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Volumn 19, Issue 12, 1999, Pages 4972-4983

Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice

Author keywords

BDNF; Hippocampus; Knockout mice; Synaptic fatigue; Synaptobrevin; Synaptophysin; Vesicle docking

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; SYNAPTOBREVIN; SYNAPTOPHYSIN;

EID: 0033564051     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-12-04972.1999     Document Type: Article
Times cited : (411)

References (58)
  • 1
    • 0029974547 scopus 로고    scopus 로고
    • Neurotrophins and activity-dependent development of the neocortex
    • Bonhoeffer T (1996) Neurotrophins and activity-dependent development of the neocortex. Curr Opin Neurobiol 6:119-126.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 119-126
    • Bonhoeffer, T.1
  • 3
    • 0028916607 scopus 로고
    • Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF
    • Cabelli RJ, Horn A, Shatz CJ (1995) Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF. Science 267:1662-1666.
    • (1995) Science , vol.267 , pp. 1662-1666
    • Cabelli, R.J.1    Horn, A.2    Shatz, C.J.3
  • 4
    • 0027971368 scopus 로고
    • Vesicle-associated membrane protein and synaptophysin are associated on the synaptic vesicle
    • Calakos N, Scheller RH (1994) Vesicle-associated membrane protein and synaptophysin are associated on the synaptic vesicle. J Biol Chem 269:24534-24537.
    • (1994) J Biol Chem , vol.269 , pp. 24534-24537
    • Calakos, N.1    Scheller, R.H.2
  • 5
    • 0030051050 scopus 로고    scopus 로고
    • Synaptic vesicle biogenesis, docking, and fusion: A molecular description
    • Calakos N, Scheller RH (1996) Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiol Rev 76:1-29.
    • (1996) Physiol Rev , vol.76 , pp. 1-29
    • Calakos, N.1    Scheller, R.H.2
  • 6
    • 0028350057 scopus 로고
    • Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking
    • Calakos N, Bennett MK, Peterson KE, Scheller RH (1994) Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. Science 263:1146-1149.
    • (1994) Science , vol.263 , pp. 1146-1149
    • Calakos, N.1    Bennett, M.K.2    Peterson, K.E.3    Scheller, R.H.4
  • 9
    • 0018908710 scopus 로고
    • Paired pulse and frequency facilitation in the CA1 region of the in vitro rat hippocampus
    • Creager R, Dunwiddie T, Lynch G (1980) Paired pulse and frequency facilitation in the CA1 region of the in vitro rat hippocampus. J Physiol (Lond) 299:409-424.
    • (1980) J Physiol (Lond) , vol.299 , pp. 409-424
    • Creager, R.1    Dunwiddie, T.2    Lynch, G.3
  • 10
    • 0020696351 scopus 로고
    • Structural changes during transmitter release at synapses in the frog sympathetic ganglion
    • Dickinson-Nelson A, Reese TS (1983) Structural changes during transmitter release at synapses in the frog sympathetic ganglion. J Neurosci 3:42-52.
    • (1983) J Neurosci , vol.3 , pp. 42-52
    • Dickinson-Nelson, A.1    Reese, T.S.2
  • 11
    • 0030919664 scopus 로고    scopus 로고
    • Heterogeneity of release probability, facilitation, and depletion at central synapses
    • Dobrunz LE, Stevens CF (1997) Heterogeneity of release probability, facilitation, and depletion at central synapses. Neuron 18:995-1008.
    • (1997) Neuron , vol.18 , pp. 995-1008
    • Dobrunz, L.E.1    Stevens, C.F.2
  • 12
    • 0028274040 scopus 로고
    • Mice lacking brain-derived neurotrophic factor develop with sensory deficits
    • Ernfors P, Lee K-F, Jaenisch R (1994) Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368:147-150.
    • (1994) Nature , vol.368 , pp. 147-150
    • Ernfors, P.1    Lee, K.-F.2    Jaenisch, R.3
  • 13
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov A, Pozzo-Miller L, Olafsson P, Wang T, Lu B (1996) Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381:706-709.
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo-Miller, L.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 14
    • 0032429305 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus
