Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model.

BMC neuroscience

Volumn 13, Issue , 2012, Pages

  Ajayi, Abiodun ^a   Yu, Xin ^b   Lindberg, Staffan ^b   Langel, Ulo ^b   Ström, Anna Lena ^b  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 7; ATAXIN-7; COPPER ZINC SUPEROXIDE DISMUTASE; ENZYME INHIBITOR; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; NERVE PROTEIN; OXIDIZING AGENT; PEPTIDE; POLYGLUTAMINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RORA PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

ANIMAL; ARTICLE; CELL LINE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MUTATION; OXIDATIVE STRESS; RAT;

ANIMALS; CELL LINE, TRANSFORMED; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROGEN PEROXIDE; MUTATION; NADPH OXIDASE; NERVE TISSUE PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1; OXIDANTS; OXIDATIVE STRESS; PEPTIDES; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TRANSFECTION;

MLCS; MLOWN;

EID: 84871892028     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-13-86     Document Type: Article

References (0)