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Volumn 99, Issue 2, 2010, Pages 261-272

Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: A pilot study

Author keywords

Brain tumors; Dendritic cell vaccination; Glioblastoma multiforme; Immunotherapy

Indexed keywords

CANCER VACCINE; GAMMA INTERFERON; TEMOZOLOMIDE;

EID: 77956061272     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0131-y     Document Type: Article
Times cited : (101)

References (62)
  • 3
    • 0028850852 scopus 로고
    • Randomized phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine, and prednisone with the eight-drugs-in-1-day regimen. Children's Cancer Group
    • 7799011
    • JL Finlay JM Boyett AJ Yates JH Wisoff JM Milstein JR Geyer SJ Bertolone P McGuire JM Cherlow M Tefft, et al. 1995 Randomized phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine, and prednisone with the eight-drugs-in-1-day regimen. Children's Cancer Group J Clin Oncol 13 112 123 7799011
    • (1995) J Clin Oncol , vol.13 , pp. 112-123
    • Finlay, J.L.1    Boyett, J.M.2    Yates, A.J.3    Wisoff, J.H.4    Milstein, J.M.5    Geyer, J.R.6    Bertolone, S.J.7    McGuire, P.8    Cherlow, J.M.9    Tefft, M.10
  • 4
    • 0034515477 scopus 로고    scopus 로고
    • A comparison of treatment results for recurrent malignant gliomas
    • 10.1053/ctrv.2000.0191 11139371
    • C Nieder AL Grosu M Molls 2000 A comparison of treatment results for recurrent malignant gliomas Cancer Treat Rev 26 397 409 10.1053/ctrv.2000.0191 11139371
    • (2000) Cancer Treat Rev , vol.26 , pp. 397-409
    • Nieder, C.1    Grosu, A.L.2    Molls, M.3
  • 5
    • 2142834907 scopus 로고    scopus 로고
    • Pediatric supratentorial high-grade gliomas
    • Tamber MS, Rutka JT (2003) Pediatric supratentorial high-grade gliomas. Neurosurg Focus 14. http://www.medscape.com/viewarticle/449870
    • (2003) Neurosurg Focus , vol.14
    • Tamber, M.S.1    Rutka, J.T.2
  • 6
    • 0029399506 scopus 로고
    • Histopathology, classification, and grading of gliomas
    • 10.1002/glia.440150303 8586458
    • P Kleihues F Soylemezoglu B Schauble BW Scheithauer PC Burger 1995 Histopathology, classification, and grading of gliomas Glia 15 211 221 10.1002/glia.440150303 8586458
    • (1995) Glia , vol.15 , pp. 211-221
    • Kleihues, P.1    Soylemezoglu, F.2    Schauble, B.3    Scheithauer, B.W.4    Burger, P.C.5
  • 7
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • 10.1038/nature05236 17051156
    • S Bao Q Wu RE McLendon Y Hao Q Shi AB Hjelmeland MW Dewhirst DD Bigner JN Rich 2006 Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 444 756 760 10.1038/nature05236 17051156
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 10
    • 0030035947 scopus 로고    scopus 로고
    • Lymphocyte targeting of the central nervous system: A review of afferent and efferent CNS-immune pathways
    • 10.1111/j.1750-3639.1996.tb00855.x 8864284
    • RO Weller B Engelhardt MJ Phillips 1996 Lymphocyte targeting of the central nervous system: a review of afferent and efferent CNS-immune pathways Brain Pathol 6 275 288 10.1111/j.1750-3639.1996.tb00855.x 8864284
    • (1996) Brain Pathol , vol.6 , pp. 275-288
    • Weller, R.O.1    Engelhardt, B.2    Phillips, M.J.3
  • 11
    • 0033855629 scopus 로고    scopus 로고
    • Failure of cancer vaccines: The significant limitations of this approach to immunotherapy
    • 10953341
    • B Bodey B Bodey Jr SE Siegel HE Kaiser 2000 Failure of cancer vaccines: the significant limitations of this approach to immunotherapy Anticancer Res 20 2665 2676 10953341
    • (2000) Anticancer Res , vol.20 , pp. 2665-2676