    • Frerking M, Malenka RC, Nicoll RA (1998) Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. J Neurophysiol 80:3383-3386.
    • (1998) J Neurophysiol , vol.80 , pp. 3383-3386
    • Frerking, M.1    Malenka, R.C.2    Nicoll, R.A.3
  • 15
    • 0025817447 scopus 로고
    • Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain
    • Friedman WJ, Olson L, Persson H (1991) Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain. Eur J Neurosci 3:688-697.
    • (1991) Eur J Neurosci , vol.3 , pp. 688-697
    • Friedman, W.J.1    Olson, L.2    Persson, H.3
  • 17
    • 17344369060 scopus 로고    scopus 로고
    • Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus
    • Gottschalk W, Pozzo-Miller LD, Figurov A, Lu B (1998) Presynaptic modulation of synaptic transmission and plasticity by brain-derived neurotrophic factor in the developing hippocampus. J Neurosci 18:6830-6839.
    • (1998) J Neurosci , vol.18 , pp. 6830-6839
    • Gottschalk, W.1    Pozzo-Miller, L.D.2    Figurov, A.3    Lu, B.4
  • 18
    • 0001209075 scopus 로고
    • Electron microscopy of presynaptic organelles of the spinal cord
    • Gray EG (1963) Electron microscopy of presynaptic organelles of the spinal cord. J Anat 97:101-106.
    • (1963) J Anat , vol.97 , pp. 101-106
    • Gray, E.G.1
  • 19
    • 0028130728 scopus 로고
    • Synaptic vesicle membrane fusion complex: Action of clostridial neurotoxins on assembly
    • Hayashi T, McMahon H, Yamasaki S, Binz T, Hata Y, Sudhof TC, Niemann H (1994) Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly. EMBO J 13:5051-5061.
    • (1994) EMBO J , vol.13 , pp. 5051-5061
    • Hayashi, T.1    McMahon, H.2    Yamasaki, S.3    Binz, T.4    Hata, Y.5    Sudhof, T.C.6    Niemann, H.7
  • 20
    • 0015619310 scopus 로고
    • Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction
    • Heuser JE, Reese TS (1973) Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction. J Cell Biol 57:315-344.
    • (1973) J Cell Biol , vol.57 , pp. 315-344
    • Heuser, J.E.1    Reese, T.S.2
  • 21
    • 0344169506 scopus 로고
    • Synaptic-vesicle exocytosis captured by quick freezing
    • (Schmitt FO, Worden FG, eds), Cambridge, MA: MIT
    • Heuser JE, Reese TS (1979) Synaptic-vesicle exocytosis captured by quick freezing. In: The neurosciences: fourth study program (Schmitt FO, Worden FG, eds), pp 573-600. Cambridge, MA: MIT.
    • (1979) The Neurosciences: Fourth Study Program , pp. 573-600
    • Heuser, J.E.1    Reese, T.S.2
  • 22
    • 0016839286 scopus 로고
    • Fatigue and recovery of transmission at the Mauthner fiber-giant fiber synapse of the hatchet-fish
    • Highstein SM, Bennnet MVL (1975) Fatigue and recovery of transmission at the Mauthner fiber-giant fiber synapse of the hatchet-fish. Brain Res 98:229-242.
    • (1975) Brain Res , vol.98 , pp. 229-242
    • Highstein, S.M.1    Bennnet, M.V.L.2
  • 23
    • 0031748884 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex
    • Huber KM, Sawtell NB, Bear MF (1998) Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology 37:571-579.
    • (1998) Neuropharmacology , vol.37 , pp. 571-579
    • Huber, K.M.1    Sawtell, N.B.2    Bear, M.F.3
  • 25
    • 0025883295 scopus 로고
    • BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF
    • Isackson PJ, Huntsman MM, Murray KD, Gall CM (1991) BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron 6:937-948.
    • (1991) Neuron , vol.6 , pp. 937-948
    • Isackson, P.J.1    Huntsman, M.M.2    Murray, K.D.3    Gall, C.M.4
  • 26
    • 0028351190 scopus 로고
    • Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
    • Jones KR, Farinas I, Backus C, Reichardt LF (1994) Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76:989-999.
    • (1994) Cell , vol.76 , pp. 989-999
    • Jones, K.R.1    Farinas, I.2    Backus, C.3    Reichardt, L.F.4
  • 27
    • 0028988240 scopus 로고
    • Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus
    • Kang H, Schuman EM (1995) Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 267:1658-1662.
    • (1995) Science , vol.267 , pp. 1658-1662
    • Kang, H.1    Schuman, E.M.2
  • 29
    • 0028266334 scopus 로고
    • Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus
    • Knipper M, da Penha Berzaghi M, Blochl A, Breer H, Thoenen H, Lindholm D (1994) Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci 6:668-671.
    • (1994) Eur J Neurosci , vol.6 , pp. 668-671
    • Knipper, M.1    Da Penha Berzaghi, M.2    Blochl, A.3    Breer, H.4    Thoenen, H.5    Lindholm, D.6
  • 30
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
    • Korte M, Carroll P, Wolf E, Brem G, Thoenen H, Bonhoeffer T (1995) Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci USA 92:8856-8860.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4    Thoenen, H.5    Bonhoeffer, T.6
  • 31
    • 0029910815 scopus 로고    scopus 로고
    • Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice
    • Korte M, Griesbeck O, Gravel C, Carroll P, Staiger V, Thoenen H, Bonhoeffer T (1996) Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci USA 93:12547-12552.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12547-12552
    • Korte, M.1    Griesbeck, O.2    Gravel, C.3    Carroll, P.4    Staiger, V.5    Thoenen, H.6    Bonhoeffer, T.7
  • 32
    • 0028590148 scopus 로고
    • BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurons
    • Lessmann V, Gottmann K, Heumann R (1994) BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurons. NeuroReport 6:21-25.
    • (1994) Neuroreport , vol.6 , pp. 21-25
    • Lessmann, V.1    Gottmann, K.2    Heumann, R.3
  • 33
    • 0029099174 scopus 로고
    • Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors
    • Levine ES, Dreyfus CF, Black IB, Plummer MR (1995) Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc Natl Acad Sci USA 92:8074-8077.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8074-8077
    • Levine, E.S.1    Dreyfus, C.F.2    Black, I.B.3    Plummer, M.R.4
  • 34
    • 0028810239 scopus 로고
    • Neurotrophic factors and synaptic plasticity
    • Lo DC (1995) Neurotrophic factors and synaptic plasticity. Neuron 15:979-981.
    • (1995) Neuron , vol.15 , pp. 979-981
    • Lo, D.C.1
  • 35
    • 0030767944 scopus 로고    scopus 로고
    • Role of neurotrophins in synapse development and plasticity
    • Lu B, Figurov A (1997) Role of neurotrophins in synapse development and plasticity. Rev Neurosci 8:1-12.
    • (1997) Rev Neurosci , vol.8 , pp. 1-12
    • Lu, B.1    Figurov, A.2
  • 38
    • 0018386142 scopus 로고
    • Stereological approach to the study of synapse morphometry with particular regard to estimating number in a volume and on a surface
    • Mayhew TM (1979) Stereological approach to the study of synapse morphometry with particular regard to estimating number in a volume and on a surface. J Neurocytol 8:121-138.
    • (1979) J Neurocytol , vol.8 , pp. 121-138
    • Mayhew, T.M.1
  • 39
    • 0028858681 scopus 로고
    • Neurotrophins regulate dendritic growth in developing visual cortex
    • McAllister AK, Lo DC, Katz LC (1995) Neurotrophins regulate dendritic growth in developing visual cortex. Neuron 15:791-803.
    • (1995) Neuron , vol.15 , pp. 791-803
    • McAllister, A.K.1    Lo, D.C.2    Katz, L.C.3
  • 41
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
    • Patterson S, Grover LM, Schwartzkroin PA, Bothwell M (1992) Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron 9:1081-1088.
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 42
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • Patterson SL, Abel T, Deuel TA, Martin KC, Rose JC, Kandel ER (1996) Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16:1137-1145.
    • (1996) Neuron , vol.16 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 43
    • 0029118637 scopus 로고
    • Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion
    • Pellegrini LL, O'Connor V, Lottspeich F, Betz H (1995) Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion. EMBO J 14:4705-4713.
    • (1995) EMBO J , vol.14 , pp. 4705-4713
    • Pellegrini, L.L.1    O'Connor, V.2    Lottspeich, F.3    Betz, H.4
  • 45
    • 0032188811 scopus 로고    scopus 로고
    • Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila
