-
1
-
-
3943086339
-
Flap endonuclease 1: A central component of DNA metabolism
-
Liu Y, Kao HI, Bambara RA. 2004. Flap endonuclease 1: a central component of DNA metabolism. Annu. Rev. Biochem. 73:589-615
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 589-615
-
-
Liu, Y.1
Kao, H.I.2
Bambara, R.A.3
-
2
-
-
84862776917
-
Intrinsic coupling of lagging-strand synthesis to chromatin assembly
-
Smith DJ, Whitehouse I. Intrinsic coupling of lagging-strand synthesis to chromatin assembly. Nature 483:434-38
-
Nature
, vol.483
, pp. 434-438
-
-
Smith, D.J.1
Whitehouse, I.2
-
3
-
-
0007914702
-
Simian virus 40 DNA replication in vitro
-
Li JJ, Kelly TJ. 1984. Simian virus 40 DNA replication in vitro. Proc. Natl. Acad. Sci. USA 81:6973-77
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 6973-6977
-
-
Li, J.J.1
Kelly, T.J.2
-
4
-
-
33748755119
-
Reconstituted Okazaki fragment processing indicates two pathways of primer removal
-
Rossi ML, Bambara RA. 2006. Reconstituted Okazaki fragment processing indicates two pathways of primer removal. J. Biol. Chem. 281:26051-61
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26051-26061
-
-
Rossi, M.L.1
Bambara, R.A.2
-
5
-
-
0035954737
-
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
-
Bae SH, Bae KH, Kim JA, Seo YS. 2001. RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes. Nature 412:456-61
-
(2001)
Nature
, vol.412
, pp. 456-461
-
-
Bae, S.H.1
Bae, K.H.2
Kim, J.A.3
Seo, Y.S.4
-
6
-
-
0035947571
-
Replication protein A as a "fidelity clamp" for DNA polymerase α
-
Maga G, Frouin I, Spadari S, Hubscher U. 2001. Replication protein A as a "fidelity clamp" for DNA polymerase α. J. Biol. Chem. 276:18235-42
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18235-18242
-
-
Maga, G.1
Frouin, I.2
Spadari, S.3
Hubscher, U.4
-
7
-
-
0030908093
-
Replication protein A: A heterotrimeric, single-strandedDNA-binding protein required for eukaryotic DNA metabolism
-
Wold MS. 1997. Replication protein A: a heterotrimeric, single-strandedDNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66:61-92
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 61-92
-
-
Wold, M.S.1
-
8
-
-
0034724750
-
The pattern of sensitivity of yeast dna2 mutants toDNA damaging agents suggests a role in DSB and postreplication repair pathways
-
Budd ME, Campbell JL. 2000. The pattern of sensitivity of yeast dna2 mutants toDNA damaging agents suggests a role in DSB and postreplication repair pathways. Mutat. Res. 459:173-86
-
(2000)
Mutat. Res.
, vol.459
, pp. 173-186
-
-
Budd, M.E.1
Campbell, J.L.2
-
9
-
-
79955999320
-
Inviability of a DNA2 deletion mutant is due to the DNA damage checkpoint
-
Budd ME, Antoshechkin IA, Reis C, Wold BJ, Campbell JL. 2011. Inviability of a DNA2 deletion mutant is due to the DNA damage checkpoint. Cell Cycle 10:1690-98
-
(2011)
Cell Cycle
, vol.10
, pp. 1690-1698
-
-
Budd, M.E.1
Antoshechkin, I.A.2
Reis, C.3
Wold, B.J.4
Campbell, J.L.5
-
11
-
-
79961110182
-
Its all about flaps: Dna2 and checkpoint activation
-
Burgers PM. 2011. Its all about flaps: Dna2 and checkpoint activation. Cell Cycle 10:2417-18
-
(2011)
Cell Cycle
, vol.10
, pp. 2417-2418
-
-
Burgers, P.M.1
-
12
-
-
79953207705
-
Eukaryotic lagging strand DNA replication employs a multi-pathway mechanism that protects genome integrity
-
Balakrishnan L, Bambara RA. Eukaryotic lagging strand DNA replication employs a multi-pathway mechanism that protects genome integrity. J. Biol. Chem. 286:6865-70
-
J. Biol. Chem.
, vol.286
, pp. 6865-6870
-
-
Balakrishnan, L.1
Bambara, R.A.2
-
13
-
-
78650630757
-
An alternative pathway for Okazaki fragment processing: Resolution of fold-back flaps by Pif1 helicase
-
Pike JE, Henry RA, Burgers PM, Campbell JL, Bambara RA. An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase. J. Biol. Chem. 285:41712-23
-
J. Biol. Chem.
, vol.285
, pp. 41712-41723
-
-
Pike, J.E.1
Henry, R.A.2
Burgers, P.M.3
Campbell, J.L.4
Bambara, R.A.5
-
14
-
-
4043051012
-
Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast
-
Ryu GH, Tanaka H, Kim DH, Kim JH, Bae SH, et al. 2004. Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast. Nucleic Acids Res. 32:4205-16
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 4205-4216
-
-
Ryu, G.H.1
Tanaka, H.2
Kim, D.H.3
Kim, J.H.4
Bae, S.H.5
-
15
-
-
0014302193
-
Exonuclease VI, a new nuclease activity associated with E. coli DNA polymerase
-
Klett RP, Cerami A, Reich E. 1968. Exonuclease VI, a new nuclease activity associated with E. coli DNA polymerase. Proc. Natl. Acad. Sci. USA 60:943-50
-
(1968)
Proc. Natl. Acad. Sci. USA
, vol.60
, pp. 943-950
-
-
Klett, R.P.1
Cerami, A.2
Reich, E.3
-
16
-
-
0027215222
-
Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases
-
Lyamichev V, Brow MA, Dahlberg JE. 1993. Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases. Science 260:778-83
-
(1993)
Science
, vol.260
, pp. 778-783
-
-
Lyamichev, V.1
Brow, M.A.2
Dahlberg, J.E.3
-
18
-
-
0015499986
-
Deoxyribonucleic acid polymerase: Two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5′ leads to 3′ exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments
-
Setlow P, Kornberg A. 1972. Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5′ leads to 3′ exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. J. Biol. Chem. 247:232-40
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 232-240
-
-
Setlow, P.1
Kornberg, A.2
-
19
-
-
0015499898
-
Deoxyribonucleic acid polymerase: Two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3′ leads to 5′ exonuclease functions
-
Setlow P, Brutlag D, Kornberg A. 1972. Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3′ leads to 5′ exonuclease functions. J. Biol. Chem. 247:224-31
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 224-231
-
-
Setlow, P.1
Brutlag, D.2
Kornberg, A.3
-
20
-
-
0021252697
-
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. II. Purification and characterization of a host protein required for the replication ofDNA templates devoid of the terminal protein
-
Guggenheimer RA, Nagata K, Kenny M, Hurwitz J. 1984. Protein-primed replication of plasmids containing the terminus of the adenovirus genome. II. Purification and characterization of a host protein required for the replication ofDNA templates devoid of the terminal protein. J. Biol. Chem. 259:7815-25
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 7815-7825
-
-
Guggenheimer, R.A.1
Nagata, K.2
Kenny, M.3
Hurwitz, J.4
-
21
-
-
0021239964
-
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. I. Characterization of an in vitro DNA replication system dependent on adenoviral DNA sequences
-
Guggenheimer RA, Nagata K, Lindenbaum J, Hurwitz J. 1984. Protein-primed replication of plasmids containing the terminus of the adenovirus genome. I. Characterization of an in vitro DNA replication system dependent on adenoviral DNA sequences. J. Biol. Chem. 259:7807-14
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 7807-7814
-
-
Guggenheimer, R.A.1
Nagata, K.2
Lindenbaum, J.3
Hurwitz, J.4
-
22
-
-
0028281443
-
The characterization of a mammalian DNA structure-specific endonuclease
-
Harrington JJ, Lieber MR. 1994. The characterization of a mammalian DNA structure-specific endonuclease. EMBO J. 13:1235-46
-
(1994)
EMBO J.