    • Bodey, B.1    Bodey Jr., B.2    Siegel, S.E.3    Kaiser, H.E.4
  • 12
    • 0032839629 scopus 로고    scopus 로고
    • Prerequisites for the immunotherapy of cancer
    • 10.1007/s002620050568 10431692
    • G Pawelec A Engel M Adibzadeh 1999 Prerequisites for the immunotherapy of cancer Cancer Immunol Immunother 48 214 217 10.1007/s002620050568 10431692
    • (1999) Cancer Immunol Immunother , vol.48 , pp. 214-217
    • Pawelec, G.1    Engel, A.2    Adibzadeh, M.3
  • 13
    • 0025745414 scopus 로고
    • Modulation of T-cell function by gliomas
    • 10.1016/0167-5699(91)90068-5 1958290
    • T Roszman L Elliott W Brooks 1991 Modulation of T-cell function by gliomas Immunol Today 12 370 374 10.1016/0167-5699(91)90068-5 1958290
    • (1991) Immunol Today , vol.12 , pp. 370-374
    • Roszman, T.1    Elliott, L.2    Brooks, W.3
  • 15
    • 0034887334 scopus 로고    scopus 로고
    • The generation of anti-tumoral cells using dendritic cells from the peripheral blood of patients with malignant brain tumors
    • 10.1007/s002620100201 11570586
    • S Yoshida K Morii M Watanabe T Saito K Yamamoto R Tanaka 2001 The generation of anti-tumoral cells using dendritic cells from the peripheral blood of patients with malignant brain tumors Cancer Immunol Immunother 50 321 327 10.1007/s002620100201 11570586
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 321-327
    • Yoshida, S.1    Morii, K.2    Watanabe, M.3    Saito, T.4    Yamamoto, K.5    Tanaka, R.6
  • 16
    • 34547643974 scopus 로고    scopus 로고
    • Persistent IL-10 production is required for glioma growth suppressive activity by Th1-directed effector cells after stimulation with tumor lysate-loaded dendritic cells
    • 10.1007/s11060-007-9362-y 17361330
    • S De Vleeschouwer LI Spencer JL Ceuppens SW Van Gool 2007 Persistent IL-10 production is required for glioma growth suppressive activity by Th1-directed effector cells after stimulation with tumor lysate-loaded dendritic cells J Neurooncol 84 131 140 10.1007/s11060-007-9362-y 17361330
    • (2007) J Neurooncol , vol.84 , pp. 131-140
    • De Vleeschouwer, S.1    Spencer, L.I.2    Ceuppens, J.L.3    Van Gool, S.W.4
  • 17
    • 0031685253 scopus 로고    scopus 로고
    • Bone marrow-derived dendritic cells pulsed with a tumor-specific peptide elicit effective anti-tumor immunity against intracranial neoplasms
    • 10.1002/(SICI)1097-0215(19981005)78:2<196::AID-IJC13>3.0.CO;2-9 9754652
    • H Okada H Tahara MR Shurin J Attanucci KM Giezeman-Smits WK Fellows MT Lotze WH Chambers ME Bozik 1998 Bone marrow-derived dendritic cells pulsed with a tumor-specific peptide elicit effective anti-tumor immunity against intracranial neoplasms Int J Cancer 78 196 201 10.1002/(SICI)1097-0215(19981005) 78:2<196::AID-IJC13>3.0.CO;2-9 9754652
    • (1998) Int J Cancer , vol.78 , pp. 196-201
    • Okada, H.1    Tahara, H.2    Shurin, M.R.3    Attanucci, J.4    Giezeman-Smits, K.M.5    Fellows, W.K.6    Lotze, M.T.7    Chambers, W.H.8    Bozik, M.E.9
  • 18
    • 0029959095 scopus 로고    scopus 로고
    • Cure of established, intracerebral rat gliomas induced by therapeutic immunizations with tumor cells and purified APC or adjuvant IFN-gamma treatment
    • P Siesjo E Visse HO Sjogren 1996 Cure of established, intracerebral rat gliomas induced by therapeutic immunizations with tumor cells and purified APC or adjuvant IFN-gamma treatment J Immunother Emphas Tumor Immunol 19 334 345
    • (1996) J Immunother Emphas Tumor Immunol , vol.19 , pp. 334-345
    • Siesjo, P.1    Visse, E.2    Sjogren, H.O.3
  • 19
    • 69949127667 scopus 로고    scopus 로고
    • DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma
    • 10.1215/15228517-2009-004 19336528
    • W Maes GG Rosas B Verbinnen L Boon S De Vleeschouwer JL Ceuppens SW Van Gool 2009 DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma Neuro Oncol 11 529 542 10.1215/15228517-2009-004 19336528
    • (2009) Neuro Oncol , vol.11 , pp. 529-542
    • Maes, W.1    Rosas, G.G.2    Verbinnen, B.3    Boon, L.4    De Vleeschouwer, S.5    Ceuppens, J.L.6    Van Gool, S.W.7
  • 20
    • 57449084713 scopus 로고    scopus 로고
    • In vivo bioluminescence imaging in an experimental mouse model for dendritic cell based immunotherapy against malignant glioma
    • 10.1007/s11060-008-9691-5 18787761
    • W Maes C Deroose V Reumers O Krylyshkina R Gijsbers V Baekelandt J Ceuppens Z Debyser SW Van Gool 2009 In vivo bioluminescence imaging in an experimental mouse model for dendritic cell based immunotherapy against malignant glioma J Neurooncol 91 127 139 10.1007/s11060-008-9691-5 18787761
    • (2009) J Neurooncol , vol.91 , pp. 127-139
    • Maes, W.1    Deroose, C.2    Reumers, V.3    Krylyshkina, O.4    Gijsbers, R.5    Baekelandt, V.6    Ceuppens, J.7    Debyser, Z.8    Van Gool, S.W.9
  • 24
    • 0036672918 scopus 로고    scopus 로고
    • Maintaining the norm: T-cell homeostasis
    • 12154374
    • SC Jameson 2002 Maintaining the norm: T-cell homeostasis Nat Rev Immunol 2 547 556 12154374
    • (2002) Nat Rev Immunol , vol.2 , pp. 547-556
    • Jameson, S.C.1
  • 25
    • 24944552128 scopus 로고    scopus 로고
    • Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines
    • 10.3171/jns.2005.103.1.0156 16121986
    • J Kjaergaard LX Wang H Kuriyama S Shu GE Plautz 2005 Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines J Neurosurg 103 156 164 10.3171/jns.2005.103.1.0156 16121986
    • (2005) J Neurosurg , vol.103 , pp. 156-164
    • Kjaergaard, J.1    Wang, L.X.2    Kuriyama, H.3    Shu, S.4    Plautz, G.E.5
  • 26
    • 21344462768 scopus 로고    scopus 로고
    • Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy
    • 10.1038/sj.onc.1208519 15897911
    • G Liu Y Akasaki HT Khong CJ Wheeler A Das KL Black JS Yu 2005 Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy Oncogene 24 5226 5234 10.1038/sj.onc.1208519 15897911
    • (2005) Oncogene , vol.24 , pp. 5226-5234
    • Liu, G.1    Akasaki, Y.2    Khong, H.T.3    Wheeler, C.J.4    Das, A.5    Black, K.L.6    Yu, J.S.7
  • 27
    • 0021247642 scopus 로고
    • Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells
    • 10.1007/BF00205425 6231095
    • RJ North 1984 Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells Cancer Immunol Immunother 16 175 181 10.1007/BF00205425 6231095
    • (1984) Cancer Immunol Immunother , vol.16 , pp. 175-181
    • North, R.J.1
  • 28
    • 0022972367 scopus 로고
    • Radiation-induced, immunologically mediated regression of an established tumor as an example of successful therapeutic immunomanipulation. Preferential elimination of suppressor T cells allows sustained production of effector T cells
    • 10.1084/jem.164.5.1652 2945892
    • RJ North 1986 Radiation-induced, immunologically mediated regression of an established tumor as an example of successful therapeutic immunomanipulation. Preferential elimination of suppressor T cells allows sustained production of effector T cells J Exp Med 164 1652 1666 10.1084/jem.164.5.1652 2945892
    • (1986) J Exp Med , vol.164 , pp. 1652-1666
    • North, R.J.1
  • 29
    • 19044398813 scopus 로고    scopus 로고
    • T-cell reconstitution and expansion after hematopoietic stem cell transplantation: 'T' it up!
