The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair

EMBO Journal

Volumn 21, Issue 21, 2002, Pages 5930-5942

  Storici, Francesca ^a   Henneke, Ghislaine ^a   Ferrari, Elena ^a   Gordenin, Dmitry A ^a   Hübscher, Ulrich ^a   Resnick, Michael A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

FEN1; Flap endonuclease; Loop domain; Repair; Replication

Indexed keywords

ENDONUCLEASE; MESYLIC ACID METHYL ESTER; PROTEIN FEN1; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DNA BINDING; DNA REPAIR; DNA REPLICATION; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME STRUCTURE; GENE EXPRESSION; GENETIC CONSERVATION; HUMAN; IN VIVO STUDY; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL;

BASE SEQUENCE; CATALYTIC DOMAIN; DNA; DNA REPAIR; DNA REPLICATION; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASE V; EXODEOXYRIBONUCLEASES; FLAP ENDONUCLEASES; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; MUTATION;

EID: 0036845404     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf587     Document Type: Article

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