, vol.13
, pp. 1235-1246
-
-
Harrington, J.J.1
Lieber, M.R.2
-
23
-
-
0031574076
-
A structure-specific endonuclease from cauliflower (Brassica oleracea var. botrytis) inflorescence
-
Kimura S, Kai M, Kobayashi H, Suzuki A, Morioka H, et al. 1997. A structure-specific endonuclease from cauliflower (Brassica oleracea var. botrytis) inflorescence. Nucleic Acids Res. 25:4970-76
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4970-4976
-
-
Kimura, S.1
Kai, M.2
Kobayashi, H.3
Suzuki, A.4
Morioka, H.5
-
24
-
-
0032545389
-
Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism
-
Bibikova M, Wu B, Chi E, Kim KH, Trautman JK, Carroll D. 1998. Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism. J. Biol. Chem. 273:34222-29
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34222-34229
-
-
Bibikova, M.1
Wu, B.2
Chi, E.3
Kim, K.H.4
Trautman, J.K.5
Carroll, D.6
-
25
-
-
61349102407
-
Ribonuclease H: The enzymes in eukaryotes
-
Cerritelli SM, Crouch RJ. 2009. Ribonuclease H: the enzymes in eukaryotes. FEBS J. 276:1494-505
-
(2009)
FEBS J.
, vol.276
, pp. 1494-1505
-
-
Cerritelli, S.M.1
Crouch, R.J.2
-
27
-
-
0027213005
-
Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA
-
Eder PS, Walder RY, Walder JA. 1993. Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA. Biochimie 75:123-26
-
(1993)
Biochimie
, vol.75
, pp. 123-126
-
-
Eder, P.S.1
Walder, R.Y.2
Walder, J.A.3
-
28
-
-
0032484140
-
Partial functional deficiency of E160D flap endonuclease-1 mutant in vitro and in vivo is due to defective cleavage of DNA substrates
-
Frank G, Qiu J, Somsouk M, Weng Y, Somsouk L, et al. 1998. Partial functional deficiency of E160D flap endonuclease-1 mutant in vitro and in vivo is due to defective cleavage of DNA substrates. J. Biol. Chem. 273:33064-72
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33064-33072
-
-
Frank, G.1
Qiu, J.2
Somsouk, M.3
Weng, Y.4
Somsouk, L.5
-
29
-
-
0033512305
-
Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease
-
Qiu J, Qian Y, Frank P, Wintersberger U, Shen B. 1999. Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol. Cell. Biol. 19:8361-71
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8361-8371
-
-
Qiu, J.1
Qian, Y.2
Frank, P.3
Wintersberger, U.4
Shen, B.5
-
30
-
-
79955993911
-
PCNA directs type 2 RNase H activity on DNA replication and repair substrates
-
Bubeck D, Reijns MA, Graham SC, Astell KR, Jones EY, Jackson AP. PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res. 39:3652-66
-
Nucleic Acids Res.
, vol.39
, pp. 3652-3666
-
-
Bubeck, D.1
Reijns, M.A.2
Graham, S.C.3
Astell, K.R.4
Jones, E.Y.5
Jackson, A.P.6
-
31
-
-
0034617275
-
Coordination between the polymerase and 5′-nuclease components of DNA polymerase i of Escherichia coli
-
Xu Y, Grindley ND, Joyce CM. 2000. Coordination between the polymerase and 5′-nuclease components of DNA polymerase I of Escherichia coli. J. Biol. Chem. 275:20949-55
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20949-20955
-
-
Xu, Y.1
Grindley, N.D.2
Joyce, C.M.3
-
32
-
-
0037177823
-
Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate
-
Kao HI, Henricksen LA, Liu Y, Bambara RA. 2002. Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate. J. Biol. Chem. 277:14379-89
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14379-14389
-
-
Kao, H.I.1
Henricksen, L.A.2
Liu, Y.3
Bambara, R.A.4
-
33
-
-
0033597786
-
A comparison of eubacterial and archaeal structure-specific 5′-exonucleases
-
Kaiser MW, Lyamicheva N, Ma W, Miller C, Neri B, et al. 1999. A comparison of eubacterial and archaeal structure-specific 5′-exonucleases. J. Biol. Chem. 274:21387-94
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21387-21394
-
-
Kaiser, M.W.1
Lyamicheva, N.2
Ma, W.3
Miller, C.4
Neri, B.5
-
34
-
-
0037453277
-
The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities
-
Friedrich-Heineken E, Henneke G, Ferrari E, Hübscher U. 2003. The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities. J. Mol. Biol. 328:73-84
-
(2003)
J. Mol. Biol.
, vol.328
, pp. 73-84
-
-
Friedrich-Heineken, E.1
Henneke, G.2
Ferrari, E.3
Hübscher, U.4
-
35
-
-
0036845404
-
The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair
-
Storici F, Henneke G, Ferrari E, Gordenin DA, Hübscher U, Resnick MA. 2002. The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair. EMBO J. 21:5930-42
-
(2002)
EMBO J.