    • 10.1038/sj.bmt.1704953 15806121
    • DL Porter CH June 2005 T-cell reconstitution and expansion after hematopoietic stem cell transplantation: 'T' it up! Bone Marrow Transplant 35 935 942 10.1038/sj.bmt.1704953 15806121
    • (2005) Bone Marrow Transplant , vol.35 , pp. 935-942
    • Porter, D.L.1    June, C.H.2
  • 30
    • 4143103624 scopus 로고    scopus 로고
    • Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination
    • 10.1158/1078-0432.CCR-04-0497 15328167
    • CJ Wheeler A Das G Liu JS Yu KL Black 2004 Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination Clin Cancer Res 10 5316 5326 10.1158/1078-0432.CCR-04-0497 15328167
    • (2004) Clin Cancer Res , vol.10 , pp. 5316-5326
    • Wheeler, C.J.1    Das, A.2    Liu, G.3    Yu, J.S.4    Black, K.L.5
  • 31
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 10.1016/0003-2697(76)90527-3 942051
    • MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3 942051
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 34
    • 0027417437 scopus 로고
    • The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology
    • 10.1093/jnci/85.5.365 8433390
    • NK Aaronson S Ahmedzai B Bergman M Bullinger A Cull NJ Duez A Filiberti H Flechtner SB Fleishman JC de Haes, et al. 1993 The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology J Natl Cancer Inst 85 365 376 10.1093/jnci/85.5.365 8433390
    • (1993) J Natl Cancer Inst , vol.85 , pp. 365-376
    • Aaronson, N.K.1    Ahmedzai, S.2    Bergman, B.3    Bullinger, M.4    Cull, A.5    Duez, N.J.6    Filiberti, A.7    Flechtner, H.8    Fleishman, S.B.9    De Haes, J.C.10
  • 35
    • 0030918409 scopus 로고    scopus 로고
    • Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement
    • 10.1016/S0895-4356(96)00428-3 9179103
    • M Groenvold MC Klee MA Sprangers NK Aaronson 1997 Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement J Clin Epidemiol 50 441 450 10.1016/S0895-4356(96)00428-3 9179103
    • (1997) J Clin Epidemiol , vol.50 , pp. 441-450
    • Groenvold, M.1    Klee, M.C.2    Sprangers, M.A.3    Aaronson, N.K.4
  • 36
    • 0030226447 scopus 로고    scopus 로고
    • Munster Heidelberg Abilities Scale-A measuring instrument for global comparison of illness sequelae
    • 10.1055/s-2008-1046486 8992097
    • JE Wolff E Daumling A Dirksen A Dabrock M Hartmann H Jurgens 1996 [Munster Heidelberg Abilities Scale-a measuring instrument for global comparison of illness sequelae] Klin Padiatr 208 294 298 10.1055/s-2008-1046486 8992097
    • (1996) Klin Padiatr , vol.208 , pp. 294-298
    • Wolff, J.E.1    Daumling, E.2    Dirksen, A.3    Dabrock, A.4    Hartmann, M.5    Jurgens, H.6
  • 37
    • 0002391815 scopus 로고
    • The clinical evaluation of chemotherapeutic agents in cancer
    • C.M. MacLeod (eds). Columbia University Press New York
    • Karnofsky DA, Burchenal BJ (1949) The clinical evaluation of chemotherapeutic agents in cancer. In: MacLeod CM (ed) Evaluation of chemotherapeutic agents. Columbia University Press, New York, pp 191-205
    • (1949) Evaluation of Chemotherapeutic Agents , pp. 191-205
    • Karnofsky, D.A.1    Burchenal, B.J.2
  • 38
    • 23044479028 scopus 로고    scopus 로고
    • Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment
    • 10.1158/1078-0432.CCR-05-0464 16061868
