메뉴 건너뛰기




Volumn 89, Issue 1, 1998, Pages 42-51

Systemic T cell adoptive immunotherapy of malignant gliomas

Author keywords

Adoptive immunotherapy; Clinical trial; Malignant glioma; Staphylococcal enterotoxin A; T lymphocyte

Indexed keywords

CORTICOSTEROID;

EID: 0031832638     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1998.89.1.0042     Document Type: Article
Times cited : (125)

References (51)
  • 1
    • 0027406425 scopus 로고
    • T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors
    • Alexander JP, Kudoh S, Melsop KA, et al: T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors. Cancer Res 53:1380-1387, 1993
    • (1993) Cancer Res , vol.53 , pp. 1380-1387
    • Alexander, J.P.1    Kudoh, S.2    Melsop, K.A.3
  • 2
    • 0029685801 scopus 로고    scopus 로고
    • Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor
    • Arca MJ, Krauss JC, Aruga A, et al: Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor. Cancer Gene Ther 3:39-47, 1996
    • (1996) Cancer Gene Ther , vol.3 , pp. 39-47
    • Arca, M.J.1    Krauss, J.C.2    Aruga, A.3
  • 3
    • 0024510754 scopus 로고
    • Intratumoral LAK cell and interleukin-2 therapy of human gliomas
    • Barba D, Saris SC, Holder C, et al: Intratumoral LAK cell and interleukin-2 therapy of human gliomas. J Neurosurg 70: 175-182, 1989
    • (1989) J Neurosurg , vol.70 , pp. 175-182
    • Barba, D.1    Saris, S.C.2    Holder, C.3
  • 4
    • 0028108663 scopus 로고
    • Loco-regional immunotherapy with recombinant interleukin-2 and adherent lymphokine-activated killer cells (A-LAK) in recurrent glioblastoma patients
    • Boiardi A, Silvani A, Ruffini PA, et al: Loco-regional immunotherapy with recombinant interleukin-2 and adherent lymphokine-activated killer cells (A-LAK) in recurrent glioblastoma patients. Cancer Immunol Immunother 39:193-197, 1994
    • (1994) Cancer Immunol Immunother , vol.39 , pp. 193-197
    • Boiardi, A.1    Silvani, A.2    Ruffini, P.A.3
  • 5
    • 0028917333 scopus 로고
    • Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
    • Brem H, Piantadosi S, Burger PC, et al: Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. Lancet 345:1008-1012, 1995
    • (1995) Lancet , vol.345 , pp. 1008-1012
    • Brem, H.1    Piantadosi, S.2    Burger, P.C.3
  • 7
    • 0015461544 scopus 로고
    • Depressed cell-mediated immunity in patients with primary intracranial tumors. Characterization of a humoral immunosuppressive factor
    • Brooks WH, Netsky MG, Normansell DE, et al: Depressed cell-mediated immunity in patients with primary intracranial tumors. Characterization of a humoral immunosuppressive factor. J Exp Med 136:1631-1647, 1972
    • (1972) J Exp Med , vol.136 , pp. 1631-1647
    • Brooks, W.H.1    Netsky, M.G.2    Normansell, D.E.3
  • 8
    • 0024514296 scopus 로고
    • Prostaglandin and thromboxane synthesis by human intracranial tumors
    • Castelli MG, Chiabrando C, Fanelli R, et al: Prostaglandin and thromboxane synthesis by human intracranial tumors. Cancer Res 49:1505-1508, 1989
    • (1989) Cancer Res , vol.49 , pp. 1505-1508
    • Castelli, M.G.1    Chiabrando, C.2    Fanelli, R.3
  • 9
    • 0028059136 scopus 로고
    • Phase Ib trial of granulocyte-macrophage colony-stimulating factor combined with murine monoclonal antibody R24 in patients with metastatic melanoma
    • Chachoua A, Oratz R, Liebes L, et al: Phase Ib trial of granulocyte-macrophage colony-stimulating factor combined with murine monoclonal antibody R24 in patients with metastatic melanoma. J Immunother 16:132-141, 1994
    • (1994) J Immunother , vol.16 , pp. 132-141
    • Chachoua, A.1    Oratz, R.2    Liebes, L.3
  • 10
    • 0031027417 scopus 로고    scopus 로고
    • Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2
    • Chang AE, Aruga A, Cameron MJ, et al: Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2. J Clin Oncol 15: 796-807, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 796-807
    • Chang, A.E.1    Aruga, A.2    Cameron, M.J.3
  • 11
    • 0027412082 scopus 로고
    • Clinical observations on adoptive immunotherapy with vaccine-primed T-lymphocytes secondarily sensitized to tumor in vitro