, vol.21
, pp. 5930-5942
-
-
Storici, F.1
Henneke, G.2
Ferrari, E.3
Gordenin, D.A.4
Hübscher, U.5
Resnick, M.A.6
-
36
-
-
0030002197
-
A helical arch allowing single-stranded DNA to thread through T5 5′-exonuclease
-
Ceska TA, Sayers JR, Stier G, Suck D. 1996. A helical arch allowing single-stranded DNA to thread through T5 5′-exonuclease. Nature 382:90-93
-
(1996)
Nature
, vol.382
, pp. 90-93
-
-
Ceska, T.A.1
Sayers, J.R.2
Stier, G.3
Suck, D.4
-
37
-
-
0742321956
-
Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair
-
Chapados BR, Hosfield DJ, Han S, Qiu J, Yelent B, et al. 2004. Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair. Cell 116:39-50
-
(2004)
Cell
, vol.116
, pp. 39-50
-
-
Chapados, B.R.1
Hosfield, D.J.2
Han, S.3
Qiu, J.4
Yelent, B.5
-
38
-
-
0032877660
-
Effect of flap modifications on human FEN1 cleavage
-
Bornarth CJ, Ranalli TA, Henricksen LA, Wahl AF, Bambara RA. 1999. Effect of flap modifications on human FEN1 cleavage. Biochemistry 38:13347-54
-
(1999)
Biochemistry
, vol.38
, pp. 13347-13354
-
-
Bornarth, C.J.1
Ranalli, T.A.2
Henricksen, L.A.3
Wahl, A.F.4
Bambara, R.A.5
-
39
-
-
0035839588
-
Contacts between the 5′ nuclease of DNA polymerase i and its DNA substrate
-
Xu Y, Potapova O, Leschziner AE, Grindley ND, Joyce CM. 2001. Contacts between the 5′ nuclease of DNA polymerase I and its DNA substrate. J. Biol. Chem. 276:30167-77
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30167-30177
-
-
Xu, Y.1
Potapova, O.2
Leschziner, A.E.3
Grindley, N.D.4
Joyce, C.M.5
-
40
-
-
78049375876
-
Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading
-
Gloor JW, Balakrishnan L, Bambara RA. 2010. Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading. J. Biol. Chem. 285:34922-31
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34922-34931
-
-
Gloor, J.W.1
Balakrishnan, L.2
Bambara, R.A.3
-
41
-
-
79953894934
-
Human flap endonuclease structures DNA double-base flipping and a unified understanding of the FEN1 superfamily
-
Tsutakawa SE, Classen S, Chapados BR, Arvai AS, Finger LD, et al. 2011. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell 145:198-211
-
(2011)
Cell
, vol.145
, pp. 198-211
-
-
Tsutakawa, S.E.1
Classen, S.2
Chapados, B.R.3
Arvai, A.S.4
Finger, L.D.5
-
42
-
-
77950363352
-
Dna2 is a structure-specific nuclease, with affinity for 5′-flap intermediates
-
Stewart JA, Campbell JL, Bambara RA. 2010. Dna2 is a structure-specific nuclease, with affinity for 5′-flap intermediates. Nucleic Acids Res. 38:920-30
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 920-930
-
-
Stewart, J.A.1
Campbell, J.L.2
Bambara, R.A.3
-
43
-
-
78649818496
-
Dna2 exhibits a unique strand end-dependent helicase function
-
Balakrishnan L, Polaczek P, Pokharel S, Campbell JL, Bambara RA. 2010. Dna2 exhibits a unique strand end-dependent helicase function. J. Biol. Chem. 285:38861-68
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 38861-38868
-
-
Balakrishnan, L.1
Polaczek, P.2
Pokharel, S.3
Campbell, J.L.4
Bambara, R.A.5
-
44
-
-
21444436726
-
Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks
-
Zheng L, Zhou M, Chai Q, Parrish J, Xue D, et al. 2005. Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks. EMBO Rep. 6:83-89
-
(2005)
EMBO Rep.
, vol.6
, pp. 83-89
-
-
Zheng, L.1
Zhou, M.2
Chai, Q.3
Parrish, J.4
Xue, D.5
-
45
-
-
79951500316
-
Okazaki fragment maturation: Nucleases take centre stage
-
Zheng L, Shen B. 2011. Okazaki fragment maturation: Nucleases take centre stage. J. Mol. Cell Biol. 3:23-30
-
(2011)
J. Mol. Cell Biol.
, vol.3
, pp. 23-30
-
-
Zheng, L.1
Shen, B.2
-
46
-
-
79951573439
-
Functional regulation of FEN1 nuclease and its link to cancer
-
Zheng L, Jia J, Finger LD, Guo Z, Zer C, Shen B. 2011. Functional regulation of FEN1 nuclease and its link to cancer. Nucleic Acids Res. 39:781-94
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 781-794
-
-
Zheng, L.1
Jia, J.2
Finger, L.D.3
Guo, Z.4
Zer, C.5
Shen, B.6
-
47
-
-
0035887046
-
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
-
Brosh RM Jr, von Kobbe C, Sommers JA, Karmakar P, Opresko PL, et al. 2001. Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity. EMBO J. 20:5791-801
-
(2001)
EMBO J.
, vol.20
, pp. 5791-5801
-
-
Brosh Jr., R.M.1
Von Kobbe, C.2
Sommers, J.A.3
Karmakar, P.4
Opresko, P.L.5
-
49
-
-
70350150395
-
C-terminal flap endonuclease (rad27) mutations: Lethal interactions with a DNA ligase i mutation (cdc9-p) and suppression by proliferating cell nuclear antigen (POL30) in Saccharomyces cerevisiae
-
Karanja KK, Livingston DM. 2009. C-terminal flap endonuclease (rad27) mutations: lethal interactions with a DNA ligase I mutation (cdc9-p) and suppression by proliferating cell nuclear antigen (POL30) in Saccharomyces cerevisiae. Genetics 183:63-78
-
(2009)
Genetics
, vol.183
, pp. 63-78
-
-
Karanja, K.K.1
Livingston, D.M.2
-
50
-
-
37549044311
-
Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease 1 in complex with a nicked DNA product: Use of a DPCS kit for efficient protein-DNA complex crystallization
-
Sakurai S, Kitano K, Morioka H, Hakoshima T. 2008. Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease 1 in complex with a nicked DNA product: use of a DPCS kit for efficient protein-DNA complex crystallization. Acta Crystallogr. Sect. F 64:39-43
-
(2008)
Acta Crystallogr. Sect. F
, vol.64
, pp. 39-43
-
-
Sakurai, S.1
Kitano, K.2
Morioka, H.3
Hakoshima, T.4
-
51
-
-
0019203733
-
Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens
-
Drinkwater NR, Miller EC, Miller JA. 1980. Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens. Biochemistry 19:5087-92
-
(1980)
Biochemistry
, vol.19
, pp. 5087-5092
-
-
Drinkwater, N.R.1
Miller, E.C.2
Miller, J.A.3
-
52
-
-
0033152195
-
Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues
-
Nakamura J, Swenberg JA. 1999. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res. 59:2522-26
-
(1999)
Cancer Res.
, vol.59
, pp. 2522-2526
-
-
Nakamura, J.1
Swenberg, J.A.2
-
53
-
-
33644516603
-
Determination of apurinic/apyrimidinic lesions in DNA with high-performance liquid chromatography and tandem mass spectrometry
-
Roberts KP, Sobrino JA, Payton J, Mason LB, Turesky RJ. 2006. Determination of apurinic/apyrimidinic lesions in DNA with high-performance liquid chromatography and tandem mass spectrometry. Chem. Res. Toxicol. 19:300-9
-
(2006)
Chem. Res. Toxicol.