    • LM Liau RM Prins SM Kiertscher SK Odesa TJ Kremen AJ Giovannone JW Lin DJ Chute PS Mischel TF Cloughesy MD Roth 2005 Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment Clin Cancer Res 11 5515 5525 10.1158/1078-0432.CCR-05-0464 16061868
    • (2005) Clin Cancer Res , vol.11 , pp. 5515-5525
    • Liau, L.M.1    Prins, R.M.2    Kiertscher, S.M.3    Odesa, S.K.4    Kremen, T.J.5    Giovannone, A.J.6    Lin, J.W.7    Chute, D.J.8    Mischel, P.S.9    Cloughesy, T.F.10    Roth, M.D.11
  • 40
    • 0034840181 scopus 로고    scopus 로고
    • Results of a phase i clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells
    • 10.1007/s002620100205 11676393
    • T Kikuchi Y Akasaki M Irie S Homma T Abe T Ohno 2001 Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells Cancer Immunol Immunother 50 337 344 10.1007/s002620100205 11676393
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 337-344
    • Kikuchi, T.1    Akasaki, Y.2    Irie, M.3    Homma, S.4    Abe, T.5    Ohno, T.6
  • 41
    • 7444220033 scopus 로고    scopus 로고
    • Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12
    • 10.1097/00002371-200411000-00005 15534489
    • T Kikuchi Y Akasaki T Abe T Fukuda H Saotome JL Ryan DW Kufe T Ohno 2004 Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12 J Immunother 27 452 459 10.1097/00002371- 200411000-00005 15534489
    • (2004) J Immunother , vol.27 , pp. 452-459
    • Kikuchi, T.1    Akasaki, Y.2    Abe, T.3    Fukuda, T.4    Saotome, H.5    Ryan, J.L.6    Kufe, D.W.7    Ohno, T.8
  • 42
    • 0142089462 scopus 로고    scopus 로고
    • Treatment of a glioblastoma patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides: Case report
    • 10.3171/foc.2000.9.6.9 16817691
    • LM Liau KL Black NA Martin SN Sykes JM Bronstein L Jouben-Steele PS Mischel A Belldegrun TF Cloughesy 2000 Treatment of a glioblastoma patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides: case report Neurosurg Focus 9 e8 10.3171/foc.2000.9.6.9 16817691
    • (2000) Neurosurg Focus , vol.9 , pp. 8
    • Liau, L.M.1    Black, K.L.2    Martin, N.A.3    Sykes, S.N.4    Bronstein, J.M.5    Jouben-Steele, L.6    Mischel, P.S.7    Belldegrun, A.8    Cloughesy, T.F.9
  • 43
    • 0142179258 scopus 로고    scopus 로고
    • Thymic CD8(+) T cell production strongly influences tumor antigen recognition and age-dependent glioma mortality
    • 14568975
    • CJ Wheeler KL Black G Liu H Ying JS Yu W Zhang PK Lee 2003 Thymic CD8(+) T cell production strongly influences tumor antigen recognition and age-dependent glioma mortality J Immunol 171 4927 4933 14568975
    • (2003) J Immunol , vol.171 , pp. 4927-4933
    • Wheeler, C.J.1    Black, K.L.2    Liu, G.3    Ying, H.4    Yu, J.S.5    Zhang, W.6    Lee, P.K.7
  • 44
    • 0242329784 scopus 로고    scopus 로고
    • Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: Results of a clinical phase I/II trial
    • 10.1038/sj.bjc.6601268 14520441
    • R Yamanaka T Abe N Yajima N Tsuchiya J Homma T Kobayashi M Narita M Takahashi R Tanaka 2003 Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: results of a clinical phase I/II trial Br J Cancer 89 1172 1179 10.1038/sj.bjc.6601268 14520441
    • (2003) Br J Cancer , vol.89 , pp. 1172-1179
    • Yamanaka, R.1    Abe, T.2    Yajima, N.3    Tsuchiya, N.4    Homma, J.5    Kobayashi, T.6    Narita, M.7    Takahashi, M.8    Tanaka, R.9
  • 45
  • 47