    • Chang AE, Yoshizawa H, Sakai K, et al: Clinical observations on adoptive immunotherapy with vaccine-primed T-lymphocytes secondarily sensitized to tumor in vitro. Cancer Res 53:1043-1050, 1993
    • (1993) Cancer Res , vol.53 , pp. 1043-1050
    • Chang, A.E.1    Yoshizawa, H.2    Sakai, K.3
  • 12
    • 0023940253 scopus 로고
    • Generation of therapeutic T lymphocytes from tumor-bearing mice by in vitro sensitization. Culture requirements and characterization of immunologic specificity
    • Chou T, Chang AE, Shu S: Generation of therapeutic T lymphocytes from tumor-bearing mice by in vitro sensitization. Culture requirements and characterization of immunologic specificity. J Immunol 140:2453-2461, 1988
    • (1988) J Immunol , vol.140 , pp. 2453-2461
    • Chou, T.1    Chang, A.E.2    Shu, S.3
  • 13
    • 0029987485 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor: An effective adjuvant for protein and peptide-based vaccines
    • Disis ML, Bernhard H, Shiota FM, et al: Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines. Blood 88:202-210, 1996
    • (1996) Blood , vol.88 , pp. 202-210
    • Disis, M.L.1    Bernhard, H.2    Shiota, F.M.3
  • 14
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A, et al: Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony stimulating factor stimulates potent, specific and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 90:3539-3543, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3
  • 15
    • 0029865486 scopus 로고    scopus 로고
    • Eradication of established intracranial rat gliomas by transforming growth factor β antisense gene therapy
    • Fakhrai H, Dorigo O, Shawler DL, et al: Eradication of established intracranial rat gliomas by transforming growth factor β antisense gene therapy. Proc Natl Acad Sci USA 93: 2909-2914, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2909-2914
    • Fakhrai, H.1    Dorigo, O.2    Shawler, D.L.3
  • 16
    • 0027378767 scopus 로고
    • lck in T-cells infiltrating human renal cell carcinoma
    • lck in T-cells infiltrating human renal cell carcinoma. Cancer Res 53:5613-5616, 1993
    • (1993) Cancer Res , vol.53 , pp. 5613-5616
    • Finke, J.H.1    Zea, A.H.2    Stanley, J.3
  • 17
    • 0029094721 scopus 로고
    • Adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 in patients with metastatic malignant melanoma and renal cell carcinoma: A pilot study
    • Goedegebuure PS, Douville LM, Li H, et al: Adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 in patients with metastatic malignant melanoma and renal cell carcinoma: a pilot study. J Clin Oncol 13: 1939-1949, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 1939-1949
    • Goedegebuure, P.S.1    Douville, L.M.2    Li, H.3
  • 18
    • 0029145309 scopus 로고
    • Improved long term survival after intracavitary interleukin-2 and lymphokine-activated killer cells for adults with recurrent malignant glioma
    • Hayes RL, Koslow M, Hiesiger EM, et al: Improved long term survival after intracavitary interleukin-2 and lymphokine-activated killer cells for adults with recurrent malignant glioma. Cancer 76:840-852, 1995
    • (1995) Cancer , vol.76 , pp. 840-852
    • Hayes, R.L.1    Koslow, M.2    Hiesiger, E.M.3
  • 19
    • 0021813303 scopus 로고
    • Functional capacity of solid tissue implants in the brain: Evidence for immunological privilege
    • Head JR, Griffin WST: Functional capacity of solid tissue implants in the brain: evidence for immunological privilege. Proc R Soc B 224:375-387, 1985
    • (1985) Proc R Soc B , vol.224 , pp. 375-387
    • Head, J.R.1    Griffin, W.S.T.2
  • 20
    • 0028888764 scopus 로고
    • Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas
    • Huettner C, Paulus W, Roggendorf W: Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas. Am J Pathol 146:317-322, 1995
    • (1995) Am J Pathol , vol.146 , pp. 317-322
    • Huettner, C.1    Paulus, W.2    Roggendorf, W.3
  • 21
    • 0026581987 scopus 로고
    • Inhibition of tumor-specific cytotoxic T-lymphocyte responses by transforming growth factor ß1
    • Inge TH, Hoover SK, Susskind BM, et al: Inhibition of tumor-specific cytotoxic T-lymphocyte responses by transforming growth factor ß1. Cancer Res 52:1386-1392, 1992