, vol.19
, pp. 300-309
-
-
Roberts, K.P.1
Sobrino, J.A.2
Payton, J.3
Mason, L.B.4
Turesky, R.J.5
-
54
-
-
33746488809
-
DNA repair: From molecular mechanism to human disease
-
Friedberg EC, Aguilera A, Gellert M, Hanawalt PC, Hays JB, et al. 2006. DNA repair: from molecular mechanism to human disease. DNA Repair 5:986-96
-
(2006)
DNA Repair
, vol.5
, pp. 986-996
-
-
Friedberg, E.C.1
Aguilera, A.2
Gellert, M.3
Hanawalt, P.C.4
Hays, J.B.5
-
55
-
-
0033520969
-
Quality control by DNA repair
-
Lindahl T, Wood RD. 1999. Quality control by DNA repair. Science 286:1897-905
-
(1999)
Science
, vol.286
, pp. 1897-1905
-
-
Lindahl, T.1
Wood, R.D.2
-
56
-
-
0029873178
-
Two pathways for base excision repair in mammalian cells
-
Frosina G, Fortini P, Rossi O, Carrozzino F, Raspaglio G, et al. 1996. Two pathways for base excision repair in mammalian cells. J. Biol. Chem. 271:9573-78
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9573-9578
-
-
Frosina, G.1
Fortini, P.2
Rossi, O.3
Carrozzino, F.4
Raspaglio, G.5
-
57
-
-
0030957997
-
Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement for DNase IV (FEN1)
-
Klungland A, Lindahl T. 1997. Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 16:3341-48
-
(1997)
EMBO J.
, vol.16
, pp. 3341-3348
-
-
Klungland, A.1
Lindahl, T.2
-
58
-
-
0035225869
-
Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions
-
Hazra TK, Hill JW, Izumi T, Mitra S. 2001. Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions. Prog. Nucleic Acid Res. Mol. Biol. 68:193-205
-
(2001)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.68
, pp. 193-205
-
-
Hazra, T.K.1
Hill, J.W.2
Izumi, T.3
Mitra, S.4
-
59
-
-
0015504253
-
Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid
-
Lindahl T, Andersson A. 1972. Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid. Biochemistry 11:3618-23
-
(1972)
Biochemistry
, vol.11
, pp. 3618-3623
-
-
Lindahl, T.1
Andersson, A.2
-
60
-
-
0015504248
-
Rate of depurination of native deoxyribonucleic acid
-
Lindahl T, Nyberg B. 1972. Rate of depurination of native deoxyribonucleic acid. Biochemistry 11:3610-18
-
(1972)
Biochemistry
, vol.11
, pp. 3610-3618
-
-
Lindahl, T.1
Nyberg, B.2
-
61
-
-
0025120572
-
The enzymology of apurinic/apyrimidinic endonucleases
-
Doetsch PW, Cunningham RP. 1990. The enzymology of apurinic/apyrimidinic endonucleases. Mutat. Res. 236:173-201
-
(1990)
Mutat. Res.
, vol.236
, pp. 173-201
-
-
Doetsch, P.W.1
Cunningham, R.P.2
-
62
-
-
0025618757
-
Damage specific mammalian endonucleases
-
Haukanes BI, Doetsch PW, Olsen LC, Huq I, Krokan HE, Helland DE. 1990. Damage specific mammalian endonucleases. Basic Life Sci. 53:191-202
-
(1990)
Basic Life Sci.
, vol.53
, pp. 191-202
-
-
Haukanes, B.I.1
Doetsch, P.W.2
Olsen, L.C.3
Huq, I.4
Krokan, H.E.5
Helland, D.E.6
-
63
-
-
0029028964
-
Excision of deoxyribose phosphate residues byDNApolymerase beta during DNA repair
-
Matsumoto Y, Kim K. 1995. Excision of deoxyribose phosphate residues byDNApolymerase beta during DNA repair. Science 269:699-702
-
(1995)
Science
, vol.269
, pp. 699-702
-
-
Matsumoto, Y.1
Kim, K.2
-
64
-
-
0029892846
-
Evidence for an imino intermediate in the DNA polymerase βdeoxyribose phosphate excision reaction
-
Piersen CE, Prasad R, Wilson SH, Lloyd RS. 1996. Evidence for an imino intermediate in the DNA polymerase βdeoxyribose phosphate excision reaction. J. Biol. Chem. 271:17811-15
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17811-17815
-
-
Piersen, C.E.1
Prasad, R.2
Wilson, S.H.3
Lloyd, R.S.4
-
65
-
-
0035837587
-
The major human abasic endonuclease: Formation, consequences and repair of abasic lesions in DNA
-
Wilson DM 3rd, Barsky D. 2001. The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. Mutat. Res. 485:283-307
-
(2001)
Mutat. Res.
, vol.485
, pp. 283-307
-
-
Wilson Iii, D.M.1
Barsky, D.2
-
66
-
-
0036023265
-
Target-controlled propofol requirements at induction of anaesthesia: Effect of remifentanil and midazolam
-
Conway DH, Hasan SK, Simpson ME. 2002. Target-controlled propofol requirements at induction of anaesthesia: effect of remifentanil and midazolam. Eur. J. Anaesthesiol. 19:580-84
-
(2002)
Eur. J. Anaesthesiol.
, vol.19
, pp. 580-584
-
-
Conway, D.H.1
Hasan, S.K.2
Simpson, M.E.3
-
67
-
-
0030018848
-
Specific interaction of DNA polymerase β and DNA ligase i in a multiprotein base excision repair complex from bovine testis
-
Prasad R, Singhal RK, Srivastava DK, Molina JT, Tomkinson AE, Wilson SH. 1996. Specific interaction of DNA polymerase β and DNA ligase I in a multiprotein base excision repair complex from bovine testis. J. Biol. Chem. 271:16000-7
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16000-16007
-
-
Prasad, R.1
Singhal, R.K.2
Srivastava, D.K.3
Molina, J.T.4
Tomkinson, A.E.5
Wilson, S.H.6
-
68
-
-
0030825134
-
The roles of the eukaryotic DNA polymerases in DNA repair synthesis
-
Budd ME, Campbell JL. 1997. The roles of the eukaryotic DNA polymerases in DNA repair synthesis. Mutat. Res. 384:157-67
-
(1997)
Mutat. Res.
, vol.384
, pp. 157-167
-
-
Budd, M.E.1
Campbell, J.L.2
-
69
-
-
0027146121
-
DNA repair genes and proteins of Saccharomyces cerevisiae
-
Prakash S, Sung P, Prakash L. 1993. DNA repair genes and proteins of Saccharomyces cerevisiae. Annu. Rev. Genet. 27:33-70
-
(1993)
Annu. Rev. Genet.