    • 3142692559 scopus 로고    scopus 로고
    • Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma
    • 10.1158/0008-5472.CAN-03-3505 15256471
    • JS Yu G Liu H Ying WH Yong KL Black CJ Wheeler 2004 Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma Cancer Res 64 4973 4979 10.1158/0008-5472.CAN- 03-3505 15256471
    • (2004) Cancer Res , vol.64 , pp. 4973-4979
    • Yu, J.S.1    Liu, G.2    Ying, H.3    Yong, W.H.4    Black, K.L.5    Wheeler, C.J.6
  • 49
    • 37549021127 scopus 로고    scopus 로고
    • Results of a phase i dendritic cell vaccine trial for malignant astrocytoma: Potential interaction with adjuvant chemotherapy
    • 10.1016/j.jocn.2007.08.007 18083572
    • DG Walker R Laherty FH Tomlinson T Chuah C Schmidt 2008 Results of a phase I dendritic cell vaccine trial for malignant astrocytoma: potential interaction with adjuvant chemotherapy J Clin Neurosci 15 114 121 10.1016/j.jocn.2007.08.007 18083572
    • (2008) J Clin Neurosci , vol.15 , pp. 114-121
    • Walker, D.G.1    Laherty, R.2    Tomlinson, F.H.3    Chuah, T.4    Schmidt, C.5
  • 50
  • 52
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • 10.1007/s00262-007-0336-x 17522861
    • JT Jordan W Sun SF Hussain G DeAngulo SS Prabhu AB Heimberger 2008 Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy Cancer Immunol Immunother 57 123 131 10.1007/s00262-007-0336-x 17522861
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    Deangulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 53
    • 33645502885 scopus 로고    scopus 로고
    • Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma
    • 10.1158/0008-5472.CAN-05-3773 16540683
    • PE Fecci DA Mitchell JF Whitesides W Xie AH Friedman GE Archer JE Herndon DD Bigner G Dranoff JH Sampson 2006 Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma Cancer Res 66 3294 3302 10.1158/0008-5472.CAN-05-3773 16540683
    • (2006) Cancer Res , vol.66 , pp. 3294-3302
    • Fecci, P.E.1    Mitchell, D.A.2    Whitesides, J.F.3    Xie, W.4    Friedman, A.H.5    Archer, G.E.6    Herndon, J.E.7    Bigner, D.D.8    Dranoff, G.9    Sampson, J.H.10
  • 54
    • 0026485541 scopus 로고
    • Monocyte release and plasma levels of interleukin-6 in patients irradiated for cancer
    • 1457747
    • B Petrini B Andersson O Strannegard J Wasserman H Blomgren U Glas 1992 Monocyte release and plasma levels of interleukin-6 in patients irradiated for cancer In Vivo 6 531 534 1457747
    • (1992) In Vivo , vol.6 , pp. 531-534
    • Petrini, B.1    Andersson, B.2    Strannegard, O.3    Wasserman, J.4    Blomgren, H.5    Glas, U.6
  • 55
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • 10.1126/science.1078231 12532024
    • C Pasare R Medzhitov 2003 Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells Science 299 1033 1036 10.1126/science.1078231 12532024
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 56
    • 10844252294 scopus 로고    scopus 로고
    • Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
    • 10.1093/intimm/dxh178 15520045
    • Z Fehervari S Sakaguchi 2004 Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells Int Immunol 16 1769 1780 10.1093/intimm/dxh178 15520045
    • (2004) Int Immunol , vol.16 , pp. 1769-1780
    • Fehervari, Z.1    Sakaguchi, S.2
  • 57
    • 24944433410 scopus 로고    scopus 로고
    • Marrying immunotherapy with chemotherapy: Why say IDO?
