Inhibition of autophagy via p53-mediated disruption of ULK1 in a SCA7 polyglutamine disease model

Journal of Molecular Neuroscience

Volumn 50, Issue 3, 2013, Pages 586-599

  Yu, Xin ^a   Muñoz Alarcón, Andrés ^a   Ajayi, Abiodun ^a   Webling, Kristin E ^a   Steinhof, Anne ^a   Langel, Ülo ^a   Ström, Anna Lena ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Autophagy; FIP200; Neurodegeneration; p53; Polyglutamine; ULK1

Indexed keywords

ATAXIN 7; POLYGLUTAMINE; PROTEIN; PROTEIN P53; ULK1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL FRACTIONATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOLYSIS; GENE DISRUPTION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; NERVE DEGENERATION; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; T LYMPHOCYTE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; WESTERN BLOTTING;

ANIMALS; AUTOPHAGY; BENZOTHIAZOLES; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; NERVE TISSUE PROTEINS; OLIGOPEPTIDES; PC12 CELLS; PEPTIDES; POLYMERIZATION; PROTEIN-SERINE-THREONINE KINASES; RATS; SPINOCEREBELLAR ATAXIAS; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84878934829     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0012-x     Document Type: Article

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