    • (1992) Cancer Res , vol.52 , pp. 1386-1392
    • Inge, T.H.1    Hoover, S.K.2    Susskind, B.M.3
  • 22
    • 0029840436 scopus 로고    scopus 로고
    • Treatment of intracranial tumors by systemic transfer of superantigen-activated tumor-draining lymph node T cells
    • Inoue M, Plautz GE, Shu S: Treatment of intracranial tumors by systemic transfer of superantigen-activated tumor-draining lymph node T cells. Cancer Res 56:4702-4708, 1996
    • (1996) Cancer Res , vol.56 , pp. 4702-4708
    • Inoue, M.1    Plautz, G.E.2    Shu, S.3
  • 23
    • 0022654010 scopus 로고
    • Interleukin-2 and autologous lymphokine-activated killer cells in the treatment of malignant glioma
    • Jacobs SK, Wilson DJ, Kornblith PL, et al: Interleukin-2 and autologous lymphokine-activated killer cells in the treatment of malignant glioma. J Neurosurg 64:743-749, 1986
    • (1986) J Neurosurg , vol.64 , pp. 743-749
    • Jacobs, S.K.1    Wilson, D.J.2    Kornblith, P.L.3
  • 24
    • 0041485051 scopus 로고    scopus 로고
    • Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo
    • Jager E, Ringhoffer M, Dienes HP, et al: Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo. Int J Cancer 67:54-62, 1996
    • (1996) Int J Cancer , vol.67 , pp. 54-62
    • Jager, E.1    Ringhoffer, M.2    Dienes, H.P.3
  • 25
    • 0028142187 scopus 로고
    • Intracranial administrations of single or multiple source allogeneic cytotoxic T lymphocytes: Chronic therapy for primary brain tumors
    • Kruse CA, Schiltz PM, Bellgrau D, et al: Intracranial administrations of single or multiple source allogeneic cytotoxic T lymphocytes: chronic therapy for primary brain tumors. J Neurooncol 19:161-168, 1994
    • (1994) J Neurooncol , vol.19 , pp. 161-168
    • Kruse, C.A.1    Schiltz, P.M.2    Bellgrau, D.3
  • 26
    • 0029744442 scopus 로고    scopus 로고
    • Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response
    • Kwak LW, Young HA, Pennington RW, et al: Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response. Proc Natl Acad Sci USA 93:10972-10977, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10972-10977
    • Kwak, L.W.1    Young, H.A.2    Pennington, R.W.3
  • 27
    • 0025974603 scopus 로고
    • Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy
    • Lillehei KO, Mitchell DH, Johnson SD, et al: Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy. Neurosurgery 28: 16-22, 1991
    • (1991) Neurosurgery , vol.28 , pp. 16-22
    • Lillehei, K.O.1    Mitchell, D.H.2    Johnson, S.D.3
  • 28
    • 0017342530 scopus 로고
    • Immuno-biology of primary intracranial tumors. Part 1: Studies of the cellular and humoral general immune competence of brain-tumor patients
    • Mahaley MS Jr, Brooks WH, Roszman TL, et al: Immuno-biology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients. J Neurosurg 46:467-476, 1977
    • (1977) J Neurosurg , vol.46 , pp. 467-476
    • Mahaley Jr., M.S.1    Brooks, W.H.2    Roszman, T.L.3
  • 29
    • 0028337396 scopus 로고
    • Characteristics and in vivo homing of long-term T-cell lines and clones derived from tumor-draining lymph nodes
    • Matsumura T, Sussman JJ, Krinock RA, et al: Characteristics and in vivo homing of long-term T-cell lines and clones derived from tumor-draining lymph nodes. Cancer Res 54:2744-2750, 1994
    • (1994) Cancer Res , vol.54 , pp. 2744-2750
    • Matsumura, T.1    Sussman, J.J.2    Krinock, R.A.3
  • 30
    • 0026578810 scopus 로고
    • Effect of the expression of transforming growth factor-β2 in primary human glioblastomas on immunosuppression and loss of immune surveillance
    • Maxwell M, Galanopoulos T, Neville-Golden J, et al: Effect of the expression of transforming growth factor-β2 in primary human glioblastomas on immunosuppression and loss of immune surveillance. J Neurosurg 76:799-804, 1992
    • (1992) J Neurosurg , vol.76 , pp. 799-804
    • Maxwell, M.1    Galanopoulos, T.2    Neville-Golden, J.3
  • 31
    • 78651010946 scopus 로고
    • Immunity to homologous grafted skin. III. The fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye
    • Medawar PW: Immunity to homologous grafted skin. III. The fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br J Exp Pathol 29:58-69, 1948
    • (1948) Br J Exp Pathol , vol.29 , pp. 58-69
    • Medawar, P.W.1
  • 32
    • 0024210594 scopus 로고
    • Intralesional infusion of lymphokine-activated killer (LAK) cells and recombinant interleukin-2 (rIL-2) for the treatment of patients with malignant brain tumor
    • Merchant RE, Merchant LH, Cook SHS, et al: Intralesional infusion of lymphokine-activated killer (LAK) cells and recombinant interleukin-2 (rIL-2) for the treatment of patients with malignant brain tumor. Neurosurgery 23:725-732, 1988
    • (1988) Neurosurgery , vol.23 , pp. 725-732
    • Merchant, R.E.1    Merchant, L.H.2    Cook, S.H.S.3
  • 33
    • 0031586038 scopus 로고    scopus 로고
    • Treatment of subcutaneous tumor with adoptively transferred T cells
    • Peng L, Shu S, Krauss JC: Treatment of subcutaneous tumor with adoptively transferred T cells. Cell Immunol 178:24-32, 1997
    • (1997) Cell Immunol , vol.178 , pp. 24-32
    • Peng, L.1    Shu, S.2    Krauss, J.C.3
  • 34
    • 0030219806 scopus 로고    scopus 로고
    • Defining the synergistic effects of irradiation and T-cell immunotherapy for murine intracranial tumors
    • Plautz GE, Inoue M, Shu S: Defining the synergistic effects of irradiation and T-cell immunotherapy for murine intracranial tumors. Cell Immunol 171:277-284, 1996
    • (1996) Cell Immunol , vol.171 , pp. 277-284
    • Plautz, G.E.1    Inoue, M.2    Shu, S.3
  • 35
    • 0031570722 scopus 로고    scopus 로고
    • Treatment of murine gliomas by adoptive transfer of ex vivo activated tumor-draining lymph node cells
    • Plautz GE, Touhalisky JE, Shu S: Treatment of murine gliomas by adoptive transfer of ex vivo activated tumor-draining lymph node cells. Cell Immunol 178:101-107, 1997
    • (1997) Cell Immunol , vol.178 , pp. 101-107
    • Plautz, G.E.1    Touhalisky, J.E.2    Shu, S.3
  • 36
    • 0024166189 scopus 로고
    • Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report
    • Rosenberg SA, Packard BS, Aebersold PM, et al: Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report. N Engl J Med 319:1675-1680, 1988
    • (1988) N Engl J Med , vol.319 , pp. 1675-1680
    • Rosenberg, S.A.1    Packard, B.S.2    Aebersold, P.M.3
  • 37
    • 0018832524 scopus 로고
    • Immunobiology of primary intracranial tumors. III. Demonstration of a qualitative lymphocyte abnormality in patients with primary brain tumors
    • Roszman TL, Brooks WH: Immunobiology of primary intracranial tumors. III. Demonstration of a qualitative lymphocyte abnormality in patients with primary brain tumors. Clin Exp Immunol 39:395-402, 1980
    • (1980) Clin Exp Immunol , vol.39 , pp. 395-402
    • Roszman, T.L.1    Brooks, W.H.2
  • 38
    • 0024344166 scopus 로고
    • The effect of intravenous interleukin-2 on brain water content
    • Saris SC, Patronas NJ, Rosenberg SA, et al: The effect of intravenous interleukin-2 on brain water content. J Neurosurg 71: 169-174, 1989
    • (1989) J Neurosurg , vol.71 , pp. 169-174
    • Saris, S.C.1    Patronas, N.J.2    Rosenberg, S.A.3
  • 39
    • 0023916583 scopus 로고
    • Penetration of recombinant interleukin-2 across the blood-cerebrospinal fluid barrier
    • Saris SC, Rosenberg SA, Friedman RB: Penetration of recombinant interleukin-2 across the blood-cerebrospinal fluid barrier. J Neurosurg 69:29-34, 1988
    • (1988) J Neurosurg , vol.69 , pp. 29-34
    • Saris, S.C.1    Rosenberg, S.A.2    Friedman, R.B.3
  • 40
    • 0024516737 scopus 로고
    • Antitumor activity and surface phenotypes of human glioma-infiltrating lymphocytes after in vitro expansion in the presence of interleukin 2
    • Sawamura Y, Hosokawa M, Kuppner MC, et al: Antitumor activity and surface phenotypes of human glioma-infiltrating lymphocytes after in vitro expansion in the presence of interleukin 2. Cancer Res 49:1843-1849, 1989
    • (1989) Cancer Res , vol.49 , pp. 1843-1849
    • Sawamura, Y.1    Hosokawa, M.2    Kuppner, M.C.3
  • 41
    • 0023264535 scopus 로고
    • Generation from tumor-bearing mice of lymphocytes with in vitro therapeutic efficacy