    • 10.1158/0008-5472.CAN-05-2213 16166276
    • AJ Muller GC Prendergast 2005 Marrying immunotherapy with chemotherapy: why say IDO? Cancer Res 65 8065 8068 10.1158/0008-5472.CAN-05-2213 16166276
    • (2005) Cancer Res , vol.65 , pp. 8065-8068
    • Muller, A.J.1    Prendergast, G.C.2
  • 58
    • 0042591416 scopus 로고    scopus 로고
    • Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors
    • 12907622
    • AK Nowak BW Robinson RA Lake 2003 Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors Cancer Res 63 4490 4496 12907622
    • (2003) Cancer Res , vol.63 , pp. 4490-4496
    • Nowak, A.K.1    Robinson, B.W.2    Lake, R.A.3
  • 59
    • 33746224205 scopus 로고    scopus 로고
    • Alternating chemo-immunotherapy with temozolomide and low-dose interleukin-2 in patients with metastatic melanoma
    • 10.1097/01.cmr.0000205019.23612.a1 16845332
    • GV Masucci E Mansson-Brahme B Ragnarsson-Olding B Nilsson G Wagenius J Hansson 2006 Alternating chemo-immunotherapy with temozolomide and low-dose interleukin-2 in patients with metastatic melanoma Melanoma Res 16 357 363 10.1097/01.cmr.0000205019.23612.a1 16845332
    • (2006) Melanoma Res , vol.16 , pp. 357-363
    • Masucci, G.V.1    Mansson-Brahme, E.2    Ragnarsson-Olding, B.3    Nilsson, B.4    Wagenius, G.5    Hansson, J.6
  • 60
    • 27944455183 scopus 로고    scopus 로고
    • Dendritic cells are essential for priming but inefficient for boosting antitumour immune response in an orthotopic murine glioma model
    • 10.1007/s00262-005-0040-7 16133115
    • E Jouanneau D Poujol S Gulia I Le Mercier JY Blay MF Belin I Puisieux 2006 Dendritic cells are essential for priming but inefficient for boosting antitumour immune response in an orthotopic murine glioma model Cancer Immunol Immunother 55 254 267 10.1007/s00262-005-0040-7 16133115
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 254-267
    • Jouanneau, E.1    Poujol, D.2    Gulia, S.3    Le Mercier, I.4    Blay, J.Y.5    Belin, M.F.6    Puisieux, I.7
  • 62
    • 33745010017 scopus 로고    scopus 로고
    • Radiotherapy and temozolomide for newly diagnosed glioblastoma: Recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial
    • 10.1200/JCO.2005.04.5963 16735709
    • RO Mirimanoff T Gorlia W Mason MJ van den Bent RD Kortmann B Fisher M Reni AA Brandes J Curschmann S Villa, et al. 2006 Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial J Clin Oncol 24 2563 2569 10.1200/JCO.2005.04.5963 16735709
    • (2006) J Clin Oncol , vol.24 , pp. 2563-2569
    • Mirimanoff, R.O.1    Gorlia, T.2    Mason, W.3    Van Den Bent, M.J.4    Kortmann, R.D.5    Fisher, B.6    Reni, M.7    Brandes, A.A.8    Curschmann, J.9    Villa, S.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.