, vol.27
, pp. 33-70
-
-
Prakash, S.1
Sung, P.2
Prakash, L.3
-
70
-
-
0028224999
-
Release of 5′-terminal deoxyribosephosphate residues from incised abasic sites in DNA by the Escherichia coli RecJ protein
-
Dianov G, Sedgwick B, Daly G, Olsson M, Lovett S, Lindahl T. 1994. Release of 5′-terminal deoxyribosephosphate residues from incised abasic sites in DNA by the Escherichia coli RecJ protein. Nucleic Acids Res. 22:993-98
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 993-998
-
-
Dianov, G.1
Sedgwick, B.2
Daly, G.3
Olsson, M.4
Lovett, S.5
Lindahl, T.6
-
71
-
-
0038102398
-
Long-patch DNA repair synthesis during base excision repair in mammalian cells
-
Sattler U, Frit P, Salles B, Calsou P. 2003. Long-patch DNA repair synthesis during base excision repair in mammalian cells. EMBO Rep. 4:363-67
-
(2003)
EMBO Rep.
, vol.4
, pp. 363-367
-
-
Sattler, U.1
Frit, P.2
Salles, B.3
Calsou, P.4
-
73
-
-
0033865403
-
Minisatellites:mutability and genome architecture
-
Vergnaud G, Denoeud F. 2000. Minisatellites:mutability and genome architecture. Genome Res. 10:899-907
-
(2000)
Genome Res.
, vol.10
, pp. 899-907
-
-
Vergnaud, G.1
Denoeud, F.2
-
74
-
-
0037124348
-
Instability of the human minisatellite CEB1 in rad27 and dna2-1 replication-deficient yeast cells
-
Lopes J, Debrauwère H, Buard J, Nicolas A. 2002. Instability of the human minisatellite CEB1 in rad27 and dna2-1 replication-deficient yeast cells. EMBO J. 21:3201-11
-
(2002)
EMBO J.
, vol.21
, pp. 3201-3211
-
-
Lopes, J.1
Debrauwère, H.2
Buard, J.3
Nicolas, A.4
-
75
-
-
77958109197
-
Mechanisms of trinucleotide repeat instability during human development
-
McMurray CT. 2010. Mechanisms of trinucleotide repeat instability during human development. Nat. Rev. Genet. 11:786-99
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 786-799
-
-
McMurray, C.T.1
-
76
-
-
0026316183
-
Fragile X syndrome: Genetic localisation by linkage mapping of two microsatellite repeats FRAXAC1 and FRAXAC2 which immediately flank the fragile site
-
Richards RI, Holman K, Kozman H, Kremer E, Lynch M, et al. 1991. Fragile X syndrome: genetic localisation by linkage mapping of two microsatellite repeats FRAXAC1 and FRAXAC2 which immediately flank the fragile site. J. Med. Genet. 28:818-23
-
(1991)
J. Med. Genet.
, vol.28
, pp. 818-823
-
-
Richards, R.I.1
Holman, K.2
Kozman, H.3
Kremer, E.4
Lynch, M.5
-
77
-
-
0037543991
-
CTGrepeat instability and size variation timing in DNA repair-deficient mice
-
Savouret C, Brisson E, Essers J, Kanaar R, Pastink A, et al. 2003. CTGrepeat instability and size variation timing in DNA repair-deficient mice. EMBO J. 22:2264-73
-
(2003)
EMBO J.
, vol.22
, pp. 2264-2273
-
-
Savouret, C.1
Brisson, E.2
Essers, J.3
Kanaar, R.4
Pastink, A.5
-
78
-
-
0344586043
-
Mutagenicity, toxicity and repair ofDNAbase damage induced by oxidation
-
Bjelland S, Seeberg E. 2003. Mutagenicity, toxicity and repair ofDNAbase damage induced by oxidation. Mutat. Res. 531:37-80
-
(2003)
Mutat. Res.
, vol.531
, pp. 37-80
-
-
Bjelland, S.1
Seeberg, E.2
-
79
-
-
34249337762
-
OGG1 initiates agedependent CAG trinucleotide expansion in somatic cells
-
Kovtun IV, Liu Y, Bjoras M, Klungland A, Wilson SH, McMurray CT. 2007. OGG1 initiates agedependent CAG trinucleotide expansion in somatic cells. Nature 447:447-52
-
(2007)
Nature
, vol.447
, pp. 447-452
-
-
Kovtun, I.V.1
Liu, Y.2
Bjoras, M.3
Klungland, A.4
Wilson, S.H.5
McMurray, C.T.6
-
80
-
-
0033369989
-
Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats
-
Spiro C, Pelletier R, Rolfsmeier ML, Dixon MJ, Lahue RS, et al. 1999. Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats. Mol. Cell 4:1079-85
-
(1999)
Mol. Cell
, vol.4
, pp. 1079-1085
-
-
Spiro, C.1
Pelletier, R.2
Rolfsmeier, M.L.3
Dixon, M.J.4
Lahue, R.S.5
-
81
-
-
70350503915
-
Coordination between polymerase βand FEN1 can modulate CAG repeat expansion
-
Liu Y, Prasad R, Beard WA, Hou EW, Horton JK, et al. 2009. Coordination between polymerase βand FEN1 can modulate CAG repeat expansion. J. Biol. Chem. 284:28352-66
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28352-28366
-
-
Liu, Y.1
Prasad, R.2
Beard, W.A.3
Hou, E.W.4
Horton, J.K.5
-
83
-
-
77956551200
-
Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats
-
Vallur AC, Maizels N. 2010. Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats. J. Biol. Chem. 285:28514-19
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 28514-28519
-
-
Vallur, A.C.1
Maizels, N.2
-
84
-
-
0042307369
-
Huntington disease expansion mutations in humans can occur before meiosis is completed
-
Yoon SR, Dubeau L, de Young M, Wexler NS, Arnheim N. 2003. Huntington disease expansion mutations in humans can occur before meiosis is completed. Proc. Natl. Acad. Sci. USA 100:8834-38
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8834-8838
-
-
Yoon, S.R.1
Dubeau, L.2
De Young, M.3
Wexler, N.S.4
Arnheim, N.5
-
85
-
-
0035872937
-
Replication slippage involves DNA polymerase pausing and dissociation
-
Viguera E, Canceill D, Ehrlich SD. 2001. Replication slippage involves DNA polymerase pausing and dissociation. EMBO J. 20:2587-95
-
(2001)
EMBO J.
, vol.20
, pp. 2587-2595
-
-
Viguera, E.1
Canceill, D.2
Ehrlich, S.D.3
-
86
-
-
45149124860
-
Single-stranded DNA-binding protein in vitro eliminates the orientation-dependent impediment to polymerase passage on CAG/CTG repeats
-
Delagoutte E, Goellner GM, Guo J, Baldacci G, McMurray CT. 2008. Single-stranded DNA-binding protein in vitro eliminates the orientation- dependent impediment to polymerase passage on CAG/CTG repeats. J. Biol. Chem. 283:13341-56
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13341-13356
-
-
Delagoutte, E.1
Goellner, G.M.2
Guo, J.3
Baldacci, G.4
McMurray, C.T.5
-
87
-
-
75749150810
-
Direct restart of a replication fork stalled by a head-on RNA polymerase
-
Pomerantz RT, ODonnell M. 2010. Direct restart of a replication fork stalled by a head-on RNA polymerase. Science 327:590-92
-
(2010)
Science
, vol.327
, pp. 590-592
-
-
Pomerantz, R.T.1
Odonnell, M.2
-
89
-
-
0035099276
-
The "flap" endonuclease gene FEN1 is excluded as a candidate gene implicated in the CAG repeat expansion underlyingHuntington disease
-
Otto CJ, Almqvist E, Hayden MR, Andrew SE. 2001. The "flap" endonuclease gene FEN1 is excluded as a candidate gene implicated in the CAG repeat expansion underlyingHuntington disease. Clin. Genet. 59:122-27
-
(2001)
Clin. Genet.
