β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16937-16948

  Poon, Wayne W ^a   Carlos, Anthony J ^a   Aguilar, Brittany L ^a   Berchtold, Nicole C ^a   Kawano, Crystal K ^a   Zograbyan, Vahe ^a   Yaopruke, Tim ^a   Shelanski, Michael ^b   Cotman, Carl W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROLASES; NEURONS; OLIGOMERS;

BRAIN-DERIVED NEUROTROPHIC FACTORS; CULTURE CHAMBERS; DEUBIQUITINATING ENZYMES; ENDOSOMAL VESICLES; NEURONAL SURVIVAL; NEUROTROPHIN RECEPTOR; SYNAPTIC PLASTICITY; TRANSGENIC MICE;

SIGNALING;

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 7; OLIGOMER; UBIQUITIN CARBOXY TERMINAL HYDROLASE L1; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CELL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME METABOLISM; GENE CONTROL; GENE EXPRESSION; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

MUS MUSCULUS;

EID: 84878766949     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.463711     Document Type: Article

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