemotherapy for brain tumors. In: P. Y. Wen and P. M. Black (eds.), Neurologic Clinics: Brain Tumors in Adults, Vol. 13, pp. 795-812. Philadelphia: W. B. Saunders Co., 1995.