, vol.59
, pp. 122-127
-
-
Otto, C.J.1
Almqvist, E.2
Hayden, M.R.3
Andrew, S.E.4
-
90
-
-
1942422156
-
Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability
-
Liu Y, Zhang H, Veeraraghavan J, Bambara RA, Freudenreich CH. 2004. Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability. Mol. Cell. Biol. 24:4049-64
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4049-4064
-
-
Liu, Y.1
Zhang, H.2
Veeraraghavan, J.3
Bambara, R.A.4
Freudenreich, C.H.5
-
91
-
-
33947528624
-
Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments
-
Singh P, Zheng L, Chavez V, Qiu J, Shen B. 2007. Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments. J. Biol. Chem. 282:3465-77
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 3465-3477
-
-
Singh, P.1
Zheng, L.2
Chavez, V.3
Qiu, J.4
Shen, B.5
-
92
-
-
84862792679
-
DNA base excision repair: A mechanism of trinucleotide repeat expansion
-
Liu Y, Wilson SH. 2012. DNA base excision repair: a mechanism of trinucleotide repeat expansion. Trends Biochem. Sci. 37:162-72
-
(2012)
Trends Biochem. Sci.
, vol.37
, pp. 162-172
-
-
Liu, Y.1
Wilson, S.H.2
-
93
-
-
0032708840
-
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
-
Manley K, Shirley TL, Flaherty L, Messer A. 1999. Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice. Nat. Genet. 23:471-73
-
(1999)
Nat. Genet.
, vol.23
, pp. 471-473
-
-
Manley, K.1
Shirley, T.L.2
Flaherty, L.3
Messer, A.4
-
94
-
-
25844468819
-
(CAG) n-hairpin DNA binds to Msh2- Msh3 and changes properties of mismatch recognition
-
Owen BA, Yang Z, Lai M, Gajec M, Badger JD 2nd, et al. 2005. (CAG)n-hairpin DNA binds to Msh2- Msh3 and changes properties of mismatch recognition. Nat. Struct. Mol. Biol. 12:663-70
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 663-670
-
-
Owen, B.A.1
Yang, Z.2
Lai, M.3
Gajec, M.4
Badger, I.I.J.D.5
-
95
-
-
84865803054
-
Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions
-
Kantartzis A, Williams GM, Balakrishnan L, Roberts RL, Surtees JA, Bambara RA. 2012. Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions. Cell Rep. 2:216-22
-
(2012)
Cell Rep.
, vol.2
, pp. 216-222
-
-
Kantartzis, A.1
Williams, G.M.2
Balakrishnan, L.3
Roberts, R.L.4
Surtees, J.A.5
Bambara, R.A.6
-
96
-
-
0034616199
-
Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1
-
Tom S, Henricksen LA, Bambara RA. 2000. Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1. J. Biol. Chem. 275:10498-505
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10498-10505
-
-
Tom, S.1
Henricksen, L.A.2
Bambara, R.A.3
-
97
-
-
0029092897
-
Lagging strandDNAsynthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen
-
Li X, Li J, Harrington J, Lieber MR, Burgers PM. 1995. Lagging strandDNAsynthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen. J. Biol. Chem. 270:22109-12
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22109-22112
-
-
Li, X.1
Li, J.2
Harrington, J.3
Lieber, M.R.4
Burgers, P.M.5
-
98
-
-
0029885134
-
Processing of branched DNAintermediates by a complex of human FEN-1 and PCNA
-
Wu X, Li J, Li X, Hsieh CL, Burgers PM, Lieber MR. 1996. Processing of branched DNAintermediates by a complex of human FEN-1 and PCNA. Nucleic Acids Res. 24:2036-43
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 2036-2043
-
-
Wu, X.1
Li, J.2
Li, X.3
Hsieh, C.L.4
Burgers, P.M.5
Lieber, M.R.6
-
99
-
-
0029098312
-
A yeast gene required for DNA replication encodes a protein with homology to DNA helicases
-
Budd ME, Campbell JL. 1995. A yeast gene required for DNA replication encodes a protein with homology to DNA helicases. Proc. Natl. Acad. Sci. USA 92:7642-46
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7642-7646
-
-
Budd, M.E.1
Campbell, J.L.2
-
100
-
-
0031000629
-
A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function
-
Budd ME, Campbell JL. 1997. A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function. Mol. Cell. Biol. 17:2136-42
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2136-2142
-
-
Budd, M.E.1
Campbell, J.L.2
-
101
-
-
0038154016
-
The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants
-
Imamura O, Campbell JL. 2003. The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants. Proc. Natl. Acad. Sci. USA 100:8193-98
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8193-8198
-
-
Imamura, O.1
Campbell, J.L.2
-
102
-
-
52149114891
-
Flap endonuclease-1 and its role in the processes of DNA metabolism in eucaryotic cells
-
Nazarkina Zh K, Lavrik OI, Khodyreva SN. 2008. Flap endonuclease-1 and its role in the processes of DNA metabolism in eucaryotic cells. Mol. Biol. (Mosk) 42:405-21
-
(2008)
Mol. Biol. (Mosk)
, vol.42
, pp. 405-421
-
-
Nazarkina Zh, K.1
Lavrik, O.I.2
Khodyreva, S.N.3
-
103
-
-
0042804874
-
Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation
-
Henneke G, Koundrioukoff S, Hübscher U. 2003. Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation. Oncogene 22:4301-13
-
(2003)
Oncogene
, vol.22
, pp. 4301-4313
-
-
Henneke, G.1
Koundrioukoff, S.2
Hübscher, U.3
-
104
-
-
84864950070
-
Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression
-
Guo Z, Kanjanapangka J, Liu N, Liu S, Liu C, et al. 2012. Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression. Mol. Cell 47:444-56
-
(2012)
Mol. Cell
, vol.47
, pp. 444-456
-
-
Guo, Z.1
Kanjanapangka, J.2
Liu, N.3
Liu, S.4
Liu, C.5
-
105
-
-
0034969453
-
Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300
-
Hasan S, Stucki M, Hassa PO, Imhof R, Gehrig P, et al. 2001. Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300. Mol. Cell 7:1221-31
-
(2001)
Mol. Cell
, vol.7
, pp. 1221-1231
-
-
Hasan, S.1
Stucki, M.2
Hassa, P.O.3
Imhof, R.4
Gehrig, P.5
-
106
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, et al. 2009. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325:834-40
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
-
107
-
-
0037162498
-
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression
-
Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, et al. 2002. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. Proc. Natl. Acad. Sci. USA 99:9924-29
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9924-9929
-
-
Kucherlapati, M.1
Yang, K.2
Kuraguchi, M.3
Zhao, J.4
Lia, M.5
-
108
-
-
77951191213
-
Acetylation ofDna2 endonuclease/ helicase and flap endonuclease 1 by p300 promotesDNAstability by creating long flap intermediates
-
Balakrishnan L, Stewart J, Polaczek P, Campbell JL, Bambara RA. 2010. Acetylation ofDna2 endonuclease/ helicase and flap endonuclease 1 by p300 promotesDNAstability by creating long flap intermediates. J. Biol. Chem. 285:4398-404
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4398-4404
-
-
Balakrishnan, L.1
Stewart, J.2
Polaczek, P.3
Campbell, J.L.4
Bambara, R.A.5
-
109
-
-
46149122987
-
Nucleolar localization and dynamic roles of flap endonuclease 1 in ribosomal DNA replication and damage repair
-
Guo Z, Qian L, Liu R, Dai H, Zhou M, et al. 2008. Nucleolar localization and dynamic roles of flap endonuclease 1 in ribosomal DNA replication and damage repair. Mol. Cell. Biol. 28:4310-19
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4310-4319
-
-
Guo, Z.1
Qian, L.2
Liu, R.3
Dai, H.4
Zhou, M.5
-
110
-
-
77956942874
-
Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
-
Guo Z, Zheng L, Xu H, Dai H, Zhou M, et al. 2010. Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding. Nat. Chem. Biol. 6:766-73
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 766-773
-
-
Guo, Z.1
Zheng, L.2
Xu, H.3
Dai, H.4
Zhou, M.5
-
111
-
-
79951573439
-
Functional regulation of FEN1 nuclease and its link to cancer
-
Zheng L, Jia J, Finger LD, Guo Z, Zer C, Shen B. 2011. Functional regulation of FEN1 nuclease and its link to cancer. Nucleic Acids Res. 39:781-94
-
(2011)
Nucleic Acids Res.
