Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling

Journal of Neurochemistry

Volumn 117, Issue 3, 2011, Pages 479-493

  Georgieva, Maya V ^a   De Pablo, Yolanda ^a,c   Sanchis, Daniel ^a   Comella, Joan X ^b   Llovera, Marta ^a  

^a UNIVERSITY OF LLEIDA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

degradation; differentiation; neurotrophin receptor; trafficking; ubiquitin ligase; ubiquitination

Indexed keywords

NEURAL PRECURSOR CELL EXPRESSED DEVELOPMENTALLY DOWN REGULATED 4-2 PROTEIN; PROTEIN TYROSINE KINASE A; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVITY; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOPRECIPITATION; LYSOSOME; MUTANT; NERVE FIBER GROWTH; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION; WILD TYPE;

ANIMALS; BIOTIN; CELL DIFFERENTIATION; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; GREEN FLUORESCENT PROTEINS; IMMUNOPRECIPITATION; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MUTATION; NERVE GROWTH FACTOR; PC12 CELLS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN TRANSPORT; RAB4 GTP-BINDING PROTEINS; RAB5 GTP-BINDING PROTEINS; RATS; RECEPTOR, TRKA; SIGNAL TRANSDUCTION; TRANSFECTION; UBIQUITINATION;

EID: 79954415391     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07218.x     Document Type: Article

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