    • Shu S, Chou T, Rosenberg SA: Generation from tumor-bearing mice of lymphocytes with in vitro therapeutic efficacy. J Immunol 139:295-304, 1987
    • (1987) J Immunol , vol.139 , pp. 295-304
    • Shu, S.1    Chou, T.2    Rosenberg, S.A.3
  • 42
    • 0028299216 scopus 로고
    • Stimulation of tumor-draining lymph node cells with superantigenic staphylococcal toxins leads to the generation of tumor-specific effector T cells
    • Shu S, Krinock RA, Matsumura T, et al: Stimulation of tumor-draining lymph node cells with superantigenic staphylococcal toxins leads to the generation of tumor-specific effector T cells. J Immunol 152:1277-1288, 1994
    • (1994) J Immunol , vol.152 , pp. 1277-1288
    • Shu, S.1    Krinock, R.A.2    Matsumura, T.3
  • 43
    • 0030944023 scopus 로고    scopus 로고
    • Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer
    • Simons JW, Jaffee EM, Weber CE, et al: Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Res 57:1537-1546, 1997
    • (1997) Cancer Res , vol.57 , pp. 1537-1546
    • Simons, J.W.1    Jaffee, E.M.2    Weber, C.E.3
  • 44
    • 0028478117 scopus 로고
    • Activation of T lymphocytes for the adoptive immunotherapy of cancer
    • Sussman JJ, Shu S, Sondak VK, et al: Activation of T lymphocytes for the adoptive immunotherapy of cancer. Ann Surg Oncol 1:296-306, 1994
    • (1994) Ann Surg Oncol , vol.1 , pp. 296-306
    • Sussman, J.J.1    Shu, S.2    Sondak, V.K.3
  • 45
    • 0029123829 scopus 로고
    • Unique characteristics associated with systemic adoptive immunotherapy of experimental intracerebral tumors
    • Sussman JJ, Wahl WL, Chang AE, et al: Unique characteristics associated with systemic adoptive immunotherapy of experimental intracerebral tumors. J Immunother 18:35-44, 1995
    • (1995) J Immunother , vol.18 , pp. 35-44
    • Sussman, J.J.1    Wahl, W.L.2    Chang, A.E.3
  • 46
    • 0027315755 scopus 로고
    • Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma
    • Tao MH, Levy R: Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma. Nature 362:755-758, 1993
    • (1993) Nature , vol.362 , pp. 755-758
    • Tao, M.H.1    Levy, R.2
  • 47
    • 0028321853 scopus 로고
    • Adoptive immunotherapy of murine intracerebral tumors with anti-CD3/interleukin-2-activated tumor-draining lymph node cells
    • Wahl WL, Sussman JJ, Shu S, et al: Adoptive immunotherapy of murine intracerebral tumors with anti-CD3/interleukin-2-activated tumor-draining lymph node cells. J Immunother 15:242-250, 1994
    • (1994) J Immunother , vol.15 , pp. 242-250
    • Wahl, W.L.1    Sussman, J.J.2    Shu, S.3
  • 48
    • 0018125603 scopus 로고
    • Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas: A cooperative trial
    • Walker MD, Alexander E Jr, Hunt WE: Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas: a cooperative trial. J Neurosurg 49:333-343, 1978
    • (1978) J Neurosurg , vol.49 , pp. 333-343
    • Walker, M.D.1    Alexander Jr., E.2    Hunt, W.E.3
  • 49
    • 0019142613 scopus 로고
    • Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant gliomas after surgery
    • Walker MD, Green SB, Byar DP, et al: Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant gliomas after surgery. N Engl J Med 303:1323-1329, 1980
    • (1980) N Engl J Med , vol.303 , pp. 1323-1329
    • Walker, M.D.1    Green, S.B.2    Byar, D.P.3
  • 50
    • 0023758637 scopus 로고
    • Local administration of autologous lymphokine-activated killer cells and recombinant interleukin 2 to patients with malignant brain tumors
    • Yoshida S, Tanaka R, Takai N, et al: Local administration of autologous lymphokine-activated killer cells and recombinant interleukin 2 to patients with malignant brain tumors. Cancer Res 48:5011-5016, 1988
    • (1988) Cancer Res , vol.48 , pp. 5011-5016
    • Yoshida, S.1    Tanaka, R.2    Takai, N.3
  • 51
    • 0025784078 scopus 로고
    • Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2
    • Yoshizawa H, Chang AE, Shu S: Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2. J Immunol 147: 729-737, 1991
    • (1991) J Immunol , vol.147 , pp. 729-737
    • Yoshizawa, H.1    Chang, A.E.2    Shu, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.