, Issue.39
, pp. 781-794
-
-
Zheng, L.1
Jia, J.2
Finger, L.D.3
Guo, Z.4
Zer, C.5
Shen, B.6
-
112
-
-
49449102611
-
Removal of oxidativeDNAdamage via FEN1-dependent long-patch base excision repair in human cellmitochondria
-
Liu P, Qian L, Sung JS, de Souza-Pinto NC, Zheng L, et al. 2008. Removal of oxidativeDNAdamage via FEN1-dependent long-patch base excision repair in human cellmitochondria. Mol. Cell. Biol. 28:4975-87
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4975-4987
-
-
Liu, P.1
Qian, L.2
Sung, J.S.3
De Souza-Pinto, N.C.4
Zheng, L.5
-
113
-
-
55049124777
-
Long patch base excision repair in mammalian mitochondrial genomes
-
Szczesny B, Tann AW, Longley MJ, Copeland WC, Mitra S. 2008. Long patch base excision repair in mammalian mitochondrial genomes. J. Biol. Chem. 283:26349-56
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26349-26356
-
-
Szczesny, B.1
Tann, A.W.2
Longley, M.J.3
Copeland, W.C.4
Mitra, S.5
-
114
-
-
70149110390
-
Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity
-
Kalifa L, Beutner G, Phadnis N, Sheu SS, Sia EA. 2009. Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity. DNA Repair 8:1242-49
-
(2009)
DNA Repair
, vol.8
, pp. 1242-1249
-
-
Kalifa, L.1
Beutner, G.2
Phadnis, N.3
Sheu, S.S.4
Sia, E.A.5
-
115
-
-
0032974345
-
Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27
-
Parenteau J, Wellinger RJ. 1999. Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27. Mol. Cell. Biol. 19:4143-52
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4143-4152
-
-
Parenteau, J.1
Wellinger, R.J.2
-
116
-
-
0036959004
-
Differential processing of leading- and lagging-strand ends at Saccharomyces cerevisiae telomeres revealed by the absence of Rad27p nuclease
-
Parenteau J, Wellinger RJ. 2002. Differential processing of leading- and lagging-strand ends at Saccharomyces cerevisiae telomeres revealed by the absence of Rad27p nuclease. Genetics 162:1583-94
-
(2002)
Genetics
, vol.162
, pp. 1583-1594
-
-
Parenteau, J.1
Wellinger, R.J.2
-
117
-
-
33750801681
-
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
-
Verdun RE, Karlseder J. 2006. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell 127:709-20
-
(2006)
Cell
, vol.127
, pp. 709-720
-
-
Verdun, R.E.1
Karlseder, J.2
-
118
-
-
31544482730
-
Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase β
-
Muftuoglu M, Wong HK, Imam SZ, Wilson DM 3rd, Bohr VA, Opresko PL. 2006. Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase β. Cancer Res. 66:113-24
-
(2006)
Cancer Res.
, vol.66
, pp. 113-124
-
-
Muftuoglu, M.1
Wong, H.K.2
Imam, S.Z.3
Wilson Iii, D.M.4
Bohr, V.A.5
Opresko, P.L.6
-
119
-
-
63649138336
-
Human flap endonuclease i is in complex with telomerase and is required for telomerase-mediated telomere maintenance
-
Sampathi S, Bhusari A, Shen B, Chai W. 2009. Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance. J. Biol. Chem. 284:3682-90
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3682-3690
-
-
Sampathi, S.1
Bhusari, A.2
Shen, B.3
Chai, W.4
-
120
-
-
41449108060
-
Flap endonuclease 1 contributes to telomere stability
-
Saharia A, Guittat L, Crocker S, Lim A, Steffen M, et al. 2008. Flap endonuclease 1 contributes to telomere stability. Curr. Biol. 18:496-500
-
(2008)
Curr. Biol.
, vol.18
, pp. 496-500
-
-
Saharia, A.1
Guittat, L.2
Crocker, S.3
Lim, A.4
Steffen, M.5
-
121
-
-
29244451512
-
The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA
-
Sharma S, Sommers JA, Gary RK, Friedrich-Heineken E, Hübscher U, Brosh RM Jr. 2005. The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA. Nucleic Acids Res. 33:6769-81
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 6769-6781
-
-
Sharma, S.1
Sommers, J.A.2
Gary, R.K.3
Friedrich-Heineken, E.4
Hübscher, U.5
Brosh Jr., R.M.6
-
122
-
-
77749239808
-
Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA
-
Vallur AC, Maizels N. 2010. Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA. PLoS ONE 5:e8908
-
(2010)
PLoS ONE
, vol.5
-
-
Vallur, A.C.1
Maizels, N.2
-
123
-
-
0033941545
-
Genetic analyses of Schizosaccharomyces pombe dna2+ reveal that Dna2 plays an essential role in Okazaki fragment metabolism
-
Kang HY, Choi E, Bae SH, Lee KH, Gim BS, et al. 2000. Genetic analyses of Schizosaccharomyces pombe dna2+ reveal that Dna2 plays an essential role in Okazaki fragment metabolism. Genetics 155:1055-67
-
(2000)
Genetics
, vol.155
, pp. 1055-1067
-
-
Kang, H.Y.1
Choi, E.2
Bae, S.H.3
Lee, K.H.4
Gim, B.S.5
-
124
-
-
84855378612
-
Functional FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal cancer, gastric cancer and colorectal cancer
-
Liu L, Zhou C, Zhou L, Peng L, Li D, et al. 2011. Functional FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal cancer, gastric cancer and colorectal cancer. Carcinogenesis 33:119-23
-
(2011)
Carcinogenesis
, vol.33
, pp. 119-123
-
-
Liu, L.1
Zhou, C.2
Zhou, L.3
Peng, L.4
Li, D.5
-
125
-
-
69549123990
-
Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk
-
Yang M, Guo H, Wu C, He Y, Yu D, et al. 2009. Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk. Hum. Mutat. 30:1320-28
-
(2009)
Hum. Mutat.