    • Reist NE, Buchanan J, Li J, DiAntonio A, Buxton EM, Schwarz TL (1998) Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila. J Neurosci 18:7662-7673.
    • (1998) J Neurosci , vol.18 , pp. 7662-7673
    • Reist, N.E.1    Buchanan, J.2    Li, J.3    DiAntonio, A.4    Buxton, E.M.5    Schwarz, T.L.6
  • 46
    • 0027487057 scopus 로고
    • The kinetics of synaptic vesicle recycling measured at single presynaptic boutons
    • Ryan TA, Reuter H, Wendland B, Schweizer FE, Tsien RW, Smith SJ (1993) The kinetics of synaptic vesicle recycling measured at single presynaptic boutons. Neuron 11:713-724.
    • (1993) Neuron , vol.11 , pp. 713-724
    • Ryan, T.A.1    Reuter, H.2    Wendland, B.3    Schweizer, F.E.4    Tsien, R.W.5    Smith, S.J.6
  • 48
    • 0030820683 scopus 로고    scopus 로고
    • Quantitative ultrastructural analysis of hippocampal excitatory synapses
    • Schikorski T, Stevens CF (1997) Quantitative ultrastructural analysis of hippocampal excitatory synapses. J Neurosci 17:5858-5867.
    • (1997) J Neurosci , vol.17 , pp. 5858-5867
    • Schikorski, T.1    Stevens, C.F.2
  • 49
    • 0030048838 scopus 로고    scopus 로고
    • Calcium dependent interaction of neuronal N-type calcium channels with presynaptic fusion proteins
    • Sheng Z, Rettig J, Cook T, Catterall WA (1996) Calcium dependent interaction of neuronal N-type calcium channels with presynaptic fusion proteins. Nature 379:451-454.
    • (1996) Nature , vol.379 , pp. 451-454
    • Sheng, Z.1    Rettig, J.2    Cook, T.3    Catterall, W.A.4
  • 50
    • 0027517462 scopus 로고
    • A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
    • Sollner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE (1993) A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75:409-418.
    • (1993) Cell , vol.75 , pp. 409-418
    • Sollner, T.1    Bennett, M.K.2    Whiteheart, S.W.3    Scheller, R.H.4    Rothman, J.E.5
  • 51
    • 0028957942 scopus 로고
    • Facilitation and depression at single central synapses
    • Stevens CF, Wang Y (1995) Facilitation and depression at single central synapses. Neuron 14:795-802.
    • (1995) Neuron , vol.14 , pp. 795-802
    • Stevens, C.F.1    Wang, Y.2
  • 52
    • 0029026392 scopus 로고
    • The synaptic vesicle cycle: A cascade of protein-protein interactions
    • Sudhof TC (1995) The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375:645-653.
    • (1995) Nature , vol.375 , pp. 645-653
    • Sudhof, T.C.1
  • 53
    • 0030612039 scopus 로고    scopus 로고
    • A synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus
    • A synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus. J Neurosci 17:2959-2966.
    • (1997) J Neurosci , vol.17 , pp. 2959-2966
    • Tanaka, T.1    Saito, H.2    Matsuki, N.3
  • 54
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • Thoenen H (1995) Neurotrophins and neuronal plasticity. Science 270:593-596.
    • (1995) Science , vol.270 , pp. 593-596
    • Thoenen, H.1
  • 55
    • 0028942065 scopus 로고
    • Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysin
    • Washbourne P, Schiavo G, Montecucco C (1995) Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysin. Biochem J 305:721-724.
    • (1995) Biochem J , vol.305 , pp. 721-724
    • Washbourne, P.1    Schiavo, G.2    Montecucco, C.3
  • 57
    • 0025084077 scopus 로고
    • Activity-dependent regulation of BDNF and NGF mRNA in the rat hippocampus is mediated by non-NMDA glutamate receptors
    • Zafra F, Hengerer B, Leibrock J, Thoenen H, Lindholm D (1990) Activity-dependent regulation of BDNF and NGF mRNA in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J 9:3545-3550.
    • (1990) EMBO J , vol.9 , pp. 3545-3550
    • Zafra, F.1    Hengerer, B.2    Leibrock, J.3    Thoenen, H.4    Lindholm, D.5
  • 58
    • 0024600340 scopus 로고
    • Short-term synaptic plasticity
    • Zucker RS (1989) Short-term synaptic plasticity. Annu Rev Neurosci 12:13-31.
    • (1989) Annu Rev Neurosci , vol.12 , pp. 13-31
    • Zucker, R.S.1


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