, vol.30
, pp. 1320-1328
-
-
Yang, M.1
Guo, H.2
Wu, C.3
He, Y.4
Yu, D.5
-
126
-
-
34447132813
-
Fen1 mutations result in autoimmunity, chronic inflammation and cancers
-
Zheng L, Dai H, Zhou M, Li M, Singh P, et al. 2007. Fen1 mutations result in autoimmunity, chronic inflammation and cancers. Nat. Med. 13:812-19
-
(2007)
Nat. Med.
, vol.13
, pp. 812-819
-
-
Zheng, L.1
Dai, H.2
Zhou, M.3
Li, M.4
Singh, P.5
-
127
-
-
49649100703
-
Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants
-
Larsen E, Kleppa L, Meza TJ, Meza-Zepeda LA, Rada C, et al. 2008. Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants. Cancer Res. 68:4571-79
-
(2008)
Cancer Res.
, vol.68
, pp. 4571-4579
-
-
Larsen, E.1
Kleppa, L.2
Meza, T.J.3
Meza-Zepeda, L.A.4
Rada, C.5
-
128
-
-
0031788197
-
Fen1 expression: A novel marker for cell proliferation
-
Warbrick E, Coates PJ, Hall PA. 1998. Fen1 expression: a novel marker for cell proliferation. J. Pathol. 186:319-24
-
(1998)
J. Pathol.
, vol.186
, pp. 319-324
-
-
Warbrick, E.1
Coates, P.J.2
Hall, P.A.3
-
129
-
-
0034678917
-
Gene expression of flap endonuclease-1 during cell proliferation and differentiation
-
Kim IS, Lee MY, Lee IH, Shin SL, Lee SY. 2000. Gene expression of flap endonuclease-1 during cell proliferation and differentiation. Biochim. Biophys. Acta 1496:333-40
-
(2000)
Biochim. Biophys. Acta
, vol.1496
, pp. 333-340
-
-
Kim, I.S.1
Lee, M.Y.2
Lee, I.H.3
Shin, S.L.4
Lee, S.Y.5
-
130
-
-
56449116122
-
Overexpression and hypomethylation of flap endonuclease 1 gene in breast and other cancers
-
Singh P, Yang M, Dai H, Yu D, Huang Q, et al. 2008. Overexpression and hypomethylation of flap endonuclease 1 gene in breast and other cancers. Mol. Cancer Res. 6:1710-17
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1710-1717
-
-
Singh, P.1
Yang, M.2
Dai, H.3
Yu, D.4
Huang, Q.5
-
131
-
-
9144241047
-
Highly expressed genes in pancreatic ductal adenocarcinomas: A comprehensive characterization and comparison of the transcription profiles obtained from three major technologies
-
Iacobuzio-Donahue CA, Ashfaq R, Maitra A, Adsay NV, Shen-Ong GL, et al. 2003. Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. Cancer Res. 63:8614-22
-
(2003)
Cancer Res.
, vol.63
, pp. 8614-8622
-
-
Iacobuzio-Donahue, C.A.1
Ashfaq, R.2
Maitra, A.3
Adsay, N.V.4
Shen-Ong, G.L.5
-
132
-
-
0242551649
-
Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer
-
Sato M, Girard L, Sekine I, Sunaga N, Ramirez RD, et al. 2003. Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer. Oncogene 22:7243-46
-
(2003)
Oncogene
, vol.22
, pp. 7243-7246
-
-
Sato, M.1
Girard, L.2
Sekine, I.3
Sunaga, N.4
Ramirez, R.D.5
-
133
-
-
19944425959
-
Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells
-
Kim JM, Sohn HY, Yoon SY, Oh JH, Yang JO, et al. 2005. Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells. Clin. Cancer Res. 11:473-82
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 473-482
-
-
Kim, J.M.1
Sohn, H.Y.2
Yoon, S.Y.3
Oh, J.H.4
Yang, J.O.5
-
134
-
-
69249161787
-
FEN1 is overexpressed in testis, lung and brain tumors
-
Nikolova T, Christmann M, Kaina B. 2009. FEN1 is overexpressed in testis, lung and brain tumors. Anticancer Res. 29:2453-59
-
(2009)
Anticancer Res.
, vol.29
, pp. 2453-2459
-
-
Nikolova, T.1
Christmann, M.2
Kaina, B.3
-
135
-
-
32844466059
-
Fen1 is induced p53 dependently and involved in the recovery from UV-light-induced replication inhibition
-
Christmann M, Tomicic MT, Origer J, Kaina B. 2005. Fen1 is induced p53 dependently and involved in the recovery from UV-light-induced replication inhibition. Oncogene 24:8304-13
-
(2005)
Oncogene
, vol.24
, pp. 8304-8313
-
-
Christmann, M.1
Tomicic, M.T.2
Origer, J.3
Kaina, B.4
-
136
-
-
55949114642
-
Effect of polyamine deficiency on proteins involved in Okazaki fragment maturation
-
Johansson VM, Miniotis MF, Hegardt C, Jonsson G, Staaf J, et al. 2008. Effect of polyamine deficiency on proteins involved in Okazaki fragment maturation. Cell Biol. Int. 32:1467-77
-
(2008)
Cell Biol. Int.
, vol.32
, pp. 1467-1477
-
-
Johansson, V.M.1
Miniotis, M.F.2
Hegardt, C.3
Jonsson, G.4
Staaf, J.5
-
137
-
-
0042091947
-
Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
-
Larsen E, Gran C, Saether BE, Seeberg E, Klungland A. 2003. Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage. Mol. Cell. Biol. 23:5346-53
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5346-5353
-
-
Larsen, E.1
Gran, C.2
Saether, B.E.3
Seeberg, E.4
Klungland, A.5
-
138
-
-
0030872252
-
Functional analysis of point mutations in human flap endonuclease-1 active site
-
Shen B, Nolan JP, Sklar LA, Park MS. 1997. Functional analysis of point mutations in human flap endonuclease-1 active site. Nucleic Acids Res. 25:3332-38
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3332-3338
-
-
Shen, B.1
Nolan, J.P.2
Sklar, L.A.3
Park, M.S.4
|